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Zerobase Emollient Cream- 500g

Zerobase Emollient Cream- 500g

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  • ✔️ Soothes and moisturises dry, itchy skin caused by eczema
  • ✔️ Fragrance-free and paraben-free — ideal for sensitive skin
  • ✔️ Suitable for adults, children, and infants with dry skin conditions
  • ✔️ Can be used as a soap substitute to protect the skin barrier
  • ✔️ Large 500g tub provides long-lasting supply for daily use

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What Is Zerobase Emollient Cream and How Does It Help Dry Skin?

 

If you live with eczema, psoriasis, or persistently dry skin, you'll know how uncomfortable — and sometimes relentless — the itch and tightness can feel. Zerobase emollient cream is a fragrance-free, paraben-free moisturising cream designed to soothe, soften, and protect dry, flaky, or irritated skin. Available in a generous 500g tub, it offers excellent value for those who need to apply emollients regularly throughout the day. You can explore the full range of creams and ointments available at Cured Pharmacy if you're looking for additional skin treatments alongside this product.

Emollients are a cornerstone of dry skin management recommended by the NHS. They work by moisturising the skin and helping to maintain the skin's natural barrier — something that becomes compromised in conditions like eczema and psoriasis. Zerobase is a well-established emollient that is widely used across all age groups, from infants to older adults.

 

How Does Zerobase Emollient Cream Work on the Skin?

 

The active ingredient in Zerobase is liquid paraffin 6% w/w. Liquid paraffin is an occlusive agent — it sits on the surface of the skin and forms a thin, protective film that slows down water evaporation. This helps the skin retain moisture, reducing dryness, flaking, and the urge to scratch.

  • Forms a protective barrier on the skin surface to lock in moisture
  • Reduces transepidermal water loss (TEWL), a key driver of dry skin conditions
  • Softens and smooths rough, flaky skin with regular use
  • Soothes irritation and reduces the sensation of tightness or itching
  • Supports the skin's natural barrier function over time

Because it contains no fragrances, dyes, or parabens, it is less likely to trigger allergic reactions — a real concern for people with sensitive or reactive skin.

 

Who Should Use Zerobase Emollient Cream?

 

Zerobase emollient cream is suitable for a wide range of people. It is particularly useful for anyone whose skin barrier is compromised or who experiences chronic dryness. The NHS recommends emollients as a first-line treatment for conditions like eczema and psoriasis, and Zerobase fits neatly into that guidance.

  • Adults and children with eczema or atopic dermatitis
  • People with psoriasis who need regular moisturisation
  • Anyone with dry, cracked heels or rough skin on the hands and feet
  • Those with sensitive skin who cannot tolerate fragranced products
  • Older adults whose skin naturally produces less oil with age

It can also be used as a soap substitute during bathing or showering, which is particularly helpful for people with eczema who find conventional soaps drying and irritating.

 

How Does Zerobase Emollient Cream Compare to Other Emollients?

 

Feature Zerobase Emollient Cream 500g Aqueous Cream BP
Active ingredient Liquid paraffin 6% w/w Emulsifying ointment 30% w/w
Fragrance-free Yes Yes
Paraben-free Yes No (contains preservatives)
Suitable as soap substitute Yes Yes (though NHS advises caution)
Pack size 500g Typically 100g–500g

 

Is Zerobase Emollient Cream Safe for Long-Term Use?

 

Yes. Because zerobase emollient cream contains no steroids and no harsh preservatives, it is considered safe for long-term, daily use. The NHS advises that emollients should be used regularly and generously — not just when the skin flares up — to maintain the skin barrier and prevent dryness from returning. If you're also managing a skin condition that requires medicated treatment, you can browse our skin care collection for complementary products.

Store the cream below 25°C, away from direct sunlight. Keep the lid tightly closed between uses to prevent contamination. Always wash your hands before applying, or use a clean spatula to remove cream from the tub.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Zerobase Emollient Cream 500g specifications
Treatment category Emollient / Moisturiser
Mechanism of action Occlusive barrier — reduces transepidermal water loss
Effective for Dry skin, eczema, psoriasis, ichthyosis, cracked heels
Suitable for Adults, children, and infants (under medical guidance)
Active ingredient Liquid paraffin 6% w/w
Pack size 500g
UK classification General Sale List (GSL)
Drug class Emollient
Preparation Cream
Route of administration Topical (applied to skin)

Specifications of Zerobase Emollient Cream 500g

 

What Is Zerobase Emollient Cream and What Is It Used For?

