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Hydrocortisone

Hydrocortisone

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  • ✔️ Relieves itch and redness from eczema and dermatitis
  • ✔️ Calms inflamed skin caused by insect bites and stings
  • ✔️ Contains hydrocortisone 1% — a clinically recognised mild steroid
  • ✔️ Suitable for adults and children aged 10 and over
  • ✔️ Available as cream, ointment, or gel for different skin types

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What Is Hydrocortisone Cream and How Can It Help?

 

If your skin is red, itchy, or inflamed, you are not alone. Millions of people in the UK deal with conditions like eczema, contact dermatitis, and insect bites every year. Hydrocortisone cream is one of the most widely used over-the-counter treatments for these kinds of skin flare-ups — and for good reason. It contains hydrocortisone 1%, a mild topical corticosteroid that works directly on the skin to calm inflammation and ease discomfort. You can browse our full range of creams and ointments to find the right product for your skin concern.

Available without a prescription at 1% strength, this product is suitable for adults and children aged 10 and over. It is indicated for short-term use only — typically no longer than seven days — and should be applied to the affected area as directed. At just £12.99, it offers a straightforward, clinically recognised option for managing mild to moderate skin irritation at home.

 

How Does Hydrocortisone Work on Inflamed Skin?

 

Hydrocortisone belongs to a class of medicines called corticosteroids. When applied topically, it works by binding to glucocorticoid receptors within skin cells, which then suppresses the production of pro-inflammatory mediators — including prostaglandins and cytokines. The result? Reduced redness, less swelling, and relief from that persistent itch.

  • Binds to intracellular glucocorticoid receptors in skin cells
  • Suppresses the release of inflammatory chemicals such as histamine and prostaglandins
  • Reduces capillary dilation, which decreases redness and localised swelling
  • Relieves itch by dampening the inflammatory response that triggers it

It does not treat the underlying cause of your skin condition — but it does give your skin a chance to settle, which is often exactly what you need during a flare-up.

 

Who Is Hydrocortisone Cream Suitable For?

 

This product is appropriate for a wide range of people dealing with mild inflammatory skin conditions. It is particularly useful if you experience occasional flare-ups rather than chronic, severe skin disease. That said, it is not suitable for everyone, so it is worth checking before you start.

  • Adults and children aged 10 and over with mild eczema or dermatitis
  • People with itchy skin reactions caused by insect bites or stings
  • Those experiencing contact dermatitis from allergens or irritants
  • Individuals with mild heat rash or nappy rash (in adults)

It is not recommended for use on infected skin, broken skin, or the face without medical advice. Children under 10 should only use it under the supervision of a doctor.

 

How Does Hydrocortisone Cream Compare to Other Topical Steroids?

 

Feature Hydrocortisone 1% (OTC) Clobetasone 0.05% (OTC)
Steroid potency Mild Moderate-mild
Available without prescription Yes Yes (Eumovate)
Suitable for children (10+) Yes Yes (12+)
Suitable for face No (without medical advice) No (without medical advice)

 

Is Hydrocortisone Cream Safe to Store at Home?

 

Yes — hydrocortisone cream is straightforward to store. Keep it below 25°C, away from direct sunlight and out of reach of children. Do not freeze it. Once opened, check the expiry date on the packaging and do not use it beyond that date. If you are managing a skin condition alongside other health concerns, our skin care collection includes a range of complementary products that may support your routine.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Hydrocortisone Cream specifications
Treatment category Topical corticosteroid / anti-inflammatory
Mechanism of action Suppresses inflammatory mediators via glucocorticoid receptor binding
Effective for Eczema, contact dermatitis, insect bites, mild skin inflammation
Suitable for Adults and children aged 10 and over
Active ingredient Hydrocortisone 1%
Strengths 1%
UK classification Pharmacy (P) medicine
Drug class Mild topical corticosteroid
Preparation Cream / Ointment / Gel
Route of administration Topical (applied to skin)

Specifications of Hydrocortisone Cream

 

What Is Hydrocortisone and What Is It Used For?

