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Dermacool Menthol Cream 500g Pump

Dermacool Menthol Cream 500g Pump

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  • ✔️ Soothes itching from eczema, dermatitis, and dry skin
  • ✔️ Cooling menthol targets itch receptors for fast relief
  • ✔️ Steroid-free formula suitable for regular daily use
  • ✔️ 500g pump dispenser for hygienic, easy application
  • ✔️ Suitable for adults and children aged 2 years and over

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Is Menthol Cream for Itchy Skin Right for You?

 

If you've ever dealt with persistent itching — whether from eczema, dry skin, or an irritating rash — you'll know how exhausting it can be. Scratching brings only momentary relief, and often makes things worse. That's where menthol cream for itchy skin comes in. Dermacool Menthol Cream 500g Pump contains 0.5% menthol in an aqueous cream base, offering a cooling, soothing sensation that helps interrupt the itch-scratch cycle. It's a well-established, clinically recognised option for managing pruritus (the medical term for itching) associated with a range of skin conditions. You can explore the full range of topical options in our creams and ointments collection.

Dermacool is widely used across the UK, including in NHS settings, and is available over the counter without a prescription. The 500g pump format is particularly practical — it makes dispensing hygienic and straightforward, especially if you're applying it regularly throughout the day.

 

How Does Dermacool Menthol Cream Work on the Skin?

 

Menthol works by activating specific cold-sensitive receptors in the skin known as TRPM8 receptors. When these receptors are stimulated, they send a cooling signal to the brain that effectively competes with — and temporarily overrides — the itch sensation. It's a well-understood mechanism, and it's why menthol has been used in topical preparations for decades.

  • Menthol binds to TRPM8 cold receptors in the skin's nerve endings
  • A cooling signal is transmitted to the central nervous system
  • This signal competes with the itch impulse, reducing the perceived urge to scratch
  • The aqueous cream base also provides light moisturisation, helping to support the skin barrier

Importantly, Dermacool does not contain steroids or antihistamines. It works purely through this counter-stimulation mechanism, making it suitable for people who want a non-medicated approach to itch relief.

 

Who Should Use Dermacool Menthol Cream?

 

Dermacool Menthol Cream is suitable for a broad range of people experiencing itching from various causes. It's particularly useful for those managing chronic skin conditions where itch is a daily challenge. That said, it's not a treatment for the underlying condition — it manages the symptom of itch rather than addressing the root cause.

  • Adults and children aged 2 years and over with itchy skin
  • People with eczema or atopic dermatitis experiencing itch flares
  • Those with dry, irritated, or sensitive skin
  • Individuals seeking a steroid-free option for itch relief

If your itching is severe, widespread, or accompanied by other symptoms such as swelling or difficulty breathing, seek medical advice promptly rather than self-treating.

 

How Does Dermacool Compare to Other Antipruritic Creams?

 

Feature Dermacool Menthol Cream 0.5% Hydrocortisone 1% Cream
Active ingredient Menthol 0.5% Hydrocortisone 1%
Mechanism Counter-stimulation via TRPM8 receptors Anti-inflammatory (corticosteroid)
Steroid-free Yes No
Suitable for long-term use Generally yes, with pharmacist guidance Limited — max 7 days on face

 

Is Dermacool Menthol Cream Suitable for Sensitive Skin?

 

Dermacool Menthol Cream is formulated in an aqueous cream base, which is generally well tolerated by most skin types, including sensitive skin. However, aqueous cream used as a leave-on emollient has been associated with skin irritation in some individuals — particularly those with eczema — so it's worth monitoring your skin's response when you first start using it. If you notice increased redness or stinging, discontinue use and speak to your pharmacist.

For those managing broader skin health concerns, our skin care collection includes a range of complementary products. Store Dermacool below 25°C, away from direct sunlight, and keep the pump out of reach of children. This menthol cream for itchy skin should not be applied to broken skin, near the eyes, or on mucous membranes.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Dermacool Menthol Cream 500g Pump specifications
Treatment category Antipruritic / Emollient
Mechanism of action TRPM8 cold receptor activation (counter-stimulation)
Effective for Itching associated with eczema, dermatitis, dry skin
Suitable for Adults and children aged 2 years and over
Active ingredient Menthol 0.5% w/w
Pack size 500g pump
UK classification General Sale List (GSL)
Drug class Antipruritic
Preparation Cream (aqueous base)
Route of administration Topical (cutaneous)

Specifications of Dermacool Menthol Cream 500g Pump

 

What Is Dermacool Menthol Cream and What Is It Used For?