 

Zerobase Emollient Cream is a topical moisturiser containing liquid paraffin 6% w/w as its active ingredient. It is used to manage and relieve the symptoms of dry skin conditions, including eczema, psoriasis, ichthyosis, and pruritus (itching). It can also be used as a soap substitute during washing, which helps avoid the drying effects of conventional soaps and detergents on already sensitive skin.

The NHS recommends that people with eczema use emollients every day, even when the skin appears clear, to help maintain the skin barrier and reduce the frequency of flare-ups. Zerobase is a leave-on emollient, meaning it is applied directly to the skin and left in place — it is not rinsed off unless used as a wash product.

 

What Do You Need to Know Before Using Zerobase Emollient Cream?

 

Zerobase Emollient Cream is generally well tolerated, but there are some important things to be aware of before you start using it.

Do not use Zerobase Emollient Cream if you:

  • Are allergic to liquid paraffin or any other ingredient in the formulation
  • Have a known hypersensitivity to any component of the cream

Warnings and precautions:

  • Emollient products can make surfaces slippery — take care in the bath or shower
  • Clothing, bedding, and dressings that have come into contact with emollients are a fire hazard; keep away from naked flames and do not smoke while using this product
  • Avoid contact with the eyes
  • Do not apply to broken, infected, or weeping skin without medical advice
  • If your skin condition worsens or does not improve after two weeks, consult your GP

Drug interactions:

  • No significant drug interactions are known for topical liquid paraffin emollients
  • If you are using a topical corticosteroid or other medicated cream, apply Zerobase first and allow it to absorb before applying the medicated product, or follow your prescriber's instructions

 

How Should You Use Zerobase Emollient Cream?

 

Using an emollient correctly makes a real difference to how effective it is. Apply generously and regularly — the NHS advises that people with eczema may need to use 250–500g of emollient per week to manage their condition properly.

  1. Wash your hands thoroughly before applying the cream
  2. Use a clean spatula or spoon to remove cream from the tub — this prevents contamination
  3. Apply the cream in smooth, downward strokes in the direction of hair growth to reduce the risk of folliculitis
  4. Apply to all affected areas of skin, including the face if needed (avoiding the eyes)
  5. Allow the cream to absorb before dressing or applying any other topical product
  6. Repeat two to four times daily, or as directed by your doctor or pharmacist
Indication Age Group Dose Frequency
Dry skin / eczema Adults Apply liberally to affected areas 2–4 times daily
Dry skin / eczema Children Apply liberally to affected areas 2–4 times daily
Soap substitute All ages Apply to wet skin, rinse off At each wash
Psoriasis (moisturisation) Adults Apply liberally to affected areas 2–4 times daily

If you are managing a more complex skin condition alongside dry skin, you may also find it helpful to browse our skin care collection for additional support products.

 

What Are the Possible Side Effects of Zerobase Emollient Cream?

 

Side effects with Zerobase Emollient Cream are uncommon. Because it is fragrance-free and paraben-free, it is less likely to cause reactions than many other moisturisers. However, as with any topical product, some people may experience a reaction.

Common side effects:

  • Mild stinging or burning sensation on first application, particularly on broken or very dry skin
  • Temporary greasiness or heaviness on the skin surface

Less common side effects:

  • Skin rash or redness at the application site
  • Folliculitis (inflammation of hair follicles) — more likely if cream is applied against the direction of hair growth or under occlusive dressings
  • Contact dermatitis in rare cases of sensitivity to an excipient

If you notice any signs of an allergic reaction — such as hives, swelling, or difficulty breathing — stop using the product immediately and seek medical attention. For foot-related dryness and cracking, you might also want to explore our foot care range for targeted treatments.

 

How Should You Store Zerobase Emollient Cream?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the lid tightly closed after each use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tub
  • Do not freeze
  • Do not transfer to another container

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Zerobase Emollient Cream online in the UK?

You can buy Zerobase Emollient Cream 500g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £9.56. No prescription is needed, and it is available for delivery across the UK. It is classified as a General Sale List (GSL) medicine, so it is available without a prescription.

