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Acnecide Face 5% w/w Gel

Acnecide Face 5% w/w Gel

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  • ✔️ Targets acne-causing bacteria with 5% benzoyl peroxide
  • ✔️ Reduces inflammation, spots, and blocked pores effectively
  • ✔️ Visible improvement in acne typically within 4–6 weeks
  • ✔️ Suitable for adults and teenagers aged 12 and over
  • ✔️ Antibiotic-free formula — no risk of bacterial resistance

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Is Acnecide Face 5% w/w Gel the Right Benzoyl Peroxide Gel for Acne?

 

Acne is one of the most common skin conditions in the UK, affecting up to 95% of people aged 11 to 30 at some point in their lives, according to the NHS. It can knock your confidence, cause discomfort, and — if left untreated — lead to scarring. Acnecide Face 5% w/w Gel is a clinically established, over-the-counter treatment that targets the root causes of acne rather than just masking the symptoms. Available from Cured Pharmacy for just £7.99, it offers an accessible route to clearer skin without needing a prescription. You can explore our wider range of skin care products if you're looking for complementary treatments.

The active ingredient is benzoyl peroxide at a concentration of 5% w/w. This is a well-established topical antibacterial agent with decades of clinical use behind it. It's recommended by dermatologists and referenced in NHS guidance as a first-line option for mild to moderate acne vulgaris.

 

How Does Acnecide Face 5% w/w Gel Work on Acne?

 

Benzoyl peroxide works through a straightforward but effective mechanism. When applied to the skin, it breaks down into benzoic acid and oxygen. That release of oxygen creates an environment that is hostile to Cutibacterium acnes (formerly known as Propionibacterium acnes), the anaerobic bacterium largely responsible for inflamed acne lesions.

  • Releases oxygen into the skin to kill acne-causing bacteria
  • Reduces excess sebum production in the pores
  • Has a mild keratolytic (skin-shedding) effect that helps unblock follicles
  • Does not carry the same risk of antibiotic resistance as topical antibiotics

Because it doesn't rely on antibiotics, there's no concern about bacterial resistance developing over time — a real advantage compared to some other acne treatments.

 

Who Should Consider Using Acnecide Face 5% w/w Gel?

 

This gel is suitable for adults and adolescents aged 12 and over who are dealing with mild to moderate acne, particularly on the face. It's especially useful if you have inflammatory spots (papules and pustules) rather than purely non-inflammatory blackheads. That said, it can help with both types.

  • Teenagers and adults with facial acne vulgaris
  • People who want an antibiotic-free acne treatment
  • Those who have not responded well to gentle cleansers alone
  • Individuals looking for an OTC option before seeking a GP referral

It is not recommended for children under 12, and you should avoid it if you have known hypersensitivity to benzoyl peroxide or any of the excipients listed in the product leaflet.

 

How Does Acnecide Compare to Other Acne Gel Treatments?

 

Feature Acnecide Face 5% w/w Gel Salicylic Acid Gel (e.g. 2%)
Active ingredient Benzoyl peroxide 5% Salicylic acid 2%
Primary action Antibacterial + keratolytic Keratolytic (unblocks pores)
Best for Inflammatory acne (papules, pustules) Blackheads and comedonal acne
Antibiotic resistance risk None None

 

Is Acnecide Face 5% w/w Gel Suitable for Long-Term Use and How Should It Be Stored?

 

Benzoyl peroxide gel for acne like Acnecide can be used as part of an ongoing skincare routine, but it's worth reviewing your treatment with a pharmacist or GP if you haven't seen improvement after 8 to 12 weeks. Long-term use is generally considered safe, though some people find they need to adjust frequency to manage dryness. If you're also managing other skin concerns, our range of creams and ointments may offer useful complementary options.