 

Dermacool Menthol Cream 500g Pump is a topical antipruritic preparation containing 0.5% menthol in an aqueous cream base. It is used to relieve itching (pruritus) associated with a variety of skin conditions, including eczema, contact dermatitis, dry skin, and insect bites. The cooling effect of menthol provides symptomatic relief by temporarily reducing the sensation of itch at the skin surface. It does not treat the underlying cause of the skin condition.

 

What Do You Need to Know Before Using Dermacool Menthol Cream?

 

Before applying Dermacool, read the following carefully. Do not use this product if any of the contraindications below apply to you.

Do not use Dermacool if you:

  • Are allergic to menthol or any other ingredient in the formulation
  • Have broken, infected, or weeping skin at the application site
  • Are applying to the eye area or mucous membranes
  • Are using it on a child under 2 years without medical advice

Warnings and precautions:

  • Aqueous cream used as a leave-on preparation may cause skin irritation in some people with eczema — monitor your skin's response
  • Avoid contact with eyes; if accidental contact occurs, rinse thoroughly with water
  • Do not apply near an open flame — menthol-containing preparations are flammable
  • If your skin condition worsens or does not improve within 7 days, consult your GP or pharmacist
  • Tell your pharmacist if you are pregnant or breastfeeding before use

Drug interactions:

  • No clinically significant drug interactions are currently known for topical menthol at this concentration
  • If you are using other topical preparations on the same area, speak to your pharmacist to avoid potential interactions

 

How Should You Use Dermacool Menthol Cream?

 

Always use Dermacool exactly as directed on the label or as advised by your pharmacist. The pump dispenser makes it easy to apply a consistent amount without contaminating the product.

  1. Wash and dry your hands before applying the cream
  2. Press the pump to dispense a small amount of cream onto your fingertips
  3. Apply a thin, even layer to the affected area of skin
  4. Gently smooth in — do not rub vigorously
  5. Wash your hands after application unless the hands are the area being treated
  6. Repeat up to three to four times daily, or as directed by your pharmacist
Indication Age Group Dose Frequency
Itching (eczema, dry skin) Adults Thin layer to affected area Up to 3–4 times daily
Itching (eczema, dry skin) Children 2–12 years Thin layer to affected area Up to 3 times daily
Itching (eczema, dry skin) Under 2 years Only on medical advice As directed by GP

If you are managing eczema alongside other conditions, you may also find our pain relief collection useful for associated discomfort.

 

What Are the Possible Side Effects of Dermacool Menthol Cream?

 

Like all medicines, Dermacool Menthol Cream can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the area of application.

Common side effects:

  • Mild cooling or tingling sensation at the application site (this is expected and part of the mechanism)
  • Temporary skin redness
  • Mild stinging, particularly on sensitive or inflamed skin

Less common side effects:

  • Contact dermatitis (allergic skin reaction) — characterised by increased redness, itching, or blistering
  • Skin dryness or irritation with prolonged use of aqueous cream base

Stop using the cream and seek medical advice if you develop signs of a severe allergic reaction, including significant swelling, difficulty breathing, or widespread rash.

 

How Should You Store Dermacool Menthol Cream?

 

Correct storage helps maintain the product's quality and safety throughout its shelf life.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and sources of heat
  • Keep the pump cap closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

For further guidance on managing skin conditions, the NHS provides detailed information on eczema and related conditions. You can also browse our allergy and hay fever collection if itching is linked to an allergic response.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Dermacool Menthol Cream 500g online in the UK?

You can order Dermacool Menthol Cream 500g Pump directly from Cured Pharmacy, a GPhC-registered online pharmacy. It is available without a prescription as a General Sale List (GSL) medicine. Simply add it to your basket and choose your preferred delivery option at checkout.

How does Dermacool Menthol Cream work on itchy skin?

Menthol activates TRPM8 cold-sensitive receptors in the skin, generating a cooling signal that competes with and temporarily overrides the itch impulse sent to the brain. This counter-stimulation mechanism is well established in dermatology and provides fast-acting localised relief. It does not contain steroids or antihistamines, so it works purely through this sensory pathway.

How do I apply Dermacool Menthol Cream step by step?

