Skip to product information
1 of 1

  • Images are for illustration purposes only

Chlorphenamine 4mg Hay Fever and Allergy Relief - 28 Tablets

Chlorphenamine 4mg Hay Fever and Allergy Relief - 28 Tablets

  • 1. Ozempic®️-equivalent therapy now available for weight management
  • 2. Average weight loss of 17%, with 1 in 3 patients achieving over 20%
  • 3. May help reduce osteoarthritis-related pain
  • 4. Wegovy®️ is not expected to impact the effectiveness of oral contraceptives
  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Relieves hay fever, hives, and allergic skin reactions effectively
  • ✔️ Works within 30 minutes to reduce sneezing, itching, and runny nose
  • ✔️ Suitable for adults and children aged 6 and over
  • ✔️ Sedating formula helps relieve allergy symptoms disrupting sleep
  • ✔️ 28-tablet pack provides flexible, as-needed allergy relief

Price Checker

Regular price £3.49
Sale price £3.49
Sale Sold out
  • Lowest price guarantee
  • Includes FREE private prescription
View full details

 

What Are Chlorphenamine 4mg Tablets Used For?

 

If sneezing fits, itchy eyes, and a constantly runny nose are making your day miserable, you are not alone. Hay fever affects around one in five people in the UK, and allergic reactions can strike at any time of year. Chlorphenamine 4mg tablets are a well-established, clinically proven antihistamine that helps bring fast relief from these symptoms. Available over the counter without a prescription, this 28-tablet pack from Allergy & Hayfever Chlorphenamine is an accessible, affordable option at just £3.49. You can browse the full range of treatments in our allergy and hay fever collection if you want to compare your options.

Chlorphenamine maleate has been used in the UK for decades and remains on the NHS list of recommended antihistamines for allergic conditions. It works quickly — typically within 30 minutes — making it particularly useful when symptoms flare unexpectedly.

 

How Do Chlorphenamine 4mg Tablets Work?

 

When your body encounters an allergen — pollen, pet dander, dust mites, or certain foods — it releases a chemical called histamine. Histamine binds to receptors throughout the body and triggers the familiar symptoms of an allergic reaction. Chlorphenamine works by competitively blocking these H1 histamine receptors, preventing histamine from binding and reducing the allergic response.

  • Blocks H1 histamine receptors in the body
  • Reduces inflammation in the nasal passages and airways
  • Relieves itching by acting on peripheral histamine receptors in the skin
  • Crosses the blood-brain barrier, which is why it can cause drowsiness in some people

Because it is a first-generation antihistamine, chlorphenamine acts relatively quickly but is more likely to cause sedation than newer, non-drowsy alternatives. This sedative effect can actually be useful if your symptoms are disrupting your sleep.

 

Who Should Use Chlorphenamine 4mg Tablets?

 

These tablets are suitable for adults and children aged 6 and over who are experiencing symptoms of allergic conditions. They are particularly helpful for people who need fast-acting relief or who find that symptoms are worse at night. That said, they are not right for everyone — always read the patient information leaflet carefully before use.

  • Adults and children aged 6 and over with hay fever or allergic rhinitis
  • People experiencing urticaria (hives) or skin rashes caused by allergies
  • Those with insect bite reactions or contact dermatitis
  • Individuals who need relief from itching associated with chickenpox (under medical guidance)

 

How Do Chlorphenamine Tablets Compare to Non-Drowsy Antihistamines?

 

Feature Chlorphenamine 4mg Tablets Loratadine 10mg (Non-Drowsy)
Generation First-generation antihistamine Second-generation antihistamine
Drowsiness risk Yes — common side effect Low — generally non-sedating
Onset of action Within 30 minutes Within 1–3 hours
Dosing frequency Every 4–6 hours (up to 6 tablets/day) Once daily
Suitable for night-time use Yes — sedative effect may help sleep Less suitable if sleep disruption is a concern
OTC availability Yes Yes

 

How Should You Store Chlorphenamine 4mg Tablets?

 

Store your chlorphenamine 4mg tablets below 25°C in a dry place, away from direct sunlight and moisture. Keep them in their original packaging and out of the reach and sight of children. Do not use the tablets after the expiry date printed on the pack — if in doubt, return them to your local pharmacy for safe disposal.

If you are managing multiple allergy symptoms — for example, both nasal and eye-related reactions — you might also want to explore our eye care collection for additional relief options. This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Chlorphenamine 4mg Hay Fever and Allergy Relief - 28 Tablets specifications
Treatment category Allergy and hay fever relief
Mechanism of action H1 histamine receptor antagonist
Effective for Hay fever, allergic rhinitis, urticaria, insect bites, skin rashes
Suitable for Adults and children aged 6 and over
Active ingredient Chlorphenamine maleate 4mg
Pack size 28 tablets
Strength 4mg
UK classification General Sale List (GSL)
Drug class First-generation antihistamine
Preparation Tablet
Route of administration Oral

Specifications of Chlorphenamine 4mg Hay Fever and Allergy Relief - 28 Tablets

 

What Is Chlorphenamine 4mg and What Is It Used For?

