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Night Nurse Capsules - 10

Night Nurse Capsules - 10

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  • ✔️ Relieves cold and flu symptoms overnight for restful sleep
  • ✔️ Contains paracetamol to reduce fever and ease body aches
  • ✔️ Promethazine suppresses congestion and aids natural sleep
  • ✔️ Dextromethorphan calms persistent night-time cough effectively
  • ✔️ Suitable for adults and those aged 16 and over

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What Are Night Nurse Capsules and How Do They Help?

 

When a cold or flu hits at night, it can feel relentless. The blocked nose, the nagging cough, the aching limbs — all conspiring to keep you awake when your body needs rest most. Night Nurse Capsules are a well-established, GSK-manufactured combination remedy designed specifically to tackle those night-time cold and flu symptoms so you can actually get some sleep. Each pack contains 10 capsules, making it a practical option to keep in your medicine cabinet during the colder months. You can browse the full range of cold and flu treatments at Cured Pharmacy if you want to compare your options.

This is an over-the-counter (OTC) medicine, meaning you don't need a prescription to buy it. It's classified as a P (Pharmacy) medicine in the UK, so it's sold under pharmacist supervision. At £9.99 for 10 capsules, it represents a straightforward, accessible option for adults who need relief from multiple symptoms at once.

 

How Do Night Nurse Capsules Work in the Body?

 

Night Nurse Capsules work through a combination of three active ingredients, each targeting a different symptom. This multi-action approach is what makes them particularly useful when you're dealing with several complaints at once.

  • Paracetamol (500mg): Reduces fever and relieves aches and pains associated with colds and flu.
  • Promethazine hydrochloride (10mg): An antihistamine that helps relieve nasal congestion and runny nose, and causes sedation to help you sleep.
  • Dextromethorphan hydrobromide (7.5mg): A cough suppressant (antitussive) that acts on the cough centre in the brain to reduce the urge to cough.

Together, these three ingredients address the most disruptive night-time cold symptoms simultaneously. The sedative effect of promethazine is intentional here — it's not a side effect to worry about, it's part of the therapeutic design.

 

Who Is Night Nurse Capsules Suitable For?

 

Night Nurse Capsules are intended for adults and young people aged 16 and over who are experiencing cold or flu symptoms that are disrupting their sleep. They're particularly useful if you're dealing with more than one symptom at the same time — for instance, a cough alongside a fever and congestion.

  • Adults aged 16 and over with cold or flu symptoms
  • People experiencing night-time cough that disrupts sleep
  • Those with fever, aches, and nasal congestion occurring together
  • Individuals who want a single capsule to address multiple symptoms

They are not suitable for children under 16, pregnant or breastfeeding women, or people with certain medical conditions. See the patient information section below for a full list of contraindications.

 

How Do Night Nurse Capsules Compare to Night Nurse Liquid?

 

Feature Night Nurse Capsules (10) Night Nurse Liquid
Form Hard capsule Oral liquid
Active ingredients Paracetamol, Promethazine, Dextromethorphan Paracetamol, Promethazine, Dextromethorphan
Suitable for Adults and those aged 16+ Adults and those aged 16+
Convenience Pre-measured, portable Requires measuring spoon

 

How Should You Store Night Nurse Capsules?

 

Store Night Nurse Capsules below 25°C in a dry place, away from direct sunlight. Keep them out of reach and sight of children at all times. Do not use the capsules after the expiry date printed on the packaging. If you're also managing other symptoms like sore throat or body pain, you might find our pain relief collection useful alongside your cold treatment plan.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Night Nurse Capsules 10 specifications
Treatment category Cold and flu / Cough remedies
Mechanism of action Analgesic/antipyretic (paracetamol), antihistamine/sedative (promethazine), cough suppressant (dextromethorphan)
Effective for Night-time cold and flu symptoms including cough, fever, aches, and congestion
Suitable for Adults and young people aged 16 and over
Active ingredients Paracetamol 500mg, Promethazine hydrochloride 10mg, Dextromethorphan hydrobromide 7.5mg
Pack size 10 capsules
UK classification P (Pharmacy medicine)
Drug class Combination analgesic / antihistamine / antitussive
Preparation Hard capsule
Route of administration Oral

Specifications of Night Nurse Capsules 10

 

What Are Night Nurse Capsules and What Are They Used For?

