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Octenisan Antimicrobial Wash Lotion 500ml - Schulke

Octenisan Antimicrobial Wash Lotion 500ml - Schulke

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  • ✔️ Kills MRSA and broad-spectrum bacteria on skin surface
  • ✔️ Contains octenidine dihydrochloride 0.1% for proven antimicrobial action
  • ✔️ Fragrance-free and colourant-free formula suits sensitive skin
  • ✔️ Supports NHS MRSA decolonisation protocols effectively
  • ✔️ Gentle enough for daily use over a five-day course

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What Is Octenisan Antimicrobial Wash Lotion?

 

If you have been advised to use an antiseptic body wash — perhaps ahead of surgery, to manage a skin infection, or to reduce bacterial colonisation — you may have come across octenisan antimicrobial wash lotion. Made by Schulke, this 500ml topical wash contains octenidine dihydrochloride 0.1% as its active ingredient. It is widely used in both clinical and home settings across the UK for skin decolonisation, particularly in patients carrying meticillin-resistant Staphylococcus aureus (MRSA). The NHS recommends decolonisation treatment for patients identified as MRSA carriers before planned hospital admissions, and antiseptic washes form a key part of that process.

Octenisan is free from alcohol, colourants, and added fragrance, making it a gentler option for people with sensitive skin. It is available over the counter without a prescription, and you can find it alongside other first aid products at Cured Pharmacy. At just £8.99 for 500ml, it represents good value for a clinically recognised antiseptic wash.

 

How Does Octenisan Wash Lotion Work on the Skin?

 

Octenisan works through the antimicrobial action of octenidine dihydrochloride, a cationic surfactant that targets the outer membranes of microorganisms. Here is how it works in practice:

  • Octenidine binds to the negatively charged cell membranes of bacteria, fungi, and enveloped viruses.
  • This binding disrupts membrane integrity, causing leakage of cellular contents and ultimately cell death.
  • The lotion's surfactant base helps lift and remove debris, dead skin cells, and transient microorganisms during washing.
  • A contact time of approximately one minute on the skin allows the active ingredient to achieve its full antimicrobial effect before rinsing.

Octenidine has a broad spectrum of activity, covering gram-positive bacteria (including MRSA and Staphylococcus epidermidis), gram-negative bacteria, yeasts, and certain viruses. Unlike chlorhexidine-based washes, octenidine is not associated with the same level of skin sensitisation with repeated use, which is one reason it is increasingly preferred in infection prevention protocols.

 

Who Should Use Octenisan Antimicrobial Wash Lotion?

 

Octenisan is suitable for a range of patients and situations. It is most commonly recommended by GPs, infection control nurses, and hospital teams. That said, it is also available for general purchase if you feel it meets your hygiene needs. Who might benefit?

  • Patients identified as MRSA carriers preparing for elective surgery or hospital admission.
  • Individuals with recurrent skin infections caused by Staphylococcus aureus or similar organisms.
  • People with skin conditions that increase susceptibility to bacterial colonisation, such as eczema or psoriasis (under medical guidance).
  • Carers or healthcare workers seeking a thorough antiseptic hand and body wash for infection control purposes.

It is not intended as a daily cosmetic wash for the general population without clinical reason. If you are unsure whether Octenisan is right for you, speak to your pharmacist or GP before starting use.

 

How Does Octenisan Compare to Chlorhexidine Wash?

 

Feature Octenisan (Octenidine 0.1%) Chlorhexidine 4% Wash
Active ingredient Octenidine dihydrochloride 0.1% Chlorhexidine gluconate 4%
Skin sensitisation risk Lower with repeated use Higher with prolonged use
Fragrance / colourant free Yes Varies by product
Suitable for sensitive skin Generally yes May cause dryness or irritation

 

Is Octenisan Suitable for Sensitive or Broken Skin?

 

Many people asking about octenisan antimicrobial wash lotion have sensitive or compromised skin — and that is understandable. The formulation is designed to be relatively gentle, with no added fragrance or colourants that commonly trigger reactions. However, you should avoid applying it to open wounds, deep cuts, or severely broken skin unless specifically directed by a healthcare professional. If you have a known allergy to octenidine or any of the excipients listed in the product's patient information leaflet, do not use this product.

For those managing skin conditions alongside infection risk, it is worth exploring the broader range of skin care products available at Cured Pharmacy to find a complete routine that works for you. Always patch test on a small area of skin before full use if you have a history of contact dermatitis or skin sensitivity.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Octenisan Antimicrobial Wash Lotion 500ml specifications
Treatment category Antiseptic / Skin decolonisation
Mechanism of action Disrupts microbial cell membranes via octenidine dihydrochloride
Effective against Gram-positive and gram-negative bacteria, MRSA, yeasts, enveloped viruses
Suitable for Adults and children (under medical guidance for children)
Active ingredient Octenidine dihydrochloride 0.1%
Pack size 500ml
UK classification General Sale / OTC
Drug class Antiseptic / Antimicrobial surfactant
Preparation Topical wash lotion
Route of administration Topical (external skin use only)

Specifications of Octenisan Antimicrobial Wash Lotion 500ml

 

What Is Octenisan Wash Lotion and What Is It Used For?

