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Piriteze One A Day Tablets

Piriteze One A Day Tablets

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  • ✔️ Provides 24-hour hay fever and allergy symptom relief
  • ✔️ Contains cetirizine 10mg, a clinically proven antihistamine
  • ✔️ Non-drowsy formula suitable for daytime use
  • ✔️ Relieves sneezing, itching, runny nose and hives
  • ✔️ Suitable for adults and children aged 6 and over

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Are Piriteze One A Day Cetirizine Allergy Tablets Right for You?

 

If sneezing fits, itchy eyes, and a constantly runny nose are making your day miserable, you are not alone. Hay fever affects around 1 in 5 people in the UK at some point in their lives, according to the NHS. Cetirizine allergy tablets like Piriteze One A Day offer a convenient, once-daily solution that gets to work quickly — so you can get on with your day without constantly reaching for a tissue. Available at Cured Pharmacy for just £3.49, this is one of the most widely used over-the-counter antihistamines in the UK. If you are managing multiple allergy symptoms, you might also want to explore our full range of allergy and hay fever treatments for additional support.

Piriteze One A Day Tablets contain cetirizine hydrochloride 10mg as the active ingredient. Cetirizine is a second-generation antihistamine, which means it is far less likely to cause the heavy drowsiness associated with older antihistamines. One tablet, once a day, provides up to 24 hours of symptom relief — making it a practical choice for people with busy lifestyles.

 

How Do Piriteze One A Day Tablets Work?

 

When your body encounters an allergen — pollen, pet dander, dust mites, for example — it releases a chemical called histamine. Histamine binds to H1 receptors throughout the body, triggering the familiar cascade of allergy symptoms: sneezing, itching, watery eyes, and nasal congestion. Cetirizine works by selectively blocking those H1 receptors, preventing histamine from causing its effects.

  • Cetirizine is absorbed rapidly after oral ingestion, with peak plasma concentration reached within one hour.
  • It has a long half-life, which is why a single daily dose provides round-the-clock coverage.
  • Unlike first-generation antihistamines, cetirizine has limited penetration of the blood-brain barrier, reducing sedation risk.
  • It relieves sneezing, itching, rhinorrhoea (runny nose), and urticaria (hives).

 

Who Should Use Piriteze One A Day Tablets?

 

These tablets are suitable for a wide range of people dealing with allergic conditions. They are particularly useful if you need all-day symptom control without the inconvenience of multiple doses. That said, they are not appropriate for everyone — always read the label and check with your pharmacist if you are unsure.

  • Adults and children aged 6 years and over with hay fever (seasonal allergic rhinitis)
  • People experiencing perennial allergic rhinitis triggered by dust mites or pet hair
  • Those with allergic skin conditions such as urticaria (hives) or itchy rashes
  • Individuals who need a non-drowsy antihistamine for daytime use

 

How Do Piriteze One A Day Tablets Compare to Other Antihistamines?

 

Feature Piriteze One A Day (Cetirizine 10mg) Piriton (Chlorphenamine 4mg)
Generation Second-generation First-generation
Dosing frequency Once daily Up to 4–6 times daily
Drowsiness risk Low High
Duration of action 24 hours 4–6 hours
Suitable for children 6 years and over 6 years and over (lower dose)

 

Is Piriteze One A Day Suitable for Long-Term Use and How Should It Be Stored?

 

Many people with perennial allergies use cetirizine allergy tablets on an ongoing basis throughout allergy season or even year-round. The NHS notes that antihistamines like cetirizine are generally well tolerated for extended use, though it is always worth reviewing your treatment with a pharmacist or GP if you have been taking them for several months. People with kidney impairment may need a reduced dose or less frequent dosing — your pharmacist can advise on this.

