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Dermacool 5% Menthol In Aqueous Cream – 100g

Dermacool 5% Menthol In Aqueous Cream – 100g

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  • ✔️ Relieves itching from eczema, dermatitis, and psoriasis fast
  • ✔️ 5% menthol concentration delivers strong, cooling antipruritic relief
  • ✔️ Non-steroidal formula safe for frequent daily application
  • ✔️ Aqueous cream base moisturises and helps restore the skin barrier
  • ✔️ Suitable for adults and children over two years of age

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Is Dermacool the Right Menthol Cream for Itching?

 

If you've ever dealt with the relentless urge to scratch that comes with eczema or dermatitis, you'll know how exhausting it can be. Dermacool 5% Menthol In Aqueous Cream is a topical preparation designed to bring fast, soothing relief to itchy, irritated skin. It contains 5% menthol — one of the higher over-the-counter concentrations available — dispersed in a simple aqueous cream base that also helps to hydrate dry skin. You can find it alongside other creams and ointments at Cured Pharmacy, making it easy to order from the comfort of home.

Itching — or pruritus — is one of the most common and distressing symptoms associated with inflammatory skin conditions. According to the NHS, eczema affects around 1 in 5 children and 1 in 10 adults in the UK, and persistent itching is often the symptom that most affects quality of life. Menthol cream for itching has been used in dermatology for decades precisely because it offers a non-steroidal, non-sedating way to interrupt the itch-scratch cycle.

 

How Does Dermacool 5% Menthol Cream Work on Itchy Skin?

 

The mechanism behind menthol's itch-relieving effect is well understood. Rather than simply masking discomfort, menthol acts on specific nerve receptors in the skin to produce a genuine physiological response. Here's how it works:

  • Menthol binds to TRPM8 receptors — cold-sensitive ion channels found in sensory nerve fibres in the skin.
  • Activating these receptors triggers a cooling sensation, which competes with and temporarily overrides the itch signal travelling to the brain.
  • This is sometimes called counter-stimulation or the "gate control" effect — essentially, one sensation drowns out another.
  • The aqueous cream base simultaneously forms a light occlusive layer on the skin surface, reducing transepidermal water loss and helping to restore the skin barrier.

The result is a dual action: cooling relief from the itch itself, plus gentle moisturisation to address the dryness that so often accompanies conditions like eczema and psoriasis.

 

Who Should Consider Using Dermacool 5% Menthol Cream?

 

Dermacool 5% is suitable for adults and children over 2 years of age who experience itching associated with a range of skin conditions. It's particularly useful when you want to avoid topical steroids or antihistamines, or when you need something you can apply frequently throughout the day. It's worth browsing the wider skin care range if you're managing multiple skin concerns alongside itching.

  • Adults and older children with eczema or atopic dermatitis
  • People with psoriasis experiencing localised itch
  • Those with insect bite reactions or mild urticaria
  • Individuals seeking a non-steroidal, non-sedating antipruritic option

 

How Does Dermacool 5% Compare to Lower-Strength Menthol Creams?

 

Feature Dermacool 5% Menthol Cream Dermacool 1% Menthol Cream
Menthol concentration 5% 1%
Cooling intensity Stronger cooling effect Milder, gentler sensation
Suitable for sensitive skin Use with caution Generally better tolerated
Typical use case Moderate to severe itch Mild itch, children, sensitive areas

 

Is Dermacool 5% Menthol Cream Safe to Store and Use Long-Term?

 

Dermacool 5% Menthol In Aqueous Cream should be stored below 25°C, away from direct sunlight and out of reach of children. Once opened, use within the period indicated on the packaging. Do not use the cream on broken, infected, or weeping skin, and always avoid contact with the eyes and mucous membranes. If you are pregnant, breastfeeding, or using other topical medicines on the same area of skin, speak to your pharmacist before starting use.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Dermacool 5% Menthol In Aqueous Cream – 100g specifications
Treatment category Antipruritic / Emollient
Mechanism of action TRPM8 receptor agonist — produces cooling sensation to relieve itch
Effective for Itching associated with eczema, dermatitis, psoriasis, insect bites
Suitable for Adults and children over 2 years
Active ingredient Menthol 5% w/w
Pack size 100g
Strength 5%
UK classification General Sale List (GSL)
Drug class Topical antipruritic
Preparation Cream
Route of administration Topical (cutaneous)

Specifications of Dermacool 5% Menthol In Aqueous Cream – 100g

 

What Is Dermacool 5% Menthol In Aqueous Cream and What Is It Used For?

