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Histallay Fexofenadine 120mg - 30 Tablets

Histallay Fexofenadine 120mg - 30 Tablets

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  • ✔️ Relieves hay fever sneezing, itching, and runny nose daily
  • ✔️ Non-drowsy formula – safe for driving and working
  • ✔️ Works within one to three hours of taking a tablet
  • ✔️ Suitable for adults and adolescents aged 12 and over
  • ✔️ Once-daily tablet for consistent seasonal allergy control

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What Is Fexofenadine 120mg and How Does It Help Allergies?

 

If hay fever or seasonal allergies are making your days miserable, you are not alone. Millions of people across the UK experience sneezing, itchy eyes, and a runny nose every year — particularly between March and September when pollen counts peak. Fexofenadine 120mg, sold here as Histallay, is a non-drowsy antihistamine tablet designed to tackle exactly these symptoms. It is available over the counter for adults and children aged 12 and over, and at just £8.25 for 30 tablets, it offers reliable, daily allergy relief without breaking the bank. You can explore our full range of allergy and hay fever treatments if you need additional support alongside this product.

Fexofenadine belongs to the second-generation antihistamine class. Unlike older antihistamines such as chlorphenamine, it is specifically formulated to minimise sedation — meaning you can get on with your day without feeling foggy or tired. The NHS recognises fexofenadine as one of the antihistamines least likely to cause drowsiness, which makes it a practical choice for people who drive, work, or study.

 

How Does Histallay Fexofenadine Work in the Body?

 

Allergic reactions happen when your immune system overreacts to a harmless substance — pollen, pet dander, dust mites — and releases a chemical called histamine. Histamine then binds to receptors throughout your body, triggering the familiar cascade of sneezing, itching, and inflammation. Fexofenadine works by selectively blocking H1 histamine receptors, preventing histamine from binding and causing those symptoms.

  • Fexofenadine does not cross the blood-brain barrier to any significant degree, which is why it causes far less sedation than first-generation antihistamines.
  • It reaches peak plasma concentration within one to three hours of taking a tablet.
  • It is primarily excreted unchanged in the faeces and urine, with minimal liver metabolism — making it suitable for many people who cannot tolerate medicines that are heavily metabolised.
  • The 120mg strength is specifically indicated for seasonal allergic rhinitis (hay fever) in adults and adolescents aged 12 and over.

 

Who Should Use Histallay Fexofenadine 120mg?

 

This product is suitable for a wide range of people dealing with seasonal allergy symptoms. It is particularly well-suited to those who have found older antihistamines too sedating, or who need to remain alert throughout the day. That said, it is not appropriate for everyone — always read the label and speak to a pharmacist if you are unsure.

  • Adults and adolescents aged 12 and over with seasonal allergic rhinitis (hay fever)
  • People who need a non-drowsy option for daytime allergy relief
  • Those who drive or operate machinery and cannot risk sedation
  • Individuals who have not responded adequately to other antihistamines

 

How Does Fexofenadine 120mg Compare to Other Antihistamines?

 

Feature Histallay Fexofenadine 120mg Cetirizine 10mg
Generation Second-generation Second-generation
Drowsiness risk Very low Low to moderate
Dosing frequency Once daily Once daily
Suitable age 12 years and over 6 years and over
Fruit juice interaction Yes — avoid grapefruit, orange, apple No significant interaction

 

Is Fexofenadine 120mg Safe to Store at Home?

 

Yes — Histallay fexofenadine 120mg is straightforward to store. Keep the tablets below 25°C in a dry place, away from direct sunlight and moisture. Always store medicines out of the reach and sight of children. Do not use the tablets after the expiry date printed on the packaging. If you are also managing skin-related allergy symptoms, you may find our skin care range a useful complement to antihistamine treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Histallay Fexofenadine 120mg 30 Tablets specifications
Treatment category Seasonal allergic rhinitis (hay fever)
Mechanism of action Selective H1 histamine receptor antagonist
Effective for Sneezing, runny nose, itchy and watery eyes, itchy throat
Suitable for Adults and adolescents aged 12 and over
Active ingredient Fexofenadine hydrochloride 120mg
Pack size 30 tablets
Strength 120mg
UK classification P (Pharmacy medicine)
Drug class Second-generation antihistamine
Preparation Film-coated tablet
Route of administration Oral

Specifications of Histallay Fexofenadine 120mg 30 Tablets

 

What Is Histallay Fexofenadine 120mg and What Is It Used For?