 

Night Nurse Capsules are a combination OTC medicine used to relieve the symptoms of colds and flu at night. They contain three active ingredients — paracetamol, promethazine hydrochloride, and dextromethorphan hydrobromide — which work together to reduce fever, ease aches and pains, suppress coughing, relieve nasal congestion, and promote sleep. They are intended for short-term use only, taken once at bedtime during the acute phase of a cold or flu.

 

What Do You Need to Know Before Using Night Nurse Capsules?

 

Before taking these capsules, it's important to check whether they are appropriate for you. Do not take Night Nurse Capsules if any of the following apply:

  • You are under 16 years of age
  • You are pregnant or breastfeeding
  • You have liver or kidney disease
  • You have epilepsy or a history of seizures
  • You have glaucoma (raised pressure in the eye)
  • You have an enlarged prostate or difficulty passing urine
  • You are taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days
  • You have a known allergy to any of the active or inactive ingredients
  • You have a chronic cough associated with asthma or excessive phlegm

The following medicines may interact with Night Nurse Capsules. Always tell your pharmacist or doctor what you are currently taking:

  • Other paracetamol-containing products (risk of overdose)
  • Sedatives, sleeping tablets, or tranquillisers (increased drowsiness)
  • Antidepressants, particularly MAOIs and SSRIs
  • Anticoagulants such as warfarin (paracetamol may affect INR with prolonged use)
  • Other antihistamines
  • Alcohol (significantly increases sedation — avoid completely)

 

How Should You Use Night Nurse Capsules Correctly?

 

Always read the patient information leaflet supplied with your pack before taking this medicine. Follow these steps carefully:

  1. Check the expiry date on the packaging before use.
  2. Take two capsules at bedtime only — do not take during the day.
  3. Swallow the capsules whole with a full glass of water.
  4. Do not take more than two capsules in any 24-hour period.
  5. Do not take alongside any other paracetamol-containing product.
  6. Do not drive, operate machinery, or drink alcohol after taking.
Age Group Dose Frequency Notes
Adults and those aged 16+ 2 capsules Once at bedtime Do not exceed 2 capsules in 24 hours
Under 16 years Not suitable Do not use in children

If your symptoms persist for more than 5 days, or worsen significantly, stop taking the capsules and consult your GP. You may also find it helpful to explore our ear, nose and throat remedies if congestion remains a problem after your cold has passed.

 

What Are the Possible Side Effects of Night Nurse Capsules?

 

Like all medicines, Night Nurse Capsules can cause side effects, although not everyone experiences them. The sedative effect of promethazine is expected and intentional, but other effects listed below should be monitored.

Common side effects:

  • Drowsiness and sedation (intended therapeutic effect)
  • Dry mouth
  • Dizziness
  • Blurred vision
  • Constipation

Less common side effects:

  • Urinary retention (difficulty passing urine)
  • Skin rashes or photosensitivity
  • Nausea or stomach upset
  • Confusion, particularly in older adults
  • Paradoxical excitability (restlessness rather than sedation — more common in children, which is one reason this product is not for under-16s)

Stop taking the capsules and seek medical advice immediately if you experience signs of a serious allergic reaction, such as swelling of the face, lips, or throat, difficulty breathing, or a severe skin rash. Paracetamol overdose is a medical emergency — if you suspect you or someone else has taken too much, go to A&E immediately even if you feel well, as liver damage may not be apparent for several days.

 

How Should You Store Night Nurse Capsules Safely?

 

  • Store below 25°C in a dry place away from direct heat and sunlight
  • Keep out of reach and sight of children at all times
  • Do not use after the expiry date printed on the carton
  • Do not store in a bathroom or near a sink where moisture may affect the capsules
  • Do not transfer capsules to another container — keep in original blister packaging

If you need to dispose of unused capsules, return them to your local pharmacy. Do not flush medicines down the toilet or throw them in household waste. If you're looking to support your recovery more broadly, our vitamins and supplements range includes immune-support options that may be useful during and after illness.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Night Nurse Capsules online in the UK?

You can buy Night Nurse Capsules 10 online from Cured Pharmacy, a GPhC-registered UK online pharmacy, without a prescription. They are available as a Pharmacy (P) medicine and can be ordered conveniently from our cold and flu collection. Simply add to basket and complete a short health questionnaire at checkout.

How do Night Nurse Capsules work in the body?

