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Pyrocalm 20mg

Pyrocalm 20mg

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  • ✔️ Reduces stomach acid production for up to 24 hours
  • ✔️ Relieves heartburn and acid reflux symptoms effectively
  • ✔️ Once-daily gastro-resistant tablet — easy to swallow
  • ✔️ Suitable for adults 18+ without a prescription
  • ✔️ Clinically proven omeprazole 20mg active ingredient

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What Is Omeprazole 20mg and How Does Pyrocalm Help?

 

If you've ever felt that burning sensation creeping up your chest after a meal, you'll know how disruptive heartburn can be. Pyrocalm 20mg is an over-the-counter medicine containing omeprazole 20mg, a well-established proton pump inhibitor (PPI) used to relieve the symptoms of heartburn, acid reflux, and acid-related indigestion in adults. Available from Cured Pharmacy for just £8.49, it offers a clinically recognised option for short-term symptom relief without needing a prescription. If you're also managing other digestive concerns, you might find our indigestion range useful alongside this product.

Acid reflux occurs when stomach acid flows back up into the oesophagus, causing that familiar burning discomfort. According to the NHS, heartburn and acid reflux are very common — affecting around one in five people at some point. Pyrocalm 20mg is designed specifically for adults aged 18 and over who experience these symptoms regularly and need reliable, short-term relief.

 

How Does Pyrocalm 20mg Work to Reduce Stomach Acid?

 

Pyrocalm 20mg works by targeting the root cause of acid-related symptoms rather than simply neutralising acid after it's already been produced. Here's how it works:

  • Omeprazole belongs to a class of medicines called proton pump inhibitors (PPIs).
  • It irreversibly blocks the hydrogen-potassium ATPase enzyme system — the so-called "proton pump" — in the stomach's parietal cells.
  • This action directly reduces the production of gastric acid at its source.
  • The result is a sustained reduction in stomach acid levels, which allows the oesophagus and stomach lining to recover from irritation.

Unlike antacids, which provide very short-term relief by neutralising existing acid, omeprazole works over a longer period. Most people notice an improvement within two to three days of starting treatment, though the full effect may take up to four days.

 

Who Is Pyrocalm 20mg Suitable For?

 

Pyrocalm 20mg is intended for adults aged 18 and over who experience frequent or recurring heartburn and acid reflux symptoms. It's particularly suited to people who find antacids don't provide enough relief, or whose symptoms return quickly after using them. That said, it's not appropriate for everyone.

Pyrocalm 20mg may be suitable if you:

  • Are aged 18 or over and experiencing heartburn at least twice a week
  • Have been previously diagnosed with acid reflux or gastro-oesophageal reflux disease (GORD)
  • Need short-term relief (up to 14 days) without a prescription
  • Are not currently taking medicines known to interact with omeprazole (see Section 2 for details)

It is not suitable for children under 18, people with known hypersensitivity to omeprazole or other PPIs, or those with certain serious underlying conditions. Always read the label carefully before use.

 

How Does Pyrocalm 20mg Compare to Other Heartburn Treatments?

 

Feature Pyrocalm 20mg (Omeprazole) Antacids (e.g. Gaviscon)
Mechanism Reduces acid production at source Neutralises existing stomach acid
Onset of action 2–4 days for full effect Within minutes
Duration of relief Up to 24 hours per dose 1–3 hours typically
Suitable for frequent symptoms Yes — once daily dosing Better for occasional symptoms

 

How Should You Store Pyrocalm 20mg and Is It Clinically Appropriate for You?

 

Store Pyrocalm 20mg below 25°C in a dry place, away from direct sunlight and out of the reach of children. Do not use after the expiry date printed on the packaging. The tablets should be kept in their original blister pack until use.

Before starting omeprazole 20mg, it's worth considering whether your symptoms might indicate something more serious. The NHS advises that you should see a GP if you have difficulty swallowing, unexplained weight loss, persistent vomiting, or if you are over 55 with new or recently changed symptoms — as these could require further investigation. For those managing broader gut health, our IBS and cramps collection may also be of interest.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Pyrocalm 20mg specifications
Treatment category Acid reflux, heartburn, indigestion
Mechanism of action Proton pump inhibitor — reduces gastric acid secretion
Effective for Heartburn, acid reflux, acid-related indigestion
Suitable for Adults aged 18 and over
Active ingredient Omeprazole 20mg
Strengths 20mg
UK classification Pharmacy (P) medicine
Drug class Proton pump inhibitor (PPI)
Preparation Gastro-resistant tablet
Route of administration Oral

Specifications of Pyrocalm 20mg

 

What Is Pyrocalm 20mg and What Is It Used For?

