Skip to product information
1 of 1

  • Images are for illustration purposes only

Eucerin Dermo PURIFYER Oil Control Adjunctive Soothing Cream-50ml

Eucerin Dermo PURIFYER Oil Control Adjunctive Soothing Cream-50ml

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Controls excess sebum production with L-Carnitine for less shine
  • ✔️ Soothes acne-related redness with anti-inflammatory Licochalcone A
  • ✔️ Non-comedogenic formula won't block pores or worsen breakouts
  • ✔️ Dermatologically tested for oily, sensitive, and acne-prone skin
  • ✔️ Adjunctive formula supports prescription acne treatments effectively

Price Checker

Regular price £9.38
Sale price £9.38
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

Is Eucerin Dermo Purifyer the Right Oily Skin Cream for Acne?

 

Dealing with oily, acne-prone skin can feel like a constant battle. You cleanse, you treat, and yet that unwanted shine returns by midday. The Eucerin Dermo Purifyer Oil Control Adjunctive Soothing Cream 50ml is specifically formulated to sit alongside your existing acne treatment — helping to calm irritated skin, regulate excess sebum, and restore a more comfortable, matte finish. If you're looking for a reliable oily skin cream for acne that won't clog your pores or aggravate sensitivity, this product is worth considering. You can explore a wider range of options in our skin care collection.

Acne is one of the most common skin conditions in the UK, affecting up to 95% of people aged 11–30 at some point, according to the NHS. Managing it effectively often requires more than just a spot treatment — the skin barrier needs support too. That's where an adjunctive moisturiser like this one plays a meaningful role.

 

How Does Eucerin Dermo Purifyer Oil Control Cream Work?

 

The cream works through two key active ingredients that target the root causes of oily, acne-prone skin discomfort:

  • Licochalcone A — a natural extract derived from liquorice root with documented anti-inflammatory properties. It helps to reduce redness and calm the skin irritation that often accompanies acne.
  • L-Carnitine — an amino acid derivative that actively regulates sebaceous gland activity, reducing the amount of sebum (oil) the skin produces. This directly addresses the shine and greasiness associated with oily skin types.
  • The non-comedogenic formula means it is specifically designed not to block pores — a critical consideration for anyone managing acne.
  • The lightweight texture absorbs quickly, making it suitable for use under makeup or SPF products.

Together, these ingredients work to soothe, balance, and protect the skin without adding unnecessary heaviness or occlusion.

 

Who Should Use Eucerin Dermo Purifyer Soothing Cream?

 

This cream is designed as an adjunctive product — meaning it works best alongside a prescribed or recommended acne treatment rather than as a standalone cure. It is particularly well-suited to:

  • Teenagers and adults with oily or combination skin prone to breakouts
  • People currently using topical acne treatments (such as retinoids or antibiotics) who need a gentle, non-irritating moisturiser
  • Those with sensitive skin who find many moisturisers too heavy or pore-blocking
  • Anyone seeking to reduce facial shine and improve skin comfort day-to-day

It is not intended to replace medical acne treatment. If your acne is severe, persistent, or causing distress, the NHS recommends speaking to your GP, who may refer you to a dermatologist or prescribe stronger treatments.

 

How Does Eucerin Dermo Purifyer Compare to Other Oil Control Creams?

 

Feature Eucerin Dermo Purifyer Standard Oil-Free Moisturiser
Active sebum regulation Yes (L-Carnitine) No
Anti-inflammatory ingredient Yes (Licochalcone A) Rarely
Non-comedogenic Yes Not always
Dermatologically tested Yes Varies by brand

 

Is Eucerin Dermo Purifyer Suitable for Long-Term Use?

 

Yes, this cream is formulated for daily use and is suitable for ongoing application as part of a consistent skincare routine. Because it is free from fragrances and tested for sensitive skin, it is generally well-tolerated over extended periods. As with any topical product, if you notice persistent irritation or a worsening of your skin condition, stop use and consult a pharmacist or GP.

If you're managing acne alongside other skin concerns, our creams and ointments collection includes a range of dermatological products that may complement your routine.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Eucerin Dermo Purifyer Oil Control Adjunctive Soothing Cream 50ml specifications
Treatment category Acne-prone and oily skin care
Mechanism of action Sebum regulation (L-Carnitine); anti-inflammatory (Licochalcone A)
Effective for Reducing oiliness, soothing acne-irritated skin
Suitable for Oily, combination, acne-prone, and sensitive skin
Active ingredient Licochalcone A, L-Carnitine
Pack size 50ml
UK classification General Sale / Cosmetic skincare
Preparation Cream
Route of administration Topical (skin)

Specifications of Eucerin Dermo Purifyer Oil Control Adjunctive Soothing Cream 50ml

 

What Is Eucerin Dermo Purifyer and What Is It Used For?

