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Cetaphil Moisturising Cream - 450g

Cetaphil Moisturising Cream - 450g

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  • ✔️ Restores and maintains the skin's natural moisture barrier
  • ✔️ Fragrance-free and non-comedogenic — safe for sensitive skin
  • ✔️ Clinically recommended for eczema, psoriasis, and dry skin
  • ✔️ Suitable for use on both face and body daily
  • ✔️ Large 450g tub provides long-lasting supply for regular use

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What Is Cetaphil Moisturising Cream and Who Is It For?

 

If you have dry, sensitive, or eczema-prone skin, finding a moisturiser that actually works — without causing irritation — can feel like an endless search. Cetaphil moisturising cream has been a dermatologist-recommended staple for decades, and for good reason. This 450g tub offers a rich, fragrance-free emollient formula that helps restore and maintain the skin's natural moisture barrier. It's suitable for everyday use on both the face and body, and it's available over the counter without a prescription. You can explore the full range of skin care products at Cured Pharmacy to find the right option for your needs.

The NHS recognises emollients as a cornerstone of managing dry skin conditions, including eczema and psoriasis. Regular, consistent moisturising helps reduce flare-ups, soothe irritation, and prevent the skin from cracking or becoming inflamed. At just £13.59 for a 450g tub, this is a cost-effective option for long-term skin care.

 

How Does Cetaphil Moisturising Cream Work on Dry Skin?

 

Emollients like cetaphil moisturising cream work by forming a protective layer over the skin's surface, reducing water loss and softening the outer layers of skin. Here's how the mechanism breaks down:

  • Humectants (glycerin): Draw moisture from the environment and deeper skin layers into the outer skin, increasing hydration.
  • Emollients (sweet almond oil, sunflower seed oil): Fill in the gaps between skin cells, smoothing and softening the skin's texture.
  • Occlusives: Create a semi-permeable barrier on the skin surface to slow transepidermal water loss (TEWL).
  • Skin-conditioning agents: Help maintain the integrity of the skin barrier over time with repeated use.

The formula is non-comedogenic, meaning it won't block pores, and it contains no added fragrance or colourants — both common triggers for sensitive skin reactions.

 

Who Should Use Cetaphil Moisturising Cream?

 

This cream is designed for anyone with dry to very dry skin, but it's particularly well-suited to those with chronic skin conditions. The NHS recommends emollients for a wide range of patients, and this product fits neatly into that guidance.

It may be especially helpful if you:

  • Have eczema (atopic dermatitis) and need a daily leave-on emollient
  • Suffer from psoriasis and require regular skin hydration between treatments
  • Have sensitive skin that reacts to fragranced or heavily formulated products
  • Are looking for a gentle moisturiser safe for use on the face and body
  • Need a moisturiser suitable for use during or after medical skin treatments

 

How Does Cetaphil Moisturising Cream Compare to Similar Emollients?

 

Feature Cetaphil Moisturising Cream 450g E45 Cream 500g
Fragrance-free Yes Yes
Key ingredients Glycerin, sweet almond oil, sunflower seed oil White soft paraffin, light liquid paraffin, anhydrous lanolin
Suitable for face Yes, non-comedogenic Yes, but heavier texture
Suitable for eczema Yes Yes
Paraben-free Yes No (contains parabens)

 

Is Cetaphil Moisturising Cream Suitable for Long-Term Use?

 

Yes. Cetaphil moisturising cream is formulated for daily, long-term use and does not contain steroids or active pharmaceutical ingredients that would require cycling or breaks in treatment. Because it works purely as an emollient and skin-barrier support, it can be used indefinitely as part of your daily skin care routine. If you're managing a condition like eczema alongside this cream, you may also want to browse creams and ointments for complementary treatments.

Store the product below 25°C, away from direct sunlight and out of reach of children. Do not use past the expiry date printed on the tub.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Cetaphil Moisturising Cream 450g specifications
Treatment category Emollient / Moisturiser
Mechanism of action Forms a protective barrier; reduces transepidermal water loss; hydrates via humectants
Effective for Dry skin, sensitive skin, eczema, psoriasis
Suitable for Adults, children (consult GP for infants); face and body use
Active ingredients Glycerin, Sweet Almond Oil, Sunflower Seed Oil
Pack size 450g
UK classification General Sale (GSL)
Drug class Emollient
Preparation Cream
Route of administration Topical

Specifications of Cetaphil Moisturising Cream 450g

 

What Is Cetaphil Moisturising Cream and What Is It Used For?