Store Piriteze One A Day Tablets below 25°C in a dry place, away from direct sunlight. Keep them out of reach and sight of children. Do not use after the expiry date printed on the packaging. If you are also managing eye-related allergy symptoms, our eye care range includes antihistamine eye drops that can complement your oral treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Piriteze One A Day Tablets specifications
Treatment category Allergy & Hay Fever
Active ingredient Cetirizine hydrochloride 10mg
Mechanism of action Selective H1 histamine receptor antagonist
Drug class Second-generation antihistamine
Suitable for Adults and children aged 6 years and over
Strengths 10mg
Preparation Film-coated tablet
Route of administration Oral
UK classification General Sale List (GSL)
Effective for Hay fever, allergic rhinitis, urticaria

Specifications of Piriteze One A Day Tablets

 

What Are Piriteze One A Day Tablets and What Are They Used For?

 

Piriteze One A Day Tablets are an over-the-counter antihistamine medicine containing cetirizine hydrochloride 10mg. They are used to relieve the symptoms of hay fever (seasonal allergic rhinitis), perennial allergic rhinitis, and allergic skin conditions such as urticaria. Symptoms that these tablets can help with include sneezing, a runny or blocked nose, itchy and watery eyes, and itchy skin or hives. The NHS confirms that cetirizine is one of the most commonly recommended antihistamines for hay fever and allergy relief in the UK.

 

What Do You Need to Know Before Using Piriteze One A Day Tablets?

 

Before taking these tablets, it is important to check whether they are appropriate for you. Do not take Piriteze One A Day Tablets if any of the following apply:

  • You are allergic to cetirizine hydrochloride, hydroxyzine, or any other ingredient in the tablet
  • You have severe kidney (renal) impairment
  • You are under 6 years of age
  • You are pregnant or breastfeeding — seek medical advice first
  • You have epilepsy or a condition that increases your risk of seizures

The following medicines may interact with cetirizine. Always tell your pharmacist or doctor what you are currently taking:

  • Alcohol — increases the risk of drowsiness
  • Other sedatives or CNS depressants (e.g. sleeping tablets, anxiolytics)
  • Ritonavir (used to treat HIV) — may increase cetirizine levels in the blood
  • Theophylline — may slightly reduce cetirizine clearance

 

How Should You Use Piriteze One A Day Tablets?

 

Always take Piriteze One A Day Tablets exactly as described in the patient information leaflet or as directed by your pharmacist. Do not exceed the stated dose.

  1. Take one tablet (10mg) by mouth once daily.
  2. Swallow the tablet whole with a glass of water.
  3. You can take it with or without food — it does not affect absorption significantly.
  4. Try to take it at the same time each day to maintain consistent blood levels.
  5. Do not crush or chew the tablet.
Age Group Dose Frequency Notes
Adults and children 12+ 10mg (1 tablet) Once daily Standard dose
Children 6–11 years 5mg (half tablet) Once daily Use a scored tablet or liquid formulation
Adults with mild–moderate kidney impairment 5mg Once daily Seek medical advice before use
Children under 6 Not recommended Use age-appropriate formulation on medical advice

 

What Are the Possible Side Effects of Piriteze One A Day Tablets?

 

Like all medicines, Piriteze One A Day Tablets can cause side effects, although not everyone experiences them. The NHS advises that cetirizine is generally well tolerated, but it is worth knowing what to look out for.

Common side effects (may affect up to 1 in 10 people):

  • Drowsiness or fatigue
  • Dry mouth
  • Headache
  • Dizziness
  • Gastrointestinal discomfort (nausea, stomach pain)

Less common side effects (may affect up to 1 in 100 people):

  • Agitation or restlessness
  • Paraesthesia (tingling or numbness)
  • Blurred vision
  • Urinary retention
  • Skin rash or pruritus (itching)

Rarely, cetirizine can cause a serious allergic reaction (anaphylaxis). Seek emergency medical help immediately if you develop swelling of the face, lips, tongue or throat, difficulty breathing, or a severe skin reaction. If you are also managing symptoms that affect your nose and throat, our ear, nose and throat range may offer additional relief options.

 

How Should You Store Piriteze One A Day Tablets?

 

  • Store below 25°C in a dry place, away from direct heat and sunlight
  • Keep in the original packaging to protect from moisture
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the carton or blister strip
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

If you are looking for broader allergy management support, including nasal sprays and eye drops, browse our allergy and hay fever collection for a full range of options.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Piriteze One A Day Tablets online in the UK?

