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CeraVe Moisturising Cream - 454g

CeraVe Moisturising Cream - 454g

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  • ✔️ Restores skin barrier with three essential ceramides
  • ✔️ Provides up to 24-hour hydration via MVE technology
  • ✔️ Fragrance-free and non-comedogenic — safe for sensitive skin
  • ✔️ Suitable for dry, eczema-prone skin on face and body
  • ✔️ Large 454g tub ideal for whole-body daily use

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What Is CeraVe Moisturising Cream for Dry Skin?

 

If you live with dry, tight, or flaky skin, you'll know how frustrating it can be to find something that actually works day after day. CeraVe moisturising cream is a dermatologist-developed emollient designed to hydrate and help restore the skin's natural protective barrier. The 454g tub is one of the most popular sizes available — generous enough for whole-body use and cost-effective at just £12.49. It's fragrance-free, non-comedogenic, and suitable for use on both the face and body, making it a genuinely versatile option for everyday skincare.

Dry skin is extremely common in the UK. The NHS notes that dry skin can affect people of all ages and is often linked to environmental factors, underlying conditions such as eczema or psoriasis, or simply genetics. Whether your skin feels rough after a shower or you're managing a long-term skin condition, a well-formulated emollient can make a real difference. You can explore a wider range of skin care products at Cured Pharmacy if you're looking for complementary options alongside this cream.

 

How Does CeraVe Moisturising Cream Work?

 

The science behind this cream is straightforward but effective. It uses a patented MVE (MultiVesicular Emulsion) delivery system, which releases moisturising ingredients gradually throughout the day rather than all at once. Think of it like a slow-release capsule — but for your skin.

  • Ceramides (1, 3, and 6-II): These are lipid molecules naturally found in the skin. They make up a significant part of the skin barrier and help prevent moisture loss. CeraVe replenishes all three essential ceramides simultaneously.
  • Hyaluronic acid: A humectant that draws moisture into the skin and helps it retain hydration over time.
  • MVE Technology: Encapsulates the active ingredients in concentric layers, releasing them gradually for up to 24 hours of continuous moisturisation.
  • Glycerin: Another humectant that supports the skin's water-holding capacity and contributes to a smooth texture.

Together, these ingredients work to reinforce the skin barrier, reduce transepidermal water loss (TEWL), and leave skin feeling softer and more comfortable. It's not just a surface fix — it's designed to support the skin's own repair mechanisms over time.

 

Who Should Use CeraVe Moisturising Cream?

 

This cream is suitable for a wide range of people. It's particularly well-suited to those who need a reliable, everyday emollient that won't irritate sensitive or reactive skin. Dermatologists frequently recommend ceramide-based moisturisers for patients with compromised skin barriers, and this product fits that profile well.

  • Adults and children with dry or very dry skin
  • People with eczema-prone or atopic skin
  • Those with sensitive skin who need a fragrance-free, paraben-free option
  • Anyone looking for a non-comedogenic moisturiser safe for facial use
  • Older adults whose skin naturally produces fewer ceramides with age

 

How Does CeraVe Moisturising Cream Compare to E45 Cream?

 

Feature CeraVe Moisturising Cream 454g E45 Cream
Key ingredients Ceramides, hyaluronic acid, glycerin White soft paraffin, light liquid paraffin, lanolin
Fragrance-free Yes Yes
Non-comedogenic Yes Not specified
Skin barrier repair Yes — ceramides actively restore barrier Primarily occlusive — seals in moisture
Suitable for face Yes Yes (body-focused formulation)

 

Is CeraVe Moisturising Cream Suitable for All Ages and How Should It Be Stored?

 

CeraVe moisturising cream is suitable for adults and children, including babies, though it's always worth checking with your GP or pharmacist before using any new product on very young skin. The formula is gentle enough for daily use and has been tested by dermatologists. If you're managing a skin condition in a child, our creams and ointments collection includes a range of options to suit different needs.

Store the cream below 25°C, away from direct sunlight and out of reach of children. Do not use after the expiry date printed on the tub. Once opened, use within 12 months. The large 454g tub is ideal for households where multiple family members use the product regularly.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

CeraVe Moisturising Cream 454g specifications
Treatment category Emollient / Dry skin treatment
Mechanism of action Replenishes ceramides, retains moisture via hyaluronic acid and glycerin, MVE slow-release technology
Effective for Dry, very dry, and eczema-prone skin
Suitable for Adults, children, and babies; sensitive skin; face and body
Active ingredients Ceramides 1, 3, 6-II; Hyaluronic Acid; Glycerin
Pack size 454g
UK classification General Sale (GSL) / Cosmetic
Preparation Cream
Route of administration Topical (skin)

Specifications of CeraVe Moisturising Cream 454g

 

What Is CeraVe Moisturising Cream and What Is It Used For?