 

Octenisan Antimicrobial Wash Lotion 500ml is a topical antiseptic body wash manufactured by Schulke. It contains octenidine dihydrochloride 0.1% as its active ingredient and is used to reduce the number of microorganisms on the skin surface. In clinical practice, it is most commonly used as part of MRSA decolonisation protocols — a process the NHS uses to reduce the risk of MRSA infection in patients before planned surgery or hospital admission. It may also be recommended for patients with recurrent skin infections or those in high-risk environments where infection control is a priority.

The lotion is applied to the skin in place of regular soap or shower gel. It is not a treatment for active systemic infections and should not be swallowed or applied to mucous membranes. If you have been prescribed or recommended this product by a healthcare professional, follow their specific instructions carefully.

 

What Do You Need to Know Before Using Octenisan Wash Lotion?

 

Before using Octenisan, there are some important safety points to be aware of. Do not use this product if any of the following apply to you:

  • You have a known allergy or hypersensitivity to octenidine dihydrochloride or any other ingredient in the formulation.
  • You have open wounds, deep cuts, or severely broken skin in the area of application (unless directed by a clinician).
  • You are using it near the eyes, ears, or mouth — contact with these areas must be avoided.
  • You are pregnant or breastfeeding — seek medical advice before use, as safety data in these groups is limited.

Regarding drug interactions, Octenisan is a topical product and systemic absorption is minimal. However, be aware of the following:

  • Avoid using alongside other topical antiseptics on the same skin area simultaneously, as combined effects are not well studied.
  • Do not mix with anionic surfactants (found in some soaps and shampoos), as these may reduce the antimicrobial activity of octenidine.

 

How Should You Use Octenisan Antimicrobial Wash Lotion?

 

Using Octenisan correctly is important to get the full benefit. Follow these steps each time you wash:

  1. Wet your skin thoroughly with warm water.
  2. Apply a sufficient amount of Octenisan lotion to the wet skin — enough to create a light lather.
  3. Gently massage the lotion over the entire body, including the scalp if directed.
  4. Leave the lotion on the skin for approximately one minute to allow the active ingredient to work.
  5. Rinse thoroughly with clean water.
  6. Pat skin dry with a clean towel. Do not share towels during a decolonisation course.

For MRSA decolonisation, your infection control team or GP will typically advise a five-day course, used daily. Always follow the specific guidance given to you. You can find further infection prevention advice alongside other first aid essentials at Cured Pharmacy.

Indication Age Group Dose Frequency
MRSA decolonisation Adults Sufficient to cover body surface Once daily for 5 days
Skin infection prevention Adults Sufficient to cover affected area As directed by clinician
Pre-operative skin preparation Adults and children (clinical guidance) As directed As directed by clinical team

 

What Are the Possible Side Effects of Octenisan Wash Lotion?

 

Octenisan is generally well tolerated, but like all topical products, it can occasionally cause unwanted effects. Most reactions are mild and resolve on stopping use.

Common side effects:

  • Mild skin dryness or tightness after washing
  • Temporary redness or mild irritation at the application site

Less common side effects:

  • Contact dermatitis (itching, rash, or blistering) — stop use immediately if this occurs
  • Stinging or burning sensation, particularly on broken or sensitive skin
  • Allergic reaction — seek urgent medical attention if you develop swelling of the face, lips, or throat, or have difficulty breathing

If you experience any persistent or worsening skin reaction, stop using Octenisan and speak to your pharmacist or GP. For those prone to skin reactions, browsing the range of creams and ointments at Cured Pharmacy may help you find suitable soothing products to use alongside your decolonisation course.

 

How Should You Store Octenisan Wash Lotion?

 

  • Store below 25°C in a cool, dry place away from direct sunlight.
  • Keep the bottle tightly closed when not in use.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the bottle.
  • Do not freeze.
  • Do not store in the bathroom if it is frequently hot and humid — a bedroom or bedroom cabinet is preferable.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Octenisan Antimicrobial Wash Lotion online in the UK?

You can buy Octenisan Antimicrobial Wash Lotion 500ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £8.99. It is available without a prescription and dispatched quickly to your door. No GP referral is needed for this over-the-counter antiseptic wash.

How does Octenisan Antimicrobial Wash Lotion work in the body?