You can buy Piriteze One A Day Tablets from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £3.49 — no prescription needed. They are classed as a General Sale List (GSL) medicine, meaning they are also available from supermarkets and high street pharmacies. Ordering online is a quick and discreet option, especially during peak hay fever season when shelves can sell out fast.

How do Piriteze One A Day Tablets work in the body?

Piriteze One A Day Tablets contain cetirizine hydrochloride, which works by selectively blocking H1 histamine receptors in the body. When you are exposed to an allergen such as pollen or pet dander, your immune system releases histamine — and it is histamine binding to these receptors that causes sneezing, itching, and a runny nose. By blocking those receptors, cetirizine prevents those symptoms from developing or worsens them significantly less. Because cetirizine is a second-generation antihistamine, it has limited ability to cross the blood-brain barrier, which is why it causes far less drowsiness than older antihistamines like chlorphenamine.

How do I take Piriteze One A Day Tablets step by step?

Take one tablet (10mg) once daily, swallowed whole with a glass of water. You can take it with or without food, and at any time of day that suits your routine. Try to take it at the same time each day for consistent symptom control — and never take more than one tablet in any 24-hour period.

What is the best time of day to take Piriteze One A Day Tablets?

There is no single "best" time — it really depends on when your symptoms are worst. If your allergy symptoms tend to peak in the morning, taking the tablet the evening before can mean it is already working when you wake up. If you find cetirizine makes you slightly drowsy, taking it at night is a sensible approach. The key is consistency — taking it at the same time each day helps maintain steady levels in your system.

What are the side effects of Piriteze One A Day Tablets and how do I manage them?

The most common side effects include drowsiness, dry mouth, headache, and fatigue — though many people experience no side effects at all. If drowsiness is a problem, try taking the tablet in the evening rather than the morning. Staying well hydrated can help with dry mouth. If you experience more serious symptoms such as difficulty breathing, swelling of the face or throat, or a severe skin reaction, stop taking the tablets and seek emergency medical help immediately.

Who is eligible to take Piriteze One A Day Tablets?

Piriteze One A Day Tablets are suitable for adults and children aged 6 years and over. They are not recommended for children under 6 years old, and people with severe kidney impairment should not take them without medical advice. If you are pregnant, breastfeeding, or taking other medicines, speak to your pharmacist or GP before starting treatment. You can browse our wider allergy and hay fever range if you need an alternative formulation.

What happens if I miss a dose of Piriteze One A Day Tablets?

If you forget to take your tablet, take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case simply skip the missed one. Never take two tablets at once to compensate for a missed dose. Missing the occasional dose is unlikely to cause any harm, but try to get back into your regular routine as soon as possible for consistent symptom control.

How do Piriteze One A Day Tablets compare to Piriton?

Piriteze contains cetirizine, a second-generation antihistamine, while Piriton contains chlorphenamine, a first-generation antihistamine. The key practical differences are that Piriteze only needs to be taken once a day and is much less likely to cause drowsiness, whereas Piriton may need to be taken up to four to six times daily and commonly causes sedation. For most people managing daytime hay fever or allergy symptoms, Piriteze is the more convenient and better-tolerated option.

Can I take Piriteze One A Day Tablets with other medicines?

Cetirizine can interact with certain medicines, including alcohol, sedatives, sleeping tablets, and ritonavir (used to treat HIV). Combining cetirizine with alcohol or other CNS depressants increases the risk of drowsiness and impaired reactions. Always tell your pharmacist or GP about all medicines, supplements, and herbal remedies you are taking before starting Piriteze One A Day Tablets.

Are Piriteze One A Day Tablets safe to take during pregnancy?

The safety of cetirizine during pregnancy has not been fully established, and the NHS advises that you should speak to your GP or midwife before taking any antihistamine if you are pregnant. The same applies if you are breastfeeding, as small amounts of cetirizine may pass into breast milk. Your healthcare provider can help you weigh up the risks and benefits and suggest the most appropriate option for your situation.