 

Eucerin Dermo Purifyer Oil Control Adjunctive Soothing Cream is a topical skincare product designed for people with oily, acne-prone skin. It is used as an adjunctive treatment — meaning it supports and complements prescribed or recommended acne therapies rather than acting as a standalone acne cure. The cream helps to reduce excess sebum production, soothe skin redness and irritation, and restore a more balanced, comfortable skin texture.

Acne vulgaris is a chronic inflammatory skin condition affecting the pilosebaceous unit. The NHS notes that it is extremely common, particularly during adolescence, though it can persist into adulthood. Using a non-comedogenic, soothing moisturiser as part of a broader acne management plan can help maintain the skin barrier and reduce the dryness or irritation that often accompanies topical acne treatments.

 

What Do You Need to Know Before Using Eucerin Dermo Purifyer?

 

Before applying this cream, please read the following carefully:

Do not use this product if:

  • You are allergic to any of the ingredients, including Licochalcone A or L-Carnitine
  • You have open wounds, severely broken, or infected skin in the area of application
  • You have a known hypersensitivity to any component of the formulation

Warnings and precautions:

  • For external use only — avoid contact with eyes, mouth, and mucous membranes
  • If accidental eye contact occurs, rinse thoroughly with water
  • Discontinue use immediately if you develop a rash, increased redness, or signs of an allergic reaction
  • Keep out of reach of children
  • Not intended as a replacement for medical acne treatment — consult your GP if acne is severe or worsening

Known drug interactions:

  • No significant drug interactions have been identified for topical use of this product
  • If you are using prescription topical treatments (e.g. tretinoin, clindamycin), apply them separately and allow each product to absorb before applying the next
  • Consult your pharmacist if you are unsure about combining this cream with other topical medicines

 

How Should You Use Eucerin Dermo Purifyer Correctly?

 

Using this cream correctly will help you get the most benefit while minimising any risk of irritation. Follow these steps:

  1. Wash your hands thoroughly before application
  2. Cleanse your face with a gentle, soap-free cleanser suitable for acne-prone skin
  3. Pat your skin dry with a clean towel — do not rub
  4. Dispense a small, pea-sized amount of cream onto your fingertips
  5. Apply evenly across the face or affected areas, avoiding the eye contour and lips
  6. Allow the cream to absorb fully before applying any other products, including SPF or makeup
Indication Age Group Dose Frequency
Oily, acne-prone skin (adjunctive) Adults and adolescents (12+) Pea-sized amount Once or twice daily
Skin irritation from acne treatments Adults Thin layer to affected area Once daily (morning preferred)

If you are using this cream alongside other acne treatments from our skin care range, allow each product to absorb fully before layering the next.

 

What Are the Possible Side Effects of Eucerin Dermo Purifyer?

 

This cream is generally well-tolerated, particularly by those with sensitive skin. However, as with any topical product, some people may experience unwanted effects.

Common side effects:

  • Mild tingling or tightness immediately after application
  • Temporary redness at the site of application

Less common side effects:

  • Contact dermatitis (skin inflammation due to sensitivity to an ingredient)
  • Dryness or peeling, particularly if used alongside drying acne treatments
  • Itching or a burning sensation that persists beyond initial application

If you experience any signs of a serious allergic reaction — such as swelling of the face, difficulty breathing, or widespread hives — seek emergency medical attention immediately. The NHS advises that allergic skin reactions should always be assessed by a healthcare professional if they are severe or spreading.

 

How Should You Store Eucerin Dermo Purifyer Safely?

 

Correct storage helps maintain the product's integrity and safety. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Do not freeze
  • Keep the cap tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not transfer to another container

For more dermatological skincare products suited to sensitive or problem skin, browse our creams and ointments collection at Cured Pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Eucerin Dermo Purifyer Oil Control Cream online in the UK?

You can buy Eucerin Dermo Purifyer Oil Control Adjunctive Soothing Cream 50ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £9.38. It is available without a prescription and can be ordered conveniently from our skin care collection. No GP referral is needed for this over-the-counter product.