Octenisan works on the surface of the skin rather than inside the body. Its active ingredient, octenidine dihydrochloride 0.1%, binds to and disrupts the outer membranes of bacteria, fungi, and certain viruses, causing them to break down and die. This reduces the overall microbial load on the skin, which is particularly important for preventing the spread of organisms like MRSA.

How do I use Octenisan Wash Lotion step by step?

Using Octenisan correctly takes just a few minutes:

  1. Wet your skin with warm water.
  2. Apply the lotion and lather gently over the whole body.
  3. Leave on for one minute, then rinse thoroughly.

Repeat daily for the duration advised by your healthcare professional, typically five days for MRSA decolonisation.

What is the best time of day to use Octenisan Wash Lotion?

Most healthcare professionals recommend using Octenisan in the morning shower or bath so that the skin remains as free from bacteria as possible throughout the day. If you are following a pre-operative decolonisation protocol, your clinical team may give you specific timing instructions — always follow those over general guidance. Consistency matters more than the exact time of day.

What are the side effects of Octenisan Antimicrobial Wash Lotion?

Side effects are uncommon but can include mild skin dryness, temporary redness, or a slight stinging sensation — particularly on sensitive or broken skin. In rare cases, contact dermatitis may occur, presenting as an itchy rash or blistering. If you develop any severe skin reaction or signs of an allergic response such as facial swelling or breathing difficulty, stop use immediately and seek medical attention.

How do I manage skin dryness caused by Octenisan?

If you notice skin dryness during your course of Octenisan, applying a fragrance-free, non-comedogenic moisturiser after washing and drying can help restore the skin barrier. Avoid applying moisturiser immediately before using Octenisan, as this may reduce its effectiveness. Speak to your pharmacist if dryness becomes uncomfortable — they can recommend a suitable emollient from the range of creams and ointments available.

Who is eligible to use Octenisan Antimicrobial Wash Lotion?

Octenisan is suitable for most adults and can be used in children under medical supervision. It is commonly recommended for patients identified as MRSA carriers, those with recurrent skin infections, and individuals preparing for elective surgery. People with known allergies to octenidine or any excipient in the product should not use it. If you are pregnant, breastfeeding, or have a chronic skin condition, consult your GP or pharmacist before starting.

Can I use Octenisan Wash Lotion on my face and scalp?

Yes, Octenisan can be used on the face and scalp as part of a full-body decolonisation wash, but you must take care to avoid contact with the eyes, ears, and mouth. If the lotion does get into your eyes, rinse immediately with plenty of clean water. For scalp use, apply as you would a shampoo, leave for one minute, and rinse thoroughly.

What happens if I miss a day of my Octenisan decolonisation course?

If you miss a day, simply continue with your next scheduled wash — do not double up or use extra product to compensate. Consistency across the full course is important for effective decolonisation, so try to set a daily reminder. If you miss more than one day, contact your GP or infection control nurse for advice on whether to extend the course.

What are the alternatives to Octenisan Antimicrobial Wash Lotion?

The main alternative antiseptic body wash used in MRSA decolonisation in the UK is chlorhexidine gluconate 4% (such as Hibiscrub). Chlorhexidine is effective but may cause more skin sensitisation with repeated use compared to octenidine-based products. Your GP or infection control team will advise which product is most appropriate for your situation, particularly if you have sensitive skin or a history of reactions to antiseptics.

Is Octenisan Wash Lotion safe to use if I have eczema?

People with eczema have a compromised skin barrier and are more susceptible to skin reactions from topical products. Octenisan's fragrance-free, colourant-free formulation makes it a relatively gentle option, but you should always seek advice from your GP or dermatologist before using any antiseptic wash on eczematous skin. Patch testing on a small area first is strongly advisable. The NHS provides guidance on managing eczema and skin infections together.

How long should I use Octenisan Antimicrobial Wash Lotion for?

For MRSA decolonisation, a standard course is typically five consecutive days, as recommended by NHS infection control guidelines. For other indications such as recurrent skin infections or ongoing infection prevention, your healthcare professional will advise the appropriate duration. Octenisan is not intended for indefinite daily use without clinical reason — speak to your GP if you feel you need to continue beyond the recommended period.

Can Octenisan Wash Lotion be used by children or babies?

Octenisan may be used in children when directed by a healthcare professional, but it is not recommended for routine use in infants without specific clinical guidance. The skin of young babies is thinner and more permeable, which increases the risk of absorption and irritation. Always consult your GP or paediatrician before using any antiseptic wash on a child under two years of age. You can also browse baby and toddler products at Cured Pharmacy for age-appropriate options.

Does Octenisan Wash Lotion kill MRSA?

Yes, octenidine dihydrochloride — the active ingredient in Octenisan — has demonstrated activity against MRSA (meticillin-resistant Staphylococcus aureus) in published laboratory and clinical studies. It is used as part of NHS MRSA decolonisation protocols for this reason. However, it reduces bacterial load on the skin surface and does not treat systemic MRSA infection — that requires antibiotic treatment prescribed by a doctor.