Night Nurse Capsules contain three active ingredients that each target a different symptom. Paracetamol reduces fever and relieves aches, dextromethorphan suppresses the cough reflex by acting on the brain's cough centre, and promethazine is an antihistamine that relieves congestion and causes sedation to help you sleep. Together they provide multi-symptom relief in a single bedtime dose.

How do I take Night Nurse Capsules step by step?

Take two capsules at bedtime with a full glass of water — this is the only dose you should take in a 24-hour period. Swallow them whole and do not crush or chew. Make sure you are ready to go to bed before taking them, as the sedative effect can begin relatively quickly.

What is the correct dose of Night Nurse Capsules for adults?

The recommended dose for adults and young people aged 16 and over is two capsules taken once at bedtime. Do not take more than two capsules in any 24-hour period, and never take them alongside other paracetamol-containing medicines. Night Nurse Capsules are not suitable for anyone under 16 years of age.

Can Night Nurse Capsules cause drowsiness the next morning?

Yes, some people do experience residual drowsiness the morning after taking Night Nurse Capsules, particularly if they have taken them late at night or are sensitive to antihistamines. You should not drive or operate machinery until you are sure the effects have fully worn off. If morning drowsiness is a concern, speak to your pharmacist about alternative options.

Who should not take Night Nurse Capsules?

Night Nurse Capsules are not suitable for children under 16, pregnant or breastfeeding women, people with liver or kidney disease, those with glaucoma or an enlarged prostate, or anyone taking MAOIs. People with asthma or a productive cough with excessive phlegm should also avoid them. Always check with a pharmacist if you are unsure whether this medicine is right for you.

Can I drink alcohol while taking Night Nurse Capsules?

No — you must not drink alcohol while taking Night Nurse Capsules. Alcohol significantly increases the sedative effect of promethazine, which can be dangerous. It can also increase the risk of liver damage when combined with paracetamol. Avoid alcohol completely on any night you take these capsules.

What happens if I accidentally take too many Night Nurse Capsules?

If you take more than the recommended dose, seek medical attention immediately — even if you feel well. Paracetamol overdose can cause serious liver damage that may not be apparent for several days. Go to your nearest A&E or call 999 and tell them what you have taken. Do not wait for symptoms to appear.

What are the alternatives to Night Nurse Capsules?

Alternatives for night-time cold and flu relief include Night Nurse Liquid (same active ingredients in liquid form), Lemsip Max Night, and Benylin Night Tablets. If your main concern is pain and fever rather than sleep, you might also consider products from our pain relief range. Your pharmacist can help you choose the most appropriate option based on your specific symptoms.

How long can I take Night Nurse Capsules for?

Night Nurse Capsules are intended for short-term use only — typically no more than 5 consecutive nights. If your symptoms have not improved after 5 days, or if they worsen at any point, stop taking the capsules and consult your GP. Prolonged use of antihistamines and cough suppressants without medical supervision is not recommended.

Can I take Night Nurse Capsules if I am pregnant?

No, Night Nurse Capsules are not recommended during pregnancy. Promethazine and dextromethorphan have not been established as safe for use in pregnancy, and you should always consult your GP or midwife before taking any medicine while pregnant. There may be safer alternatives your healthcare provider can recommend for managing cold symptoms during pregnancy.

Can Night Nurse Capsules be taken with other cold medicines?

You should not take Night Nurse Capsules alongside any other product containing paracetamol, as this significantly increases the risk of paracetamol overdose. Avoid combining them with other antihistamines, cough suppressants, or sedating medicines. Always check the ingredients of any other cold remedy before taking it at the same time.

Are Night Nurse Capsules suitable for older adults?

Older adults can take Night Nurse Capsules, but they should do so with caution. Promethazine can cause increased confusion, dizziness, and urinary retention in elderly patients, which raises the risk of falls. It is advisable for older adults to speak to their GP or pharmacist before using this product, particularly if they are taking other regular medicines.

What is the difference between Night Nurse Capsules and Night Nurse Liquid?

Both products contain the same three active ingredients at equivalent doses and are used for the same purpose. The main difference is the form — capsules are pre-measured and more portable, while the liquid requires measuring with a spoon. Some people find capsules easier to take, while others prefer liquid if they have difficulty swallowing. Both are suitable for adults and those aged 16 and over.

What are the latest recommendations on treating cold and flu symptoms at night?