How does Eucerin Dermo Purifyer Oil Control Cream work in the skin?

The cream contains two key active ingredients: L-Carnitine, which regulates sebum production by the skin's oil glands, and Licochalcone A, a liquorice root extract with anti-inflammatory properties that calms redness and irritation. Together, they help reduce shine, soothe acne-irritated skin, and support the skin barrier without blocking pores. The non-comedogenic formula means it is specifically designed not to worsen breakouts.

How do I use Eucerin Dermo Purifyer Soothing Cream step by step?

Start by cleansing your face with a gentle, soap-free cleanser, then pat dry. Apply a small, pea-sized amount of the cream to your face or affected areas, avoiding the eye contour and lips. Allow it to absorb fully before applying any other skincare products, SPF, or makeup — once or twice daily is the recommended frequency.

What is the best time of day to apply Eucerin Dermo Purifyer?

The cream can be used both morning and evening, making it flexible for different routines. In the morning, applying it before SPF helps protect and balance the skin throughout the day. In the evening, it can be used after any prescribed acne treatments to soothe and restore the skin barrier overnight.

What are the side effects of Eucerin Dermo Purifyer Oil Control Cream?

Side effects are uncommon but may include mild tingling, temporary redness, or a slight tightness immediately after application. Less commonly, some people may experience contact dermatitis or itching if they are sensitive to a specific ingredient. If irritation persists or worsens, stop use and consult your pharmacist or GP.

Is Eucerin Dermo Purifyer suitable for sensitive skin?

Yes — the formula is dermatologically tested and specifically designed for oily, acne-prone, and sensitive skin types. It is fragrance-free and non-comedogenic, which means it is unlikely to cause irritation or block pores. However, if you have a known allergy to any of the listed ingredients, check the full ingredient list before use.

Who is eligible to use Eucerin Dermo Purifyer Oil Control Cream?

This cream is suitable for adults and adolescents aged 12 and over with oily or acne-prone skin. It is particularly beneficial for those already using topical acne treatments who need a gentle, non-irritating moisturiser to support their skin barrier. It is not recommended for use on broken, infected, or severely inflamed skin without medical advice.

Can I use Eucerin Dermo Purifyer with prescription acne treatments?

Yes, this cream is designed as an adjunctive product to complement acne treatments such as topical retinoids, antibiotics, or benzoyl peroxide. Apply your prescription treatment first, allow it to absorb, and then apply the soothing cream. Always check with your pharmacist or GP if you are unsure about combining products, as some active acne treatments can increase skin sensitivity.

How long does it take for Eucerin Dermo Purifyer to show results?

Many users notice a reduction in shine and improved skin comfort within the first few days of consistent use. More significant improvements in skin texture and reduced oiliness are typically observed after two to four weeks of daily application. Results will vary depending on skin type and whether the cream is used alongside other acne treatments.

How long can you use Eucerin Dermo Purifyer Oil Control Cream for?

The cream is formulated for long-term daily use as part of an ongoing skincare routine for oily or acne-prone skin. There is no defined maximum duration of use, provided the product is well-tolerated. If your skin condition changes significantly or you develop any adverse reactions, consult your pharmacist or GP for further guidance.

What happens if I accidentally apply too much Eucerin Dermo Purifyer?

Applying more than the recommended amount is unlikely to cause serious harm, but it may leave the skin feeling greasy or cause mild irritation. If excess product has been applied, gently blot the skin with a clean tissue. There is no need for medical attention unless you experience an unexpected allergic reaction.

Is Eucerin Dermo Purifyer an oily skin cream for acne that can replace my GP treatment?

No — this is an adjunctive soothing cream, not a standalone acne treatment. It is designed to support and complement medical acne therapies by soothing irritation and controlling oil, not to replace them. If your acne is moderate to severe, the NHS recommends consulting your GP for appropriate prescription treatment.

What are alternatives to Eucerin Dermo Purifyer Oil Control Cream?

Alternatives include other non-comedogenic moisturisers for acne-prone skin, such as La Roche-Posay Effaclar Mat or Cetaphil PRO Oil Control Moisturiser. You can also explore our creams and ointments collection for other dermatological skincare options. Speak to your pharmacist for personalised recommendations based on your skin type and current treatments.

Can I use Eucerin Dermo Purifyer during pregnancy?

There is no specific contraindication listed for use during pregnancy, but as with any skincare product, it is advisable to consult your GP or midwife before introducing new products during pregnancy or breastfeeding. This is particularly important if you are also using prescription acne treatments, some of which are contraindicated in pregnancy.

