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Hirudoid Gel 50g - Soothing Relief For Inflammation Of The Veins

Hirudoid Gel 50g - Soothing Relief For Inflammation Of The Veins

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  • ✔️ Relieves superficial vein inflammation and tenderness effectively
  • ✔️ Helps disperse bruising and haematomas with regular use
  • ✔️ Contains mucopolysaccharide polysulphate with mild anticoagulant action
  • ✔️ Suitable for adults and children over five years old
  • ✔️ Convenient 50g tube for targeted topical application

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What Is Hirudoid Gel and How Does It Help Vein Inflammation?

 

If you've ever dealt with a painful, tender lump along a vein — perhaps after a cannula, a knock, or a period of prolonged standing — you'll know how uncomfortable it can be. Hirudoid gel is a well-established, over-the-counter topical treatment used to relieve the pain, swelling, and tenderness associated with superficial vein inflammation, bruising, and haematomas. It has been used in clinical practice for decades and remains a trusted option for people seeking targeted, localised relief without needing a prescription.

The active ingredient is mucopolysaccharide polysulphate 0.3%, a compound with both anti-inflammatory and mild anticoagulant properties. It's applied directly to the skin over the affected area, making it a convenient choice for conditions that are localised rather than systemic. You can browse our wider range of creams and ointments if you're looking for other topical treatments alongside this one.

 

How Does Hirudoid Gel Work on Inflamed Veins?

 

Mucopolysaccharide polysulphate works through several complementary mechanisms when applied to the skin. It penetrates the superficial layers of the dermis and acts locally on the affected tissue. Here's what happens:

  • It inhibits inflammatory mediators, reducing localised swelling and tenderness around the affected vein.
  • It has mild anticoagulant activity, which helps to prevent further clot formation in superficial vessels.
  • It promotes the resorption of haematomas and bruising by improving local blood and lymphatic circulation.
  • It softens and breaks down fibrous tissue that can form around a bruise or inflamed vein over time.

These combined effects make it particularly useful for conditions like superficial thrombophlebitis — where a vein near the skin surface becomes inflamed, often forming a palpable, cord-like tender area. It's worth noting that this gel treats superficial veins only; deep vein thrombosis (DVT) requires urgent medical assessment and is not managed with topical treatments.

 

Who Should Use Hirudoid Gel and Is It Right for You?

 

Hirudoid gel is suitable for adults and children over 5 years of age. It's particularly helpful for people who experience recurring superficial vein problems, those who bruise easily, or anyone recovering from minor trauma to soft tissue. It's available without a prescription, making it accessible for self-care at home.

It may be appropriate for you if you have:

  • Superficial thrombophlebitis (inflammation of a vein near the skin surface)
  • Bruising or haematomas following injury or medical procedures such as cannulation
  • Localised swelling and tenderness from soft tissue trauma
  • Post-injection bruising or inflammation

It is not suitable for use on broken, infected, or ulcerated skin. People with known hypersensitivity to any of the ingredients should avoid it. If you're unsure whether this product is right for your situation, speak to a pharmacist before use.

 

How Does Hirudoid Gel Compare to Alternative Topical Treatments?

 

Feature Hirudoid Gel 50g Ibuprofen Gel (e.g. Ibugel)
Active ingredient Mucopolysaccharide polysulphate 0.3% Ibuprofen 5% or 10%
Primary use Vein inflammation, bruising, haematomas Muscle and joint pain, sprains
Anticoagulant effect Yes (mild, localised) No
Suitable for post-cannula bruising Yes Not specifically indicated

 

Is Hirudoid Gel Suitable for Long-Term Use and How Should It Be Stored?

 

Hirudoid gel is generally intended for short-term use — typically up to two weeks. If your symptoms haven't improved after this time, or if they worsen, you should consult your GP. Prolonged use without medical review isn't recommended. For those managing recurring vein-related discomfort, it's worth discussing an ongoing management plan with your doctor rather than relying solely on topical treatment.

