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Dermacool 2% Menthol In Aqueous Cream

Dermacool 2% Menthol In Aqueous Cream

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  • ✔️ Relieves itchy skin caused by eczema and dermatitis
  • ✔️ Cooling menthol sensation reduces the urge to scratch
  • ✔️ Moisturises and soothes dry, irritated skin simultaneously
  • ✔️ Suitable for adults and children with pruritic skin conditions
  • ✔️ No prescription needed — available over the counter

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What Is Menthol in Aqueous Cream Used For?

 

If you've ever dealt with persistent, maddening itching — whether from eczema, an allergic reaction, or dry skin — you'll know how disruptive it can be. Menthol in aqueous cream is a well-established topical preparation used to relieve pruritus (the medical term for itching) associated with a range of skin conditions. Dermacool 2% Menthol In Aqueous Cream contains 2% menthol in a simple, non-greasy aqueous cream base, making it a practical option for everyday use on irritated or itchy skin. It's available over the counter, meaning you don't need a prescription to get started.

Itchy skin is one of the most common complaints seen in UK pharmacies. The NHS recognises that conditions such as eczema, contact dermatitis, and allergic skin reactions can cause significant discomfort, and topical preparations like this one are often recommended as part of a broader skin management plan. If you're exploring options for skin care products that are gentle yet effective, Dermacool 2% is worth considering.

 

How Does Dermacool 2% Menthol Cream Work?

 

The mechanism behind menthol's itch-relieving effect is genuinely interesting. Rather than numbing the skin in the traditional sense, menthol works by activating specific cold-sensitive receptors in the skin — primarily TRPM8 receptors. This triggers a cooling sensation that effectively competes with and overrides the itch signal being sent to the brain. It's a bit like distracting your nervous system with a different, more tolerable sensation.

  • Menthol binds to TRPM8 cold receptors in peripheral nerve fibres
  • This produces a localised cooling sensation on the skin surface
  • The cooling signal competes with pruritic (itch) signals travelling to the brain
  • The aqueous cream base simultaneously hydrates and softens the skin barrier
  • Together, these actions reduce the urge to scratch, helping to prevent further skin damage

The aqueous cream base itself plays a supporting role. Dry skin is a major trigger for itching, and keeping the skin moisturised helps to restore the skin's natural barrier function — something particularly relevant for people managing eczema or psoriasis.

 

Who Should Use Dermacool 2% Menthol Cream?

 

This cream is suitable for adults and children who experience itching related to a variety of skin conditions. It's particularly useful when the itch is the primary symptom you want to address, rather than inflammation or infection. That said, it's not a treatment for the underlying cause — it manages the symptom while your skin heals or while other treatments take effect.

Dermacool 2% may be appropriate for people with:

  • Eczema (atopic dermatitis) causing dry, itchy skin
  • Contact dermatitis or allergic skin reactions
  • Pruritus associated with psoriasis
  • Generalised dry skin causing itching in older adults

It is not suitable for use on broken, infected, or severely inflamed skin. If you're unsure whether it's right for your condition, a quick conversation with your pharmacist is always a sensible first step. You might also find it helpful to browse our range of creams and ointments for other topical options.

 

How Does Dermacool 2% Compare to Other Menthol Creams?

 

Feature Dermacool 2% Menthol In Aqueous Cream Dermacool 1% Menthol In Aqueous Cream
Menthol concentration 2% 1%
Cooling intensity Moderate to strong Mild to moderate
Suitable for sensitive skin Use with caution More suitable for sensitive skin
OTC availability Yes Yes

 

Is Dermacool 2% Menthol Cream Safe to Store at Home?

 

Storage is straightforward. Keep the cream below 25°C, away from direct sunlight, and out of reach of children. Do not freeze it. Once opened, check the product's in-use expiry guidance on the packaging — most aqueous cream preparations should be used within a reasonable period after opening to maintain their quality and hygiene. Menthol in aqueous cream is a stable formulation, but like all topical products, it should be discarded if it changes in appearance, smell, or texture.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Dermacool 2% Menthol In Aqueous Cream specifications
Treatment category Antipruritic / Emollient
Mechanism of action TRPM8 receptor activation producing cooling sensation to relieve itch
Effective for Itching associated with eczema, dermatitis, psoriasis, and dry skin
Suitable for Adults and children (consult pharmacist for young children)
Active ingredient Menthol 2% w/w
Strengths 2% menthol
UK classification General Sale List (GSL)
Drug class Antipruritic / Topical analgesic
Preparation Cream
Route of administration Topical (applied to skin)

Specifications of Dermacool 2% Menthol In Aqueous Cream

 

What Is Dermacool 2% Menthol In Aqueous Cream and What Is It Used For?