 

CeraVe Moisturising Cream is a topical emollient used to relieve and manage dry, very dry, and eczema-prone skin. It works by replenishing the skin's natural ceramide levels, which are essential lipids that help form and maintain the protective skin barrier. When this barrier is compromised — whether through environmental exposure, ageing, or a skin condition — moisture escapes more easily, leaving skin feeling tight, rough, and uncomfortable.

The NHS recommends emollients as a first-line treatment for dry skin conditions including eczema and psoriasis. Regular use of an emollient like this one can reduce the frequency of flare-ups, improve skin texture, and decrease the need for other treatments. It is suitable for daily use on the face and body and can be applied as often as needed throughout the day.

 

What Do You Need to Know Before Using CeraVe Moisturising Cream?

 

This cream is generally very well tolerated, but there are a few things to be aware of before you start using it.

Do not use this product if:

  • You are allergic to any of the ingredients, including ceramides, hyaluronic acid, or any excipients listed on the label
  • You have an active skin infection — treat the infection first before applying emollients
  • You have been advised by a healthcare professional to avoid occlusive or emollient products on a specific area

Warnings and precautions:

  • Avoid contact with the eyes — if contact occurs, rinse thoroughly with water
  • Do not apply to broken, bleeding, or severely inflamed skin without medical advice
  • Emollients can make surfaces slippery — take care in the bath or shower after application
  • Fabric soaked with emollient products can be a fire hazard — keep away from open flames
  • If your skin condition worsens or does not improve after regular use, consult your GP or pharmacist

Known drug interactions:

  • No clinically significant drug interactions are known for topical emollients of this type
  • If you are using topical corticosteroids or other prescribed skin treatments, apply them separately and allow each product to absorb before applying the next

 

How Should You Use CeraVe Moisturising Cream?

 

Using this cream correctly will help you get the most out of it. Consistency matters — applying it regularly, even when your skin feels better, helps maintain the barrier and prevent dryness returning.

  1. Wash and gently pat your skin dry before application
  2. Scoop out a generous amount using clean fingers or a spatula
  3. Apply to the affected area using gentle, circular or downward strokes
  4. Allow the cream to absorb before dressing or applying other products
  5. Repeat as needed — at least twice daily is recommended for dry skin conditions
Indication Age Group Amount Frequency
Dry / very dry skin Adults Generous layer to affected area 2–3 times daily or as needed
Eczema-prone skin Adults and children Generous layer to affected area At least twice daily
General daily moisturisation All ages Small to moderate amount Once or twice daily

If you are also using prescribed topical treatments, apply CeraVe separately and allow adequate time between applications. For broader skin health support, you might also want to browse our skin care range for complementary products.

 

What Are the Possible Side Effects of CeraVe Moisturising Cream?

 

Side effects from this cream are uncommon. Because it is fragrance-free and dermatologist-tested, it is less likely to cause reactions than many other moisturisers. That said, any topical product can occasionally cause a reaction in sensitive individuals.

Common side effects (may affect a small number of users):

  • Mild stinging or tingling on first application, particularly on very dry or broken skin
  • Temporary redness at the application site
  • A feeling of greasiness immediately after application

Less common side effects:

  • Allergic contact dermatitis — rash, itching, or swelling at the site of application
  • Acneiform eruptions in individuals with acne-prone skin (though the formula is non-comedogenic)

If you experience any signs of a serious allergic reaction — including swelling of the face, lips, or throat, or difficulty breathing — stop using the product immediately and seek urgent medical attention.

 

How Should You Store CeraVe Moisturising Cream?

 

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the lid tightly closed when not in use
  • Keep out of reach and sight of children
  • Do not use after the expiry date printed on the tub
  • Once opened, use within 12 months
  • Do not store in the bathroom if it is frequently humid — a bedroom or bedroom shelf is preferable

Proper storage helps maintain the integrity of the ceramides and hyaluronic acid in the formula. If the cream changes colour, smell, or texture, do not use it. You can find further guidance on managing dry skin conditions on the NHS website. If you're also managing a related condition, our creams and ointments collection has a range of emollients and topical treatments to consider.

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Frequently Asked Questions

Where can I buy CeraVe Moisturising Cream 454g online in the UK?

You can buy CeraVe Moisturising Cream 454g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £12.49. No prescription is required and it can be ordered for home delivery. It's also available in some high street pharmacies and supermarkets across the UK.