 

Cetaphil Moisturising Cream is a topical emollient used to relieve and manage dry, rough, and sensitive skin. It is suitable for use on the face and body and is commonly recommended for people with eczema, psoriasis, ichthyosis, and other dry skin conditions. The NHS advises that emollients should be applied regularly — even when skin appears to be improving — to maintain the skin barrier and prevent flare-ups. This cream is available over the counter and does not require a prescription.

The 450g tub is designed for frequent, generous application. Unlike lighter lotions, the cream texture provides longer-lasting hydration and is particularly useful for areas of very dry or thickened skin such as elbows, knees, and heels.

 

What Do You Need to Know Before Using Cetaphil Moisturising Cream?

 

Cetaphil Moisturising Cream is generally very well tolerated, but there are a few things to be aware of before you start using it.

Do not use this product if you:

  • Are allergic to any of the listed ingredients, including sweet almond oil or sunflower seed oil
  • Have a known nut allergy — sweet almond oil is derived from almonds; consult your pharmacist or GP before use
  • Have an infected area of skin — emollients should not be applied to actively infected or broken skin without medical advice

Warnings and precautions:

  • Avoid contact with the eyes; if contact occurs, rinse thoroughly with water
  • Keep away from open flames — emollient creams can make fabric flammable if they soak into dressings or clothing
  • Discontinue use and seek advice if a rash, redness, or worsening of skin condition occurs
  • For use on children under 2 years, consult a GP or pharmacist first

Known drug interactions:

  • No significant drug interactions are known for topical emollients of this type
  • If using alongside topical corticosteroids, apply the emollient first and allow it to absorb before applying the steroid cream

 

How Should You Use Cetaphil Moisturising Cream?

 

Using an emollient correctly makes a real difference to how effective it is. The NHS recommends applying emollients generously and frequently — not just when skin feels tight or uncomfortable. Here's how to get the most from this product:

  1. Wash and gently pat your skin dry with a soft towel — do not rub.
  2. Scoop out the cream using a clean spatula or spoon to avoid contaminating the tub.
  3. Apply a generous amount to the affected area using smooth, downward strokes in the direction of hair growth.
  4. Allow the cream to absorb for a few minutes before dressing.
  5. Reapply throughout the day as needed, especially after washing hands or bathing.
Indication Age Group Dose Frequency
Dry / sensitive skin Adults and children over 2 Apply liberally to affected areas 2–3 times daily or as needed
Eczema management Adults and children over 2 Apply generously At least 3 times daily
Post-wash moisturising All ages (GP advice for under 2) Apply to damp skin after bathing After every wash

If you're also managing a skin condition such as eczema, you may find it helpful to browse creams and ointments for additional treatment options available at Cured Pharmacy.

 

What Are the Possible Side Effects of Cetaphil Moisturising Cream?

 

Cetaphil Moisturising Cream is well tolerated by most people. Side effects are uncommon, but as with any topical product, reactions can occasionally occur.

Common side effects:

  • Mild stinging or tingling immediately after application, particularly on broken or very dry skin
  • Temporary greasiness or heaviness on the skin surface

Less common side effects:

  • Contact dermatitis — redness, itching, or a rash at the site of application
  • Allergic reaction to one of the ingredients (e.g. sweet almond oil in those with nut sensitivities)
  • Folliculitis (inflammation of hair follicles) if the cream is applied against the direction of hair growth

If you experience any signs of a serious allergic reaction — including swelling of the face, lips, or throat, or difficulty breathing — stop using the product immediately and seek emergency medical help.

 

How Should You Store Cetaphil Moisturising Cream?

 

Correct storage helps maintain the product's quality and safety throughout its shelf life. For families with young children, it's also worth keeping all skin care products out of reach as a general precaution — you can find more child-appropriate options in the baby and toddler section at Cured Pharmacy.

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Do not freeze
  • Keep the lid tightly closed when not in use
  • Do not use after the expiry date printed on the tub
  • Keep out of reach and sight of children
  • Use a clean spatula to remove product from the tub to prevent contamination

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Cetaphil Moisturising Cream online in the UK?

You can buy Cetaphil Moisturising Cream 450g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £13.59. It is available without a prescription and can be ordered for home delivery. Browse the full skin care range for more options.

What are the ingredients in Cetaphil Moisturising Cream?

Cetaphil Moisturising Cream contains glycerin, sweet almond oil, and sunflower seed oil as key moisturising ingredients, alongside a blend of emollients and skin-conditioning agents. It is free from added fragrance, parabens, and colourants. This makes it particularly suitable for people with sensitive or reactive skin.