Store Acnecide Face 5% w/w Gel below 25°C, away from direct heat and sunlight. Keep the tube tightly closed when not in use, and always store it out of the reach and sight of children. Do not use after the expiry date printed on the packaging.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Acnecide Face 5% w/w Gel specifications
Treatment category Acne treatment
Mechanism of action Antibacterial and keratolytic via benzoyl peroxide
Effective for Mild to moderate acne vulgaris
Suitable for Adults and adolescents aged 12 and over
Active ingredient Benzoyl peroxide 5% w/w
Pack size 30 g tube
Strength 5% w/w
UK classification General Sale / Pharmacy (P) medicine
Drug class Topical antibacterial / keratolytic
Preparation Gel
Route of administration Topical (cutaneous)

Specifications of Acnecide Face 5% w/w Gel

 

What Is Acnecide Face 5% w/w Gel and What Is It Used For?

 

Acnecide Face 5% w/w Gel is a topical medicine containing benzoyl peroxide as its active ingredient. It is used to treat mild to moderate acne vulgaris — the type of acne characterised by blackheads, whiteheads, papules, and pustules, most commonly appearing on the face. The NHS recognises benzoyl peroxide as one of the first-line treatments for acne, and it has been used safely and effectively for many years. This gel is available over the counter, meaning you don't need a prescription to purchase it.

 

What Do You Need to Know Before Using Acnecide Face 5% w/w Gel?

 

Before you start using this gel, there are some important things to be aware of. Read the following carefully.

Do not use Acnecide if you:

  • Are allergic to benzoyl peroxide or any other ingredient in the gel
  • Are under 12 years of age
  • Have eczema, seborrhoeic dermatitis, or very sensitive skin (use with caution and seek advice first)
  • Are pregnant or breastfeeding — speak to your GP or pharmacist before use

Warnings and precautions:

  • Avoid contact with eyes, nostrils, mouth, and other mucous membranes
  • Benzoyl peroxide can bleach hair, clothing, towels, and bedding — take care during application
  • Avoid excessive sun exposure while using this product; use a non-comedogenic SPF if going outdoors
  • Do not apply to broken, sunburned, or windburned skin
  • If severe irritation occurs, stop use and consult a pharmacist or GP

Drug interactions to be aware of:

  • Avoid using alongside other topical acne treatments (e.g. retinoids, topical antibiotics) unless directed by a healthcare professional
  • Do not use with other drying or exfoliating products at the same time, as this may worsen irritation
  • No significant systemic drug interactions are known for topical benzoyl peroxide at this concentration

 

How Should You Use Acnecide Face 5% w/w Gel Correctly?

 

Using this gel correctly gives you the best chance of seeing results. Follow these steps carefully:

  1. Wash the affected area gently with a mild, non-comedogenic cleanser and pat dry
  2. Squeeze a small, pea-sized amount of gel onto a clean fingertip
  3. Apply a thin, even layer to the entire affected area — not just individual spots
  4. Wash your hands thoroughly after application
  5. Allow the gel to absorb fully before applying any moisturiser or other skincare products
  6. Use once daily, preferably in the evening, to begin with — you can increase to twice daily if tolerated
Indication Age Group Dose Frequency
Mild to moderate acne vulgaris 12 years and over Thin layer to affected area Once daily (increasing to twice daily if tolerated)
Not recommended Under 12 years

If you're also exploring other skin health options, our skin care collection includes a range of products to support your routine.

 

What Are the Possible Side Effects of Acnecide Face 5% w/w Gel?

 

Like all medicines, Acnecide can cause side effects, although not everyone experiences them. Many side effects are mild and tend to improve as your skin adjusts during the first few weeks of treatment.

Common side effects (may affect more than 1 in 10 people):

  • Skin dryness
  • Redness and irritation at the application site
  • Peeling or flaking skin
  • Mild stinging or burning sensation on first application

Less common side effects (may affect fewer than 1 in 10 people):

  • Contact dermatitis (allergic skin reaction)
  • Oedema (swelling) at the application site
  • Blistering or crusting of the skin

If you experience signs of a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a severe rash — stop using the gel immediately and seek urgent medical attention. You can also find supportive skincare options in our creams and ointments range to help manage dryness alongside your acne treatment.

 

How Should You Store Acnecide Face 5% w/w Gel Safely?

 

  • Store below 25°C in a cool, dry place
  • Do not refrigerate or freeze
  • Keep the tube tightly closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tube and carton
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Acnecide Face 5% w/w Gel online in the UK?