How does CeraVe Moisturising Cream work on dry skin?

The cream works by replenishing three essential ceramides — naturally occurring lipids that form part of the skin's protective barrier. When ceramide levels are low, the skin loses moisture more easily, leading to dryness and irritation. CeraVe's MVE technology releases these ingredients gradually over 24 hours to maintain continuous hydration.

How do I use CeraVe Moisturising Cream step by step?

Start by washing and gently patting your skin dry. Scoop out a generous amount using clean fingers or a spatula, then apply to the affected area using gentle circular motions. Allow it to absorb fully before dressing or applying other skincare products, and repeat at least twice daily for best results.

Can I use CeraVe Moisturising Cream on my face?

Yes — the formula is non-comedogenic, meaning it won't block pores, and is suitable for facial use. It's particularly helpful for people with dry or sensitive facial skin. Just avoid direct contact with the eyes, and if any product gets into your eyes, rinse thoroughly with water.

Is CeraVe Moisturising Cream suitable for eczema-prone skin?

Yes, it is widely used by people with eczema-prone skin and is often recommended by dermatologists as part of an eczema management routine. The NHS recommends regular emollient use to help maintain the skin barrier and reduce flare-up frequency. It is fragrance-free and paraben-free, which reduces the risk of triggering a reaction.

What are the side effects of CeraVe Moisturising Cream?

Side effects are uncommon but can include mild stinging, temporary redness, or a feeling of greasiness on first application. Rarely, some people may experience allergic contact dermatitis — if you notice a rash, itching, or swelling, stop using the product and speak to your pharmacist. Serious allergic reactions are very rare but require immediate medical attention.

Is CeraVe Moisturising Cream safe to use during pregnancy?

CeraVe Moisturising Cream contains no ingredients known to be harmful during pregnancy, and it is generally considered safe for topical use. However, it's always sensible to check with your GP or midwife before introducing any new skincare product during pregnancy. The fragrance-free formula makes it a particularly gentle option for those with heightened skin sensitivity during pregnancy.

Can I use CeraVe Moisturising Cream on a baby or young child?

The cream is formulated to be gentle enough for use on babies and young children, and it is free from fragrance and parabens. That said, always consult your GP or health visitor before applying any new product to a baby's skin, especially if they have a known skin condition. Our baby and toddler range also includes other gentle skincare options.

How does CeraVe Moisturising Cream compare to E45 cream?

Both are emollients for dry skin, but they work differently. CeraVe contains ceramides and hyaluronic acid to actively restore the skin barrier, while E45 relies primarily on white soft paraffin and lanolin as occlusive agents that seal in moisture. CeraVe is also non-comedogenic and suitable for facial use, which E45 is less commonly recommended for.

How often should I apply CeraVe Moisturising Cream?

For dry or very dry skin, applying the cream at least twice daily — morning and evening — is generally recommended. You can apply it more frequently if needed, particularly after washing your hands or bathing. Consistency is key: regular use helps maintain the skin barrier even when your skin feels comfortable.

What is the best time to apply CeraVe Moisturising Cream?

The most effective time to apply any emollient is immediately after bathing or washing, while the skin is still slightly damp — this helps lock in moisture. Applying again before bed gives the cream time to work overnight when the skin naturally repairs itself. A morning application helps protect the skin barrier throughout the day.

How long can I use CeraVe Moisturising Cream for?

CeraVe Moisturising Cream is safe for long-term, continuous daily use — there is no recommended maximum duration. Emollients are designed to be used as part of an ongoing skincare routine rather than as a short-term treatment. If your skin condition does not improve or worsens over time, speak to your GP or pharmacist for further assessment.

Does CeraVe Moisturising Cream contain steroids?

No — CeraVe Moisturising Cream does not contain any corticosteroids. It is a plain emollient and moisturiser, not a medicated treatment. If you need a steroid cream for a skin condition such as eczema, this would be prescribed separately by your GP and used alongside an emollient like CeraVe.

What are the alternatives to CeraVe Moisturising Cream for dry skin?

There are several emollients available for dry skin in the UK, including E45 Cream, Doublebase Gel, Diprobase Cream, and Aveeno Moisturising Cream. The right choice depends on your skin type, any underlying conditions, and personal preference. You can browse a range of options in our creams and ointments collection to find what suits you best.

What are the latest findings on ceramide moisturisers for skin barrier repair?

Research continues to support the role of ceramide-containing emollients in restoring the skin barrier, particularly in conditions like atopic dermatitis. Studies published in dermatology literature suggest that topical ceramide formulations can reduce transepidermal water loss and improve skin hydration scores. The NHS and dermatology guidelines consistently recommend emollient therapy as a cornerstone of dry skin and eczema management.