Store the gel below 25°C, away from direct sunlight and out of the reach of children. Do not use after the expiry date printed on the tube. If you're also managing pain from other causes, our pain relief collection includes a range of options that may complement your care.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Hirudoid Gel 50g specifications
Treatment category Vein inflammation, bruising, haematomas
Active ingredient Mucopolysaccharide polysulphate 0.3%
Mechanism of action Anti-inflammatory and mild anticoagulant activity; promotes resorption of bruising
Suitable for Adults and children over 5 years
Pack size 50g tube
Strength 0.3% w/w mucopolysaccharide polysulphate
UK classification P (Pharmacy medicine)
Drug class Topical anticoagulant / anti-inflammatory
Preparation Gel
Route of administration Topical (cutaneous)

Specifications of Hirudoid Gel 50g

 

What Is Hirudoid Gel and What Is It Used For?

 

Hirudoid Gel 50g is a topical medicine containing mucopolysaccharide polysulphate 0.3% as its active ingredient. It belongs to a class of medicines known as topical anticoagulants and anti-inflammatory agents. It is used to treat conditions affecting the superficial veins and surrounding soft tissue, including superficial thrombophlebitis, bruising, haematomas, and localised swelling following trauma or medical procedures.

Superficial thrombophlebitis occurs when a vein close to the surface of the skin becomes inflamed, often forming a tender, red, cord-like area. According to the NHS, this condition is usually not serious but can be painful and uncomfortable. Hirudoid gel helps to reduce this inflammation and ease associated discomfort when applied regularly to the affected area.

 

What Do You Need to Know Before Using Hirudoid Gel?

 

Before applying this gel, read the following carefully. There are certain situations where you should not use it, and others where caution is needed.

Do not use Hirudoid Gel if you:

  • Are allergic to mucopolysaccharide polysulphate or any other ingredient in the gel
  • Have broken, infected, or ulcerated skin at the application site
  • Have an open wound or raw skin in the area to be treated
  • Are applying it near the eyes or mucous membranes

Use with caution and speak to a pharmacist or GP if you:

  • Are pregnant or breastfeeding — safety data for topical use in pregnancy is limited
  • Are giving this to a child under 5 years of age
  • Have a known bleeding disorder or are taking anticoagulant medicines
  • Have symptoms that could suggest a deep vein thrombosis (DVT), such as significant leg swelling, warmth, or redness — seek urgent medical advice in this case

Known drug interactions:

  • No significant systemic drug interactions are expected at topical doses
  • Caution is advised if you are using other topical anticoagulants on the same area

 

How Should You Use Hirudoid Gel Correctly?

 

Always use this medicine exactly as described in the patient information leaflet or as directed by your pharmacist. Do not apply more than recommended, and do not use it on areas of skin that are not affected.

  1. Wash and dry your hands thoroughly before use.
  2. Squeeze a small amount of gel (approximately 3–5 cm) onto your fingertip.
  3. Apply gently to the affected area and massage in using light, circular movements.
  4. Allow the gel to absorb fully before covering the area with clothing or a dressing.
  5. Wash your hands again after application.
  6. Repeat two to three times daily, or as directed by your pharmacist.
Indication Age Group Dose Frequency
Superficial thrombophlebitis Adults 3–5 cm strip of gel 2–3 times daily
Bruising / haematoma Adults 3–5 cm strip of gel 2–3 times daily
Soft tissue trauma Children over 5 years Smaller amount as appropriate 2 times daily

 

What Are the Possible Side Effects of Hirudoid Gel?

 

Like all medicines, Hirudoid Gel can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the area of application. If you experience any severe or unexpected reaction, stop using the gel and seek medical advice promptly.

Common side effects:

  • Mild skin irritation at the application site
  • Temporary redness or warmth of the skin
  • Slight tingling sensation after application

Less common side effects:

  • Contact dermatitis (allergic skin reaction)
  • Localised rash or itching
  • Skin dryness with prolonged use

If you notice signs of a more serious allergic reaction — such as widespread rash, difficulty breathing, or significant swelling — stop use immediately and seek emergency medical attention. You can find further guidance on managing skin reactions on the NHS website. If you're also exploring other topical options for skin concerns, our skin care collection may be of interest.

 

How Should You Store Hirudoid Gel?

 

Correct storage helps to maintain the effectiveness and safety of the gel throughout its shelf life.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the tube tightly closed when not in use
  • Store out of the sight and reach of children
  • Do not use after the expiry date printed on the tube or carton
  • Do not freeze
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy

If you have any questions about storage or whether your gel is still safe to use, speak to your pharmacist. You can also find general first aid and wound care products in our first aid collection.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Hirudoid Gel online in the UK?

