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O’Keeffes Working Hands 60g Tube

O’Keeffes Working Hands 60g Tube

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  • ✔️ Repairs severely dry, cracked, and split hand skin
  • ✔️ Fragrance-free formula suits sensitive skin types
  • ✔️ Non-greasy finish absorbs quickly after application
  • ✔️ Glycerin and allantoin restore the skin moisture barrier
  • ✔️ Concentrated formula — small amount treats both hands

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What Is O'Keeffe's Working Hands Cream?

 

If your hands are constantly dry, cracked, or rough — whether from manual work, frequent handwashing, or cold weather — you'll know how uncomfortable and even painful that can be. O'Keeffe's Working Hands cream is a concentrated, fragrance-free hand cream specifically formulated to repair severely dry and damaged skin. At just £6.40 for a 60g tube, it offers an accessible, no-fuss solution that fits easily into a daily routine. You can browse our full range of skin care products at Cured Pharmacy if you're looking for complementary options alongside this cream.

The cream is particularly popular with tradespeople, healthcare workers, and anyone whose hands take a daily battering. It's non-greasy, absorbs quickly, and doesn't leave a slippery residue — which matters when you're heading back to work straight after applying it.

 

How Does O'Keeffe's Working Hands Cream Work?

 

The formula targets the root cause of dry, cracked skin: a compromised skin barrier that loses moisture faster than it can retain it. Here's how it works:

  • Glycerin acts as a humectant, drawing water from the deeper layers of the skin and from the environment into the outer skin layer (the stratum corneum).
  • Allantoin promotes skin cell regeneration and helps soften rough, thickened skin, making it particularly useful for callused or cracked areas.
  • The cream creates a concentrated occlusive layer on the skin's surface, slowing transepidermal water loss (TEWL) — the process by which moisture evaporates through the skin.
  • With regular use, the skin barrier is gradually restored, reducing the frequency and severity of cracking and splitting.

The NHS notes that emollients — moisturising treatments that work by forming a protective film — are a cornerstone of managing dry skin conditions. O'Keeffe's Working Hands uses similar principles, though it is a cosmetic product rather than a licensed medicine.

 

Who Should Use O'Keeffe's Working Hands Cream?

 

This cream is designed for adults who experience persistent or severe hand dryness. It's not a medicated treatment, but it's well-suited to a wide range of people dealing with everyday skin barrier problems. You might find it particularly helpful if you:

  • Work in trades, construction, or agriculture where hands are exposed to harsh conditions
  • Wash your hands frequently — for example, in healthcare or food service roles
  • Experience dry, rough, or cracked hands during winter months
  • Have skin that feels tight, flaky, or uncomfortable after exposure to water or cleaning products

It is generally suitable for adults and older children, though if you have a diagnosed skin condition such as eczema or psoriasis, it's worth speaking to your pharmacist or GP before adding any new product to your routine. Our creams and ointments collection includes medicated options that may be more appropriate for certain skin conditions.

 

How Does O'Keeffe's Working Hands Compare to Other Hand Creams?

 

Feature O'Keeffe's Working Hands 60g Standard High-Street Hand Cream
Formulation focus Severely dry, cracked, split skin General daily moisturising
Fragrance-free Yes Often no
Non-greasy finish Yes — absorbs quickly Varies by product
Key active ingredients Glycerin, Allantoin Varies — often lighter humectants

 

Is O'Keeffe's Working Hands Cream Suitable for All Skin Types?

 

O'Keeffe's Working Hands cream is fragrance-free and does not contain common sensitisers, making it broadly suitable for most skin types including sensitive skin. However, as with any topical product, a small patch test on the inner wrist before first use is a sensible precaution — particularly if you have a history of contact dermatitis or allergic skin reactions. The NHS advises that people with known skin allergies should always check ingredient lists carefully before using new skincare products.

Store the tube below 25°C, away from direct sunlight and out of reach of children. The product does not require refrigeration.

This product is a cosmetic. If you have an underlying skin condition or are using other topical treatments, speak to your pharmacist before use.

O'Keeffe's Working Hands 60g Tube specifications
Treatment category Dry and cracked skin (cosmetic emollient)
Mechanism of action Humectant and occlusive barrier; reduces transepidermal water loss
Effective for Severely dry, rough, cracked, and split hands
Suitable for Adults and older children; fragrance-sensitive individuals
Active ingredients Glycerin, Allantoin
Pack size 60g tube
UK classification Cosmetic product (not a licensed medicine)
Preparation Cream
Route of administration Topical (applied to skin)

Specifications of O'Keeffe's Working Hands 60g Tube

 

What Is O'Keeffe's Working Hands and What Is It Used For?