Can I drive after taking Piriteze One A Day Tablets?

Piriteze One A Day Tablets are classed as a non-drowsy antihistamine, but a small number of people do experience drowsiness or dizziness after taking cetirizine. You should not drive or operate heavy machinery if you feel affected in any way. It is sensible to see how the tablets affect you before driving, particularly when you first start taking them.

How long can I take Piriteze One A Day Tablets for?

Many people take cetirizine throughout the entire hay fever season, which in the UK typically runs from late March to September. Others with year-round allergies may take it continuously. The NHS notes that antihistamines like cetirizine are generally safe for longer-term use, but if you have been taking them for several months without review, it is worth checking in with your pharmacist or GP to make sure they are still the right treatment for you.

What are the alternatives to Piriteze One A Day Tablets?

Common alternatives include loratadine (e.g. Clarityn), fexofenadine (e.g. Telfast), and acrivastine (e.g. Benadryl Allergy Relief) — all second-generation antihistamines available over the counter in the UK. For people who need additional relief, nasal corticosteroid sprays such as beclometasone (e.g. Beconase) can be used alongside an antihistamine. You can explore a full selection of options in our allergy and hay fever collection.

Do Piriteze One A Day Tablets help with itchy eyes caused by hay fever?

Yes — cetirizine can help relieve itchy, watery eyes associated with allergic rhinitis and hay fever, as these symptoms are driven by histamine. However, if your eye symptoms are particularly severe or persistent, antihistamine eye drops used alongside an oral tablet may provide more targeted relief. Take a look at our eye care range for suitable options to use alongside Piriteze.

What is the latest research on cetirizine for allergy treatment?

Cetirizine has been extensively studied since its introduction in the late 1980s and remains one of the most well-evidenced antihistamines available. Current clinical guidelines from NICE and the BNF continue to recommend second-generation antihistamines like cetirizine as first-line treatment for allergic rhinitis and urticaria. Research consistently shows that cetirizine is effective, well tolerated, and suitable for long-term use in most patients — with no evidence of tolerance developing over time.

How Should You Use Piriteze One A Day Tablets?

Using Piriteze One A Day Tablets correctly is straightforward, but it is worth following these steps to get the most from your treatment. Always read the patient information leaflet supplied with the pack before you start.

If you are giving this medicine to a child aged 6–11, check the dosage table below carefully and use a scored tablet or an age-appropriate liquid formulation where a half-dose is required.

What Is the Correct Dose of Piriteze One A Day Tablets?

The correct dose depends on your age and kidney function. Never exceed the recommended dose, and always check with your pharmacist if you are unsure which dose applies to you.

When Is the Best Time to Use Piriteze One A Day Tablets?

You can take Piriteze One A Day Tablets at any time of day — morning, afternoon, or evening. Consistency matters more than timing. If your hay fever symptoms are worst first thing in the morning, taking your tablet the night before means it is already working when you wake up. If you notice any drowsiness after taking cetirizine, switching to an evening dose is a simple and effective adjustment.

During peak pollen season, it can be helpful to start taking your tablet a few days before you expect high pollen counts, rather than waiting until symptoms are already in full swing.

How Long Can You Use Piriteze One A Day Tablets For?

Piriteze One A Day Tablets can be used throughout the hay fever season, which typically runs from late March to September in the UK, depending on which pollens trigger your symptoms. People with year-round allergies — such as those triggered by dust mites or pet dander — may take cetirizine on a continuous basis. The NHS advises that antihistamines like cetirizine are generally safe for extended use, though it is good practice to review your treatment with a pharmacist or GP if you have been taking them for several months without reassessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Piriteze One A Day Tablets?

Using Piriteze One A Day Tablets correctly is straightforward, but it is worth following these steps to get the most from your treatment. Always read the patient information leaflet supplied with the pack before you start.

If you are giving this medicine to a child aged 6–11, check the dosage table below carefully and use a scored tablet or an age-appropriate liquid formulation where a half-dose is required.

What Is the Correct Dose of Piriteze One A Day Tablets?