 

Hydrocortisone 1% cream is a mild topical corticosteroid used to relieve the symptoms of inflammatory skin conditions. It is licensed in the UK for the short-term treatment of mild eczema, contact dermatitis, insect bites and stings, and mild allergic skin reactions. It does not cure these conditions — rather, it reduces the inflammation and itch that make them so uncomfortable. The NHS recognises hydrocortisone as a first-line option for mild skin inflammation in adults and children aged 10 and over.

If you are also dealing with skin reactions linked to allergies, you may find our allergy and hay fever range helpful alongside topical treatment.

 

What Do You Need to Know Before Using Hydrocortisone?

 

Before applying this product, it is important to check whether it is appropriate for your situation. There are certain conditions and circumstances where hydrocortisone cream should not be used, or should only be used with caution.

Do not use hydrocortisone cream if you:

  • Are allergic to hydrocortisone or any other ingredient in the product
  • Have a skin infection (bacterial, fungal, or viral) at the site of application
  • Have acne, rosacea, or perioral dermatitis
  • Are applying it to broken or ulcerated skin
  • Are treating a child under 10 years old without a doctor's advice
  • Need to apply it to the face, groin, or underarms without medical guidance

Use with caution if you:

  • Are pregnant or breastfeeding — seek medical advice first
  • Have psoriasis — topical steroids can occasionally trigger a rebound flare
  • Are using other topical medicines on the same area of skin

Drug interactions:

  • No significant interactions are known for topical hydrocortisone at OTC strengths when used as directed
  • Avoid using alongside other topical corticosteroids on the same area without medical advice

 

How Should You Use Hydrocortisone Cream Correctly?

 

Using hydrocortisone correctly makes a real difference to how well it works — and helps you avoid unnecessary side effects. Always follow the instructions on the packaging or as directed by your pharmacist.

  1. Wash and dry the affected area gently before applying
  2. Squeeze a small amount of cream onto your fingertip
  3. Apply a thin layer to the affected skin only — do not spread beyond the inflamed area
  4. Rub in gently until absorbed
  5. Wash your hands thoroughly after application (unless treating your hands)
  6. Do not cover the treated area with an airtight dressing unless advised by a doctor
Indication Age Group Dose Frequency
Mild eczema / dermatitis Adults & children 10+ Thin layer to affected area Once or twice daily
Insect bites / stings Adults & children 10+ Thin layer to affected area Once or twice daily
Contact dermatitis Adults & children 10+ Thin layer to affected area Once or twice daily
Children under 10 Under 10 Only under medical supervision

 

What Are the Possible Side Effects of Hydrocortisone?

 

Like all medicines, hydrocortisone cream can cause side effects, although not everyone experiences them. Most side effects are related to prolonged or incorrect use rather than short-term application as directed.

Common side effects:

  • Mild burning, stinging, or itching at the application site
  • Skin dryness or irritation
  • Temporary redness immediately after application

Less common side effects (usually associated with prolonged use):

  • Skin thinning (atrophy)
  • Stretch marks (striae)
  • Changes in skin pigmentation
  • Increased hair growth at the application site
  • Worsening of skin infections if applied to infected skin

If you notice any unexpected skin changes or your condition worsens, stop using the product and speak to your pharmacist or GP. You can also explore our first aid range for additional skin support products.

 

How Should You Store Hydrocortisone Cream?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze
  • Keep the cap tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy hydrocortisone cream online in the UK?

You can buy hydrocortisone cream online from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available at 1% strength as a Pharmacy (P) medicine without a prescription for adults and children aged 10 and over. Simply add it to your basket and complete a short health questionnaire to confirm suitability.

How does hydrocortisone cream work on itchy skin?

Hydrocortisone is a mild corticosteroid that binds to glucocorticoid receptors in skin cells, suppressing the release of inflammatory chemicals like prostaglandins and histamine. This reduces redness, swelling, and the itch response. It works locally on the skin rather than throughout the body, which is why it is considered safe for short-term OTC use.