 

Histallay Fexofenadine 120mg is an over-the-counter antihistamine tablet used to relieve the symptoms of seasonal allergic rhinitis — more commonly known as hay fever. It contains fexofenadine hydrochloride, a second-generation antihistamine that works by blocking the action of histamine in the body. It is indicated for adults and adolescents aged 12 and over who experience sneezing, a runny or blocked nose, itchy eyes, watery eyes, or an itchy throat during allergy season. The NHS lists fexofenadine as one of the antihistamines that is least likely to make you feel drowsy, which is why many people prefer it for daytime use.

 

What Do You Need to Know Before Using Histallay Fexofenadine 120mg?

 

Before taking this medicine, it is important to check whether it is appropriate for you. Do not take Histallay Fexofenadine 120mg if any of the following apply:

  • You are allergic to fexofenadine hydrochloride or any other ingredient in the tablet
  • You are under 12 years of age
  • You are pregnant or breastfeeding (seek medical advice first)
  • You have severe kidney problems (renal impairment) — dose adjustment may be needed under medical supervision

The following medicines may interact with fexofenadine and should be discussed with your pharmacist or GP:

  • Antacids containing aluminium or magnesium hydroxide — take fexofenadine at least 2 hours before or after these
  • Erythromycin (an antibiotic) — may increase fexofenadine plasma levels
  • Ketoconazole (an antifungal) — may also increase fexofenadine levels in the blood
  • Fruit juices (grapefruit, orange, apple) — significantly reduce absorption; always take with water only

 

How Should You Use Histallay Fexofenadine 120mg?

 

Always take this medicine exactly as described on the label or as directed by your pharmacist. Do not exceed the stated dose.

  1. Take one tablet (120mg) once daily.
  2. Swallow the tablet whole with a full glass of water.
  3. Do not take with fruit juice — grapefruit, orange, and apple juice all reduce how much fexofenadine your body absorbs.
  4. Take at the same time each day to maintain consistent symptom control.
  5. If you are also taking an antacid, leave at least a 2-hour gap before or after taking fexofenadine.
Indication Age Group Dose Frequency
Seasonal allergic rhinitis Adults and children aged 12+ 120mg (1 tablet) Once daily
Children under 12 Under 12 years Not recommended

 

What Are the Possible Side Effects of Histallay Fexofenadine 120mg?

 

Like all medicines, fexofenadine can cause side effects, although not everyone gets them. Most people tolerate it very well. If you experience any side effects that concern you, stop taking the medicine and speak to your pharmacist or GP. You can also browse our ear, nose and throat range for additional symptom relief options.

Common side effects (may affect up to 1 in 10 people):

  • Headache
  • Nausea
  • Dizziness

Less common side effects (may affect up to 1 in 100 people):

  • Drowsiness
  • Insomnia or difficulty sleeping
  • Nervousness
  • Fatigue
  • Dry mouth

Serious allergic reactions to fexofenadine are rare. Seek immediate medical attention if you develop difficulty breathing, swelling of the face, lips, tongue or throat, or a severe skin rash.

 

How Should You Store Histallay Fexofenadine 120mg?

 

Correct storage helps maintain the effectiveness and safety of your tablets. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and moisture
  • Store in the original packaging
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the carton
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

If you are managing multiple allergy symptoms, including itchy or watery eyes, our eye care collection includes antihistamine eye drops that can be used alongside oral antihistamines for more targeted relief.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Histallay Fexofenadine 120mg online in the UK?

You can buy Histallay Fexofenadine 120mg directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as a Pharmacy (P) medicine for adults and adolescents aged 12 and over. Simply add it to your basket and it will be dispatched to your door — no GP appointment needed.

How does fexofenadine 120mg work in the body?

Fexofenadine is a selective H1 antihistamine that works by blocking histamine receptors, preventing histamine from triggering allergy symptoms such as sneezing, itching, and a runny nose. Unlike older antihistamines, it does not cross the blood-brain barrier to any significant degree, so it causes very little drowsiness. It typically starts working within one to three hours of taking a tablet.

How do I take Histallay Fexofenadine 120mg step by step?

Take one 120mg tablet once a day, swallowed whole with a full glass of water. Never take it with fruit juice — grapefruit, orange, and apple juice all reduce how much of the medicine your body absorbs. Try to take it at the same time each day for consistent symptom control throughout allergy season.

What is the best time of day to take fexofenadine 120mg?

There is no strict requirement on timing, but many people find taking it in the morning works well — especially if pollen exposure tends to peak during the day. The most important thing is consistency: taking it at the same time each day helps maintain steady levels in your bloodstream. If you find it causes any mild drowsiness, switching to an evening dose is a reasonable option.