 

Dermacool 2% Menthol In Aqueous Cream is a topical antipruritic preparation containing 2% menthol in an aqueous (water-based) cream base. It is used to relieve itching of the skin caused by conditions such as eczema, contact dermatitis, psoriasis, and other pruritic skin disorders. The menthol provides a cooling sensation that helps to reduce the urge to scratch, while the cream base helps to moisturise and soothe the skin. It is available without a prescription and is classified as a General Sale List (GSL) medicine in the UK.

 

What Do You Need to Know Before Using Dermacool 2% Menthol Cream?

 

Before applying this cream, there are some important things to be aware of. It is not suitable for everyone, and certain conditions or circumstances mean you should seek advice before use.

Do not use this cream if you:

  • Are allergic to menthol, aqueous cream, or any of the other ingredients
  • Have broken, infected, or open skin at the site of application
  • Have severely inflamed or weeping skin lesions
  • Are applying it near the eyes, mouth, or mucous membranes

Take care and speak to your pharmacist or GP if you:

  • Are pregnant or breastfeeding — while topical menthol is generally considered low risk, always check with a healthcare professional
  • Are using this on a young child or infant
  • Have a known sensitivity to cooling agents or topical preparations
  • Are using other topical medicines on the same area of skin

Known drug interactions:

  • No significant drug interactions are currently documented for topical menthol at this concentration
  • Avoid using alongside other topical preparations on the same skin area without pharmacist guidance, as this may affect absorption or cause irritation

If you experience any allergic skin reactions — such as hives, swelling, or worsening redness — stop using the cream immediately and seek medical advice. People managing skin conditions alongside allergies may also find it useful to explore our allergy and hay fever range for complementary support.

 

How Should You Use Dermacool 2% Menthol Cream?

 

Using this cream correctly will help you get the most benefit from it. Always follow the instructions on the packaging or as directed by your pharmacist.

  1. Wash and dry your hands thoroughly before applying the cream
  2. Ensure the affected skin area is clean and dry
  3. Apply a thin, even layer of cream to the itchy or irritated area
  4. Gently smooth the cream into the skin — do not rub vigorously
  5. Wash your hands again after application, unless your hands are the area being treated
  6. Avoid contact with eyes, mouth, and broken skin
  7. Repeat as needed, following the dosage guidance below
Indication Age Group Dose Frequency
Itching from eczema or dermatitis Adults Thin layer to affected area 2–3 times daily or as needed
Itching from psoriasis or dry skin Adults Thin layer to affected area 2–3 times daily or as needed
Pruritic skin conditions Children (consult pharmacist) Small amount to affected area As directed by pharmacist or GP

 

What Are the Possible Side Effects of Dermacool 2% Menthol Cream?

 

Like all medicines, Dermacool 2% Menthol In Aqueous Cream can cause side effects, although not everyone will experience them. Most people tolerate it well.

Common side effects:

  • Mild burning or stinging sensation immediately after application
  • Temporary redness at the application site
  • Skin dryness if used very frequently without additional moisturisation

Less common side effects:

  • Contact dermatitis (allergic reaction to an ingredient in the cream)
  • Increased skin sensitivity or irritation with prolonged use
  • Rash or urticaria (hives) in individuals with menthol sensitivity

If you notice any worsening of your skin condition, or if you develop signs of an allergic reaction such as swelling, difficulty breathing, or widespread rash, stop using the cream and seek urgent medical attention. The NHS advises that any new or worsening skin symptoms should be assessed by a healthcare professional.

 

How Should You Store Dermacool 2% Menthol Cream?

 

Correct storage helps to maintain the quality and safety of the product. Follow these guidelines to keep your cream in good condition. You can also browse our full range of skin care products for additional support alongside this cream.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze
  • Keep the lid tightly closed when not in use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the packaging
  • Discard if the cream changes in colour, smell, or consistency

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Dermacool 2% Menthol In Aqueous Cream online in the UK?

You can order Dermacool 2% Menthol In Aqueous Cream directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter product, so no consultation is required. Simply add it to your basket and it will be dispatched to your door.

How does Dermacool 2% Menthol In Aqueous Cream work in the body?

Menthol activates cold-sensitive TRPM8 receptors in the skin, producing a cooling sensation that competes with and overrides the itch signal being sent to the brain. This is why you feel a cooling effect rather than numbness when you apply it. The aqueous cream base also helps to hydrate and support the skin's natural barrier, which is particularly helpful in conditions like eczema.

