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E45 Cream Pump Dispenser Dermatological for Dry and Condition Skin

E45 Cream Pump Dispenser Dermatological for Dry and Condition Skin

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  • ✔️ Soothes and moisturises dry, itchy, and flaking skin
  • ✔️ Clinically indicated for eczema, psoriasis, and ichthyosis
  • ✔️ Pump dispenser reduces contamination and aids one-handed use
  • ✔️ Contains hypoallergenic lanolin — suitable for sensitive skin
  • ✔️ Can double as a gentle soap substitute for daily cleansing

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Is E45 Cream for Dry Skin Right for You?

 

If you live with persistently dry, itchy, or flaking skin, you'll know how uncomfortable it can be — especially when it flares up in cold weather or after bathing. E45 cream for dry skin is one of the most widely used dermatological emollients in the UK, trusted by patients and clinicians alike for decades. Available here in a convenient pump dispenser format, it makes daily moisturising quicker and more hygienic than scooping from a tub. You can explore our full range of skin care products if you're looking for complementary options alongside your emollient routine.

The pump dispenser is particularly useful for people who apply emollient frequently throughout the day — it reduces the risk of contaminating the product and makes one-handed application much easier. Whether you're managing a long-term skin condition or simply dealing with seasonal dryness, this format offers real practical value.

 

How Does E45 Cream Work to Moisturise Skin?

 

E45 cream is an emollient, which means it works by softening and soothing the skin rather than treating an underlying cause. It contains three active ingredients that work together:

  • Light liquid paraffin (12.6%) — forms a thin film on the skin surface to reduce water loss through evaporation
  • White soft paraffin (14.5%) — occlusive agent that seals moisture into the outer layers of the skin
  • Anhydrous lanolin (hypoallergenic, 1%) — derived from wool fat, it helps the cream penetrate the skin and improves softness

Together, these ingredients restore the skin's natural barrier function. When the skin barrier is compromised — as it often is in eczema or psoriasis — moisture escapes more easily, leading to dryness, cracking, and irritation. Regular emollient use helps interrupt that cycle.

 

Who Should Use E45 Cream Pump Dispenser?

 

E45 cream is suitable for a wide range of people. It's used both as a standalone moisturiser and as part of a broader skin management plan recommended by a GP or dermatologist. It is appropriate for:

  • Adults and children with eczema or atopic dermatitis
  • People with psoriasis who need regular skin hydration
  • Individuals with ichthyosis or other chronic dry skin conditions
  • Anyone experiencing dry, flaking, or itchy skin due to environmental factors or frequent handwashing

It is not suitable for people with a known allergy to lanolin or any other ingredient in the formulation. If you're unsure whether this product is right for you, speak to your pharmacist before purchasing.

 

How Does E45 Cream Compare to Other Emollients?

 

Feature E45 Cream Pump Dispenser Diprobase Cream
Active ingredients Light liquid paraffin, white soft paraffin, lanolin Liquid paraffin, white soft paraffin
Contains lanolin Yes (hypoallergenic) No
Pump dispenser available Yes No (tube/tub only)
Suitable for eczema Yes Yes

 

Is E45 Cream Safe to Store and Use Long-Term?

 

E45 cream for dry skin is safe for long-term daily use when applied as directed. Store it below 25°C, away from direct sunlight and out of reach of children. The pump dispenser helps maintain product hygiene over time, as you're not introducing fingers into the container. If you're also managing a skin condition like eczema, you may find it helpful to browse our creams and ointments collection for additional treatment options recommended by your GP.

One important safety note: emollient products — including E45 cream — can soak into fabric and create a fire hazard. Keep clothing, bedding, and dressings away from open flames or other ignition sources when using any paraffin-based emollient. This is a known risk highlighted by the MHRA.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

E45 Cream Pump Dispenser Dermatological for Dry and Condition Skin specifications
Treatment category Emollient / Dermatological moisturiser
Mechanism of action Occlusive and humectant barrier formation to reduce transepidermal water loss
Effective for Dry skin, eczema, psoriasis, ichthyosis, dermatitis
Suitable for Adults, children, and babies (seek advice for under 12 months)
Active ingredients Light liquid paraffin 12.6%, White soft paraffin 14.5%, Anhydrous lanolin (hypoallergenic) 1%
Pack size 500g pump dispenser
UK classification General Sale List (GSL)
Drug class Emollient
Preparation Cream
Route of administration Topical (applied to skin)

Specifications of E45 Cream Pump Dispenser Dermatological for Dry and Condition Skin

 

What Is E45 Cream and What Is It Used For?