 

Pyrocalm 20mg is a gastro-resistant tablet containing omeprazole, a proton pump inhibitor (PPI). It is used to relieve the symptoms of reflux oesophagitis — the inflammation of the oesophagus caused by stomach acid — as well as heartburn and acid-related indigestion in adults aged 18 and over. It is available over the counter for short-term use of up to 14 days. If symptoms persist beyond this period, you should consult your GP, as longer-term use requires medical supervision and investigation of the underlying cause.

 

What Do You Need to Know Before Using Pyrocalm 20mg?

 

Before taking Pyrocalm 20mg, it's important to check whether it is appropriate for you. Do not take this medicine if any of the following apply:

  • You are allergic to omeprazole, any other PPI (such as lansoprazole or pantoprazole), or any of the other ingredients
  • You are under 18 years of age
  • You are taking medicines containing nelfinavir (used to treat HIV infection)
  • You have difficulty swallowing, unexplained weight loss, persistent vomiting, or blood in your vomit or stools — seek urgent medical advice
  • You have been told you have a low level of magnesium in your blood

Pyrocalm 20mg may interact with the following medicines. Tell your pharmacist or doctor if you are taking:

  • Clopidogrel (used to prevent blood clots) — omeprazole may reduce its effectiveness
  • Methotrexate (used for cancer or inflammatory conditions) — omeprazole may increase methotrexate levels in the blood
  • Warfarin or other anticoagulants — monitoring may be required
  • Antifungal medicines such as ketoconazole or itraconazole
  • Digoxin (used for heart conditions)
  • Certain HIV medicines including atazanavir and saquinavir

 

How Should You Use Pyrocalm 20mg?

 

Always take Pyrocalm 20mg exactly as described in this leaflet or as directed by your pharmacist. The tablets are gastro-resistant, which means they are specially coated to protect the active ingredient from stomach acid — so it's important not to crush or chew them.

  1. Take one tablet once daily, ideally 30 to 60 minutes before a meal.
  2. Swallow the tablet whole with a glass of water.
  3. Do not crush, chew, or split the tablet.
  4. Continue taking for up to 14 days, or until symptoms resolve.
  5. If symptoms do not improve after 14 days, stop taking and consult your GP.
Indication Age Group Dose Frequency
Heartburn / acid reflux Adults 18+ 20mg (1 tablet) Once daily for up to 14 days
Children under 18 Under 18 Not recommended Not applicable

 

What Are the Possible Side Effects of Pyrocalm 20mg?

 

Like all medicines, Pyrocalm 20mg can cause side effects, although not everyone gets them. Most side effects are mild and resolve on their own. If you experience any severe or persistent effects, stop taking the medicine and speak to your pharmacist or GP. You can also browse our pain relief collection if you need support managing associated discomfort.

Common side effects (may affect up to 1 in 10 people):

  • Headache
  • Diarrhoea
  • Stomach pain or discomfort
  • Nausea or vomiting
  • Constipation
  • Flatulence (wind)

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness
  • Dry mouth
  • Skin rash or itching
  • Swelling of the feet or ankles
  • Disturbed sleep
  • Feeling of tingling or numbness

 

How Should You Store Pyrocalm 20mg?

 

Correct storage helps maintain the effectiveness of Pyrocalm 20mg throughout its shelf life. Follow these storage instructions carefully:

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and moisture
  • Keep the tablets in their original blister packaging until use
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the carton
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

If you have any questions about storage or suitability, our pharmacists are always happy to help. You might also find it useful to explore our sickness and nausea collection if you're experiencing related digestive symptoms alongside your acid reflux.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Pyrocalm 20mg online in the UK?

You can buy Pyrocalm 20mg directly from Cured Pharmacy, a GPhC-registered online pharmacy, for just £8.49. It is available without a prescription for adults aged 18 and over for short-term use of up to 14 days. Simply add it to your basket and complete a short suitability check at checkout.

How does Pyrocalm 20mg work in the body?

Pyrocalm 20mg contains omeprazole, which works by irreversibly blocking the proton pumps in the stomach lining that are responsible for producing gastric acid. By reducing acid at its source, it relieves the burning discomfort of heartburn and acid reflux. Unlike antacids, which only neutralise acid already present, omeprazole provides longer-lasting relief with once-daily dosing.