What are the side effects of Histallay Fexofenadine 120mg and how do I manage them?

The most commonly reported side effects include headache, nausea, and dizziness — these are usually mild and tend to settle on their own. Less commonly, some people experience insomnia, fatigue, or a dry mouth. If side effects persist or feel severe, stop taking the tablets and speak to your pharmacist or GP promptly.

Who is eligible to take Histallay Fexofenadine 120mg?

This product is suitable for adults and adolescents aged 12 and over who experience seasonal allergic rhinitis symptoms. It is not recommended for children under 12, and people who are pregnant, breastfeeding, or have severe kidney problems should seek medical advice before using it. Always check with your pharmacist if you are taking other medicines, as interactions are possible.

What happens if I miss a dose of fexofenadine 120mg?

If you forget to take your tablet, take it as soon as you remember — unless it is nearly time for your next scheduled dose. In that case, simply skip the missed dose and carry on as normal. Never take two tablets at once to compensate for a missed dose, as this will not improve symptom relief and may increase the risk of side effects.

Can I take fexofenadine 120mg every day during hay fever season?

Yes — fexofenadine 120mg is designed for daily use throughout the allergy season, which in the UK typically runs from late March to September depending on which pollens affect you. The NHS advises starting antihistamines before your symptoms begin if you know your trigger season, as this can help prevent symptoms from taking hold. If you need it for longer than the allergy season, speak to your GP.

How does fexofenadine compare to cetirizine or loratadine for hay fever?

All three are second-generation antihistamines used for hay fever, but fexofenadine is generally considered the least likely to cause drowsiness among the three. Cetirizine and loratadine are also non-drowsy options, though cetirizine in particular can cause sedation in some individuals. The best choice depends on how your body responds — if one does not suit you, your pharmacist can help you switch. You can browse our full allergy and hay fever range to compare available options.

Can I drive after taking Histallay Fexofenadine 120mg?

Fexofenadine is one of the antihistamines least likely to impair driving ability, as it has a very low sedation profile. However, a small number of people may still experience dizziness or drowsiness, so it is sensible to see how the medicine affects you before driving or operating machinery. If you feel any impairment, do not drive and speak to your pharmacist.

Can I take fexofenadine 120mg with other medicines?

Fexofenadine can interact with certain medicines, including erythromycin (an antibiotic) and ketoconazole (an antifungal), both of which may increase fexofenadine levels in the blood. Antacids containing aluminium or magnesium hydroxide can reduce absorption, so leave at least a 2-hour gap if you take these. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are taking before starting fexofenadine.

Is fexofenadine 120mg safe to take during pregnancy or breastfeeding?

The safety of fexofenadine during pregnancy and breastfeeding has not been fully established, so it is not recommended without medical advice. If you are pregnant, planning to become pregnant, or breastfeeding, speak to your GP or midwife before taking any antihistamine. They can advise on the most appropriate option for your situation.

Why should I avoid fruit juice when taking fexofenadine 120mg?

Grapefruit, orange, and apple juices contain compounds that inhibit the organic anion transporting polypeptide (OATP) transporters in your gut, which are responsible for absorbing fexofenadine into your bloodstream. Drinking these juices alongside the tablet can reduce the amount of medicine your body absorbs by up to 36%, significantly reducing its effectiveness. Always take fexofenadine with plain water only.

How long does it take for fexofenadine 120mg to start working?

Fexofenadine typically reaches peak plasma concentration within one to three hours of taking a tablet, so most people notice symptom relief within a couple of hours. For best results during high-pollen days, take your tablet in the morning before heading outdoors. If you also suffer from itchy or irritated eyes, our eye care collection includes antihistamine drops that can provide faster localised relief.

What are the latest findings on fexofenadine for allergic rhinitis?

Fexofenadine has been extensively studied and is well-established in clinical guidelines as an effective, well-tolerated treatment for seasonal allergic rhinitis. Research consistently confirms its low sedation profile compared to first-generation antihistamines, and it remains a recommended option in NHS guidance for hay fever management. No major new safety concerns have emerged in recent years, reinforcing its status as a reliable daily allergy treatment.

How Should You Use Histallay Fexofenadine 120mg?

Using this medicine correctly ensures you get the most effective relief from your allergy symptoms. Always follow the instructions on the packaging or as directed by your pharmacist — do not take more than the recommended dose.

What Is the Correct Dose of Histallay Fexofenadine 120mg?