 

Dermacool 5% Menthol In Aqueous Cream is an over-the-counter topical preparation containing 5% menthol in an aqueous (water-based) cream base. It is used to relieve the itching — known medically as pruritus — associated with a range of skin conditions. These include eczema, atopic dermatitis, contact dermatitis, psoriasis, and reactions to insect bites. The NHS describes eczema as a condition that causes the skin to become itchy, dry, cracked, and sore, and managing that itch is central to day-to-day comfort for many people living with the condition.

Dermacool works by producing a cooling sensation on the skin surface, which temporarily interrupts the itch signal. It does not treat the underlying cause of the skin condition, but it can provide meaningful symptomatic relief, particularly when used as part of a broader skin care routine that includes regular emollient use.

 

What Do You Need to Know Before Using Dermacool 5% Menthol Cream?

 

Before applying Dermacool, read the following carefully. This cream is for external use only. Do not use it if any of the following apply to you:

  • You are allergic to menthol, aqueous cream, or any other ingredient in the formulation
  • The skin in the affected area is broken, infected, weeping, or severely inflamed
  • You need to apply it near the eyes, mouth, or other mucous membranes
  • You are applying it to a child under 2 years of age without medical advice

There are also some important warnings to be aware of:

  • Aqueous cream used as a leave-on emollient has been associated with skin reactions in some people with eczema — if irritation worsens, stop use and consult a pharmacist
  • Do not use near naked flames or heat sources — emollient-based products can be flammable when they soak into fabric
  • If you are pregnant or breastfeeding, speak to your pharmacist or GP before use
  • Keep out of reach of children

No significant drug interactions are currently known for topically applied menthol at this concentration. However, avoid applying Dermacool at the same time as other topical medicines to the same area of skin without pharmacist guidance.

 

How Should You Apply Dermacool 5% Menthol Cream Correctly?

 

Using Dermacool correctly will help you get the most from it while minimising the risk of irritation. Follow these steps each time you apply it:

  1. Wash and gently pat dry the affected area of skin before applying.
  2. Take a small amount of cream on clean fingertips.
  3. Apply a thin, even layer to the itchy area.
  4. Smooth gently in the direction of hair growth — do not rub vigorously.
  5. Allow the cream to absorb before covering with clothing or dressings.
  6. Wash your hands thoroughly after application, unless your hands are the area being treated.
Indication Age Group Dose Frequency
Itching from eczema or dermatitis Adults Thin layer to affected area As needed, up to several times daily
Itching from eczema or dermatitis Children over 2 years Thin layer to affected area As needed — seek pharmacist advice
Insect bite or mild urticaria Adults Thin layer to affected area As needed

If you are also using other skin care products or topical steroids, apply Dermacool at a different time of day to avoid diluting the effect of either product.

 

What Are the Possible Side Effects of Dermacool 5% Menthol Cream?

 

Side effects with Dermacool are uncommon, but as with any topical product, some people may experience a reaction. The NHS advises that if a skin product causes increased redness, stinging, or swelling, you should stop using it and seek advice from a pharmacist or GP.

Common side effects:

  • Mild tingling or cooling sensation at the application site (this is expected and usually well tolerated)
  • Temporary redness of the skin

Less common side effects:

  • Skin irritation or a burning sensation, particularly on sensitive or broken skin
  • Contact dermatitis — an allergic reaction to one of the ingredients
  • Worsening of eczema symptoms in some individuals sensitive to aqueous cream base

If you experience any severe reaction, including significant swelling, blistering, or difficulty breathing, seek urgent medical attention.

 

How Should You Store Dermacool 5% Menthol Cream Safely?

 

Correct storage helps maintain the quality and safety of the product. You can also explore our range of creams and ointments for complementary skin care options.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze
  • Keep the lid tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the packaging
  • Do not store near naked flames — emollient-containing products can be a fire hazard when absorbed into fabric

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Dermacool 5% Menthol In Aqueous Cream online in the UK?

You can buy Dermacool 5% Menthol In Aqueous Cream 100g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as a General Sale List medicine. Simply add it to your basket and it will be dispatched to your door.

How does Dermacool 5% Menthol Cream work to stop itching?

Menthol activates TRPM8 cold-sensitive receptors in the skin, generating a cooling sensation that temporarily overrides the itch signal being sent to the brain. This counter-stimulation effect is well recognised in dermatology as a non-steroidal way to break the itch-scratch cycle. The aqueous cream base also provides light moisturisation to help soothe dry, irritated skin.

How do I apply Dermacool 5% Menthol Cream step by step?

Clean and gently pat dry the affected area, then apply a thin layer of cream using clean fingertips, smoothing it in the direction of hair growth. Wash your hands after application unless your hands are the area being treated. Repeat as needed throughout the day, avoiding broken or infected skin.

How often can I apply Dermacool 5% Menthol Cream each day?