 

Chlorphenamine 4mg tablets contain the active ingredient chlorphenamine maleate, a first-generation antihistamine licensed for use in the UK. They are used to relieve the symptoms of a range of allergic conditions, including hay fever (seasonal allergic rhinitis), perennial allergic rhinitis, urticaria (hives), angioedema, food allergies, drug reactions, and itching caused by insect bites or chickenpox. The NHS recognises chlorphenamine as one of the antihistamines suitable for managing these conditions, particularly when a sedating effect is acceptable or desirable.

These tablets are available over the counter and do not require a prescription for adults and children aged 6 and over. They are not a cure for allergies but provide effective symptomatic relief while the allergen exposure continues.

 

What Do You Need to Know Before Using Chlorphenamine 4mg Tablets?

 

Before taking these tablets, it is important to check whether they are suitable for you. Do not take chlorphenamine if any of the following apply:

  • You are allergic to chlorphenamine maleate or any other ingredient in the tablet
  • You are taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days
  • You have acute asthma or a lower respiratory tract infection
  • You have narrow-angle glaucoma
  • You have an enlarged prostate or difficulty passing urine
  • You have epilepsy or a history of seizures
  • Your child is under 6 years of age
  • You are pregnant or breastfeeding (seek medical advice first)

The following medicines may interact with chlorphenamine — tell your doctor or pharmacist if you are taking any of these:

  • Other antihistamines (risk of additive sedation)
  • Sedatives, sleeping tablets, or anxiolytics
  • Tricyclic antidepressants (e.g. amitriptyline)
  • Alcohol — significantly increases drowsiness
  • Anticholinergic medicines (e.g. some bladder or stomach medicines)
  • Phenytoin (levels may be increased)

 

How Should You Use Chlorphenamine 4mg Tablets?

 

Always take chlorphenamine exactly as directed on the label or as advised by your pharmacist. Do not exceed the maximum daily dose. Swallow the tablet whole with a glass of water — it can be taken with or without food.

  1. Read the patient information leaflet fully before taking your first dose
  2. Take one tablet (4mg) by mouth with a glass of water
  3. Repeat every 4–6 hours if symptoms continue
  4. Do not take more than 6 tablets (24mg) in any 24-hour period for adults
  5. For children, follow the age-appropriate dose in the table below
  6. If symptoms persist beyond 7 days, consult your GP or pharmacist
Age Group Dose Frequency Maximum Daily Dose
Adults and children 12+ 4mg (1 tablet) Every 4–6 hours 24mg (6 tablets)
Children 6–11 years 2mg (half a tablet) Every 4–6 hours 12mg (3 tablets)
Children under 6 Not recommended — seek medical advice

If you are also dealing with cold or flu symptoms alongside your allergy, you may find it helpful to explore our cold and flu collection for complementary treatments.

 

What Are the Possible Side Effects of Chlorphenamine 4mg Tablets?

 

Like all medicines, chlorphenamine can cause side effects, although not everyone experiences them. Knowing what to look out for helps you manage them safely.

Common side effects (may affect more than 1 in 10 people):

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Headache
  • Dizziness
  • Impaired coordination

Less common side effects (may affect fewer than 1 in 10 people):

  • Blurred vision
  • Difficulty passing urine (urinary retention)
  • Nausea or stomach upset
  • Palpitations
  • Paradoxical excitability (particularly in children)
  • Skin rashes or photosensitivity

Stop taking the tablets and seek immediate medical attention if you develop signs of a serious allergic reaction, such as swelling of the face, lips, or throat, difficulty breathing, or a severe skin rash.

 

How Should You Store Chlorphenamine 4mg Tablets?

 

  • Store below 25°C in a dry place away from direct heat and sunlight
  • Keep in the original blister packaging until use
  • Keep out of the reach and sight of children at all times
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

For those managing a range of allergy-related symptoms, our ear, nose and throat collection includes additional products that may help with nasal congestion and related discomfort.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy chlorphenamine 4mg tablets online in the UK?

You can buy chlorphenamine 4mg tablets online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £3.49 for 28 tablets. They are available over the counter without a prescription for adults and children aged 6 and over. Browse our full allergy and hay fever collection for more options.

How do chlorphenamine 4mg tablets work in the body?

Chlorphenamine is a first-generation antihistamine that works by blocking H1 histamine receptors, which are activated when your body encounters an allergen. By blocking these receptors, it prevents histamine from triggering symptoms such as sneezing, itching, runny nose, and watery eyes. It begins to work within approximately 30 minutes of taking a dose.

