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Nurofen Express Max Strength 400mg Liquid Capsules - 20 Pack

Nurofen Express Max Strength 400mg Liquid Capsules - 20 Pack

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  • ✔️ Relieves headaches, period pain, and muscular aches fast
  • ✔️ Liquid-filled capsule absorbs faster than standard ibuprofen tablets
  • ✔️ Max strength 400mg ibuprofen dose per capsule
  • ✔️ Reduces fever as well as mild to moderate pain
  • ✔️ Suitable for adults and young people aged 12 and over

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What Are Ibuprofen 400mg Liquid Capsules Used For?

 

When pain strikes — whether it's a throbbing headache, a nagging backache, or the monthly misery of period pain — you want something that gets to work quickly. Ibuprofen 400mg liquid capsules in the form of Nurofen Express Max Strength offer exactly that. Each capsule contains ibuprofen lysine, a salt form of ibuprofen that dissolves faster in the body than standard ibuprofen tablets, meaning absorption begins sooner after you take it. For anyone who needs reliable, fast-acting relief, this 20-pack is a practical choice to keep at home or in your bag.

Ibuprofen belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It's one of the most widely used over-the-counter pain relievers in the UK, recommended by the NHS for a range of everyday painful conditions. You can explore the full range of pain relief options at Cured Pharmacy if you're looking to compare alternatives or stock up on other analgesics.

 

How Do Nurofen Express Max Strength Capsules Work?

 

Understanding how this medicine works helps you use it more confidently. Ibuprofen acts by inhibiting enzymes called cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are responsible for producing prostaglandins — chemical messengers that trigger pain, inflammation, and fever in the body. By blocking their production, ibuprofen reduces all three of those responses.

  • Ibuprofen lysine dissolves more readily in the stomach than standard ibuprofen, allowing faster entry into the bloodstream.
  • COX-1 and COX-2 inhibition reduces prostaglandin synthesis at the site of injury or inflammation.
  • Pain signals to the brain are dampened as prostaglandin levels fall.
  • Fever is reduced by acting on the hypothalamus, the brain's temperature-regulating centre.

 

Who Is Nurofen Express Max Strength 400mg Suitable For?

 

This product is suitable for adults and young people aged 12 years and over. It's particularly useful for people who need a higher-strength ibuprofen dose — 400mg rather than the standard 200mg — and who want the speed advantage of a liquid-filled capsule formulation. That said, it isn't right for everyone.

  • Adults and adolescents (12+) with mild to moderate pain
  • People experiencing headaches, dental pain, period pain, or muscular aches
  • Those with a fever who need an antipyretic (fever-reducing) medicine
  • Individuals who find standard ibuprofen tablets too slow to act

It is not suitable for children under 12, people with known NSAID hypersensitivity, or those with active gastrointestinal ulcers. If you have asthma, kidney problems, or cardiovascular disease, speak to your pharmacist or GP before use.

 

How Does Nurofen Express Max Strength Compare to Standard Ibuprofen Tablets?

 

Feature Nurofen Express Max Strength 400mg Liquid Capsules Standard Ibuprofen 400mg Tablets
Active ingredient form Ibuprofen lysine (salt form) Ibuprofen (free acid)
Absorption speed Faster — liquid-filled capsule Slower — solid tablet dissolution
Strength per dose 400mg 200mg or 400mg
Pack size (this product) 20 capsules Varies (16–84 tablets)

 

How Should You Store Nurofen Express Max Strength Capsules?

 

Store this product below 25°C in a dry place, away from direct sunlight. Keep the pack out of reach and sight of children at all times. Do not use after the expiry date printed on the packaging. If you're also managing other health conditions and keeping a medicine cabinet stocked, it's worth browsing first aid essentials at Cured Pharmacy to ensure you're prepared for a range of situations.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nurofen Express Max Strength 400mg Liquid Capsules - 20 Pack specifications
Treatment category Pain relief / Antipyretic / Anti-inflammatory
Mechanism of action COX-1 and COX-2 inhibitor (NSAID)
Effective for Headache, period pain, dental pain, muscular aches, fever
Suitable for Adults and young people aged 12 and over
Active ingredient Ibuprofen lysine equivalent to ibuprofen 400mg
Pack size 20 capsules
Strength 400mg
UK classification General Sale List (GSL)
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Liquid-filled hard capsule
Route of administration Oral

Specifications of Nurofen Express Max Strength 400mg Liquid Capsules - 20 Pack

 

What Is Nurofen Express Max Strength 400mg and What Is It Used For?