How does Zerobase Emollient Cream work on dry skin?

Zerobase Emollient Cream works by forming an occlusive film on the skin surface using its active ingredient, liquid paraffin 6% w/w. This film slows down transepidermal water loss, helping the skin retain moisture and feel softer. With regular use, it helps restore and maintain the skin's natural barrier function, which is often compromised in conditions like eczema and psoriasis.

How do I use Zerobase Emollient Cream step by step?

Apply Zerobase Emollient Cream by first washing your hands, then using a clean spatula to scoop out the cream. Smooth it gently onto the affected skin in the direction of hair growth, and allow it to absorb before dressing. Repeat two to four times daily, or as directed by your pharmacist or GP.

How often should I apply Zerobase Emollient Cream?

The NHS recommends applying emollients frequently — typically two to four times a day — even when your skin feels relatively comfortable. Consistency is key; applying only during flare-ups is less effective than maintaining a regular routine. Your GP or pharmacist may advise a specific frequency based on the severity of your condition.

Is Zerobase Emollient Cream suitable for children and babies?

Yes, Zerobase Emollient Cream can be used on children and infants, but you should always consult a GP or pharmacist before applying any emollient to a baby or young child. It is fragrance-free and paraben-free, which makes it gentler on sensitive young skin. If your child has eczema, the NHS recommends using emollients as a core part of their daily skin care routine.

Does Zerobase Emollient Cream contain steroids?

No, Zerobase Emollient Cream does not contain any steroids. It is a plain emollient moisturiser and is safe for long-term daily use without the risks associated with topical corticosteroids. If you need a steroid cream for a flare-up, your GP can prescribe one separately to use alongside your emollient.

Can I use Zerobase Emollient Cream on my face?

Yes, Zerobase Emollient Cream can generally be applied to the face, but you should take care to avoid contact with the eyes. If you have a specific facial skin condition such as facial eczema or rosacea, it is worth speaking to your GP or pharmacist before use. The fragrance-free formula makes it less likely to irritate sensitive facial skin.

What are the side effects of Zerobase Emollient Cream?

Side effects are uncommon but can include mild stinging or burning on first application, particularly on very dry or broken skin. In rare cases, some people may experience a skin rash, redness, or folliculitis (inflammation of hair follicles). If you notice any signs of an allergic reaction, stop using the product and speak to your pharmacist or GP.

Can Zerobase Emollient Cream be used as a soap substitute?

Yes, Zerobase Emollient Cream can be used as a soap substitute during bathing or showering. Apply it to wet skin, gently massage in, and rinse off — this cleanses the skin without stripping away its natural oils. The NHS recommends using emollients as soap substitutes for people with eczema, as conventional soaps can worsen dryness and irritation.

Is Zerobase Emollient Cream fragrance-free and paraben-free?

Yes, Zerobase Emollient Cream is both fragrance-free and paraben-free, making it a good choice for people with sensitive or reactive skin. Fragrances and parabens are common triggers for contact dermatitis and skin irritation, so avoiding them is particularly important for eczema-prone skin. This also makes it suitable for use on children.

How long can I use Zerobase Emollient Cream for?

Zerobase Emollient Cream is safe for long-term, continuous use. Because it contains no steroids or harsh preservatives, there is no time limit on how long you can use it. The NHS advises that emollients should be used as part of an ongoing daily routine rather than just during flare-ups, to keep the skin barrier healthy over time.

What are the alternatives to Zerobase Emollient Cream?

Common alternatives include Diprobase Cream, Doublebase Gel, E45 Cream, and Cetraben Emollient Cream — all of which are available over the counter. The right emollient for you depends on your skin type and personal preference; some people prefer a lighter lotion while others need a thicker cream. You can explore a range of options in our creams and ointments collection.

Is there a fire risk with Zerobase Emollient Cream?

Yes — this is an important safety point. Emollient products containing paraffin, including Zerobase, can soak into clothing, bedding, and dressings and create a fire hazard. You should keep away from naked flames, open fires, and cigarettes while wearing clothing or using bedding that may have been in contact with the cream. Wash clothing and bedding regularly to reduce this risk.

Can I use Zerobase Emollient Cream with other skin treatments?