How Should You Use CeraVe Moisturising Cream?

Using CeraVe Moisturising Cream correctly makes a real difference to how well it works. Apply it consistently as part of your daily skincare routine, and don't wait until your skin feels very dry before reaching for it — regular use is what maintains the barrier over time.

For very dry or eczema-prone skin, apply liberally and frequently. There is no upper limit on how much you can use — the more consistently you apply it, the better the results tend to be.

What Is the Correct Dose of CeraVe Moisturising Cream?

There is no fixed dose for emollients — the amount you use depends on the size of the area being treated and how dry your skin is. As a general guide, use enough to cover the affected area with a visible layer of cream, then allow it to absorb. The NHS advises that emollients should be applied generously and frequently for best results.

When Is the Best Time to Use CeraVe Moisturising Cream?

The most effective time to apply this cream is immediately after bathing or washing, while the skin is still slightly damp. This helps to lock in moisture before it evaporates from the skin surface. Applying it again before bed is also beneficial, as the skin undergoes natural repair processes overnight and the cream can work undisturbed.

A morning application helps protect the skin barrier throughout the day, particularly if you work in a dry or air-conditioned environment. If your hands are frequently washed — for example, in a healthcare or catering role — reapplying after each wash is a sensible habit.

How Long Can You Use CeraVe Moisturising Cream For?

CeraVe Moisturising Cream is designed for long-term, continuous daily use. Unlike medicated treatments, there is no recommended maximum duration — it can be used indefinitely as part of your regular skincare routine. In fact, stopping use when your skin feels better is a common mistake; maintaining the barrier requires ongoing application.

If you are using it to manage a diagnosed skin condition such as eczema or psoriasis, your GP or dermatologist may advise on how it fits into your broader treatment plan. If your skin does not improve after several weeks of regular use, or if it worsens, seek advice from your pharmacist or GP.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of CeraVe Moisturising Cream?

CeraVe Moisturising Cream is well tolerated by most people, including those with sensitive skin. Because it is fragrance-free, paraben-free, and dermatologist-tested, the risk of a reaction is lower than with many other moisturisers. That said, any topical product can occasionally cause a mild response, particularly when first used on very dry or compromised skin.

  • Mild stinging or tingling on first application to very dry or broken skin
  • Temporary redness at the application site
  • A feeling of greasiness or heaviness immediately after application
  • Slight whitish residue if applied too thickly and not fully absorbed

What Are the Less Common Side Effects of CeraVe Moisturising Cream?

Less common reactions are rare but can occur in individuals with particular sensitivities to any of the ingredients. If you have a history of contact allergies or very reactive skin, it is worth doing a small patch test on the inner arm before applying to a larger area.

  • Allergic contact dermatitis — presenting as a rash, itching, or localised swelling
  • Acneiform eruptions in individuals with acne-prone skin, despite the non-comedogenic formulation
  • Folliculitis (inflammation of hair follicles) if the cream is applied against the direction of hair growth on the body

What Are the Serious Side Effects of CeraVe Moisturising Cream?

Serious side effects are very rare with topical emollients. However, a small number of people may experience a systemic allergic reaction. This is not expected with a product of this type, but you should be aware of the signs.

Seek immediate medical attention if you experience any of the following after applying the cream: swelling of the face, lips, tongue, or throat; difficulty breathing or swallowing; a widespread skin rash or hives; or dizziness and feeling faint. These may indicate anaphylaxis, which requires emergency treatment.

What Should You Do If You Experience Side Effects of CeraVe Moisturising Cream?

If you notice mild irritation such as redness or stinging, stop using the cream on that area and allow the skin to settle. You can try reintroducing it after a few days, or switch to a different emollient if the reaction persists. For any signs of an allergic reaction — rash, itching, or swelling — discontinue use immediately and speak to your pharmacist or GP.

Do not ignore a worsening skin reaction. If your skin condition deteriorates while using this product, it is important to seek professional advice rather than continuing to apply it. Your pharmacist can help identify whether the reaction is related to the cream or to an underlying skin condition.

Can CeraVe Moisturising Cream Interact With Other Medicines?

No clinically significant drug interactions are known for CeraVe Moisturising Cream. It is a topical emollient with no systemic absorption under normal use conditions. If you are using prescribed topical treatments — such as corticosteroid creams, calcineurin inhibitors, or antibiotic ointments — apply them separately and allow each product to absorb before applying the next. This prevents dilution of the active treatment and ensures both products work as intended. Always follow the advice of your GP or dermatologist regarding the order and timing of topical applications.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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