You can buy Hirudoid Gel 50g online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £6.69. It is a Pharmacy (P) medicine, so it is available without a prescription but should be purchased from a registered pharmacy. It may also be available from some high street pharmacies, though online ordering offers the convenience of home delivery.

How does Hirudoid Gel work in the body?

Hirudoid Gel contains mucopolysaccharide polysulphate 0.3%, which penetrates the skin and acts locally on inflamed superficial veins and bruised tissue. It reduces inflammation, has a mild anticoagulant effect to discourage further clot formation, and helps the body reabsorb bruising and haematomas more quickly. It does not enter the bloodstream in significant amounts when used as directed.

How do I apply Hirudoid Gel step by step?

Wash your hands, then squeeze approximately 3–5 cm of gel onto your fingertip and gently massage it into the affected area using light circular movements. Allow it to absorb fully before covering with clothing. Apply two to three times daily and always wash your hands after use.

How long does Hirudoid Gel take to work?

Many people notice a reduction in tenderness and swelling within a few days of consistent use. Full improvement in bruising or vein inflammation typically takes one to two weeks, depending on the severity of the condition. If there is no improvement after two weeks, consult your GP or pharmacist.

What is the correct dose of Hirudoid Gel for adults?

For adults, apply a 3–5 cm strip of gel to the affected area two to three times daily. Do not apply more than this amount in a single application, and do not use it on large areas of the body without medical advice. Always follow the instructions in the patient information leaflet.

Can children use Hirudoid Gel?

Hirudoid Gel can be used in children over 5 years of age, using a smaller amount than the adult dose. It should not be used in children under 5 without specific medical advice. Always supervise application in children and keep the tube out of their reach when not in use.

Is Hirudoid Gel safe to use during pregnancy?

There is limited safety data on the use of topical mucopolysaccharide polysulphate during pregnancy. If you are pregnant or breastfeeding, you should speak to your doctor or pharmacist before using Hirudoid Gel. They can advise whether the potential benefit outweighs any theoretical risk in your specific situation.

What are the side effects of Hirudoid Gel?

Side effects are uncommon but may include mild skin irritation, temporary redness, or a tingling sensation at the application site. Less commonly, some people may experience a localised allergic skin reaction such as a rash or itching. Stop use and consult a pharmacist if any irritation persists or worsens.

Can I use Hirudoid Gel on broken or infected skin?

No — Hirudoid Gel must not be applied to broken, open, infected, or ulcerated skin. It is designed for use on intact skin only. Applying it to damaged skin could cause irritation or allow the active ingredient to be absorbed in unintended amounts.

How long can I use Hirudoid Gel for?

Hirudoid Gel is intended for short-term use, generally up to two weeks. If your symptoms have not resolved within this time, or if they worsen at any point, you should seek advice from your GP. Long-term use without medical supervision is not recommended.

What happens if I miss an application of Hirudoid Gel?

If you forget to apply the gel at your usual time, apply it as soon as you remember. However, if it is nearly time for your next application, simply skip the missed one and continue as normal. Do not apply a double amount to make up for a missed dose.

Does Hirudoid Gel interact with other medicines?

No significant systemic drug interactions are expected when Hirudoid Gel is used topically as directed, as very little active ingredient is absorbed into the bloodstream. However, if you are taking oral anticoagulants such as warfarin, or using other topical anticoagulant products on the same area, speak to your pharmacist before use as a precaution.

What are the alternatives to Hirudoid Gel for vein inflammation?

Alternatives for superficial thrombophlebitis and bruising include topical ibuprofen gels for their anti-inflammatory effect, though these are not specifically indicated for vein inflammation. Compression stockings may also help with superficial vein discomfort. For broader pain relief options, you can explore our full range online. Always consult a pharmacist or GP to find the most appropriate treatment for your specific condition.

Can Hirudoid Gel be used after a cannula or blood test bruise?

Yes — Hirudoid Gel is commonly used to help resolve bruising and localised inflammation following cannulation or venepuncture. Apply it gently to the bruised area two to three times daily, ensuring the skin is intact and the puncture site has fully closed before use. It can help speed up the resorption of the bruise and reduce tenderness.

What is the latest research on mucopolysaccharide polysulphate gels?