How do I apply hydrocortisone cream step by step?

Clean and dry the affected area first, then apply a thin layer of cream using your fingertip and rub it in gently. Wash your hands after application unless you are treating your hands. Apply once or twice daily as directed — do not apply more frequently than recommended, as this does not improve results and increases the risk of side effects.

What is the correct dose of hydrocortisone cream for adults?

For adults, apply a thin layer of hydrocortisone 1% cream to the affected area once or twice daily. Use the smallest amount needed to cover the inflamed skin. Do not apply more than twice a day, and do not use for longer than seven days without speaking to a pharmacist or doctor.

How long can I use hydrocortisone cream for?

OTC hydrocortisone cream should be used for a maximum of seven days without medical review. Using it for longer than this — especially on the face or skin folds — increases the risk of skin thinning and other side effects. If your symptoms have not improved after a week, speak to your GP or pharmacist.

What are the side effects of hydrocortisone cream?

Common side effects include mild burning, stinging, or temporary redness at the application site. With prolonged use, skin thinning, stretch marks, and changes in pigmentation can occur. These effects are more likely if you apply it to delicate areas like the face or skin folds, or if you use it for longer than recommended.

Can I use hydrocortisone cream on my face?

You should not apply hydrocortisone cream to your face without specific advice from a doctor. Facial skin is thinner and more sensitive, making it more vulnerable to side effects such as skin thinning and rosacea-like reactions. If you have a facial skin condition, speak to your GP who may recommend an alternative treatment.

Is hydrocortisone cream safe to use during pregnancy?

Small amounts of hydrocortisone cream applied to limited areas of skin are generally considered low risk during pregnancy, but you should always speak to your doctor or midwife before using any medicine when pregnant. Avoid applying it to large areas of skin or under occlusive dressings during pregnancy. Your healthcare provider can advise on the safest approach for your situation.

Who should not use hydrocortisone cream?

Hydrocortisone cream is not suitable for people with skin infections (bacterial, fungal, or viral), acne, rosacea, or perioral dermatitis at the site of application. It should also not be used on broken or ulcerated skin, or by children under 10 without a doctor's supervision. If you are unsure whether it is right for you, speak to a pharmacist before purchasing.

What is the difference between hydrocortisone cream and hydrocortisone ointment?

Hydrocortisone cream is water-based, absorbs more readily, and is better suited to moist, weeping, or inflamed skin. Ointment is greasier and more occlusive, making it more effective for dry, thickened, or scaly patches of skin. Both contain the same active ingredient at the same strength — the choice depends on your skin type and the nature of your condition.

Can I use hydrocortisone cream for insect bites?

Yes — hydrocortisone cream is a recognised treatment for the itch and inflammation caused by insect bites and stings. The NHS recommends applying a mild steroid cream like hydrocortisone to reduce swelling and relieve itching. Apply a thin layer to the bite area once or twice daily for up to seven days. You can also explore our first aid range for additional bite and sting relief options.

What are the alternatives to hydrocortisone cream?

Alternatives include other mild topical corticosteroids such as clobetasone butyrate 0.05% (Eumovate), which is slightly stronger and available OTC for eczema. Non-steroidal options include emollients and moisturisers for dry skin, or antihistamine creams for insect bites. For more persistent or severe skin conditions, a GP may prescribe a stronger topical steroid. Browse our skin care collection for a wider range of options.

What happens if I miss an application of hydrocortisone cream?

If you forget to apply hydrocortisone cream at your usual time, simply apply it as soon as you remember — unless it is nearly time for your next application, in which case skip the missed dose. Do not apply a double amount to make up for a missed application. Consistency helps, but missing one application is unlikely to significantly affect your results.

Can children use hydrocortisone cream?

Children aged 10 and over can use OTC hydrocortisone cream 1% for short-term treatment of mild eczema, dermatitis, or insect bites. Children under 10 should only use it under the direct supervision of a doctor. Always apply the smallest effective amount and avoid using it on large areas of a child's skin or for longer than seven days without medical advice.