Wash and dry your hands, then press the pump to dispense a small amount of cream onto your fingertips. Apply a thin, even layer to the affected area and smooth it in gently — avoid rubbing vigorously. Wash your hands afterwards unless the hands themselves are being treated, and repeat up to three to four times daily.

What is the correct dose of Dermacool Menthol Cream for adults?

Adults should apply a thin layer of Dermacool Menthol Cream to the affected area up to three to four times daily. There is no fixed quantity per application — use enough to cover the area with a light film. Always follow the directions on the label or as advised by your pharmacist.

When is the best time to use Dermacool Menthol Cream?

You can apply Dermacool whenever itching is troublesome — there is no single "best" time, as it works on demand. Many people find it particularly helpful at night when itch tends to worsen, or after bathing when the skin is clean and slightly warm. Applying it consistently throughout the day helps maintain relief.

Can Dermacool Menthol Cream be used on children?

Dermacool Menthol Cream is generally suitable for children aged 2 years and over, applied up to three times daily. For children under 2 years, always consult a GP or pharmacist before use, as menthol preparations are not routinely recommended for very young children. If you are managing a child's skin condition, our baby and toddler collection may also be helpful.

Is Dermacool Menthol Cream suitable for eczema?

Yes, Dermacool is commonly used to relieve the itch associated with eczema and atopic dermatitis. It does not treat the underlying inflammation but helps manage the itch-scratch cycle, which can prevent further skin damage. For a broader approach to eczema management, speak to your GP or pharmacist about a full emollient and treatment plan.

What are the side effects of Dermacool Menthol Cream?

Side effects are uncommon but may include mild tingling, temporary redness, or a slight stinging sensation at the application site — these are generally expected and short-lived. Less commonly, some people may experience contact dermatitis, particularly if they are sensitive to menthol or other ingredients in the aqueous cream base. If you notice worsening redness, blistering, or swelling, stop use and seek pharmacist or GP advice.

Who is eligible to use Dermacool Menthol Cream?

Dermacool Menthol Cream is suitable for most adults and children aged 2 years and over who experience itching from conditions such as eczema, dry skin, or contact dermatitis. It is not suitable for use on broken, infected, or weeping skin, or near the eyes. People who are pregnant or breastfeeding should seek pharmacist advice before use.

What happens if I accidentally apply too much Dermacool Menthol Cream?

Applying more than the recommended amount is unlikely to cause serious harm, but it may intensify the cooling sensation and potentially cause skin irritation. If you accidentally apply a large amount, wipe off the excess with a clean cloth and rinse the area with water if needed. If you are concerned, contact your pharmacist for advice.

How long can you use Dermacool Menthol Cream for?

Dermacool can be used for as long as symptoms persist, but if your itching has not improved after 7 days of regular use, you should consult your GP or pharmacist to rule out an underlying cause. Long-term use of aqueous cream as a leave-on emollient has been associated with skin irritation in some individuals, so it is worth reviewing your skin's response periodically. Your pharmacist can advise on whether a different emollient base might be more suitable for extended use.

What are the alternatives to Dermacool Menthol Cream?

Alternatives for itch relief include hydrocortisone 1% cream (for inflammatory itch), calamine lotion (for mild itch and insect bites), and other menthol-containing preparations at different concentrations. The right choice depends on the cause of your itching — a pharmacist can help you select the most appropriate option. You can also browse our skin care collection for a wider range of topical products.

Can I use Dermacool Menthol Cream on my face?

Dermacool can be applied to facial skin, but you must avoid the eye area and mucous membranes entirely. The cooling sensation of menthol can be particularly intense on facial skin, so apply sparingly and monitor for any irritation. If you experience stinging around the eyes or nose, rinse with water immediately and discontinue use on the face.

Does Dermacool Menthol Cream interact with other medicines?

No clinically significant drug interactions are currently known for topical menthol 0.5% at this concentration. However, if you are using other topical preparations on the same area of skin — such as steroid creams or antibiotic ointments — speak to your pharmacist before combining them. Applying multiple topical products to the same area simultaneously may affect absorption or cause irritation.

What are the latest findings on menthol cream for itchy skin?

Research continues to support the use of topical menthol as an effective antipruritic agent, with studies confirming its action via TRPM8 cold receptor activation as a well-understood mechanism for itch relief. Clinical guidance from the NHS and dermatology bodies recognises menthol-containing preparations as a useful option within broader itch management strategies. Always check with your pharmacist or GP for the most up-to-date guidance relevant to your specific condition.