 

E45 cream is a dermatological emollient used to moisturise, soothe, and protect dry, itchy, and flaking skin. It is clinically indicated for a range of skin conditions including eczema, psoriasis, ichthyosis, and pruritus (itching) associated with dry skin. The NHS recommends emollients as a first-line treatment for conditions like eczema, and E45 cream is one of the most commonly used options in both primary care and self-care settings. The pump dispenser format makes it especially practical for people who need to apply emollient frequently throughout the day.

It works as both a leave-on moisturiser and a soap substitute when diluted with water, making it versatile for daily skin management. E45 cream for dry skin is available over the counter without a prescription.

 

What Do You Need to Know Before Using E45 Cream?

 

Before using E45 cream, read the following contraindications and warnings carefully:

  • Do not use if you are allergic to lanolin, light liquid paraffin, white soft paraffin, or any other ingredient in the formulation
  • Avoid contact with the eyes
  • Do not apply to broken, infected, or weeping skin without medical advice
  • Paraffin-based emollients pose a fire risk — keep away from open flames, cigarettes, and other ignition sources; this applies to clothing and bedding that may have absorbed the product
  • If your skin condition worsens or does not improve after two weeks of use, consult your GP
  • Seek medical advice before use if you are pregnant or breastfeeding, though topical emollients are generally considered low risk

Regarding drug interactions, no significant interactions with other medicines have been identified for topical emollients. However:

  • If you are using topical corticosteroids or other medicated creams, apply E45 cream at a different time to avoid diluting the active treatment
  • Allow at least 30 minutes between applying an emollient and a topical steroid

 

How Should You Use E45 Cream Pump Dispenser?

 

Using E45 cream correctly makes a real difference to how well it works. Follow these steps for best results:

  1. Wash and gently pat your skin dry before applying
  2. Press the pump dispenser to release a small amount of cream onto your fingertips or directly onto the skin
  3. Apply in smooth, downward strokes in the direction of hair growth — this reduces the risk of blocking hair follicles
  4. Massage gently until the cream is absorbed
  5. Reapply as often as needed throughout the day, particularly after washing hands or bathing
  6. As a soap substitute, mix a small amount with water and use to cleanse the skin, then rinse
Indication Age Group Dose Frequency
Dry skin / eczema Adults Apply liberally to affected area 2–3 times daily or as needed
Dry skin / eczema Children (1 year+) Apply liberally to affected area 2–3 times daily or as needed
Dry skin Babies (under 12 months) Small amount to affected area As directed by GP or pharmacist
Soap substitute All ages Small amount diluted with water At each wash

If you're also managing a skin condition in a young child, our baby and toddler collection includes additional products suitable for sensitive infant skin.

 

What Are the Possible Side Effects of E45 Cream?

 

E45 cream is generally very well tolerated. Side effects are uncommon, but it's worth knowing what to look out for.

Common side effects:

  • Mild stinging or burning sensation immediately after application, particularly on broken or very dry skin
  • Temporary greasiness or heaviness on the skin surface

Less common side effects:

  • Skin redness or irritation at the application site
  • Contact dermatitis — an allergic reaction that may cause a rash, itching, or swelling
  • Folliculitis (inflammation of hair follicles) if the cream is applied against the direction of hair growth

If you experience signs of a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — stop using the product immediately and seek urgent medical attention. Lanolin sensitivity, though rare, is the most likely cause of an allergic response to this product.

 

How Should You Store E45 Cream?

 

Correct storage keeps the product effective and safe throughout its shelf life. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the pump cap closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not store near open flames or ignition sources — paraffin-based products are flammable when absorbed into fabric

For a broader selection of dermatological and skin health products, you can also browse our skin care collection at Cured Pharmacy.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy E45 cream pump dispenser online in the UK?