What does the latest evidence say about topical hydrocortisone for eczema?

Current NHS and NICE guidance continues to support mild topical corticosteroids like hydrocortisone 1% as a first-line treatment for mild eczema flare-ups in adults and children. Evidence consistently shows that short-term use is safe and effective when applied correctly. Long-term or excessive use remains the main concern, which is why the seven-day OTC limit exists.

How Should You Use Hydrocortisone Cream?

Applying hydrocortisone cream correctly is important — not just for effectiveness, but to minimise the risk of side effects. Always use the smallest amount that covers the affected area, and avoid applying it to healthy surrounding skin.

Avoid getting the cream in your eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water.

What Is the Correct Dose of Hydrocortisone Cream?

The dose depends on the condition being treated and the age of the person using it. Always follow the instructions on the packaging or as directed by your pharmacist. Using more than the recommended amount will not make it work faster — it only increases the risk of side effects.

When Is the Best Time to Use Hydrocortisone Cream?

There is no single "best" time of day to apply hydrocortisone cream — consistency matters more than timing. Many people find it easiest to apply once in the morning and once in the evening as part of their skincare routine. If you are using an emollient or moisturiser alongside it, apply the emollient first and wait at least 30 minutes before applying hydrocortisone, so the steroid can penetrate the skin effectively rather than being diluted.

Avoid applying immediately before bathing or swimming, as this will wash the product away before it has had time to work.

How Long Can You Use Hydrocortisone Cream For?

OTC hydrocortisone cream 1% should not be used for more than seven consecutive days without seeking medical advice. Short-term use within this window is considered safe and effective for most people. If your symptoms persist beyond seven days, worsen, or return frequently, this may indicate that a different treatment or a stronger prescription product is needed — speak to your GP or pharmacist.

Prolonged use, particularly on delicate areas such as the face, groin, or underarms, significantly increases the risk of skin thinning and other steroid-related side effects. Always use the minimum effective amount for the shortest time necessary.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Hydrocortisone Cream?

Applying hydrocortisone cream correctly is important — not just for effectiveness, but to minimise the risk of side effects. Always use the smallest amount that covers the affected area, and avoid applying it to healthy surrounding skin.

Avoid getting the cream in your eyes, mouth, or nose. If accidental contact occurs, rinse thoroughly with water.

What Is the Correct Dose of Hydrocortisone Cream?

The dose depends on the condition being treated and the age of the person using it. Always follow the instructions on the packaging or as directed by your pharmacist. Using more than the recommended amount will not make it work faster — it only increases the risk of side effects.

When Is the Best Time to Use Hydrocortisone Cream?

There is no single "best" time of day to apply hydrocortisone cream — consistency matters more than timing. Many people find it easiest to apply once in the morning and once in the evening as part of their skincare routine. If you are using an emollient or moisturiser alongside it, apply the emollient first and wait at least 30 minutes before applying hydrocortisone, so the steroid can penetrate the skin effectively rather than being diluted.

Avoid applying immediately before bathing or swimming, as this will wash the product away before it has had time to work.

How Long Can You Use Hydrocortisone Cream For?

OTC hydrocortisone cream 1% should not be used for more than seven consecutive days without seeking medical advice. Short-term use within this window is considered safe and effective for most people. If your symptoms persist beyond seven days, worsen, or return frequently, this may indicate that a different treatment or a stronger prescription product is needed — speak to your GP or pharmacist.

Prolonged use, particularly on delicate areas such as the face, groin, or underarms, significantly increases the risk of skin thinning and other steroid-related side effects. Always use the minimum effective amount for the shortest time necessary.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Hydrocortisone Cream?

Most people who use hydrocortisone cream as directed for short periods do not experience significant side effects. However, some mild local reactions can occur, particularly when you first start using it.

  • Mild burning or stinging sensation at the application site
  • Temporary redness or warmth of the skin
  • Itching or skin irritation immediately after application
  • Dryness or flaking of the treated skin

These effects are usually short-lived and tend to settle as your skin adjusts. If they persist or feel severe, stop using the product and speak to your pharmacist.