How do I apply Dermacool 2% Menthol Cream step by step?

Wash and dry your hands, then apply a thin layer of cream to the clean, dry affected area and smooth it in gently. Avoid broken skin, eyes, and mucous membranes, and wash your hands again after application unless your hands are the area being treated. Repeat two to three times daily or as needed.

How often should I apply Dermacool 2% Menthol Cream each day?

For most adults, applying the cream two to three times daily to the affected area is appropriate, or as directed by your pharmacist or GP. There is no strict fixed schedule — you can apply it when itching flares up, as the relief is relatively prompt. Avoid applying excessively large amounts, as this does not increase the benefit and may increase the risk of skin irritation.

Can children use Dermacool 2% Menthol In Aqueous Cream?

Dermacool 2% menthol cream can be used in children, but you should consult a pharmacist or GP before applying it to young children or infants, as menthol can occasionally cause skin sensitivity in younger age groups. For older children with eczema or itchy skin, a healthcare professional can advise on the appropriate amount and frequency. Always keep the cream away from a child's face, eyes, and mouth.

What are the side effects of Dermacool 2% Menthol Cream and how do I manage them?

The most common side effects are a mild burning or stinging sensation and temporary redness at the application site, both of which usually settle quickly. Less commonly, some people may develop contact dermatitis or increased skin sensitivity, particularly with prolonged use. If you notice worsening irritation, a rash, or signs of an allergic reaction, stop using the cream and speak to your pharmacist or GP.

Is Dermacool 2% Menthol Cream suitable for use during pregnancy?

Topical menthol at low concentrations is generally considered low risk during pregnancy, but you should always check with your GP or midwife before using any new medicine while pregnant. The same applies if you are breastfeeding, particularly if you are applying the cream to areas near the chest. Your healthcare professional can help you weigh up the benefits and any potential risks.

Can I use Dermacool 2% Menthol Cream on my face?

Use on the face should be approached with caution, and you should always avoid contact with the eyes, nostrils, and mouth. If you have itchy skin on the face related to a condition like eczema or contact dermatitis, speak to your pharmacist before applying, as they can advise on whether this product is appropriate for facial use. There may be more suitable alternatives for sensitive facial skin.

What happens if I accidentally get Dermacool 2% Menthol Cream in my eyes?

If the cream comes into contact with your eyes, rinse them immediately and thoroughly with clean, lukewarm water for several minutes. Do not rub your eyes, as this can worsen irritation. If discomfort, redness, or blurred vision persists after rinsing, seek medical attention promptly.

How long can I use Dermacool 2% Menthol Cream for?

You can use Dermacool 2% menthol cream for as long as your symptoms persist, but if your skin condition does not improve after two weeks of regular use, you should seek advice from a GP or pharmacist. Long-term use without review is not recommended, as persistent itching may indicate an underlying condition that requires further investigation or a different treatment approach. Our skin care range includes other options that may complement your routine.

What is the difference between Dermacool 1% and 2% Menthol Cream?

The 2% formulation contains a higher concentration of menthol than the 1% version, which generally produces a more pronounced cooling and antipruritic effect. The 1% version may be more appropriate for people with sensitive skin or those new to menthol-based preparations. If you are unsure which strength is right for you, your pharmacist can help you decide based on your skin type and the severity of your symptoms.

Can I use Dermacool 2% Menthol Cream alongside other skin treatments?

You can generally use Dermacool 2% alongside other topical treatments, but you should avoid applying multiple creams to exactly the same area at the same time, as this can affect how each product is absorbed. If you are using prescribed topical steroids or other medicated creams, ask your pharmacist about the best order and timing of application. Spacing applications by at least 30 minutes is often recommended.

What are the alternatives to Dermacool 2% Menthol Cream for itchy skin?

Alternatives for itchy skin include other antipruritic creams, emollients, and in some cases antihistamine tablets for allergy-related itching. You can explore our creams and ointments collection for a range of topical options. Your pharmacist or GP can advise on the most appropriate treatment based on the cause of your itching.

Is there any research supporting the use of menthol cream for itching?

Yes — menthol's antipruritic effect is supported by its well-documented action on TRPM8 cold receptors in the skin, and it has been used in topical preparations for itch relief for many decades. Clinical use is recognised in UK pharmacy practice, and menthol-based preparations are listed in the British National Formulary (BNF) as antipruritic agents. While large-scale randomised controlled trials are limited, the mechanism of action is well understood and the safety profile at 2% concentration is established.

Does Dermacool 2% Menthol Cream treat the cause of eczema or just the itch?