 

O'Keeffe's Working Hands 60g is a concentrated, fragrance-free hand cream used to relieve and repair severely dry, cracked, and split skin on the hands. It is a cosmetic product — not a licensed medicine — and works by restoring moisture to the outer layers of the skin and helping to maintain the skin's natural barrier function. It is used by people whose hands are regularly exposed to conditions that strip away natural oils and moisture, such as cold air, frequent washing, or contact with harsh materials.

The NHS describes dry skin as a common condition that can cause the skin to feel tight, rough, or flaky, and recommends regular use of emollients to help manage it. O'Keeffe's Working Hands addresses these symptoms through its humectant and barrier-forming ingredients.

 

What Do You Need to Know Before Using O'Keeffe's Working Hands?

 

This product is generally well tolerated, but there are a few things worth knowing before you start using it.

Do not use this product if:

  • You are allergic to any of the listed ingredients — check the full ingredient list on the packaging before use
  • You have an open wound or severely broken skin that requires medical attention
  • You have been advised by a healthcare professional to avoid certain topical products

Warnings and precautions:

  • Avoid contact with the eyes — if contact occurs, rinse thoroughly with water
  • Discontinue use immediately if you develop a rash, redness, or worsening irritation
  • If you have a diagnosed skin condition such as eczema, psoriasis, or contact dermatitis, consult your GP or pharmacist before use
  • Keep out of reach of children
  • For external use only — do not ingest

Known drug or product interactions:

  • No clinically significant interactions with medicines are known for this cosmetic product
  • If you are using a prescribed topical treatment on your hands, apply O'Keeffe's at a different time of day and seek pharmacist advice

 

How Should You Use O'Keeffe's Working Hands?

 

Using this cream correctly makes a real difference to how quickly you see results. Consistency is key — applying it once and expecting overnight transformation isn't realistic, but twice-daily use over several days typically produces noticeable improvement.

  1. Wash and dry your hands thoroughly before applying
  2. Squeeze a small, pea-sized amount of cream onto your fingertips
  3. Rub the cream evenly across both hands, paying extra attention to cracked knuckles, fingertips, and any split areas
  4. Allow the cream to absorb fully before touching surfaces — it absorbs quickly and leaves a non-greasy finish
  5. Reapply after washing hands or whenever your skin feels dry or tight
Indication Age Group Amount Frequency
Severely dry, cracked hands Adults Small amount (pea-sized) At least twice daily
Maintenance / prevention Adults Small amount Once daily or as needed
Children (older) Under adult supervision Small amount As directed by pharmacist

If you're also managing foot dryness or cracking, you may find our foot care range useful alongside this product.

 

What Are the Possible Side Effects of O'Keeffe's Working Hands?

 

O'Keeffe's Working Hands is well tolerated by most people. Because it is fragrance-free and formulated without common sensitisers, adverse reactions are uncommon. That said, no topical product is entirely without risk, and it's worth knowing what to look out for.

Common side effects (may affect some users):

  • Mild, temporary stinging or tingling on application — particularly if skin is severely cracked or broken
  • Slight greasiness immediately after application before the cream fully absorbs

Less common side effects (rare):

  • Contact dermatitis — redness, itching, or a rash at the site of application
  • Allergic skin reaction — swelling, hives, or worsening skin irritation

If you notice any signs of an allergic reaction, stop using the product immediately and seek advice from your pharmacist or GP. The NHS advises that any new topical product causing persistent irritation should be discontinued and reviewed by a healthcare professional.

 

How Should You Store O'Keeffe's Working Hands?

 

Proper storage keeps the product effective for longer and ensures it remains safe to use. Follow these simple guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Keep the tube tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the tube
  • Do not freeze

If you're looking for other everyday health essentials, our first aid collection includes a range of products for minor skin concerns and everyday care.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy O'Keeffe's Working Hands cream online in the UK?

You can buy O'Keeffe's Working Hands 60g tube directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £6.40. Orders are dispatched quickly with tracked delivery options available. It's a convenient way to get the product without visiting a shop, especially if your hands are already sore and uncomfortable.

How does O'Keeffe's Working Hands cream work on dry skin?