You can buy the E45 cream pump dispenser directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter emollient. Simply add it to your basket and choose your preferred delivery option at checkout.

How does E45 cream work on dry skin?

E45 cream works by forming a protective occlusive barrier on the skin surface that reduces transepidermal water loss — essentially locking moisture in. Its combination of light liquid paraffin, white soft paraffin, and hypoallergenic lanolin softens and soothes the outer layers of the skin. Regular use helps restore the skin's natural barrier function, which is often compromised in conditions like eczema.

How do I use the E45 cream pump dispenser step by step?

Press the pump to dispense a small amount of cream onto your fingertips or directly onto the affected area. Apply in smooth, downward strokes following the direction of hair growth, then gently massage until absorbed. Repeat as often as needed throughout the day, particularly after washing or bathing.

How often should I apply E45 cream for eczema?

For eczema, the NHS recommends applying emollients frequently — at least two to three times daily, and more often during flare-ups. Consistency is key; applying E45 cream even when your skin feels relatively comfortable helps maintain the skin barrier and reduce the frequency of flares. Your GP or dermatologist may advise a specific routine tailored to your condition.

What are the side effects of E45 cream?

Side effects are uncommon but can include mild stinging, temporary skin redness, or irritation at the application site. In rare cases, people with a lanolin sensitivity may develop contact dermatitis — a localised allergic rash. If you notice swelling, widespread redness, or difficulty breathing, stop use immediately and seek medical attention.

Is E45 cream suitable for babies and young children?

Yes, E45 cream is suitable for use in children and babies, though you should seek advice from a GP or pharmacist before applying any emollient to a baby under 12 months. Our baby and toddler collection also includes other products designed for sensitive infant skin. Always patch-test a small area first when using any new product on a child.

Can I use E45 cream during pregnancy?

E45 cream is generally considered safe to use during pregnancy as a topical emollient, since its active ingredients are not significantly absorbed into the bloodstream. That said, you should always speak to your midwife or GP before starting any new skincare product during pregnancy. They can confirm it is appropriate for your individual circumstances.

Can E45 cream be used as a soap substitute?

Yes — E45 cream can be used as a soap substitute by mixing a small amount with water and using it to cleanse the skin before rinsing off. This is particularly useful for people with eczema or sensitive skin, as conventional soaps and shower gels can strip the skin's natural oils and worsen dryness. The NHS recommends soap substitutes as part of an emollient-based skincare routine for eczema.

What is the best time to apply E45 cream?

The most effective times to apply E45 cream are immediately after bathing or washing, when the skin is still slightly damp — this helps seal in moisture. Applying before bed is also beneficial, as the skin has time to absorb the emollient overnight without being washed off. For very dry or eczema-prone skin, midday application is also recommended.

What are the alternatives to E45 cream for dry skin?

Common alternatives include Diprobase cream, Cetraben, Doublebase gel, Aveeno, and Zerobase — all of which are emollients available over the counter. The right choice depends on your skin type, the severity of your condition, and whether you have any ingredient sensitivities. You can browse our full range of creams and ointments to compare options.

Is E45 cream safe to use on the face?

E45 cream can be applied to the face for dry skin conditions, but avoid contact with the eyes and mucous membranes. Some people find paraffin-based creams feel heavy on facial skin, particularly if they have oily or acne-prone areas. If you're unsure, ask your pharmacist or GP whether E45 cream is the most suitable option for facial use in your case.

How long can I use E45 cream for?

E45 cream is safe for long-term, continuous use as a daily emollient — there is no maximum duration of use for most people. Many individuals with chronic conditions like eczema or psoriasis use emollients indefinitely as part of their ongoing skin management. If your skin condition changes significantly or does not respond to treatment, consult your GP for a review.

Does E45 cream contain steroids?

No — E45 cream does not contain any corticosteroids. It is a plain emollient containing light liquid paraffin, white soft paraffin, and hypoallergenic lanolin. If your GP has prescribed a topical steroid alongside an emollient, these should be applied separately, with at least 30 minutes between applications.