The correct dose depends on your age and kidney function. Never exceed the recommended dose, and always check with your pharmacist if you are unsure which dose applies to you.

When Is the Best Time to Use Piriteze One A Day Tablets?

You can take Piriteze One A Day Tablets at any time of day — morning, afternoon, or evening. Consistency matters more than timing. If your hay fever symptoms are worst first thing in the morning, taking your tablet the night before means it is already working when you wake up. If you notice any drowsiness after taking cetirizine, switching to an evening dose is a simple and effective adjustment.

During peak pollen season, it can be helpful to start taking your tablet a few days before you expect high pollen counts, rather than waiting until symptoms are already in full swing.

How Long Can You Use Piriteze One A Day Tablets For?

Piriteze One A Day Tablets can be used throughout the hay fever season, which typically runs from late March to September in the UK, depending on which pollens trigger your symptoms. People with year-round allergies — such as those triggered by dust mites or pet dander — may take cetirizine on a continuous basis. The NHS advises that antihistamines like cetirizine are generally safe for extended use, though it is good practice to review your treatment with a pharmacist or GP if you have been taking them for several months without reassessment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Piriteze One A Day Tablets?

Most people tolerate Piriteze One A Day Tablets well, and many experience no side effects at all. However, as with any medicine, some people may notice unwanted effects. The most commonly reported side effects with cetirizine hydrochloride include:

  • Drowsiness or sedation (less common than with first-generation antihistamines, but still possible)
  • Dry mouth
  • Headache
  • Fatigue or tiredness
  • Nausea or stomach discomfort

If drowsiness is affecting you, try taking your tablet in the evening rather than the morning. Staying well hydrated throughout the day can also help ease dry mouth.

What Are the Less Common Side Effects of Piriteze One A Day Tablets?

Less commonly, some people taking cetirizine may experience the following side effects. These affect fewer than 1 in 100 people and are generally mild:

  • Dizziness or light-headedness
  • Agitation or restlessness (more likely in children)
  • Paraesthesia (tingling or pins and needles)
  • Blurred vision
  • Urinary retention (difficulty passing urine)
  • Skin rash or itching (pruritus)
  • Palpitations

If any of these persist or become bothersome, stop taking the tablets and speak to your pharmacist or GP for advice on alternative treatments.

What Are the Serious Side Effects of Piriteze One A Day Tablets?

Serious side effects from cetirizine are rare but can occur. The most significant risk is a severe allergic reaction (anaphylaxis or hypersensitivity reaction). Although uncommon, this requires immediate medical attention. Seek emergency help — call 999 or go to your nearest A&E — if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin rash, blistering, or peeling
  • Rapid or irregular heartbeat
  • Sudden drop in blood pressure causing faintness or collapse

Do not take another dose if you suspect a serious allergic reaction. Report the reaction to the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk.

What Should You Do If You Experience Side Effects of Piriteze One A Day Tablets?

For mild side effects such as drowsiness or dry mouth, simple adjustments — like changing the time of day you take the tablet or increasing your fluid intake — are often enough. If side effects are persistent, worsening, or affecting your daily life, speak to your pharmacist before stopping the medicine abruptly. They can advise whether a dose adjustment or alternative antihistamine would be more suitable for you.

Always report unexpected or severe side effects to your GP or pharmacist promptly. You can also report them directly to the MHRA via the Yellow Card scheme online.

Can Piriteze One A Day Tablets Interact With Other Medicines?

Yes — cetirizine can interact with certain medicines and substances, which may increase the risk of side effects or reduce effectiveness. The most clinically significant interactions include:

  • Alcohol: Increases sedation and impairs reaction time — avoid alcohol while taking cetirizine.
  • CNS depressants (e.g. sleeping tablets, benzodiazepines, opioids): Combined use increases drowsiness risk.
  • Ritonavir (HIV treatment): May increase cetirizine plasma levels, raising the risk of side effects.
  • Theophylline: May slightly reduce the clearance of cetirizine from the body.

Always tell your pharmacist or GP about all medicines, supplements, and herbal remedies you are currently taking before starting Piriteze One A Day Tablets.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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