Dermacool can be applied as often as needed to relieve itching, and there is no strict maximum number of daily applications for adults. However, if you find you need to apply it very frequently without improvement, this may suggest the underlying skin condition needs further assessment. Speak to your pharmacist or GP if symptoms are not settling within 7 days.

Can children use Dermacool 5% Menthol In Aqueous Cream?

Dermacool 5% is generally considered suitable for children over 2 years of age, but you should always consult a pharmacist or GP before using a 5% menthol product on a young child, as lower-strength options may be more appropriate. Do not use on infants under 2 years without medical advice. If your child has eczema, the NHS recommends discussing emollient and antipruritic choices with a healthcare professional.

What are the side effects of Dermacool 5% Menthol Cream?

Most people tolerate Dermacool well, and the cooling sensation itself is an expected part of how it works rather than a side effect. Uncommon reactions can include localised skin irritation, redness, or a burning feeling, particularly on sensitive or broken skin. If you develop a rash, increased swelling, or any sign of an allergic reaction, stop use immediately and contact your pharmacist.

Can I use Dermacool 5% Menthol Cream on my face?

You should avoid applying Dermacool near the eyes, mouth, or any mucous membranes, as menthol can cause significant irritation in these areas. If you need to treat itching on facial skin, speak to your pharmacist first — they may recommend a lower-strength product or an alternative preparation. Always keep the cream well away from the eye area during application.

Is Dermacool 5% Menthol Cream safe to use during pregnancy?

There is limited specific safety data on topical menthol use during pregnancy, so it is always best to consult your GP or midwife before using Dermacool if you are pregnant or breastfeeding. Many pregnant women experience itchy skin, and a healthcare professional can advise on the safest options for your individual circumstances. Do not self-treat persistent or widespread itching in pregnancy without medical assessment.

Who is eligible to use Dermacool 5% Menthol In Aqueous Cream?

Dermacool 5% is suitable for most adults and children over 2 years who experience itching from eczema, dermatitis, psoriasis, or insect bites. It is not suitable for use on broken, infected, or weeping skin, or for people with a known allergy to menthol or any ingredient in the cream. If you have a complex skin condition or are using other topical treatments, check with your pharmacist before starting. You can also browse our creams and ointments collection for related products.

What happens if I accidentally apply too much Dermacool cream?

Applying more cream than needed is unlikely to cause serious harm, but it may increase the risk of skin irritation or a more intense cooling sensation than expected. If you accidentally get the cream in your eyes or mouth, rinse thoroughly with water and seek medical advice if irritation persists. There is no known systemic toxicity from topical use at this concentration when applied as directed.

What are the alternatives to Dermacool 5% Menthol Cream?

Alternatives include lower-strength menthol creams such as Dermacool 1% or 2%, which may suit those with more sensitive skin. Other antipruritic options include crotamiton cream or calamine lotion, depending on the cause of the itch. Your pharmacist can help you choose the most appropriate product for your specific skin condition and history.

How long can I use Dermacool 5% Menthol Cream for?

You can use Dermacool for as long as your symptoms require, but if itching has not improved after 7 days of regular use, it is worth speaking to a pharmacist or GP to investigate the underlying cause. Long-term use of aqueous cream as a leave-on emollient has been associated with skin reactions in some people with eczema, so your pharmacist may suggest switching to an alternative emollient base if you plan to use it continuously. Regular review of your skin care routine is always a good idea.

Can I use Dermacool 5% Menthol Cream alongside a topical steroid?

Yes, but you should apply them at different times of day rather than mixing them together or applying one immediately after the other. Applying an emollient and a topical steroid simultaneously can dilute the steroid and reduce its effectiveness. The NHS recommends leaving at least 30 minutes between applying an emollient and a topical steroid to the same area of skin.

Is Dermacool 5% Menthol Cream a steroid?

No — Dermacool contains no steroids whatsoever. Its active ingredient is menthol, which works by stimulating cooling receptors in the skin rather than by suppressing inflammation. This makes it a useful option for people who want to avoid or reduce their use of topical corticosteroids, though it does not replace them when inflammation is the primary issue. If you are managing eczema or psoriasis, your pharmacist can help you build a complete skin care plan. You can also explore our skin care range for further options.

What does the latest research say about menthol cream for itching?

Research into topical menthol continues to support its use as an antipruritic agent, with studies confirming its action on TRPM8 receptors as the primary mechanism for itch relief. Clinical interest has grown in menthol as a non-pharmacological option for managing chronic itch in conditions such as atopic dermatitis and uraemic pruritus. While it is not a cure, it remains a well-tolerated and widely recommended symptomatic treatment in UK dermatology practice.

How Should You Use Dermacool 5% Menthol In Aqueous Cream?