Is there a fire risk with E45 cream?

Yes — as with all paraffin-based emollients, E45 cream poses a fire hazard when it soaks into fabric such as clothing, bedding, or dressings. The MHRA has issued guidance advising patients to keep away from open flames, cigarettes, and other ignition sources when using paraffin-based products. Washing fabric regularly reduces the build-up of residue, but the risk is not entirely eliminated by washing alone.

What does the latest research say about emollients like E45 cream?

Current clinical evidence supports the regular use of emollients as a cornerstone of dry skin and eczema management, with guidelines from NICE and the NHS recommending them as first-line treatment. Research continues to explore whether early emollient use in infants can reduce the risk of developing eczema, though findings to date have been mixed. E45 cream for dry skin remains a well-established, evidence-based option within dermatological practice.

How Should You Use E45 Cream Pump Dispenser?

Using E45 cream correctly helps you get the most from each application and reduces the risk of side effects such as folliculitis. Always apply to clean skin, and follow the steps below for best results.

What Is the Correct Dose of E45 Cream?

There is no fixed maximum dose for E45 cream — it should be applied liberally and as often as needed to keep the skin moisturised. The table below provides general guidance based on indication and age group.

When Is the Best Time to Use E45 Cream?

The most effective time to apply E45 cream is immediately after bathing or washing, while the skin is still slightly damp — this helps trap moisture in the outer skin layers. Applying before bed is also particularly beneficial, as the emollient has time to work overnight without being disturbed by washing or activity. For people with eczema or very dry skin, a midday application is also recommended to maintain hydration throughout the day.

How Long Can You Use E45 Cream For?

E45 cream is safe for long-term, continuous daily use. There is no recommended maximum duration — many people with chronic dry skin conditions such as eczema or psoriasis use emollients indefinitely as part of their ongoing skin management routine. If your skin condition does not improve after two weeks of regular use, or if it worsens at any point, consult your GP or pharmacist for further assessment. They may recommend a different emollient or an additional treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of E45 Cream?

E45 cream is well tolerated by most people, and serious side effects are uncommon. That said, some individuals — particularly those with very sensitive or broken skin — may notice mild reactions when they first start using it.

  • Mild stinging or burning sensation immediately after application
  • Temporary greasiness or heaviness on the skin surface
  • Slight skin redness at the application site

What Are the Less Common Side Effects of E45 Cream?

Less frequently, some people experience reactions that may require them to stop using the product or seek advice from a pharmacist. These are more likely in individuals with a known sensitivity to one of the ingredients.

  • Contact dermatitis — a localised allergic rash causing itching, redness, or blistering
  • Folliculitis — inflammation of hair follicles, often caused by applying cream against the direction of hair growth
  • Increased skin sensitivity in areas where the cream is applied frequently

What Are the Serious Side Effects of E45 Cream?

Serious side effects are rare but require immediate medical attention if they occur. Lanolin — one of the active ingredients — is the most likely cause of an allergic reaction in susceptible individuals, though the formulation uses a hypoallergenic grade. Signs of a serious allergic reaction (anaphylaxis) include swelling of the face, lips, tongue, or throat, difficulty breathing, a widespread skin rash, or dizziness. If you experience any of these symptoms, stop using E45 cream immediately and call 999 or go to your nearest A&E department.

What Should You Do If You Experience Side Effects?

For mild side effects such as stinging or temporary redness, you may simply need to reduce the frequency of application or try applying to a smaller area first. If you develop a rash or signs of contact dermatitis, stop using the product and speak to your pharmacist or GP — they can help identify whether the reaction is related to E45 cream or another product you're using. Do not ignore a worsening skin reaction, as untreated contact dermatitis can spread.

Can E45 Cream Interact With Other Medicines?

No significant drug interactions have been identified for E45 cream when used topically. However, if you are using a topical corticosteroid or other medicated cream alongside E45, you should apply them at separate times — ideally with at least 30 minutes between applications — to avoid diluting the active treatment. Always inform your GP or pharmacist about all products you are applying to your skin, including over-the-counter emollients.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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