 

Nurofen Express Max Strength 400mg Liquid Capsules contain ibuprofen lysine as the active ingredient, equivalent to 400mg of ibuprofen per capsule. Ibuprofen is an NSAID used to relieve mild to moderate pain and to reduce fever. The NHS recognises ibuprofen as an effective treatment for a wide range of painful conditions in adults and children aged 12 and over.

This product is indicated for the short-term relief of headaches, dental pain, period pain (dysmenorrhoea), rheumatic and muscular pain, back pain, neuralgia, migraine, and the symptoms of colds and flu including fever. The liquid-filled capsule format is designed to allow faster absorption compared to conventional solid tablets.

 

What Do You Need to Know Before Using Nurofen Express Max Strength 400mg?

 

Do not take this medicine if any of the following apply to you:

  • You are allergic to ibuprofen, aspirin, or any other NSAID
  • You have or have had a peptic ulcer or gastrointestinal bleeding
  • You are in the third trimester of pregnancy (after 28 weeks)
  • You have severe heart failure, severe kidney disease, or severe liver disease
  • You are under 12 years of age

Speak to your pharmacist or GP before taking this medicine if you have asthma, Crohn's disease, ulcerative colitis, high blood pressure, a history of heart disease or stroke, or if you are in the first or second trimester of pregnancy. Taking ibuprofen during early pregnancy is not recommended unless advised by a doctor.

The following medicines may interact with ibuprofen:

  • Aspirin and other NSAIDs — increased risk of gastrointestinal side effects
  • Warfarin and other anticoagulants — ibuprofen may increase bleeding risk
  • SSRIs (e.g. fluoxetine, sertraline) — increased risk of gastrointestinal bleeding
  • ACE inhibitors and angiotensin II receptor antagonists — reduced antihypertensive effect
  • Diuretics — reduced diuretic effect and increased risk of kidney problems
  • Lithium — ibuprofen may increase lithium plasma levels
  • Methotrexate — ibuprofen may increase methotrexate toxicity

 

How Should You Take Nurofen Express Max Strength 400mg?

 

Always take this medicine exactly as described in this leaflet or as directed by your pharmacist. Do not exceed the stated dose.

  1. Swallow the capsule whole with a full glass of water — do not chew or crush.
  2. Take with or after food to help protect your stomach lining.
  3. Wait at least 4 hours between doses.
  4. Do not take more than 3 capsules (1,200mg ibuprofen) in any 24-hour period.
  5. Use the lowest effective dose for the shortest time necessary.
Indication Age Group Dose Frequency
Pain / Fever Adults & 12+ 1 capsule (400mg) Up to 3 times daily (every 4–6 hours)
Pain / Fever Under 12 Not suitable

If you are also managing symptoms such as stomach cramps alongside pain, you may find it helpful to look at IBS and cramp relief products at Cured Pharmacy for complementary options.

 

What Are the Possible Side Effects of Nurofen Express Max Strength 400mg?

 

Like all medicines, ibuprofen can cause side effects, although not everyone gets them. The most common ones affect the digestive system. If you experience any serious symptoms, stop taking the capsules and seek medical advice promptly.

Common side effects (may affect up to 1 in 10 people):

  • Nausea and vomiting
  • Indigestion and heartburn
  • Stomach pain or discomfort
  • Diarrhoea

Less common side effects (may affect up to 1 in 100 people):

  • Headache or dizziness
  • Skin rash or itching
  • Fluid retention (swelling of ankles or feet)
  • Raised blood pressure
  • Fatigue

Serious but rare side effects include gastrointestinal bleeding, allergic reactions (including anaphylaxis), and worsening of asthma. Seek emergency medical help immediately if you notice black or tarry stools, vomit blood, develop facial swelling, or have difficulty breathing.

 

How Should You Store Nurofen Express Max Strength 400mg?

 

  • Store below 25°C in a dry place away from direct heat and sunlight.
  • Keep in the original packaging until use.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the carton.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacist.

If you're building a well-stocked home medicine cabinet, consider pairing this product with items from our cold and flu range, as ibuprofen is commonly used alongside decongestants and throat remedies during winter illness.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nurofen Express Max Strength 400mg Liquid Capsules online in the UK?

You can buy Nurofen Express Max Strength 400mg Liquid Capsules directly from Cured Pharmacy, a GPhC-registered online pharmacy. No prescription is needed as this is an over-the-counter medicine. Simply add to your basket and choose your preferred delivery option for fast UK dispatch.

How do ibuprofen 400mg liquid capsules work in the body?

Ibuprofen works by blocking COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins — the chemicals that cause pain, inflammation, and fever. The liquid-filled capsule format means ibuprofen lysine dissolves faster than a standard solid tablet, so it enters your bloodstream more quickly. This makes it a practical choice when you need relief without delay.