The cream uses glycerin as a humectant to draw moisture into the outer layers of the skin, while allantoin helps to soften and regenerate rough or thickened skin cells. Together, these ingredients create a concentrated moisture barrier that slows transepidermal water loss — the process by which skin dries out. With regular use, the skin barrier is gradually restored, reducing cracking and splitting over time.

How do I use O'Keeffe's Working Hands step by step?

Start by washing and drying your hands thoroughly, then squeeze a small pea-sized amount onto your fingertips and rub it evenly across both hands. Pay particular attention to cracked knuckles, fingertips, and any split areas. Reapply after every handwash and at least twice daily for best results — consistency really does make the difference here.

How long does it take for O'Keeffe's Working Hands to show results?

Most people notice an improvement in skin texture and hydration within a few days of consistent twice-daily use. Severely cracked or split skin may take one to two weeks to fully repair, depending on how damaged the skin barrier is. Sticking to a regular routine — especially applying the cream before bed — tends to speed up recovery.

Is O'Keeffe's Working Hands cream safe for sensitive skin?

Yes, the formula is fragrance-free and does not contain common skin sensitisers, making it generally suitable for people with sensitive skin. It's always a good idea to do a small patch test on the inner wrist before applying it more widely, particularly if you have a history of allergic skin reactions. If redness, itching, or irritation develops, stop using it and speak to your pharmacist.

Can I use O'Keeffe's Working Hands cream every day?

Absolutely — it is designed for daily use and can be applied as often as needed throughout the day. Regular daily application is actually what makes it most effective, as the skin barrier needs consistent support to repair and maintain itself. Many users apply it morning, evening, and after each handwash as part of their routine.

Is O'Keeffe's Working Hands suitable for people with eczema?

While the cream is fragrance-free and may help relieve dryness associated with eczema, it is not a medicated eczema treatment and should not replace prescribed emollients or topical corticosteroids. If you have diagnosed eczema, speak to your GP or pharmacist before introducing any new product to your skincare routine. You can also explore our skin care range for products more specifically suited to eczema-prone skin.

What are the alternatives to O'Keeffe's Working Hands cream?

Alternatives for severely dry hands include Neutrogena Norwegian Formula Hand Cream, Aveeno Skin Relief Hand Cream, and various emollient-based products available on prescription for diagnosed skin conditions. O'Keeffe's Working Hands is specifically formulated for severely dry and cracked skin rather than general daily moisturising, which sets it apart from lighter everyday hand creams. If you need a medicated option, our creams and ointments collection includes a range of alternatives.

Can I use O'Keeffe's Working Hands if I'm pregnant or breastfeeding?

O'Keeffe's Working Hands is a topical cosmetic product applied to the hands, and its ingredients — glycerin and allantoin — are not known to pose a risk during pregnancy or breastfeeding when used as directed. However, as a precaution, it's always sensible to check with your midwife, GP, or pharmacist before introducing any new product during pregnancy. Avoid applying the cream to the nipple area if breastfeeding.

Does O'Keeffe's Working Hands cream leave a greasy residue?

No — one of the key features of this cream is its non-greasy, fast-absorbing formula, which means you can apply it and get back to work or daily tasks without waiting for it to dry. This makes it particularly practical for tradespeople, healthcare workers, and anyone who needs to use their hands immediately after application. A small amount goes a long way, so there's no need to apply a thick layer.

What ingredients are in O'Keeffe's Working Hands cream?

The key active ingredients are glycerin (a humectant that draws moisture into the skin) and allantoin (which promotes skin cell renewal and softens rough skin). The full ingredient list is printed on the product packaging and should be checked carefully if you have known allergies or sensitivities. The formula is fragrance-free and does not contain parabens as preservatives.

How long does a 60g tube of O'Keeffe's Working Hands last?

Because only a small, pea-sized amount is needed per application, a 60g tube typically lasts several weeks with twice-daily use — often four to six weeks for a single user. The concentrated formula means you don't need to use large quantities to get results, making it good value at £6.40 per tube. If you're sharing it with a partner or family member, you may go through it a little faster.

Can O'Keeffe's Working Hands be used on feet or other dry areas?

The product is specifically formulated and marketed for use on hands, but the emollient ingredients — glycerin and allantoin — are commonly used in foot creams too. If you want a product specifically designed for dry or cracked feet, our foot care collection includes options formulated for that purpose. Always check the product label before applying any hand cream to other body areas.

What is the best time to apply O'Keeffe's Working Hands cream?

Applying the cream at night before bed is particularly effective, as your hands are less likely to be washed or exposed to harsh conditions while you sleep, giving the ingredients more time to work. Morning application after your first handwash of the day is also recommended. Reapplying throughout the day — especially after washing hands — helps maintain the moisture barrier consistently.

Are there any known side effects of O'Keeffe's Working Hands cream?

Side effects are uncommon, but some people may experience mild, temporary stinging on application if their skin is severely cracked or broken. In rare cases, contact dermatitis — characterised by redness, itching, or a rash — can occur in individuals with sensitivities to specific ingredients. If you notice any persistent irritation or worsening of your skin, stop using the product and consult your pharmacist or GP.

How Should You Use O'Keeffe's Working Hands?

Using O'Keeffe's Working Hands correctly is straightforward, but a little technique goes a long way. The cream is concentrated, so you only need a small amount each time — using too much won't speed up results and will simply use up the tube faster.

What Is the Correct Dose of O'Keeffe's Working Hands?

There is no fixed medical dose for this cosmetic product, but using the right amount consistently is what delivers results. A pea-sized amount per application is sufficient for both hands — the formula is concentrated enough that more is not necessarily better.

When Is the Best Time to Use O'Keeffe's Working Hands?

Applying the cream at night before bed is particularly effective because your hands are less likely to be washed or exposed to harsh conditions while you sleep, giving the ingredients more uninterrupted time to work. Morning application after your first handwash of the day is equally important, as this helps establish the moisture barrier before your hands face the day's demands. Reapplying throughout the day — especially after washing hands — keeps the barrier consistently topped up.

How Long Can You Use O'Keeffe's Working Hands For?

O'Keeffe's Working Hands can be used as part of an ongoing daily routine for as long as needed — there is no maximum duration of use for this cosmetic product. Many people use it continuously through winter months when skin is most prone to drying out, then reduce to occasional use in warmer weather. If your skin does not improve after two to three weeks of consistent use, or if it worsens, speak to your pharmacist or GP to rule out an underlying skin condition that may need medical treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of O'Keeffe's Working Hands?

O'Keeffe's Working Hands is well tolerated by the vast majority of people who use it. Because it is fragrance-free and formulated without common sensitisers, adverse reactions are uncommon. That said, a small number of users do experience mild effects, particularly when first starting to use the cream on severely damaged skin.

  • Mild, temporary stinging or tingling on application — most likely if skin is severely cracked or broken
  • A slight tacky feeling immediately after application before the cream fully absorbs
  • Temporary whitening of the skin surface on first application, which fades as the cream absorbs

What Are the Less Common Side Effects of O'Keeffe's Working Hands?

Less common reactions are rare but worth being aware of, particularly if you have a history of skin sensitivities or allergic reactions to topical products. If you notice any of the following, stop using the cream and seek advice from your pharmacist.

  • Contact dermatitis — redness, itching, swelling, or a rash at the site of application
  • Worsening of existing skin dryness or irritation
  • Localised allergic reaction — hives, blistering, or peeling skin

What Are the Serious Side Effects of O'Keeffe's Working Hands?

Serious side effects from a topical cosmetic hand cream are extremely rare. However, if you experience signs of a systemic allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or widespread hives — stop using the product immediately and seek urgent medical attention. This type of reaction, known as anaphylaxis, is very uncommon with topical cosmetic products but is a medical emergency if it occurs. The NHS advises calling 999 if you suspect anaphylaxis.

What Should You Do If You Experience Side Effects?

For mild side effects such as temporary stinging, no action is usually needed — this often settles within a few days as the skin begins to repair. If you develop a rash, persistent redness, or worsening irritation, discontinue use and consult your pharmacist or GP. They can help determine whether the reaction is related to the cream or to an underlying skin condition that requires a different approach. Always mention any new topical products you've started using when discussing skin concerns with a healthcare professional.

Can O'Keeffe's Working Hands Interact With Other Products?

No clinically significant interactions with medicines are known for this cosmetic product. However, if you are using a prescribed topical treatment — such as a corticosteroid cream or an antibiotic ointment — on your hands, it is advisable to apply O'Keeffe's at a different time of day to avoid diluting or interfering with the prescribed product. Always inform your pharmacist of all topical products you are using, including cosmetics, so they can advise you appropriately.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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