Mucopolysaccharide polysulphate has been used clinically for several decades, and its anti-inflammatory and anticoagulant properties in superficial vein conditions are well documented in the medical literature. Research continues to support its use for superficial thrombophlebitis and bruising management. If you'd like to explore other evidence-based topical treatments, our creams and ointments collection includes a range of clinically recognised options.

How Should You Use Hirudoid Gel?

Hirudoid Gel is applied directly to the skin over the affected area. Always wash your hands before and after application, and make sure the skin is clean and dry before you begin. Never apply the gel to broken, infected, or ulcerated skin.

What Is the Correct Dose of Hirudoid Gel?

The dose varies depending on the age of the person using it and the condition being treated. Always follow the instructions provided in the patient information leaflet or as directed by your pharmacist. Do not apply more than the recommended amount.

When Is the Best Time to Use Hirudoid Gel?

There is no single fixed time of day that is clinically required for Hirudoid Gel. However, spacing your applications evenly throughout the day — for example morning, midday, and evening — helps to maintain a consistent anti-inflammatory effect on the affected tissue. Applying it after a gentle wash of the area can also help the gel absorb more effectively.

Try to build application into your daily routine so you don't miss doses. Consistency matters more than the exact time of day when it comes to getting the most from this treatment.

How Long Can You Use Hirudoid Gel For?

Hirudoid Gel is intended for short-term use only, typically for a period of up to two weeks. Most people see a noticeable improvement in bruising, tenderness, and vein inflammation within this timeframe when the gel is applied consistently as directed.

If your symptoms have not improved after two weeks, or if they worsen at any point during treatment, stop using the gel and consult your GP. Do not continue using it beyond the recommended period without medical advice, as this is not a long-term maintenance treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Based on 3 reviews
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33%
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C
Colin chapman

This gel helps to lessen the redness of my skin but does not improve the condition that causes it. Quite Useless for reducing bruises .

K
Karen White

Excellent value and speedy delivery.
Will definitely use again.

M
Max
Happy customer

Product as stated. Quick ordering and delivery

What Are the Most Common Side Effects of Hirudoid Gel?

Hirudoid Gel is generally well tolerated when used as directed. Most people do not experience any side effects. However, as with all medicines applied to the skin, some localised reactions can occur, particularly in people with sensitive skin.

  • Mild skin irritation at the application site
  • Temporary redness or warmth of the skin
  • Slight tingling or stinging sensation after application

What Are the Less Common Side Effects of Hirudoid Gel?

Less commonly, some people may develop a more noticeable skin reaction. These reactions are usually localised to the area where the gel has been applied and tend to resolve once you stop using the product.

  • Contact dermatitis — an allergic skin reaction causing redness, itching, and inflammation
  • Localised rash or hives
  • Skin dryness or peeling with prolonged use
  • Increased sensitivity of the skin at the application site

What Are the Serious Side Effects of Hirudoid Gel?

Serious side effects from topical Hirudoid Gel are rare. Because very little of the active ingredient is absorbed into the bloodstream when used correctly, systemic effects are not expected. However, if you develop signs of a severe allergic reaction — such as widespread rash, swelling of the face or throat, difficulty breathing, or dizziness — stop using the gel immediately and seek emergency medical attention by calling 999 or going to your nearest A&E.

You should also seek urgent medical advice if the area you are treating becomes significantly more swollen, hot, or painful, as this could indicate an infection or a more serious vascular condition such as deep vein thrombosis (DVT), which requires prompt assessment.

What Should You Do If You Experience Side Effects of Hirudoid Gel?

If you notice mild irritation or redness that does not settle within a day or two of starting treatment, stop applying the gel and speak to your pharmacist. They can advise whether you should continue, switch to an alternative product, or seek further medical review.

You can also report suspected side effects directly to the MHRA through the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps to monitor the safety of medicines used in the UK and contributes to ongoing pharmacovigilance.

Can Hirudoid Gel Interact With Other Medicines?

At the doses used topically, Hirudoid Gel is not expected to cause significant interactions with other medicines. Systemic absorption is minimal when the gel is applied to intact skin as directed. That said, if you are using other topical anticoagulant products on the same area, or if you are taking oral anticoagulants such as warfarin or direct oral anticoagulants (DOACs), it is sensible to inform your pharmacist before starting treatment. They can review your full medication list and advise accordingly.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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