Dermacool 2% menthol cream treats the symptom of itching rather than the underlying cause of eczema or other skin conditions. It provides symptomatic relief by cooling the skin and reducing the urge to scratch, which in turn helps to prevent the itch-scratch cycle that can worsen skin damage. For managing the underlying condition, you should follow the treatment plan recommended by your GP or dermatologist, which may include emollients and topical steroids.

How Should You Use Dermacool 2% Menthol In Aqueous Cream?

Applying Dermacool 2% correctly ensures you get the most relief from each application. Always read the label before use, and if you have any doubts about whether this product is right for your skin condition, speak to your pharmacist first.

If you are applying the cream to a large area of skin, use the minimum amount needed to cover the affected region. More is not necessarily better — a thin layer is sufficient to deliver the cooling, antipruritic effect.

What Is the Correct Dose of Dermacool 2% Menthol In Aqueous Cream?

There is no single fixed dose for topical creams like this one, as the amount used depends on the size of the affected area and the severity of symptoms. The table below provides general guidance based on indication and age group.

When Is the Best Time to Use Dermacool 2% Menthol In Aqueous Cream?

There is no single "best" time of day to apply this cream — it works on demand, meaning you can apply it whenever itching flares up. Many people find it particularly helpful after bathing or showering, when the skin is clean and slightly warm, as this can help the cream absorb more evenly. Applying it before bed may also help to reduce overnight scratching, which is a common problem for people with eczema.

If you are using other topical treatments such as emollients or prescribed steroid creams, space your applications by at least 30 minutes to allow each product to be absorbed properly before applying the next.

How Long Can You Use Dermacool 2% Menthol In Aqueous Cream For?

Dermacool 2% can be used for as long as your symptoms require it, and there is no strict maximum duration for short-term use. However, if your itching has not improved after two weeks of regular application, this is a signal to seek advice from your GP or pharmacist, as the underlying cause may need further investigation or a different treatment approach.

Prolonged use without review is not recommended. If you find yourself relying on the cream daily over an extended period, a healthcare professional can help you identify whether a longer-term management plan — such as regular emollient use or treatment of an underlying skin condition — would be more appropriate.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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brenda

Ot really helps sore legs.

What Are the Most Common Side Effects of Dermacool 2% Menthol In Aqueous Cream?

Most people who use Dermacool 2% Menthol In Aqueous Cream tolerate it well, and serious side effects are uncommon. The most frequently reported effects are mild and localised to the area of application, typically settling within a few minutes of applying the cream.

  • Mild burning or stinging sensation immediately after application
  • Temporary redness or flushing of the skin at the treated site
  • A pronounced cooling sensation that some people find uncomfortable at first
  • Mild skin dryness if the cream is used very frequently without additional moisturisation

What Are the Less Common Side Effects of Dermacool 2% Menthol Cream?

Less commonly, some individuals may experience a more significant skin reaction. These effects are more likely in people with sensitive skin, a history of skin allergies, or those using the cream on large areas of the body over a prolonged period.

  • Contact dermatitis — an allergic or irritant reaction causing redness, itching, and blistering
  • Increased skin sensitivity or heightened irritation with repeated use
  • Urticaria (hives) in individuals with a sensitivity to menthol
  • Skin peeling or flaking at the application site

What Are the Serious Side Effects of Dermacool 2% Menthol Cream?

Serious side effects from topical menthol at 2% concentration are rare. However, you should be aware of the signs of a systemic allergic reaction, which — though very uncommon with topical preparations — can occasionally occur in highly sensitive individuals.

Seek urgent medical attention if you experience any of the following after applying the cream:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Widespread rash or hives spreading beyond the application site
  • Dizziness or feeling faint

What Should You Do If You Experience Side Effects of Dermacool 2% Menthol Cream?

If you experience mild side effects such as stinging or temporary redness, these usually resolve on their own within a few minutes and do not require you to stop using the cream. However, if the irritation is persistent, worsening, or causing significant discomfort, stop applying the cream and speak to your pharmacist or GP before continuing.

For any signs of an allergic reaction — particularly swelling, widespread rash, or breathing difficulties — stop use immediately and seek emergency medical help. Do not wait to see if symptoms improve on their own in these circumstances.

Can Dermacool 2% Menthol Cream Interact With Other Medicines?

No significant drug interactions are currently documented for topical menthol at 2% concentration. However, applying multiple topical preparations to the same area of skin at the same time is generally not recommended, as this can affect how each product is absorbed and may increase the risk of skin irritation. If you are using prescribed topical medicines such as corticosteroids or calcineurin inhibitors alongside this cream, ask your pharmacist about the appropriate order and timing of application to avoid any potential interference.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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