The standard dose for adults and adolescents aged 12 and over is one 120mg tablet taken once daily. Do not take more than one tablet in a 24-hour period. This product is not suitable for children under 12 years of age.

When Is the Best Time to Use Histallay Fexofenadine 120mg?

Most people find taking their tablet in the morning works well, particularly if they are exposed to pollen during the day. Taking it at a consistent time each day helps maintain steady levels of the medicine in your system, which supports more reliable symptom control throughout the day. If you experience any mild drowsiness — which is uncommon — switching to an evening dose is a reasonable alternative.

During high-pollen days, it can also help to take the tablet before you go outdoors, giving the medicine time to reach effective levels in your bloodstream before exposure begins.

How Long Can You Use Histallay Fexofenadine 120mg For?

Histallay Fexofenadine 120mg is suitable for use throughout the allergy season, which in the UK typically runs from late March to September, depending on which pollens trigger your symptoms. Many people take it daily for the duration of the season without any issues. If you find you need it year-round or for longer than one season, it is worth speaking to your GP to review your allergy management plan and rule out any underlying conditions.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Histallay Fexofenadine 120mg?

Using this medicine correctly ensures you get the most effective relief from your allergy symptoms. Always follow the instructions on the packaging or as directed by your pharmacist — do not take more than the recommended dose.

What Is the Correct Dose of Histallay Fexofenadine 120mg?

The standard dose for adults and adolescents aged 12 and over is one 120mg tablet taken once daily. Do not take more than one tablet in a 24-hour period. This product is not suitable for children under 12 years of age.

When Is the Best Time to Use Histallay Fexofenadine 120mg?

Most people find taking their tablet in the morning works well, particularly if they are exposed to pollen during the day. Taking it at a consistent time each day helps maintain steady levels of the medicine in your system, which supports more reliable symptom control throughout the day. If you experience any mild drowsiness — which is uncommon — switching to an evening dose is a reasonable alternative.

During high-pollen days, it can also help to take the tablet before you go outdoors, giving the medicine time to reach effective levels in your bloodstream before exposure begins.

How Long Can You Use Histallay Fexofenadine 120mg For?

Histallay Fexofenadine 120mg is suitable for use throughout the allergy season, which in the UK typically runs from late March to September, depending on which pollens trigger your symptoms. Many people take it daily for the duration of the season without any issues. If you find you need it year-round or for longer than one season, it is worth speaking to your GP to review your allergy management plan and rule out any underlying conditions.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Histallay Fexofenadine 120mg?

Most people who take fexofenadine tolerate it very well, and serious side effects are uncommon. That said, like all medicines, it can cause unwanted effects in some people. The most frequently reported side effects are generally mild and tend to resolve on their own without needing to stop treatment.

  • Headache
  • Nausea
  • Dizziness

What Are the Less Common Side Effects of Histallay Fexofenadine 120mg?

A smaller number of people may experience the following side effects, which occur less frequently but are still worth being aware of. If any of these bother you or do not settle within a few days, speak to your pharmacist.

  • Drowsiness or fatigue
  • Insomnia or difficulty sleeping
  • Nervousness
  • Dry mouth
  • Abdominal pain

What Are the Serious Side Effects of Histallay Fexofenadine 120mg?

Serious side effects from fexofenadine are rare, but they do require immediate medical attention if they occur. A severe allergic reaction (anaphylaxis) is the most significant risk, though it is very uncommon. You should seek emergency help straight away if you notice any of the following after taking this medicine.

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat
  • Severe skin rash, hives, or itching
  • Rapid or irregular heartbeat (palpitations)

What Should You Do If You Experience Side Effects of Histallay Fexofenadine 120mg?

If you develop mild side effects such as a headache or nausea, these often improve as your body adjusts to the medicine. Staying well hydrated and taking the tablet with food may help reduce nausea. However, if side effects are persistent, worsening, or affecting your daily life, stop taking the tablets and consult your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Histallay Fexofenadine 120mg Interact With Other Medicines?

Yes — fexofenadine can interact with certain medicines, which may affect how well it works or increase the risk of side effects. Erythromycin and ketoconazole can both raise fexofenadine levels in the blood. Antacids containing aluminium or magnesium hydroxide reduce absorption, so always leave a 2-hour gap between these and your fexofenadine dose. Fruit juices — particularly grapefruit, orange, and apple — also significantly reduce absorption and should be avoided entirely when taking this medicine. Always inform your pharmacist of all medicines, supplements, and herbal remedies you are currently taking.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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