Is Cetaphil Moisturising Cream good for eczema?

Yes — cetaphil moisturising cream is widely used for eczema-prone skin because it helps restore the skin's moisture barrier and reduces dryness and irritation. The NHS recommends regular emollient use as a core part of eczema management, even during periods when the skin appears clear. It should be used alongside any prescribed treatments, not as a replacement for them.

Can I use Cetaphil Moisturising Cream on my face?

Yes, Cetaphil Moisturising Cream is non-comedogenic, meaning it won't block pores, and is suitable for use on the face as well as the body. Its gentle, fragrance-free formula makes it appropriate for sensitive facial skin, including around the nose and cheeks. Many dermatologists recommend it as a daily facial moisturiser for those with dry or reactive skin.

How often should I apply Cetaphil Moisturising Cream?

Apply Cetaphil Moisturising Cream two to three times daily, or more frequently if your skin is very dry. The NHS advises applying emollients generously and regularly — particularly after bathing while the skin is still slightly damp — to lock in moisture effectively. Consistency is key; occasional use is far less effective than a regular routine.

Is Cetaphil Moisturising Cream safe for babies and children?

Cetaphil Moisturising Cream is generally considered suitable for children over 2 years of age, but you should consult your GP or pharmacist before applying any emollient to an infant's skin. For baby-specific products, you can also explore the baby and toddler range at Cured Pharmacy. Always patch test on a small area of skin first.

Can I use Cetaphil Moisturising Cream during pregnancy?

Cetaphil Moisturising Cream is generally considered safe to use during pregnancy as it is a topical emollient with no known systemic absorption. Many pregnant women use it to manage dry or itchy skin, which is common during pregnancy. Always check with your midwife or GP if you have any specific concerns about ingredients.

What is the difference between Cetaphil Moisturising Cream and Cetaphil Moisturising Lotion?

The cream is thicker and more occlusive, making it better suited for very dry, eczema-prone, or rough skin that needs intensive hydration. The lotion has a lighter, more fluid consistency that absorbs quickly and is better suited to normal to dry skin or for use in warmer weather. If your skin is severely dry, the cream is generally the more effective choice.

How do I apply Cetaphil Moisturising Cream step by step?

Start by gently patting your skin dry after washing — avoid rubbing. Use a clean spatula to scoop out the cream, then apply it in smooth, downward strokes following the direction of hair growth to reduce the risk of folliculitis. Allow it to absorb for a few minutes before getting dressed.

What should I do if Cetaphil Moisturising Cream causes a reaction?

If you notice redness, itching, or a rash after applying the cream, stop using it immediately and wash the area with cool water. Contact your pharmacist or GP for advice, particularly if the reaction spreads or worsens. A patch test on a small area of skin before first use is always a sensible precaution.

Can Cetaphil Moisturising Cream be used alongside steroid creams?

Yes — emollients like Cetaphil Moisturising Cream are often used alongside topical corticosteroids as part of an eczema or psoriasis treatment plan. Apply the emollient first and allow it to absorb for at least 30 minutes before applying the steroid cream. This approach is consistent with NHS guidance on emollient use in skin conditions.

Is Cetaphil Moisturising Cream suitable for psoriasis?

Yes, regular emollient use is recommended by the NHS as part of psoriasis management to reduce scaling, dryness, and discomfort. Cetaphil Moisturising Cream's gentle, fragrance-free formula makes it a practical choice for daily use on psoriasis-affected skin. It does not treat the underlying condition but helps manage symptoms effectively.

How long can I use Cetaphil Moisturising Cream for?

Cetaphil Moisturising Cream can be used long-term as part of a daily skin care routine — there is no recommended maximum duration of use. Because it contains no steroids or active pharmaceutical ingredients, it does not carry the risks associated with prolonged steroid use. Many people with chronic dry skin conditions use it indefinitely as a maintenance moisturiser.

What are the alternatives to Cetaphil Moisturising Cream?

Common alternatives include E45 Cream, Diprobase Cream, Doublebase Gel, and Aveeno Cream — all of which are emollients recommended for dry and sensitive skin. The right choice depends on your skin type, any known allergies, and personal preference for texture. You can browse a range of options in the creams and ointments section at Cured Pharmacy.

What does the latest research say about emollients like Cetaphil Moisturising Cream?

Research continues to support the regular use of emollients as a first-line treatment for dry skin conditions including eczema and psoriasis, with evidence suggesting that consistent use can reduce the frequency and severity of flare-ups. Some studies have also explored whether early emollient use in infants may help reduce the risk of developing eczema, though guidance in this area is still evolving. The NHS and NICE both recommend emollients as a core component of dry skin management.