How do I take chlorphenamine 4mg tablets step by step?

Adults and children aged 12 and over should take one 4mg tablet with a glass of water every four to six hours as needed. Do not take more than six tablets in any 24-hour period. For children aged 6 to 11, the dose is half a tablet (2mg) every four to six hours — always follow the patient information leaflet.

What is the best time of day to take chlorphenamine 4mg tablets?

Chlorphenamine can be taken at any time when symptoms occur, but because it commonly causes drowsiness, many people find it most convenient to take it in the evening or before bed. If you need to take it during the day, avoid driving, cycling, or operating machinery until you know how it affects you. Taking it with food may help reduce any stomach upset.

How do I manage the drowsiness side effect of chlorphenamine?

Drowsiness is the most common side effect of chlorphenamine and is more likely at higher doses. To manage it, avoid alcohol, avoid driving or operating heavy machinery, and consider taking your dose in the evening if daytime sedation is a problem. If drowsiness is significantly affecting your daily life, speak to your pharmacist about switching to a non-drowsy antihistamine such as loratadine or cetirizine.

Who is eligible to take chlorphenamine 4mg tablets?

Chlorphenamine 4mg tablets are suitable for adults and children aged 6 and over who are experiencing symptoms of hay fever, allergic rhinitis, urticaria, insect bites, or other allergic reactions. They are not suitable for children under 6, people taking MAOIs, or those with certain conditions such as glaucoma, an enlarged prostate, or epilepsy. Always read the full patient information leaflet before use.

What happens if I miss a dose of chlorphenamine 4mg?

If you miss a dose, take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case skip the missed dose entirely. Never take a double dose to compensate for a missed one, as this increases the risk of side effects. Chlorphenamine is taken as needed for symptom relief, so missing an occasional dose is unlikely to cause problems.

Can I take chlorphenamine 4mg tablets during pregnancy?

Chlorphenamine is not recommended during pregnancy unless advised by a doctor, as there is limited safety data available. If you are pregnant and suffering from hay fever or allergic symptoms, speak to your GP or midwife before taking any antihistamine. They can advise on the safest option for your individual circumstances.

How does chlorphenamine compare to loratadine for hay fever?

Chlorphenamine is a first-generation antihistamine that acts quickly but commonly causes drowsiness, whereas loratadine is a second-generation, non-drowsy antihistamine taken once daily. Both are effective at relieving hay fever symptoms, but loratadine is generally preferred for daytime use. Chlorphenamine may be more suitable if you need faster relief or if symptoms are disrupting your sleep.

How long can you take chlorphenamine 4mg tablets for?

Chlorphenamine can be taken for short-term relief of allergy symptoms, typically for the duration of allergen exposure such as the hay fever season. If your symptoms persist beyond seven days without improvement, or if you find yourself needing it continuously for longer periods, speak to your GP or pharmacist. Long-term use should be reviewed by a healthcare professional.

Can chlorphenamine 4mg tablets be taken with other medicines?

Chlorphenamine can interact with several medicines, including MAOIs, tricyclic antidepressants, sedatives, sleeping tablets, and other antihistamines. Alcohol also significantly increases the sedative effect. Always tell your pharmacist or GP about all medicines, supplements, and herbal remedies you are taking before starting chlorphenamine.

Is chlorphenamine 4mg suitable for children with hay fever?

Yes, chlorphenamine 4mg tablets can be used in children aged 6 and over, with the dose adjusted according to age — children aged 6 to 11 should take half a tablet (2mg) every four to six hours. It is not suitable for children under 6 years of age. If you are unsure about giving antihistamines to your child, speak to your pharmacist or GP first.

What are the alternatives to chlorphenamine 4mg tablets for allergy relief?

Alternatives include non-drowsy second-generation antihistamines such as loratadine, cetirizine, and fexofenadine, which are taken once daily and less likely to cause sedation. Nasal corticosteroid sprays such as beclometasone are also effective for hay fever. You can explore a range of options in our allergy and hay fever collection.

Can chlorphenamine cause a paradoxical reaction in children?

Yes, in some children chlorphenamine can cause a paradoxical excitatory reaction — meaning instead of becoming drowsy, the child becomes hyperactive, irritable, or restless. This is a known but less common side effect of first-generation antihistamines. If this occurs, stop the medication and speak to your GP or pharmacist about a suitable alternative.

What does the latest research say about chlorphenamine for allergy relief?

Chlorphenamine remains a well-evidenced, widely used antihistamine that has been in clinical use for over 70 years. Current NHS and NICE guidance acknowledges its effectiveness for allergic conditions while noting that second-generation antihistamines are generally preferred for daytime use due to their lower sedation risk. It continues to be recommended for specific situations where its sedative properties are clinically useful, such as night-time symptom relief or itch management.