What are the latest findings on L-Carnitine and sebum control in acne-prone skin?

Research published in dermatological literature supports the role of L-Carnitine in reducing sebum excretion by interfering with the metabolic pathway of fatty acid synthesis in sebaceous glands. Licochalcone A has similarly been studied for its anti-inflammatory and antioxidant effects on acne-prone skin. These ingredients are well-established in adjunctive acne skincare and are supported by Eucerin's own clinical testing programme.

How Should You Use Eucerin Dermo Purifyer Oil Control Cream?

Using this cream correctly is straightforward, but a consistent technique will help you get the most from it. Always start with clean, dry skin — applying to unwashed skin can reduce absorption and effectiveness. Follow these steps each time you use the product:

What Is the Correct Dose of Eucerin Dermo Purifyer?

The amount you use matters. Too little may not provide adequate coverage; too much can leave the skin feeling greasy and may not improve results. A pea-sized amount is sufficient for the full face in most cases. The table below summarises recommended use by indication and age group.

When Is the Best Time to Use Eucerin Dermo Purifyer?

This cream can be used both morning and evening, depending on your routine and skin needs. In the morning, applying it after cleansing and before your SPF helps control oil production throughout the day and creates a smooth base for makeup. In the evening, it works well after any prescribed topical acne treatments, helping to soothe and restore the skin barrier while you sleep. If you find your skin becomes oily quickly during the day, a morning application is particularly beneficial.

How Long Can You Use Eucerin Dermo Purifyer For?

There is no defined maximum duration of use for this cream. It is formulated for ongoing daily use as part of a long-term skincare routine for oily or acne-prone skin. Many people use it continuously for months or years without issue, provided it remains well-tolerated. If your skin condition changes — for example, if acne worsens significantly or you develop new symptoms — stop use and speak to your pharmacist or GP. Regular review of your skincare routine is always a good idea, especially if you are also using prescription acne treatments.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Eucerin Dermo Purifyer?

Most people tolerate this cream well, and side effects are generally mild and temporary. Because the formula is dermatologically tested and fragrance-free, it is less likely to cause irritation than many other skincare products. That said, any topical product can occasionally cause a reaction, particularly in those with very sensitive skin.

  • Mild tingling or tightness immediately after application
  • Temporary redness at the site of application
  • A slight warming sensation on first use

What Are the Less Common Side Effects of Eucerin Dermo Purifyer?

Less frequently, some individuals may experience more noticeable skin reactions. These are not typical but are worth being aware of, particularly if you have a history of contact dermatitis or ingredient sensitivities.

  • Contact dermatitis — inflammation of the skin characterised by itching, redness, and possible blistering
  • Dryness or peeling, especially if used alongside drying acne treatments such as benzoyl peroxide
  • Persistent itching or a burning sensation that does not resolve after a few minutes
  • Localised swelling or hives at the application site

What Are the Serious Side Effects of Eucerin Dermo Purifyer?

Serious side effects are rare with topical skincare products, but they can occur in the event of a significant allergic reaction. If you experience any of the following, stop using the cream immediately and seek urgent medical attention:

  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Difficulty breathing or swallowing
  • Widespread hives or a rapidly spreading rash
  • Dizziness or feeling faint

These symptoms may indicate anaphylaxis, which is a medical emergency. Call 999 or go to your nearest A&E immediately if you suspect a severe allergic reaction.

What Should You Do If You Experience Side Effects of Eucerin Dermo Purifyer?

For mild side effects such as temporary redness or tingling, no specific action is usually needed — these often resolve within a few minutes of application. If irritation persists beyond 24 hours or worsens with continued use, stop applying the cream and consult your pharmacist. They can help you determine whether the reaction is related to this product or another element of your skincare routine. Do not attempt to self-treat a suspected allergic reaction with antihistamines alone if symptoms are severe.

Can Eucerin Dermo Purifyer Interact With Other Skincare Products or Medicines?

No significant drug interactions have been identified for this topical cream. However, using it alongside other active topical treatments — such as tretinoin, adapalene, or benzoyl peroxide — may increase the likelihood of skin dryness or irritation, as these treatments can already compromise the skin barrier. Always apply prescription treatments first, allow them to absorb, and then apply this soothing cream as a second step. If you are unsure about combining products, speak to your pharmacist before starting.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery