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Acnecide 5% w/w Gel

Acnecide 5% w/w Gel

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  • ✔️ Targets acne-causing bacteria with 5% benzoyl peroxide
  • ✔️ Reduces blackheads, whiteheads, and inflamed spots
  • ✔️ Visible improvement in acne typically within 4–6 weeks
  • ✔️ Antibiotic-free formula — no risk of bacterial resistance
  • ✔️ Suitable for facial, back, and chest acne from age 12

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What Is Acnecide 5 Gel and How Does It Treat Acne?

 

Acne is one of the most common skin conditions in the UK, affecting up to 95% of people aged 11 to 30 at some point in their lives, according to the NHS. It can affect your confidence, your daily routine, and your overall wellbeing — so finding something that actually works matters. Acnecide 5 gel is a clinically established, pharmacy-strength topical treatment containing 5% w/w benzoyl peroxide, designed to tackle mild to moderate acne vulgaris on the face, back, and chest. You can browse the full range of topical treatments in our skin care collection at Cured Pharmacy.

This gel is available over the counter without a prescription, making it accessible for adults and young people who want to address breakouts without waiting for a GP appointment. It is manufactured by Galderma, a well-recognised dermatology brand, and is licensed for use in the UK.

 

How Does Acnecide 5% w/w Gel Work on Skin?

 

Benzoyl peroxide, the active ingredient in this gel, works through a well-understood mechanism that targets the root causes of acne rather than just masking symptoms. Here is how it works:

  • Antibacterial action: Benzoyl peroxide releases free-radical oxygen into the follicle, which kills Cutibacterium acnes (formerly known as Propionibacterium acnes), the bacteria responsible for inflamed spots.
  • Keratolytic effect: It helps to loosen and shed dead skin cells that can block pores, reducing the formation of comedones (blackheads and whiteheads).
  • Sebum reduction: Regular use can help reduce excess oil production in the skin, which is a key driver of acne development.
  • No antibiotic resistance: Unlike topical antibiotics, benzoyl peroxide does not contribute to bacterial resistance — an important clinical advantage.

 

Who Is Acnecide 5% w/w Gel Suitable For?

 

This gel is suitable for a broad range of people dealing with acne, but it is not appropriate for everyone. It is generally recommended for:

  • Adults and adolescents aged 12 and over with mild to moderate acne vulgaris
  • People with acne on the face, chest, or back
  • Those who have not responded adequately to gentle cleansing alone
  • Individuals looking for an antibiotic-free acne treatment option

It is not recommended for children under 12, and you should speak to a pharmacist or GP before using it if you have sensitive or eczema-prone skin. If you are also managing other skin concerns, our creams and ointments collection includes a range of complementary topical products.

 

How Does Acnecide 5% Gel Compare to Other Acne Treatments?

 

Feature Acnecide 5% w/w Gel Topical Antibiotic (e.g. Dalacin T)
Active ingredient Benzoyl peroxide 5% Clindamycin 1%
Antibiotic resistance risk None Yes — possible with prolonged use
Prescription required No (OTC) Yes (prescription only)
Suitable for long-term use Up to 3 months OTC; longer under supervision Usually limited to 12 weeks

 

How Should You Store Acnecide 5% w/w Gel?

 

Store acnecide 5 gel below 25°C, away from direct heat and sunlight. Keep the tube tightly closed when not in use, and always store it out of the reach and sight of children. Do not use the gel after the expiry date printed on the packaging — using an expired product may reduce its effectiveness or cause unexpected skin reactions.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Acnecide 5% w/w Gel specifications
Treatment category Acne treatment
Mechanism of action Antibacterial and keratolytic via benzoyl peroxide
Effective for Mild to moderate acne vulgaris
Suitable for Adults and adolescents aged 12 and over
Active ingredient Benzoyl peroxide 5% w/w
Pack size 30g tube
Strength 5% w/w
UK classification General Sale / Pharmacy (P)
Drug class Topical antibacterial / keratolytic
Preparation Gel
Route of administration Topical (cutaneous)

Specifications of Acnecide 5% w/w Gel

 

What Is Acnecide 5% w/w Gel and What Is It Used For?

 

Acnecide 5% w/w Gel is a topical medicine used to treat mild to moderate acne vulgaris. It contains benzoyl peroxide 5% w/w as its active ingredient. Acne vulgaris is a common skin condition that occurs when hair follicles become blocked with sebum and dead skin cells, leading to spots, blackheads, whiteheads, and sometimes deeper cysts. The NHS notes that acne most commonly affects the face, back, and chest, and is particularly prevalent during adolescence, though it can affect adults of any age.

Acnecide 5 gel is applied directly to the affected skin and works locally to reduce the bacteria and blockages that cause breakouts. It is available without a prescription for people aged 12 and over.

 

What Do You Need to Know Before Using Acnecide 5% w/w Gel?

 

Before you start using this gel, there are some important contraindications and precautions to be aware of:

  • Do not use if you are allergic to benzoyl peroxide or any other ingredient in the formulation
  • Do not apply to broken, sunburned, or severely irritated skin
  • Avoid contact with eyes, mouth, nostrils, and other mucous membranes
  • Do not use on children under 12 years of age
  • Consult your doctor or pharmacist before use if you are pregnant or breastfeeding
  • Benzoyl peroxide may bleach hair, clothing, and bed linen — take care during application
  • Avoid excessive sun exposure while using this product; use a non-comedogenic sunscreen if going outdoors

Regarding drug interactions, there are limited systemic interactions due to the topical nature of this medicine. However, be aware of the following:

  • Avoid using simultaneously with other topical acne treatments (e.g. retinoids, salicylic acid) unless directed by a healthcare professional, as this may increase skin irritation
  • Do not use alongside topical antibiotic preparations without medical advice
  • Avoid using with abrasive or alcohol-based skin products at the same time

 

How Should You Use Acnecide 5% w/w Gel Correctly?

 

Follow these steps carefully to get the most from your treatment and minimise the risk of irritation:

  1. Wash the affected area gently with a mild, non-medicated cleanser and pat dry
  2. Squeeze a small, pea-sized amount of gel onto a clean fingertip
  3. Apply a thin, even layer to the entire affected area — not just individual spots
  4. Wash your hands thoroughly after application
  5. Allow the gel to dry before applying any moisturiser or make-up
  6. Use once daily, preferably in the evening, for the first week to allow your skin to adjust
  7. After one week, you may increase to twice daily if tolerated and if your skin is not excessively dry or irritated
Indication Age Group Dose Frequency
Mild to moderate acne vulgaris 12 years and over Thin layer to affected area Once daily (increasing to twice daily if tolerated)
Mild to moderate acne vulgaris Under 12 years Not recommended — seek medical advice

If you are exploring other skin care options alongside your acne treatment, you may find our wider skin care collection helpful for complementary products such as gentle cleansers and moisturisers.

 

What Are the Possible Side Effects of Acnecide 5% w/w Gel?

 

Like all medicines, Acnecide 5% w/w Gel can cause side effects, although not everyone experiences them. Most side effects are localised to the skin and tend to be mild, particularly during the first few weeks of use as your skin adjusts.

Common side effects (may affect more than 1 in 10 people):

  • Skin dryness and peeling at the application site
  • Redness (erythema) of the treated skin
  • Mild burning or stinging sensation after application
  • Skin irritation or tightness

Less common side effects (may affect fewer than 1 in 10 people):

  • Contact dermatitis (allergic skin reaction)
  • Oedema (swelling) at the application site
  • Blistering or severe skin peeling — stop use and seek medical advice if this occurs

If you experience signs of a serious allergic reaction — such as swelling of the face, lips, or throat, difficulty breathing, or a widespread rash — stop using the gel immediately and seek urgent medical attention.

 

How Should You Store Acnecide 5% w/w Gel Safely?

 

Correct storage helps maintain the gel's effectiveness and keeps it safe for use throughout its shelf life. You can also find guidance on storing other topical medicines in our creams and ointments collection pages.

  • Store below 25°C in a cool, dry place
  • Do not refrigerate or freeze
  • Keep the tube tightly closed after each use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tube and carton
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Acnecide 5% w/w Gel online in the UK?

You can buy Acnecide 5% w/w Gel online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £15.70. It is available without a prescription and can be ordered directly through our skin care collection. It is also stocked in some high street pharmacies across the UK.

How does Acnecide 5% w/w Gel work in the body?

Acnecide 5% w/w Gel works topically — it is not absorbed into the bloodstream in significant amounts. The benzoyl peroxide releases oxygen into the skin follicle, killing acne-causing bacteria, loosening blocked pores, and reducing excess sebum production. Because it acts locally on the skin, systemic side effects are very rare.

How do I use Acnecide 5% w/w Gel step by step?

Cleanse the affected area with a gentle, non-medicated wash and pat dry before applying a thin layer of the gel to the whole affected area — not just individual spots. Apply once daily in the evening for the first week, then increase to twice daily if your skin tolerates it well. Always wash your hands after application and avoid contact with eyes and mouth.

How long does Acnecide 5% w/w Gel take to work?

Most people notice an improvement in their acne within 4 to 6 weeks of consistent daily use. Full results, including a significant reduction in spots and inflammation, typically take up to 3 months. If you see no improvement after 3 months, speak to your GP or pharmacist for further assessment.

What are the side effects of Acnecide 5% w/w Gel and how do I manage them?

The most common side effects are skin dryness, redness, and mild irritation, which often settle after the first few weeks as your skin adjusts. To manage these, start with once-daily application and use a non-comedogenic, fragrance-free moisturiser after the gel has dried. If irritation is severe or persistent, reduce frequency of use and consult your pharmacist.

Who is eligible to use Acnecide 5% w/w Gel?

Acnecide 5% w/w Gel is suitable for adults and adolescents aged 12 and over with mild to moderate acne vulgaris. It is not recommended for children under 12, and those who are pregnant, breastfeeding, or have sensitive or eczema-prone skin should consult a healthcare professional before use. People with a known allergy to benzoyl peroxide should not use this product.

What happens if I miss a dose of Acnecide 5% w/w Gel?

If you forget to apply the gel, simply apply it as soon as you remember — unless it is nearly time for your next scheduled application, in which case skip the missed dose and continue as normal. Do not apply a double amount to make up for a missed application, as this increases the risk of skin irritation. Consistency is key to seeing results with this treatment.

Can I use Acnecide 5% w/w Gel during pregnancy or while breastfeeding?

The safety of benzoyl peroxide during pregnancy and breastfeeding has not been fully established, and the available data is limited. You should speak to your GP or pharmacist before using Acnecide 5% w/w Gel if you are pregnant, planning to become pregnant, or breastfeeding. They can advise on the most appropriate acne management options for your situation.

What is the difference between Acnecide 5% Gel and Panoxyl?

Both Acnecide 5% Gel and Panoxyl contain benzoyl peroxide as their active ingredient and are used to treat acne vulgaris. The key differences lie in their formulation, excipients, and brand — Acnecide is manufactured by Galderma, while Panoxyl is a different brand. Your pharmacist can help you decide which is more suitable for your skin type.

How long can you use Acnecide 5% w/w Gel for?

Acnecide 5% w/w Gel can be used for up to 3 months when purchased over the counter. If your acne has not improved after this period, or if it worsens at any point, you should consult your GP, who may recommend a prescription-strength treatment or a different approach. Long-term use beyond 3 months should only continue under medical supervision.

Will Acnecide 5% w/w Gel bleach my clothes or bedding?

Yes — benzoyl peroxide is an oxidising agent and can bleach or discolour hair, clothing, towels, and bed linen if it comes into contact with them. Allow the gel to dry completely before dressing or going to bed, and consider using white or old pillowcases and towels while using this treatment. Avoid touching your hair immediately after application.

Can I wear make-up over Acnecide 5% w/w Gel?

Yes, you can wear make-up over the gel, but you should allow it to dry fully before applying any cosmetics. Choose non-comedogenic (non-pore-blocking) products to avoid counteracting the treatment's effects. If you are using the gel in the morning, apply it first, let it dry, then follow with a non-comedogenic moisturiser and make-up if desired.

Can I use Acnecide 5% w/w Gel on my back and chest as well as my face?

Yes — Acnecide 5% w/w Gel can be applied to acne on the face, back, and chest. Apply a thin layer to the entire affected area, not just individual spots, and follow the same instructions as for facial use. Be particularly careful to avoid contact with clothing and bed linen when treating the back and chest, as bleaching is more likely in these areas.

What are the alternatives to Acnecide 5% w/w Gel for acne?

Alternatives to Acnecide 5% w/w Gel include other topical benzoyl peroxide products (such as Panoxyl), topical retinoids (available on prescription), topical antibiotics (prescription only), and azelaic acid preparations. For more severe or persistent acne, your GP may consider oral antibiotics or hormonal treatments. You can explore a range of topical options in our creams and ointments collection.

What are the latest studies on benzoyl peroxide for acne treatment?

Benzoyl peroxide remains one of the most well-evidenced topical treatments for acne, with decades of clinical research supporting its use. Current guidelines from NICE and the NHS continue to recommend it as a first-line treatment for mild to moderate acne, particularly because it does not contribute to antibiotic resistance — a growing concern in dermatology. Research continues to explore combination formulations, but 5% benzoyl peroxide monotherapy remains a clinically sound and widely recommended option.

How Should You Use Acnecide 5% w/w Gel?

Using Acnecide 5% w/w Gel correctly makes a real difference to how well it works and how well your skin tolerates it. Always read the patient information leaflet supplied with your product before starting treatment, and follow the steps below carefully.

Start with once-daily application in the evening for the first week. This allows your skin to adjust gradually and reduces the likelihood of excessive dryness or irritation.

What Is the Correct Dose of Acnecide 5% w/w Gel?

The correct dose depends on your age and how well your skin tolerates the treatment. Always start at the lower end of the dosing schedule and increase only if your skin is comfortable.

Do not apply more than a thin layer at each application. Using more gel does not improve results and significantly increases the risk of skin dryness and irritation.

When Is the Best Time to Use Acnecide 5% w/w Gel?

For the first week of treatment, apply the gel once daily in the evening, after cleansing. Evening application is generally preferred because it reduces the chance of the gel interacting with sunlight, cosmetics, or sweat during the day. After the first week, if your skin is tolerating the treatment well, you can add a morning application — making sure to allow the gel to dry before applying any sunscreen or make-up. Always use a non-comedogenic, broad-spectrum SPF during the day, as benzoyl peroxide can make skin more sensitive to UV radiation.

How Long Can You Use Acnecide 5% w/w Gel For?

Customer Reviews

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D
Daisy

I have never been wowed by an online shop like cured pharmacy. There was a barter with the delivery of the product I ordered for. During the delivery process I experienced friendly staff, professional and high quality standard of work from the staff who made sure I got the product I ordered for. Product was delivered the same day I was promised and well packaged.I am very happy to recommend Cured pharmacy to anyone looking for a top notch pharmaceutical service. Soon I will be re-ordering, please keep up the good work.

D
Daisy

I have never been wowed by an online shop like cured pharmacy. There was a barter with the delivery of the product I ordered for. During the delivery process I experienced friendly staff, professional and high quality standard of work from the staff who made sure I got the product I ordered for. Product was delivered the same day I was promised and well packaged. I am very happy to recommend Cured pharmacy to anyone looking for a top notch pharmaceutical service. Soon I will be re-ordering, please keep up the good work.

S
Seher-un-nisa
Really good item

Amazing product. Cleared my face spots.

What Are the Most Common Side Effects of Acnecide 5% w/w Gel?

Most side effects associated with Acnecide 5% w/w Gel are localised to the skin at the site of application and are generally mild. They are most likely to occur during the first few weeks of treatment as your skin adjusts to benzoyl peroxide. These effects often improve with continued use.

  • Skin dryness and flaking or peeling
  • Redness (erythema) of the treated area
  • Mild burning or stinging sensation immediately after application
  • Skin tightness or a feeling of warmth at the application site

What Are the Less Common Side Effects of Acnecide 5% w/w Gel?

Less common side effects occur in a smaller proportion of users and may require you to reduce the frequency of application or stop treatment altogether. If any of the following persist or worsen, speak to your pharmacist or GP.

  • Contact dermatitis — an allergic skin reaction causing itching, swelling, and redness beyond the application site
  • Oedema (localised swelling) at the treated area
  • Blistering or severe skin peeling
  • Skin discolouration at the application site

What Are the Serious Side Effects of Acnecide 5% w/w Gel?

Serious side effects are rare but require immediate medical attention. Stop using the gel straight away and seek urgent help if you experience any of the following signs of a severe allergic reaction (anaphylaxis or angioedema):

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • A widespread skin rash, hives, or severe itching across the body
  • Dizziness or feeling faint

What Should You Do If You Experience Side Effects of Acnecide 5% w/w Gel?

For mild side effects such as dryness and redness, try reducing application to once daily and use a gentle, non-comedogenic moisturiser after the gel has dried. Avoid using other potentially irritating products — such as exfoliants, toners containing alcohol, or other acne treatments — at the same time. If side effects are moderate or do not improve within two weeks of reducing frequency, stop use and consult your pharmacist. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Acnecide 5% w/w Gel Interact With Other Medicines?

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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