Dermacool 5% Menthol In Aqueous Cream is for external use only. Always apply it to clean, intact skin and avoid any areas that are broken, infected, or weeping. Follow these steps each time you use it:

Avoid contact with the eyes, mouth, and mucous membranes at all times. If accidental contact occurs, rinse the area thoroughly with clean water.

What Is the Correct Dose of Dermacool 5% Menthol In Aqueous Cream?

There is no fixed single dose for Dermacool — the amount you use will depend on the size of the area being treated. Apply a thin layer sufficient to cover the affected skin. The table below provides general guidance:

When Is the Best Time to Use Dermacool 5% Menthol In Aqueous Cream?

You can apply Dermacool whenever itching becomes uncomfortable — there is no fixed time of day. Many people find it particularly helpful at night, when itch tends to worsen and can disrupt sleep. If you are also using a topical steroid, apply Dermacool at a different time of day — the NHS recommends leaving at least 30 minutes between applying an emollient and a topical corticosteroid to the same area, to avoid diluting the steroid's effect.

Applying the cream after a bath or shower, when the skin is clean and slightly warm, can also help it absorb more effectively and provide longer-lasting comfort.

How Long Can You Use Dermacool 5% Menthol In Aqueous Cream For?

Dermacool can be used for as long as your symptoms require. However, if your itching has not improved after 7 days of regular use, you should consult a pharmacist or GP to investigate the underlying cause rather than continuing to self-treat. Long-term use of aqueous cream as a leave-on emollient has been associated with skin reactions in some people with eczema, so your pharmacist may suggest switching to an alternative emollient base if you plan to use it continuously over a prolonged period.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Based on 4 reviews
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L
Laura Fulcher

looks OK .Havent tried it yet. couldnt get it anywhwere except online. . wasw recommended by the hospice.

A
Anonymous

Good product thank you

j
julie

Fab cream fast postage

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Anonymous

Lovely cooling cream, dies what it says but quite expensive for quantity though

What Are the Most Common Side Effects of Dermacool 5% Menthol Cream?

Most people who use Dermacool 5% Menthol In Aqueous Cream tolerate it well. The cooling or tingling sensation you feel on application is an expected part of how the product works — it is not a side effect. That said, some people do experience mild reactions, particularly when first using a 5% menthol concentration.

  • Mild tingling or cooling sensation at the application site
  • Temporary skin redness (erythema) at the treated area
  • A slight warming sensation following the initial cooling effect

These effects are generally short-lived and resolve on their own. If they persist or feel uncomfortable, reduce the frequency of application and speak to your pharmacist.

What Are the Less Common Side Effects of Dermacool 5% Menthol Cream?

Less commonly, some individuals — particularly those with sensitive or already-compromised skin — may experience more noticeable reactions. These are not typical but are worth being aware of before you start using the product.

  • Skin irritation or a burning sensation, especially on thin or sensitive skin
  • Dryness or peeling at the application site with prolonged use
  • Worsening of eczema symptoms in individuals who are sensitive to the aqueous cream base — this has been documented in clinical literature and is worth monitoring
  • Contact dermatitis — an allergic skin reaction to menthol or another ingredient in the formulation

If you notice any of these reactions, stop using the cream and consult your pharmacist. They may recommend a lower-strength menthol product or an alternative antipruritic preparation.

What Are the Serious Side Effects of Dermacool 5% Menthol Cream?

Serious side effects from topically applied menthol at this concentration are rare. However, you should seek urgent medical attention if you experience any of the following after applying Dermacool:

  • Significant swelling of the skin, face, lips, or throat
  • Blistering or severe skin breakdown at the application site
  • Difficulty breathing or signs of a systemic allergic reaction (anaphylaxis)

These reactions are very uncommon but represent a medical emergency. Do not wait — call 999 or go to your nearest A&E department immediately if you suspect a serious allergic reaction.

What Should You Do If You Experience Side Effects of Dermacool?

If you develop any side effect that concerns you, the first step is to stop applying the cream to the affected area. Rinse the skin gently with cool water if there is irritation. For mild reactions, your pharmacist is the best first point of contact — they can assess whether the reaction is likely to be related to the menthol, the aqueous cream base, or another factor entirely. You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Do not simply switch to a different product without guidance, as some reactions may indicate a broader skin sensitivity that needs proper assessment.

Can Dermacool 5% Menthol Cream Interact With Other Medicines?

No significant drug interactions are currently known for topically applied menthol at this concentration. However, you should avoid applying Dermacool at the same time as other topical medicines — including topical steroids, antifungals, or antibiotics — to the same area of skin. Applying two topical products simultaneously can dilute the effectiveness of both and may increase the risk of skin reactions. Always leave adequate time between applications and seek pharmacist advice if you are using multiple topical treatments for the same area.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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