How do I take Pyrocalm 20mg step by step?

Take one Pyrocalm 20mg tablet once daily, ideally 30 to 60 minutes before a meal. Swallow the tablet whole with a full glass of water — do not crush, chew, or split it, as the gastro-resistant coating is essential for the medicine to work correctly. Continue for up to 14 days, and stop if symptoms resolve sooner.

What is the correct dose of Pyrocalm 20mg for heartburn?

The recommended OTC dose for adults aged 18 and over is one 20mg tablet once daily for a maximum of 14 days. Do not take more than one tablet per day unless specifically directed by a doctor. If your symptoms have not improved after 14 days, you should consult your GP rather than continuing to self-treat.

When is the best time to take Pyrocalm 20mg?

The best time to take Pyrocalm 20mg is 30 to 60 minutes before your first meal of the day, as this is when the proton pumps are most active and the medicine can work most effectively. Taking it at the same time each day also helps you remember your dose. Consistency matters more than the exact time of day.

What are the side effects of Pyrocalm 20mg and how do I manage them?

Common side effects include headache, diarrhoea, nausea, stomach pain, constipation, and wind — most of which are mild and tend to settle within a few days. If you experience dizziness, skin rash, or swelling, stop taking the medicine and speak to your pharmacist. Serious allergic reactions are rare but require immediate medical attention.

Who should not take Pyrocalm 20mg?

Pyrocalm 20mg is not suitable for anyone under 18, people with a known allergy to omeprazole or other proton pump inhibitors, or those taking nelfinavir (an HIV medicine). You should also avoid it if you have symptoms such as difficulty swallowing, unexplained weight loss, or blood in your stools, and seek urgent medical advice instead. Always check with a pharmacist if you are unsure whether it is right for you.

What happens if I miss a dose of Pyrocalm 20mg?

If you forget to take a dose, take it as soon as you remember — unless it is almost time for your next scheduled dose, in which case simply skip the missed one. Never take two tablets at once to compensate for a missed dose. Carry on with your regular once-daily schedule as normal.

Can I take Pyrocalm 20mg with other medicines?

Pyrocalm 20mg can interact with several medicines, including clopidogrel, methotrexate, warfarin, certain antifungals, digoxin, and some HIV medicines. Always tell your pharmacist about everything you are currently taking — including herbal remedies and supplements — before starting Pyrocalm 20mg. If you're managing multiple conditions, our indigestion range includes additional options your pharmacist can help you compare.

Is Pyrocalm 20mg safe to take during pregnancy or breastfeeding?

If you are pregnant, planning to become pregnant, or breastfeeding, you should not take Pyrocalm 20mg without first speaking to your doctor or midwife. The NHS advises that omeprazole is sometimes prescribed during pregnancy when the benefits outweigh the risks, but this decision should always be made by a healthcare professional. Do not self-treat with this medicine during pregnancy.

How long can you take Pyrocalm 20mg for?

When purchased over the counter, Pyrocalm 20mg should only be used for a maximum of 14 consecutive days. If your symptoms persist after this period, you must see your GP — prolonged acid suppression without investigation can mask more serious conditions. Long-term use of PPIs is only appropriate under medical supervision.

What are the alternatives to Pyrocalm 20mg for heartburn?

Alternatives include other PPIs such as lansoprazole, H2 receptor antagonists like famotidine, and antacids such as Gaviscon or calcium carbonate preparations. Antacids work faster but provide shorter relief, making them better suited to occasional symptoms. You can explore a range of options in our indigestion collection to find what suits you best.

Can Pyrocalm 20mg be taken on an empty stomach?

Pyrocalm 20mg is most effective when taken 30 to 60 minutes before eating, so it is typically taken before a meal rather than on a completely empty stomach. Taking it before food allows the medicine to be absorbed and ready to act when the proton pumps are stimulated by eating. However, if you forget and have already eaten, take it as soon as you remember.

Does Pyrocalm 20mg help with stomach ulcers?

Omeprazole — the active ingredient in Pyrocalm 20mg — is used medically to treat stomach and duodenal ulcers, but this is typically done under prescription and at doses or durations determined by a doctor. The OTC version is intended only for heartburn and acid reflux relief in adults. If you suspect you have a stomach ulcer, you should see your GP rather than self-treating.

What are the latest findings on long-term omeprazole use?