The NHS advises that most cold and flu symptoms can be managed at home with rest, fluids, and OTC medicines to relieve specific symptoms. Combination night-time remedies like Night Nurse Capsules are considered appropriate for short-term symptom relief in adults. Antibiotics are not effective against viral infections like colds and flu, so OTC symptom management remains the standard approach for otherwise healthy adults.

How Should You Use Night Nurse Capsules?

Night Nurse Capsules are straightforward to take, but it's important to follow the instructions carefully to use them safely and get the most benefit. Always read the patient information leaflet included in the pack before you start. These capsules are taken at bedtime only — they are not a daytime remedy.

What Is the Correct Dose of Night Nurse Capsules?

The dose is fixed for all eligible adults and does not vary based on symptom severity. Taking more than the recommended dose does not improve symptom relief and significantly increases the risk of harm, particularly from the paracetamol component.

When Is the Best Time to Use Night Nurse Capsules?

Night Nurse Capsules should always be taken at bedtime — this is not optional. The promethazine component causes sedation, which is intentional to help you sleep through your symptoms. Taking them at any other time of day is unsafe, as you would be at risk of drowsiness while going about your daily activities. Plan to take them when you are already in bed or about to get into bed for the night.

Avoid taking them if you need to be alert within the next several hours, for example if you are on call or have an early morning commitment that requires driving.

How Long Can You Use Night Nurse Capsules For?

Night Nurse Capsules are designed for short-term use only. You should not take them for more than 5 consecutive nights without speaking to a doctor or pharmacist. Cold and flu symptoms typically begin to improve within a few days, and continued use beyond this period is not recommended without medical advice.

If your symptoms persist beyond 5 days, worsen significantly, or you develop a high fever, chest pain, or shortness of breath, stop taking the capsules and seek medical attention promptly. These could be signs of a secondary infection such as pneumonia that requires different treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Night Nurse Capsules?

The most frequently reported side effects of Night Nurse Capsules are related to the promethazine component, which has sedative and anticholinergic properties. These effects are generally mild and expected given the medicine's intended action.

  • Drowsiness and sedation (this is an intended effect)
  • Dry mouth
  • Dizziness or light-headedness
  • Blurred vision
  • Constipation

What Are the Less Common Side Effects of Night Nurse Capsules?

Some people experience less common side effects that, while not dangerous in most cases, can be uncomfortable or disruptive. If any of the following persist or concern you, speak to your pharmacist.

  • Difficulty passing urine (urinary retention)
  • Nausea or stomach discomfort
  • Skin rash or increased sensitivity to sunlight (photosensitivity)
  • Confusion or disorientation, particularly in older adults
  • Headache
  • Restlessness or paradoxical excitability (more likely in children — another reason this product is not for under-16s)

What Are the Serious Side Effects of Night Nurse Capsules?

Serious side effects are rare but require immediate medical attention. Stop taking Night Nurse Capsules and seek urgent help if you experience any of the following:

  • Signs of a severe allergic reaction: swelling of the face, lips, tongue, or throat; difficulty breathing; severe skin rash or hives
  • Severe skin reactions such as blistering or peeling
  • Yellowing of the skin or eyes (jaundice), which may indicate liver problems
  • Irregular or fast heartbeat (palpitations)
  • Seizures

Paracetamol overdose is a medical emergency. If you suspect you or someone else has taken too much, go to A&E immediately — even if you feel well. Liver damage from paracetamol overdose may not be apparent for several days.

What Should You Do If You Experience Side Effects of Night Nurse Capsules?

For mild side effects such as dry mouth or dizziness, these often resolve on their own and do not require you to stop taking the medicine. Staying well hydrated can help with dry mouth. If drowsiness persists into the following day and affects your ability to function safely, do not drive or operate machinery and consider speaking to your pharmacist about whether this product is suitable for you.

You can report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve medicine safety for everyone.

Can Night Nurse Capsules Interact With Other Medicines?

Yes — Night Nurse Capsules have several clinically significant interactions. The most important is with other paracetamol-containing products, which can lead to accidental overdose. Promethazine interacts with sedatives, sleeping tablets, antidepressants (particularly MAOIs and SSRIs), and alcohol, all of which increase sedation to potentially dangerous levels. Paracetamol may also affect the anticoagulant effect of warfarin with prolonged use, so regular INR monitoring is advisable if you take both. Always tell your pharmacist or GP about all medicines, supplements, and herbal remedies you are currently taking before starting Night Nurse Capsules.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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