How do I take Nurofen Express Max Strength 400mg step by step?

Swallow one capsule whole with a full glass of water — never chew or crush it. Take it with or after food to protect your stomach. Wait at least four hours before taking another dose, and do not exceed three capsules in any 24-hour period.

What is the correct dose of Nurofen Express Max Strength 400mg for adults?

The standard adult dose is one 400mg capsule, taken up to three times daily with at least four hours between doses. The maximum daily dose is 1,200mg (three capsules) unless a doctor advises otherwise. Always use the lowest effective dose for the shortest time needed.

What is the best time to take Nurofen Express Max Strength 400mg?

Take a capsule as soon as pain or fever begins — there is no fixed time of day, but always take it with or after food. If you are using it for period pain, starting at the first sign of discomfort tends to give the best results. Spacing doses evenly throughout the day helps maintain consistent pain relief.

What are the side effects of Nurofen Express Max Strength 400mg?

Common side effects include nausea, indigestion, stomach pain, and diarrhoea. Less commonly, you might experience headache, dizziness, skin rash, or mild fluid retention. Serious side effects such as gastrointestinal bleeding or allergic reactions are rare but require immediate medical attention if they occur.

How do I manage stomach side effects from ibuprofen 400mg capsules?

Always take ibuprofen with food or milk to reduce the risk of stomach irritation. If you regularly experience stomach discomfort with NSAIDs, speak to your GP — they may recommend a stomach-protecting medicine such as a proton pump inhibitor. Do not take ibuprofen on an empty stomach.

Who should not take Nurofen Express Max Strength 400mg?

This product is not suitable for children under 12, people allergic to ibuprofen or aspirin, those with active peptic ulcers, or anyone in the third trimester of pregnancy. People with severe heart, kidney, or liver disease should also avoid it. If you have asthma or a history of gastrointestinal problems, check with your pharmacist first.

Can I take Nurofen Express Max Strength 400mg during pregnancy?

Ibuprofen is not recommended during pregnancy, particularly from 20 weeks onwards, and is contraindicated in the third trimester (after 28 weeks). If you are pregnant or trying to conceive, speak to your GP or midwife before taking any NSAID. Paracetamol is generally considered the preferred pain reliever during pregnancy.

Can I take Nurofen Express Max Strength 400mg with other medicines?

Ibuprofen can interact with several medicines including aspirin, warfarin, SSRIs, ACE inhibitors, diuretics, lithium, and methotrexate. Always tell your pharmacist about every medicine you are taking — including herbal remedies — before starting ibuprofen. Combining ibuprofen with other NSAIDs significantly increases the risk of side effects.

What happens if I miss a dose of Nurofen Express Max Strength 400mg?

If you miss a dose and it is nearly time for your next one, simply skip the missed dose and continue as normal. Never take a double dose to make up for a missed one. Ibuprofen is taken as needed for pain or fever, so strict timing is less critical than with regular prescription medicines.

How long can I take Nurofen Express Max Strength 400mg for?

For self-treatment, the NHS advises not using ibuprofen for more than three days for fever or more than ten days for pain without consulting a doctor or pharmacist. If your symptoms persist beyond these timeframes, seek professional advice. Long-term use of NSAIDs carries increased risks and should always be medically supervised.

What are the alternatives to Nurofen Express Max Strength 400mg?

Alternatives include standard ibuprofen tablets (200mg or 400mg), paracetamol, aspirin (for adults only), or combination products containing both ibuprofen and paracetamol. The right choice depends on your medical history and the type of pain you have. You can browse the full pain relief range at Cured Pharmacy to compare options.

Is Nurofen Express Max Strength 400mg suitable for children?

No — this product is only suitable for adults and young people aged 12 and over. For younger children, age-appropriate ibuprofen suspensions or paracetamol products are available. Always check the age suitability on the packaging and consult a pharmacist if you are unsure which product is right for your child.

What are the latest studies on ibuprofen liquid capsules versus standard tablets?

Research has shown that ibuprofen lysine (the salt form used in liquid capsules) is absorbed more rapidly than standard ibuprofen free acid in solid tablet form, leading to faster onset of pain relief. Clinical studies support the use of ibuprofen lysine for conditions where quick relief is important, such as migraine and acute pain. The NHS and BNF recognise ibuprofen as a first-line analgesic for mild to moderate pain in adults. If you're also interested in supporting your overall health, explore vitamins and supplements at Cured Pharmacy.

How Should You Use Nurofen Express Max Strength 400mg Liquid Capsules?