Research has highlighted that long-term PPI use may be associated with a small increased risk of hypomagnesaemia (low magnesium), vitamin B12 deficiency, and bone fractures, particularly in older adults. These risks are generally relevant to prolonged prescription use rather than short-term OTC courses of up to 14 days. The NHS and BNF recommend that long-term PPI use should always be reviewed regularly by a doctor.

How Should You Use Pyrocalm 20mg?

Using Pyrocalm 20mg correctly is straightforward, but there are a few important steps to follow to get the most from your treatment. The tablets have a special gastro-resistant coating that protects the active ingredient from being broken down by stomach acid before it reaches the intestine — so how you take them really does matter.

Follow these steps each time you take your dose:

What Is the Correct Dose of Pyrocalm 20mg?

The standard over-the-counter dose for adults is one 20mg tablet once daily. This is the only dose approved for self-treatment without a prescription. Do not increase your dose or take additional tablets, even if your symptoms feel severe — instead, speak to your GP.

When Is the Best Time to Use Pyrocalm 20mg?

The most effective time to take Pyrocalm 20mg is 30 to 60 minutes before your first meal of the day. This timing matters because omeprazole works on proton pumps that are activated when you eat — taking the tablet before food means the medicine is already absorbed and active when your stomach starts producing acid in response to eating. Taking it at a consistent time each morning also helps you build a routine and reduces the chance of missing a dose.

If you occasionally eat late or skip breakfast, try to take your tablet before your largest meal of the day instead. Avoid taking it immediately after eating, as this reduces its effectiveness.

How Long Can You Use Pyrocalm 20mg For?

Pyrocalm 20mg is intended for short-term use only when purchased over the counter. You should take it for no longer than 14 consecutive days without consulting a doctor. If your symptoms improve before 14 days, you can stop taking it earlier — there is no need to complete the full course if you feel better.

If your symptoms return after a completed course, or if they do not improve within 14 days, this is a sign that you need a medical review. Persistent acid reflux can sometimes indicate an underlying condition that requires investigation, such as gastro-oesophageal reflux disease (GORD) or a hiatus hernia. Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Pyrocalm 20mg?

Most people who take Pyrocalm 20mg tolerate it well, and side effects are generally mild. Common side effects affect up to 1 in 10 people and usually settle on their own within a few days of starting treatment. If they persist or become bothersome, speak to your pharmacist.

  • Headache
  • Diarrhoea
  • Nausea or vomiting
  • Stomach pain or discomfort
  • Constipation
  • Flatulence (wind)

What Are the Less Common Side Effects of Pyrocalm 20mg?

Less common side effects affect up to 1 in 100 people. These are not usually serious, but you should mention them to your pharmacist if they are troubling you or do not resolve.

  • Dizziness or feeling lightheaded
  • Dry mouth
  • Skin rash, itching, or hives
  • Swelling of the feet or ankles
  • Disturbed sleep or insomnia
  • Tingling or numbness in the hands or feet
  • Raised liver enzymes (detected on blood tests)

What Are the Serious Side Effects of Pyrocalm 20mg?

Serious side effects are rare but require prompt medical attention. Stop taking Pyrocalm 20mg immediately and seek urgent help if you experience any of the following:

  • Signs of a severe allergic reaction — swelling of the face, lips, tongue, or throat; difficulty breathing; or a widespread skin rash
  • Severe skin reactions such as blistering or peeling (Stevens-Johnson syndrome — very rare)
  • Muscle weakness, irregular heartbeat, or muscle cramps — these may indicate low magnesium levels (hypomagnesaemia), particularly with prolonged use
  • Severe or persistent diarrhoea, which may indicate a Clostridioides difficile infection

What Should You Do If You Experience Side Effects of Pyrocalm 20mg?

For mild side effects, you can usually continue taking Pyrocalm 20mg and allow a few days for your body to adjust. Drinking plenty of water and taking the tablet before food can help reduce nausea and stomach discomfort. If a side effect is severe, worsening, or does not improve after a few days, stop taking the medicine and consult your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Pyrocalm 20mg Interact With Other Medicines?

Yes — omeprazole can interact with a number of medicines, which is why it's important to tell your pharmacist about everything you are currently taking. Key interactions include clopidogrel (where omeprazole may reduce its antiplatelet effect), methotrexate (where omeprazole may increase blood levels), warfarin, certain antifungals, digoxin, and some HIV antiretrovirals. These interactions can affect how well your other medicines work or increase the risk of side effects. Always seek pharmacist advice before combining Pyrocalm 20mg with other treatments. If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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