You can buy Acnecide Face 5% w/w Gel directly from Cured Pharmacy, a GPhC-registered online pharmacy, for just £7.99. No prescription is needed, as it is available as an over-the-counter medicine. Simply add it to your basket and it will be dispatched to your door.

How does Acnecide Face 5% w/w Gel work in the skin?

Acnecide contains benzoyl peroxide, which releases oxygen into the skin when applied. This oxygen kills the anaerobic bacteria Cutibacterium acnes that contributes to inflamed spots. It also has a mild keratolytic effect, helping to shed dead skin cells and unblock pores.

How do I apply Acnecide Face 5% w/w Gel step by step?

Start by washing and drying the affected area with a gentle cleanser. Apply a thin layer of the gel to the whole affected area — not just individual spots — once daily to begin with. Wash your hands after application and allow the gel to absorb before applying any other products.

How long does Acnecide take to show results?

Most people notice an improvement in their acne after around 4 to 6 weeks of consistent daily use. Full results typically take up to 3 months. If you see no improvement after 8 to 12 weeks, speak to your pharmacist or GP about alternative options.

What are the most common side effects of Acnecide Face 5% w/w Gel?

The most common side effects are skin dryness, redness, peeling, and mild stinging — particularly during the first few weeks of use. These usually settle as your skin adjusts. Using a non-comedogenic moisturiser can help manage dryness without blocking pores.

How do I manage dryness and irritation caused by Acnecide?

If you experience dryness or irritation, try reducing application to every other day until your skin adapts. Applying a gentle, non-comedogenic moisturiser after the gel has fully absorbed can also help. If irritation is severe or persistent, stop use and consult your pharmacist.

Is Acnecide Face 5% w/w Gel suitable for teenagers?

Yes, Acnecide is suitable for adolescents aged 12 and over. It is one of the most commonly recommended OTC acne treatments for teenagers dealing with mild to moderate facial acne. It should not be used in children under 12 years of age.

Can I use Acnecide if I have sensitive skin?

Acnecide can be used on sensitive skin, but you should start with once-daily application and monitor your skin's response carefully. Benzoyl peroxide can cause more pronounced dryness and irritation on sensitive skin types. If you find it too harsh, speak to your pharmacist about whether a lower-strength product might be more appropriate.

Can I use Acnecide alongside other acne treatments?

You should avoid combining Acnecide with other topical acne treatments — such as retinoids or topical antibiotics — unless a doctor or pharmacist has specifically advised you to do so. Using multiple active treatments at once can significantly increase the risk of skin irritation. Always check with a healthcare professional before combining treatments.

Will Acnecide bleach my clothes or towels?

Yes — benzoyl peroxide is an oxidising agent and can bleach hair, clothing, towels, and bedding if it comes into contact with them. Allow the gel to absorb fully before touching fabrics, and consider using old or white towels and pillowcases while using this product.

What happens if I miss a dose of Acnecide?

If you forget to apply Acnecide one day, simply continue with your normal routine the following day. Do not apply a double amount to make up for a missed application. Consistency over time is what delivers results, so try to build it into your daily skincare routine.

How long can I use Acnecide Face 5% w/w Gel for?

Acnecide can be used as part of an ongoing acne management routine, but it is advisable to review your treatment with a pharmacist or GP every 8 to 12 weeks. If your acne has not improved or has worsened, a different treatment approach may be needed. Long-term use is generally considered safe when used as directed.

What are the alternatives to Acnecide Face 5% w/w Gel?

Alternatives include other topical benzoyl peroxide products at different concentrations, salicylic acid-based treatments for comedonal acne, or prescription options such as topical retinoids or antibiotic gels. You can browse our skin care range for other options, or speak to your GP if OTC treatments haven't worked.

Is Acnecide safe to use during pregnancy or breastfeeding?

The safety of benzoyl peroxide during pregnancy and breastfeeding has not been fully established. You should speak to your GP or pharmacist before using Acnecide if you are pregnant, planning to become pregnant, or breastfeeding. They can advise on the most appropriate acne management for your situation.