Always take Nurofen Express Max Strength 400mg Liquid Capsules exactly as directed on the packaging or as advised by your pharmacist. Taking the capsules correctly helps you get the most effective relief while minimising the risk of side effects.

Follow these steps each time you take a dose:

What Is the Correct Dose of Nurofen Express Max Strength 400mg?

Use the lowest effective dose for the shortest time necessary to control your symptoms. Do not exceed the maximum daily dose under any circumstances without medical supervision.

When Is the Best Time to Use Nurofen Express Max Strength 400mg?

Take a capsule as soon as your symptoms begin — early intervention tends to give better results, particularly for migraine and period pain. There is no fixed time of day, but spacing your doses evenly (for example, morning, afternoon, and evening with meals) helps maintain consistent relief throughout the day.

If you are using ibuprofen for period pain, starting at the very first sign of cramping — rather than waiting until pain becomes severe — is generally more effective. For fever, take a dose when your temperature rises and you feel unwell, and monitor your temperature regularly.

How Long Can You Use Nurofen Express Max Strength 400mg For?

This product is intended for short-term use only. The NHS advises not using ibuprofen for more than three consecutive days for fever, or more than ten consecutive days for pain, without seeking advice from a doctor or pharmacist. If your symptoms do not improve within these timeframes, or if they worsen, stop taking the capsules and consult a healthcare professional.

Prolonged or regular use of NSAIDs carries increased risks of gastrointestinal, cardiovascular, and renal side effects. If you find yourself needing pain relief frequently over a longer period, speak to your GP to identify and address the underlying cause.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Nurofen Express Max Strength 400mg?

Like all NSAIDs, ibuprofen can cause side effects, though not everyone experiences them. The most frequently reported side effects affect the gastrointestinal system. Taking the capsules with food significantly reduces the likelihood of stomach-related problems.

  • Nausea and vomiting
  • Indigestion and heartburn
  • Stomach pain or discomfort
  • Diarrhoea or constipation
  • Flatulence (wind)

What Are the Less Common Side Effects of Nurofen Express Max Strength 400mg?

Some people may experience side effects that are less frequent but still worth being aware of. These typically affect fewer than 1 in 100 people and often resolve once you stop taking the medicine.

  • Headache or dizziness
  • Skin rash, itching, or hives
  • Fluid retention causing ankle or foot swelling
  • Raised blood pressure
  • Fatigue or drowsiness
  • Tinnitus (ringing in the ears)
  • Visual disturbances

What Are the Serious Side Effects of Nurofen Express Max Strength 400mg?

Serious side effects are rare but can occur, particularly with prolonged use or in people with pre-existing risk factors. You should stop taking this medicine immediately and seek urgent medical attention if you notice any of the following:

  • Black, tarry, or blood-streaked stools — a sign of gastrointestinal bleeding
  • Vomiting blood or material that looks like coffee grounds
  • Severe allergic reaction (anaphylaxis): facial swelling, difficulty breathing, rapid heartbeat
  • Worsening of asthma symptoms or new onset of wheezing
  • Chest pain, sudden weakness, or slurred speech — possible signs of a cardiovascular event
  • Significant reduction in urine output — possible sign of kidney problems
  • Severe skin reactions such as blistering or peeling

What Should You Do If You Experience Side Effects of Nurofen Express Max Strength 400mg?

For mild side effects such as nausea or indigestion, try taking the capsule with a larger meal or a full glass of milk. If stomach discomfort persists, speak to your pharmacist — they may suggest a stomach-protecting medicine to take alongside ibuprofen. Do not simply increase the dose or take the capsules more frequently in an attempt to manage side effects.

If you experience any serious or unexpected side effects, stop taking the capsules immediately and contact your GP or call NHS 111. In an emergency — such as a suspected allergic reaction or gastrointestinal bleed — call 999 or go to your nearest A&E department without delay.

Can Nurofen Express Max Strength 400mg Interact With Other Medicines?

Ibuprofen has a number of clinically significant drug interactions that you should be aware of before starting treatment. Taking ibuprofen alongside aspirin (unless low-dose aspirin prescribed by a doctor) increases the risk of gastrointestinal side effects and may reduce aspirin's antiplatelet effect. Combining ibuprofen with warfarin or other anticoagulants raises the risk of bleeding. SSRIs taken with ibuprofen further increase the risk of gastrointestinal bleeding. ACE inhibitors, angiotensin II receptor antagonists, and diuretics may have their effects reduced by ibuprofen, and the combination can also impair kidney function. Ibuprofen can raise plasma levels of lithium and increase the toxicity of methotrexate. Always inform your pharmacist or GP of every medicine you are taking — including over-the-counter products and herbal supplements — before starting ibuprofen.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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