How Should You Use Dermacool Menthol Cream?

Dermacool Menthol Cream is for external use only. Always read the label before use and follow the instructions carefully. The 500g pump dispenser makes application straightforward and hygienic — press the pump once to release a small amount of cream, which is usually sufficient for a localised area.

Avoid applying the cream to broken, infected, or weeping skin. Do not apply near the eyes, mouth, or other mucous membranes. If accidental contact with the eyes occurs, rinse immediately with plenty of clean water.

What Is the Correct Dose of Dermacool Menthol Cream?

The dose varies slightly depending on age and the severity of itching. Always use the smallest amount that provides adequate relief. Do not apply more frequently than directed, as this will not improve results and may increase the risk of skin irritation.

When Is the Best Time to Use Dermacool Menthol Cream?

There is no single fixed time to apply Dermacool — it works on demand, so you can use it whenever itching becomes troublesome. Many people find it particularly helpful after bathing, when the skin is clean and slightly warm, as this can help the cream absorb more effectively. Applying it before bed is also a common approach, since itch often intensifies at night and can disrupt sleep.

If you are using other topical treatments such as emollients or steroid creams, leave at least 30 minutes between applications to allow each product to absorb properly and avoid diluting their effect.

How Long Can You Use Dermacool Menthol Cream For?

Dermacool can be used for as long as symptoms persist. However, if your itching has not improved after 7 days of consistent use, you should consult your GP or pharmacist to investigate the underlying cause. Prolonged use of aqueous cream as a leave-on preparation has been associated with skin irritation in some individuals, particularly those with eczema, so it is worth reviewing your skin's response regularly.

If you are managing a long-term skin condition, your pharmacist or GP may recommend incorporating Dermacool into a broader skin care routine alongside other emollients or prescribed treatments.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Dermacool Menthol Cream?

Most people tolerate Dermacool Menthol Cream well, and side effects are generally mild and short-lived. The cooling or tingling sensation you feel after application is an expected part of how the cream works — it is not a side effect in the traditional sense, but rather the mechanism of action. That said, some people do experience localised reactions, particularly when first using the product.

  • Mild tingling or cooling sensation at the application site
  • Temporary skin redness
  • Slight stinging, especially on inflamed or sensitive skin

What Are the Less Common Side Effects of Dermacool Menthol Cream?

Less commonly, some individuals may experience a more pronounced reaction to either the menthol or the aqueous cream base. Aqueous cream used as a leave-on emollient has been associated with skin barrier disruption in some people with eczema, which can paradoxically worsen dryness or irritation over time. If you notice any of the following, stop using the cream and speak to your pharmacist.

  • Increased skin dryness or flaking with prolonged use
  • Persistent redness or warmth at the application site
  • Mild contact dermatitis — itching, redness, or small blisters
  • Skin sensitivity that worsens rather than improves

What Are the Serious Side Effects of Dermacool Menthol Cream?

Serious side effects are rare with topical menthol at 0.5% concentration. However, a small number of people may develop a hypersensitivity or allergic reaction to menthol or another ingredient in the formulation. Signs of a serious allergic reaction (anaphylaxis) include widespread rash, significant swelling of the face or throat, difficulty breathing, or dizziness. This requires immediate medical attention — call 999 or go to your nearest A&E department.

Do not apply Dermacool to large areas of broken or damaged skin, as increased absorption through compromised skin could theoretically heighten the risk of systemic effects, though this is not well documented at this concentration.

What Should You Do If You Experience Side Effects?

If you experience mild irritation, reduce the frequency of application and monitor your skin's response. For moderate reactions such as persistent redness or contact dermatitis, stop using the cream and consult your pharmacist, who can advise on alternative products. For any signs of a serious allergic reaction, seek emergency medical help immediately.

You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Reporting side effects helps improve the safety information available for all medicines.

Can Dermacool Menthol Cream Interact With Other Medicines?

No clinically significant interactions are currently known for topical menthol 0.5% when used as directed. If you are applying other topical preparations — such as corticosteroid creams, antibiotic ointments, or other emollients — to the same area of skin, allow at least 30 minutes between applications. Combining multiple topical products simultaneously may affect absorption or cause localised irritation. Always inform your pharmacist of all medicines you are currently using, including topical treatments.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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