Yes, Zerobase Emollient Cream can be used alongside other topical treatments such as corticosteroid creams. As a general rule, apply the emollient first and allow it to absorb for around 30 minutes before applying any medicated cream, or follow the specific advice of your GP or pharmacist. If you are managing a complex skin condition, our skin care collection includes a range of complementary products.

What is the latest guidance on using emollients for eczema?

Current NHS and NICE guidance continues to recommend emollients as the foundation of eczema management, used daily and generously regardless of whether the skin is flaring. Research consistently shows that regular emollient use reduces the frequency and severity of eczema flare-ups and can reduce the need for topical steroids over time. Always follow the advice of your GP or dermatologist for your individual treatment plan.

How Should You Use Zerobase Emollient Cream?

Applying Zerobase Emollient Cream correctly helps you get the most out of it. The NHS recommends applying emollients generously and frequently — not just when your skin feels at its worst, but as part of a consistent daily routine.

Follow these steps each time you apply:

What Is the Correct Dose of Zerobase Emollient Cream?

There is no fixed dose for emollients in the same way as for oral medicines — the key principle is to apply liberally and often. The NHS advises that adults with eczema may need 250–500g of emollient per week, which is why the 500g tub offers such good value for regular users.

Use the table below as a general guide:

When Is the Best Time to Use Zerobase Emollient Cream?

The best times to apply Zerobase Emollient Cream are immediately after bathing or showering, when the skin is still slightly damp — this helps lock in moisture more effectively. Applying before bed is also beneficial, as the skin has time to absorb the cream overnight without being disturbed by washing or activity.

If you are using a topical corticosteroid or other medicated cream, apply Zerobase first and wait at least 30 minutes before applying the medicated product, unless your prescriber advises otherwise.

How Long Can You Use Zerobase Emollient Cream For?

Zerobase Emollient Cream is safe for long-term, continuous use. Because it contains no steroids, there is no restriction on how long you can use it. The NHS recommends treating emollients as a permanent part of your skin care routine rather than a short-term fix — stopping use when the skin improves often leads to dryness returning.

If your skin condition does not improve after two weeks of regular use, or if it worsens at any point, speak to your GP or pharmacist for further advice.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Zerobase Emollient Cream?

Zerobase Emollient Cream is generally very well tolerated, and most people use it without experiencing any side effects. However, as with any topical product, some people may notice mild reactions, particularly when first starting treatment or if the skin is already very dry or broken.

  • Mild stinging or burning sensation on first application to dry or broken skin
  • Temporary greasiness or heaviness on the skin surface
  • Slight slipperiness on the skin, particularly in the bath or shower

What Are the Less Common Side Effects of Zerobase Emollient Cream?

Less common side effects are rare but worth being aware of. These are more likely to occur if the cream is applied incorrectly or if you have a sensitivity to one of the excipients in the formulation.

  • Skin rash or redness at the site of application
  • Folliculitis — inflammation of the hair follicles, more likely if cream is applied against the direction of hair growth or under occlusive dressings
  • Contact dermatitis in rare cases of sensitivity to an ingredient
  • Worsening of existing skin condition in very rare cases

What Are the Serious Side Effects of Zerobase Emollient Cream?

Serious side effects are extremely rare with Zerobase Emollient Cream. However, you should be aware of the signs of a serious allergic reaction (anaphylaxis), which — though very unlikely — can occur with any topical product. Seek emergency medical help immediately if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin rash, hives, or blistering
  • Dizziness or feeling faint

What Should You Do If You Experience Side Effects of Zerobase Emollient Cream?

If you notice mild irritation or redness, try applying a smaller amount less frequently and see if the reaction settles. If the irritation persists or worsens, stop using the cream and speak to your pharmacist or GP. They may recommend an alternative emollient that suits your skin better.

You can report suspected side effects of any medicine in the UK through the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve safety monitoring for all patients.

Can Zerobase Emollient Cream Interact With Other Medicines?

No significant drug interactions are known for Zerobase Emollient Cream when used as directed. Because it is applied topically and is not absorbed into the bloodstream in meaningful amounts, it is unlikely to interact with oral medicines. If you are using other topical treatments — such as corticosteroid creams, calcineurin inhibitors, or antifungal creams — apply Zerobase first and allow it to absorb before applying the other product, or follow your prescriber's specific instructions.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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