What are the latest clinical findings on benzoyl peroxide for acne?

Benzoyl peroxide remains one of the most well-evidenced topical treatments for acne vulgaris and is consistently recommended in UK clinical guidelines. A key advantage highlighted in current literature is that, unlike topical antibiotics, it does not contribute to antibiotic resistance — making it a preferred long-term option. You can also explore our creams and ointments collection for further skin treatment options.

How Should You Use Acnecide Face 5% w/w Gel?

Using Acnecide correctly is key to getting the best results. Always read the patient information leaflet before starting treatment, and follow these steps each time you apply the gel.

If you experience significant dryness or irritation in the first week or two, try applying the gel every other day until your skin adjusts. This is a normal part of the process for many people.

What Is the Correct Dose of Acnecide Face 5% w/w Gel?

The correct dose is a thin layer applied to the affected area. You should not apply more than directed — using a larger amount does not improve results and is more likely to cause irritation.

When Is the Best Time to Use Acnecide Face 5% w/w Gel?

Applying Acnecide in the evening is generally recommended, particularly when you first start treatment. This is because benzoyl peroxide can increase your skin's sensitivity to sunlight, so applying it at night reduces the risk of sun-related irritation. If you do apply it during the day, use a non-comedogenic SPF moisturiser to protect your skin.

Once your skin has adjusted and you're tolerating the gel well, you may increase to twice-daily application — once in the morning and once in the evening — if your pharmacist or GP advises this.

How Long Can You Use Acnecide Face 5% w/w Gel For?

Acnecide can be used as part of a longer-term acne management routine. Most people begin to see visible improvement after 4 to 6 weeks, with more significant results after 3 months of consistent use. It is advisable to review your treatment with a pharmacist or GP every 8 to 12 weeks to assess progress.

If your acne has not improved after 12 weeks of regular use, or if it worsens at any point, stop using the gel and seek advice from your GP. They may recommend a prescription treatment or refer you to a dermatologist.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Acnecide Face 5% w/w Gel?

Most people who use Acnecide experience some degree of skin adjustment during the first few weeks of treatment. These effects are usually mild and tend to improve as your skin gets used to the benzoyl peroxide.

  • Skin dryness and tightness at the application site
  • Redness or flushing of the treated area
  • Peeling or flaking skin
  • Mild stinging or burning sensation on first application

These reactions are generally a sign that the gel is working. Reducing application frequency to every other day and using a gentle, non-comedogenic moisturiser can help manage these effects while your skin adapts.

What Are the Less Common Side Effects of Acnecide Face 5% w/w Gel?

Some people may experience less common reactions that are more significant. If any of the following occur, reduce use and speak to your pharmacist.

  • Contact dermatitis — an allergic skin reaction causing intense redness, itching, or a rash
  • Swelling or oedema at the application site
  • Blistering or crusting of the skin
  • Excessive skin sensitivity to sunlight (photosensitivity)

What Are the Serious Side Effects of Acnecide Face 5% w/w Gel?

Serious side effects are rare but require immediate attention. Stop using Acnecide and seek urgent medical help if you notice any signs of a severe allergic reaction (anaphylaxis), including swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, or a sudden widespread rash. These reactions, while uncommon, can be serious and should never be ignored.

What Should You Do If You Experience Side Effects from Acnecide?

For mild side effects such as dryness or peeling, try applying the gel less frequently — every other day rather than daily — and introduce a non-comedogenic moisturiser into your routine. If irritation is moderate, take a short break from the gel for a few days before restarting at a lower frequency. For any severe or unexpected reaction, stop use immediately and contact your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Acnecide Face 5% w/w Gel Interact With Other Medicines?

Topical benzoyl peroxide at 5% concentration has no known significant systemic drug interactions. However, you should avoid using Acnecide at the same time as other topical acne treatments — particularly retinoids, topical antibiotics, or other exfoliating agents — as combining these can significantly increase skin irritation and dryness. Always inform your pharmacist of any other medicines or skincare products you are using before starting Acnecide.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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