E45 Dermatological Cream

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E45 Dermatological Cream for Dry and Sensitive Skin

You can rely on this clinically proven moisturising cream to provide effective relief for dry, itchy and sensitive skin conditions. The gentle, fragrance-free formula has been specifically developed for people with eczema, dermatitis and other skin sensitivities that require daily care and protection.

This cream contains white soft paraffin and light liquid paraffin as active ingredients, which work together to restore your skin's natural moisture barrier. The formulation helps prevent water loss from your skin whilst providing long-lasting hydration that soothes irritation and reduces itching.

How This Moisturising Cream Works on Your Skin

The cream works by forming a protective layer on your skin's surface that locks in moisture and prevents further water loss. White soft paraffin acts as an occlusive agent, creating a barrier that helps your skin retain its natural moisture levels throughout the day.

Light liquid paraffin provides additional emollient properties that soften and smooth rough, dry patches of skin. Together, these ingredients help restore your skin's natural protective function whilst reducing inflammation and irritation associated with dry skin conditions.

Who Can Benefit from This Gentle Formula

This cream is suitable for you if you have dry, sensitive or eczema-prone skin that requires daily moisturising care. The gentle, hypoallergenic formula makes it appropriate for regular use on both your face and body, including delicate areas.

You may find this particularly helpful if you experience:

Dry, flaky or rough skin patches
Mild to moderate eczema or dermatitis
Skin irritation from environmental factors
Itching and discomfort from skin dryness

The cream is suitable for adults and children, making it an ideal choice for families managing various E45 dermatological cream needs. You can browse our complete range of skin care products for additional moisturising options.

Why This Preservative-Free Formula Matters

The preservative-free formulation reduces your risk of experiencing allergic reactions or skin sensitivities that can occur with products containing common preservatives like parabens or formaldehyde-releasing agents. This makes the cream particularly suitable if you have reactive or compromised skin.

Without preservatives, the cream maintains its gentle profile whilst still providing effective moisturising benefits. The simple ingredient list minimises potential irritants, allowing your skin to heal and recover from dryness without additional chemical stress.

Clinical Suitability and Storage Requirements

This cream has been dermatologically tested and is suitable for long-term daily use as part of your skincare routine. You can apply it as often as needed to maintain skin hydration and comfort, particularly after bathing or when your skin feels tight and dry.

Store the cream at room temperature below 25°C and keep the tube tightly closed when not in use. The cream should be used within the expiry date printed on the packaging and discarded if you notice any changes in colour, texture or smell.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

How to Apply E45 Dermatological Cream

Apply the cream to clean, dry skin as often as required throughout the day. Gently massage a thin layer into the affected areas until fully absorbed. You can use this cream on your face and body, avoiding the immediate eye area.

For best results, apply the cream after bathing or showering whilst your skin is still slightly damp. This helps to lock in moisture and maximise the hydrating benefits of the formulation.

When and How Often to Use

You can use this cream as frequently as needed to maintain skin comfort and hydration. Many people find applying it twice daily, morning and evening, provides optimal results for managing dry skin conditions.

During flare-ups of eczema or dermatitis, you may need to apply the cream more frequently. Listen to your skin's needs and adjust your application routine accordingly. The gentle formula allows for frequent use without causing irritation or clogging pores.

Possible Side Effects of E45 Dermatological Cream

Like all medicines, E45 Dermatological Cream can have side effects, although not everyone will experience them. Most people tolerate this cream well due to its gentle, preservative-free formulation, and you can find additional creams and ointments if you need alternative options.

The most commonly reported side effects are mild skin reactions that typically resolve quickly once you stop using the product. These reactions are usually related to individual sensitivities rather than the cream itself.

Known side effects may include:

Mild skin irritation or redness at application site
Temporary stinging or burning sensation
Increased skin sensitivity
Contact dermatitis in sensitive individuals
Allergic skin reactions
Localised swelling or inflammation
Skin rash or hives
Itching that worsens rather than improves

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.