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LMX4 Lidocaine 4% Cream - 30g

LMX4 Lidocaine 4% Cream - 30g

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LMX4 Lidocaine 4% Cream for Topical Anaesthesia

 

LMX4 is a topical anaesthetic containing 4% lidocaine that provides temporary numbing of the skin. This preservative-free formulation is designed for use before minor medical procedures, injections, or when temporary pain relief is needed for intact skin surfaces.

The cream comes in a 30g tube and is formulated to penetrate the skin effectively whilst maintaining patient comfort. Lidocaine 4% cream works by blocking nerve signals in the treated area, providing localised numbness that typically develops within 30-60 minutes of application.

 

How Lidocaine Works to Block Pain Signals

 

Lidocaine belongs to a group of medicines called local anaesthetics. It works by temporarily blocking sodium channels in nerve cell membranes, preventing the transmission of pain signals from the treated area to your brain.

When applied to intact skin, the cream penetrates the outer layers and reaches nerve endings beneath the surface. This creates a localised area of reduced sensation that can last for several hours, depending on the amount applied and individual response. You can find this product alongside other creams and ointments designed for topical application.

 

Who Can Benefit from Topical Anaesthetic Cream

 

LMX4 is suitable for adults and children who require temporary numbing of intact skin before minor procedures. Healthcare professionals often recommend topical anaesthetics to reduce discomfort during various treatments.

This numbing cream may be appropriate for:

  • Preparation before injections or blood tests
  • Minor dermatological procedures
  • Temporary relief from localised skin discomfort
  • Use before laser treatments or similar procedures

 

Why Choose a Preservative-Free Formula

 

LMX4's preservative-free formulation reduces the risk of skin irritation and allergic reactions that can sometimes occur with preserved topical preparations. This makes it particularly suitable for people with sensitive skin or those who have experienced reactions to other topical products.

The absence of preservatives also means the cream is less likely to cause contact dermatitis, making it a preferred choice for healthcare settings where patient comfort and safety are priorities.

 

Clinical Suitability and Professional Use

 

This local anaesthetic gel is commonly used in clinical settings due to its reliable numbing effect and good tolerability profile. The 4% concentration provides effective anaesthesia whilst remaining within safe parameters for topical use.

Store the cream at room temperature and keep the tube tightly closed when not in use. Do not use if the tube is damaged or if you notice any changes in the cream's appearance or consistency.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

 

How to Apply LMX4 Cream Correctly

Clean and dry the area of skin where you need numbing before application. Apply a thick layer of cream to intact skin only, ensuring complete coverage of the treatment area. The amount needed will depend on the size of the area being treated, but generally a layer approximately 2-3mm thick is recommended.

Cover the treated area with an occlusive dressing or plastic wrap if advised by your healthcare provider, as this can enhance the numbing effect. Leave the cream in place for the time recommended by your healthcare professional, typically 30-60 minutes before the planned procedure.

Timing and Duration of Treatment

The onset of numbing typically begins within 15-30 minutes of application, with maximum effect usually achieved after 45-60 minutes. The duration of anaesthesia can vary between individuals but generally lasts for 1-2 hours after removal of the cream.

Remove the cream thoroughly with a clean cloth or tissue before your procedure begins. Do not apply to broken, inflamed, or infected skin unless specifically directed by a healthcare professional. Always follow the specific instructions provided by your doctor or healthcare provider regarding application time and coverage area.

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Understanding Potential Side Effects

Like all medicines, LMX4 Lidocaine 4% Cream can have side effects, although not everyone will experience them. Most people tolerate topical lidocaine well, but you should be aware of possible reactions, especially if you're using other pain relief treatments.

The most commonly reported side effects are mild skin reactions at the application site, including temporary redness, slight swelling, or a burning sensation that usually resolves quickly after removal.

Possible side effects may include:

  • Skin redness or irritation at application site
  • Temporary burning or stinging sensation
  • Mild swelling of treated area
  • Skin blanching (temporary whitening)
  • Itching or rash
  • Allergic contact dermatitis
  • Temporary changes in skin sensation
  • Rare systemic effects if absorbed in large amounts

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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