How Should You Use Cetaphil Moisturising Cream?

Using Cetaphil Moisturising Cream correctly is straightforward, but a few simple steps make a real difference to how well it works. Apply it generously — this is not a product to use sparingly. The NHS recommends that emollients be applied in the direction of hair growth to reduce the risk of blocking hair follicles and causing folliculitis.

What Is the Correct Dose of Cetaphil Moisturising Cream?

There is no fixed dose for an emollient in the same way as a medicine — the key principle is to apply enough to cover the affected area thoroughly. The NHS advises that adults with eczema may use up to 500g of emollient per week for the body, so a 450g tub represents roughly one week's supply for widespread dry skin. Always apply liberally rather than sparingly.

When Is the Best Time to Use Cetaphil Moisturising Cream?

The most effective time to apply Cetaphil Moisturising Cream is immediately after bathing or washing, while the skin is still slightly damp. This helps to lock in moisture before it evaporates from the skin surface. Applying at bedtime is also beneficial, as the skin undergoes repair processes overnight and a generous layer of emollient can support this process without the interference of daily activities.

If you are using the cream alongside a topical corticosteroid, apply the emollient first and wait at least 30 minutes before applying the steroid. This prevents the emollient from diluting the steroid or affecting its absorption.

How Long Can You Use Cetaphil Moisturising Cream For?

Cetaphil Moisturising Cream can be used indefinitely as part of a daily skin care routine. Because it contains no steroids or prescription-only ingredients, there is no maximum duration of use. People with chronic conditions such as eczema or psoriasis often use emollients like this one as a lifelong maintenance treatment. If your skin condition changes significantly or fails to improve with regular use, speak to your GP or pharmacist for further assessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Cetaphil Moisturising Cream?

Cetaphil Moisturising Cream is one of the most well-tolerated emollients available, and the vast majority of people use it without any problems. That said, as with any topical product, mild reactions can occasionally occur — particularly when first starting use or when applying to very dry or broken skin.

  • Mild stinging or tingling immediately after application to cracked or very dry skin
  • Temporary greasiness or heaviness on the skin surface
  • A slight whitish residue if the cream is not fully absorbed before dressing

What Are the Less Common Side Effects of Cetaphil Moisturising Cream?

Less commonly, some people may experience a localised skin reaction. This is more likely in individuals with known sensitivities to any of the ingredients, particularly sweet almond oil in those with nut allergies. If you notice any of the following, stop using the product and seek advice from your pharmacist or GP.

  • Contact dermatitis — redness, itching, or a rash at the site of application
  • Folliculitis — inflammation of hair follicles, which can occur if the cream is applied against the direction of hair growth
  • Increased skin sensitivity or a burning sensation that does not settle within a few minutes
  • Allergic reaction to sweet almond oil or sunflower seed oil

What Are the Serious Side Effects of Cetaphil Moisturising Cream?

Serious side effects are rare with topical emollients. However, a severe allergic reaction (anaphylaxis) is possible in individuals with significant sensitivities to any ingredient. Signs of a serious allergic reaction include swelling of the face, lips, tongue, or throat, difficulty breathing, a widespread rash, or dizziness. If you experience any of these symptoms, stop using the product immediately and call 999 or go to your nearest A&E department.

There is also a fire risk associated with emollient creams. If the cream soaks into fabric — such as clothing, bedding, or dressings — it can make those materials more flammable. Keep away from open flames, cigarettes, and other ignition sources.

What Should You Do If You Experience Side Effects?

For mild reactions such as stinging or temporary redness, simply rinse the area with cool water and allow the skin to settle before deciding whether to continue use. A patch test on a small area of skin before widespread application is always a sensible precaution, especially if you have a history of skin sensitivities. If the reaction is more significant — such as a spreading rash or persistent irritation — stop using the cream and contact your pharmacist or GP for guidance.

Can Cetaphil Moisturising Cream Interact With Other Medicines?

No significant drug interactions are known for Cetaphil Moisturising Cream when used as directed. However, if you are using topical prescription treatments such as corticosteroids, calcineurin inhibitors (e.g. tacrolimus or pimecrolimus), or retinoids, you should apply the emollient separately — ideally at least 30 minutes before or after the prescribed treatment — to avoid affecting absorption. Always inform your GP or pharmacist about all products you are using on your skin, including over-the-counter emollients.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

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Content last updated: 31 Mar 2025

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