What are the latest studies on octenidine-based antiseptic washes?

Research published in peer-reviewed infection control journals has consistently shown octenidine dihydrochloride to be effective against a broad range of clinically relevant pathogens, including MRSA, Candida species, and enveloped viruses. Studies have also highlighted its favourable tolerability profile compared to chlorhexidine, particularly for patients requiring repeated or prolonged skin decolonisation. Your GP or infection control specialist can advise on the most current clinical guidance relevant to your situation.

How Should You Use Octenisan Antimicrobial Wash Lotion?

Octenisan is straightforward to use, but following the correct technique ensures you get the full antimicrobial benefit. It replaces your regular soap or shower gel for the duration of your course — do not use other soaps or body washes at the same time, as these may reduce its effectiveness.

Avoid contact with the eyes, ears, and mouth at all times. If accidental contact occurs, rinse immediately with plenty of water.

What Is the Correct Dose of Octenisan Wash Lotion?

There is no fixed measured dose for Octenisan — you apply enough to cover the skin area being treated and create a light lather. The key factor is ensuring adequate coverage and the correct one-minute contact time, not the precise volume used. The table below summarises typical usage guidance by indication and age group.

When Is the Best Time to Use Octenisan Wash Lotion?

Most healthcare professionals recommend using Octenisan during your morning shower or bath. Starting the day with a freshly decolonised skin surface helps minimise bacterial recolonisation throughout the day. If you have been given specific timing instructions as part of a pre-operative protocol — for example, washing the night before and the morning of surgery — follow those instructions precisely, as timing can be clinically important in that context.

Try to use Octenisan at roughly the same time each day to build a consistent routine. Setting a daily reminder on your phone can help you complete the full course without missing a day.

How Long Can You Use Octenisan Wash Lotion For?

For MRSA decolonisation, the standard course recommended by NHS infection control teams is five consecutive days. After completing the course, your GP or infection control nurse may arrange a follow-up swab test to confirm successful decolonisation. Octenisan is not intended for indefinite daily use as a substitute for regular soap without an ongoing clinical reason. If you feel you need to continue using it beyond the recommended period, speak to your GP or pharmacist before doing so — they can assess whether continued use is appropriate for your situation.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Octenisan Wash Lotion?

Octenisan is generally well tolerated by most people, and serious side effects are uncommon. The most frequently reported effects relate to mild skin changes, particularly with daily use over a course of several days. These are usually temporary and resolve once the course is complete.

  • Mild skin dryness or tightness after washing
  • Temporary redness or flushing at the application site
  • Slight stinging or tingling sensation, particularly on sensitive skin

What Are the Less Common Side Effects of Octenisan Wash Lotion?

A small number of people may experience more noticeable skin reactions, especially those with a history of sensitive skin, eczema, or previous reactions to antiseptic products. If any of the following occur, stop using Octenisan and seek advice from your pharmacist or GP.

  • Contact dermatitis — presenting as an itchy, red, or blistering rash at the site of application
  • Persistent burning or stinging that does not settle after rinsing
  • Skin peeling or flaking beyond normal dryness
  • Worsening of a pre-existing skin condition such as eczema or psoriasis

What Are the Serious Side Effects of Octenisan Wash Lotion?

Serious allergic reactions to Octenisan are rare but possible. Octenidine dihydrochloride has been associated with anaphylactic reactions in very rare cases, particularly when used on mucous membranes or in wound irrigation — uses for which this product is not intended. If you experience any of the following after using Octenisan, stop use immediately and call 999 or go to your nearest A&E:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Sudden widespread rash or hives across the body
  • Dizziness, rapid heartbeat, or feeling faint

What Should You Do If You Experience Side Effects of Octenisan?

For mild side effects such as dryness or temporary redness, applying a fragrance-free emollient after washing and drying can help soothe the skin. Avoid scratching irritated areas, as this can introduce further bacteria. If you develop a rash or contact dermatitis, stop using Octenisan and contact your pharmacist — they can advise on whether to continue, switch to an alternative, or refer you to your GP. You can also report suspected side effects to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Octenisan Wash Lotion Interact With Other Medicines or Products?

Octenisan is a topical product with minimal systemic absorption, so interactions with oral medicines are not expected. However, there are some product-level interactions to be aware of. Avoid using Octenisan at the same time as other topical antiseptics on the same skin area, as combined effects have not been fully studied. Anionic surfactants — found in many standard soaps, shampoos, and shower gels — can reduce the antimicrobial activity of octenidine, so do not use these products alongside Octenisan during your course. Always use Octenisan as your sole cleansing product for the duration of treatment unless your healthcare professional advises otherwise.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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