How Should You Use Chlorphenamine 4mg Tablets?

Chlorphenamine 4mg tablets are taken by mouth with a glass of water. They can be taken with or without food, though taking them with food may help if you experience any stomach discomfort. Always read the patient information leaflet before starting treatment and follow the dosage instructions carefully.

Follow these steps each time you take a dose:

What Is the Correct Dose of Chlorphenamine 4mg Tablets?

The correct dose depends on your age. Always use the lowest effective dose and do not exceed the maximum daily amount. If you are unsure about the right dose for your child, speak to your pharmacist before administering.

When Is the Best Time to Use Chlorphenamine 4mg Tablets?

Because chlorphenamine commonly causes drowsiness, many people find it most practical to take their dose in the evening or at bedtime. This way, the sedative effect works in your favour rather than interfering with your daily activities. If you need to take it during the day — for example, during a sudden allergic reaction — avoid driving, cycling, or operating machinery until you are confident it is not affecting your alertness.

During hay fever season, some people take a dose before going outdoors or before anticipated allergen exposure to help prevent symptoms from developing. Speak to your pharmacist if you are unsure about the best timing for your situation.

How Long Can You Use Chlorphenamine 4mg Tablets For?

Chlorphenamine 4mg tablets are intended for short-term symptomatic relief. Most people use them for the duration of their allergen exposure — for example, throughout the hay fever season or until a skin reaction resolves. If your symptoms have not improved after seven days of use, or if they worsen at any point, stop taking the tablets and consult your GP or pharmacist.

Long-term, continuous use of chlorphenamine is not generally recommended without medical supervision, as tolerance and ongoing side effects may become a concern. Your pharmacist can advise on whether a different antihistamine or a longer-term management plan would be more appropriate for your needs.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)

What Are the Most Common Side Effects of Chlorphenamine 4mg Tablets?

The most frequently reported side effect of chlorphenamine is drowsiness or sedation. This occurs because, as a first-generation antihistamine, chlorphenamine crosses the blood-brain barrier and has a sedating effect on the central nervous system. While this can be inconvenient during the day, it may actually be helpful if your allergy symptoms are disrupting your sleep at night.

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Headache
  • Dizziness
  • Impaired coordination or concentration

What Are the Less Common Side Effects of Chlorphenamine 4mg Tablets?

Some people experience side effects that are less frequent but still worth being aware of. These tend to be related to the anticholinergic properties of chlorphenamine, which affect various body systems beyond the immune response.

  • Blurred vision
  • Difficulty passing urine (urinary retention)
  • Nausea or stomach upset
  • Palpitations or increased heart rate
  • Paradoxical excitability, restlessness, or irritability (more common in children)
  • Skin sensitivity to sunlight (photosensitivity)
  • Tremor

What Are the Serious Side Effects of Chlorphenamine 4mg Tablets?

Serious side effects are rare but require immediate medical attention. Stop taking chlorphenamine and seek emergency help if you experience any of the following, as they may indicate a severe allergic reaction (anaphylaxis) or another serious adverse event.

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin rash, blistering, or peeling
  • Seizures or convulsions
  • Severe dizziness or loss of consciousness

What Should You Do If You Experience Side Effects of Chlorphenamine?

If you experience mild side effects such as drowsiness or dry mouth, these often improve as your body adjusts to the medicine. Staying well hydrated, avoiding alcohol, and taking your dose in the evening can all help reduce the impact of common side effects. If side effects are persistent or troublesome, speak to your pharmacist — they may recommend switching to a non-drowsy antihistamine.

For any serious or unexpected side effects, stop taking the tablets immediately and contact your GP, call NHS 111, or in an emergency dial 999. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Chlorphenamine 4mg Tablets Interact With Other Medicines?

Yes. Chlorphenamine has several clinically significant interactions that you should be aware of before starting treatment. Taking it alongside other medicines that cause sedation — such as sleeping tablets, anxiolytics, opioid painkillers, or other antihistamines — can significantly increase drowsiness and impair your ability to function safely. Alcohol has a similar additive effect and should be avoided.

Chlorphenamine must not be taken within 14 days of stopping a monoamine oxidase inhibitor (MAOI), as this combination can cause dangerous interactions. Tricyclic antidepressants may also enhance the anticholinergic effects of chlorphenamine. Always inform your pharmacist or GP of all medicines, supplements, and herbal products you are currently taking before starting chlorphenamine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

We’re a safe and
regulated UK service

Registered Pharmacy Badge

Lowest Price Guarantee

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

100% discreet packaging

We're convinced you won't find your treatment cheaper, but if you do we'll refund the difference.

Find out more

Agent

Need help?
Talk to our friendly experts now

How our service works

Service Setup

Service setup

Discreet Packaging

Discreet packaging

Express Delivery

Express delivery