What Are the Less Common Side Effects of Hydrocortisone Cream?

Less common side effects are more likely to occur with prolonged use, application to large areas of skin, or use under occlusive dressings. They are rarely seen with short-term OTC use when the product is applied correctly.

  • Skin thinning (atrophy) — particularly with extended use
  • Stretch marks (striae), especially in skin folds
  • Changes in skin pigmentation (lightening or darkening)
  • Increased hair growth (hypertrichosis) at the application site
  • Perioral dermatitis — a rash around the mouth if applied to the face
  • Worsening of an existing skin infection if applied to infected skin

What Are the Serious Side Effects of Hydrocortisone Cream?

Serious systemic side effects from OTC hydrocortisone cream 1% are extremely rare when used as directed. However, if very large areas of skin are treated for prolonged periods — particularly in children — there is a theoretical risk of adrenal suppression, where the body's natural cortisol production is affected. This is not a concern with normal short-term use on small areas.

Seek urgent medical attention if you notice signs of a severe allergic reaction, including swelling of the face, lips, or throat, difficulty breathing, or a widespread skin rash developing rapidly after application.

What Should You Do If You Experience Side Effects?

If you experience mild local reactions such as stinging or temporary redness, these often resolve on their own. Try applying a slightly smaller amount and ensure you are not using the product more frequently than twice daily. If side effects persist, worsen, or you develop signs of a skin infection (increased pain, pus, or spreading redness), stop using the cream and consult your pharmacist or GP promptly.

Do not attempt to self-treat a skin infection with hydrocortisone — it can mask the signs of infection and make it worse.

Can Hydrocortisone Cream Interact With Other Medicines?

Topical hydrocortisone at 1% OTC strength has no significant known interactions with oral medicines when used as directed on small areas of skin. However, you should avoid using other topical corticosteroids on the same area of skin at the same time without medical advice, as this can increase the total steroid load on the skin. If you are using any prescription topical medicines, always check with your pharmacist before adding hydrocortisone cream to your routine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Frequently Asked Question


Hydrocortisone treats inflammation and itching caused by eczema, dermatitis, allergic skin reactions, insect bites, and mild rashes. It doesn't cure the cause of the problem, but it calms the flare-up so your skin can heal more comfortably.


You can, but only carefully. Facial skin is thinner and absorbs steroids more easily. Use a very small amount, for no longer than 3–5 days, and avoid the eye area completely. It’s best to confirm with a pharmacist before using it on your face.


No — it only reduces inflammation. If the skin is infected (ringworm, impetigo, athlete’s foot, etc.), hydrocortisone alone can actually make symptoms worse. In those cases, a doctor may prescribe a combination treatment with an antifungal or antibiotic.


Many people feel relief from itching within minutes, while redness and swelling usually start improving within 24–48 hours. Full improvement can take a few days depending on how irritated the skin was initially.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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What skin problems does Hydrocortisone Cream treat?


Hydrocortisone treats inflammation and itching caused by eczema, dermatitis, allergic skin reactions, insect bites, and mild rashes. It doesn't cure the cause of the problem, but it calms the flare-up so your skin can heal more comfortably.

Can I use Hydrocortisone on my face?


You can, but only carefully. Facial skin is thinner and absorbs steroids more easily. Use a very small amount, for no longer than 3–5 days, and avoid the eye area completely. It’s best to confirm with a pharmacist before using it on your face.

Does Hydrocortisone treat fungal or bacterial infections?


No — it only reduces inflammation. If the skin is infected (ringworm, impetigo, athlete’s foot, etc.), hydrocortisone alone can actually make symptoms worse. In those cases, a doctor may prescribe a combination treatment with an antifungal or antibiotic.

How long does it take for Hydrocortisone Cream to work?


Many people feel relief from itching within minutes, while redness and swelling usually start improving within 24–48 hours. Full improvement can take a few days depending on how irritated the skin was initially.