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Difflam Spray

Difflam Spray

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Difflam Spray for Mouth and Throat Pain Relief

 

You can use this topical anti-inflammatory medicine to treat painful conditions affecting your mouth and throat. The active ingredient benzydamine hydrochloride works locally at the site of application to reduce inflammation and provide pain relief. This makes it particularly effective for conditions such as mouth ulcers, sore throats, and dental pain.

The spray format allows you to target the affected area directly, delivering the medicine precisely where you need it most. Each spray delivers a measured dose, making it easy to control how much medicine you apply.

 

How Benzydamine Hydrochloride Works in Your Mouth

 

Benzydamine hydrochloride belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). When you spray it onto the affected area, it penetrates the tissues and blocks the production of substances that cause pain and inflammation.

Unlike systemic pain relief medicines that work throughout your body, this medicine acts locally where you apply it. This targeted approach means you can achieve effective pain relief with minimal absorption into your bloodstream, reducing the risk of systemic side effects.

 

Who Can Benefit from This Throat and Mouth Treatment

 

This medicine is suitable for adults and children over 6 years of age who experience painful inflammatory conditions of the mouth and throat. You might find it particularly helpful if you suffer from recurrent mouth ulcers or need relief from dental procedures.

The following conditions commonly respond well to treatment:

  • Mouth ulcers and aphthous stomatitis
  • Sore throat and pharyngitis
  • Pain following dental procedures
  • Gingivitis and gum inflammation

If you're looking for additional support during cold and flu season, you might also consider browsing our cold and flu collection for complementary treatments.

 

Why Choose a Preservative-Free Formula

 

This difflam spray formulation is designed to minimise irritation in your already sensitive mouth and throat tissues. The absence of certain preservatives reduces the likelihood of additional irritation or allergic reactions, which is particularly important when treating inflamed areas.

The spray mechanism also helps maintain the sterility of the remaining solution without relying heavily on preservatives, as each application is delivered without contaminating the contents of the bottle.

 

Clinical Suitability and Storage Requirements

 

You should store this medicine at room temperature, away from direct sunlight and heat sources. Keep the bottle upright and ensure the spray mechanism is clean after each use to maintain hygiene and proper function.

The medicine is suitable for short-term use, typically for periods of up to 7 days unless your doctor or pharmacist advises otherwise. If your symptoms persist or worsen during treatment, you should seek medical advice promptly.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

 

Proper Application Technique for Mouth and Throat Spraying

You should shake the bottle gently before each use to ensure the medicine is properly mixed. Remove the cap and hold the bottle upright, pointing the spray nozzle towards the affected area in your mouth or throat. Press down firmly on the pump to release the spray, aiming directly at the painful area.

For mouth ulcers or gum problems, direct the spray onto the specific affected area. For throat pain, aim towards the back of your throat while breathing normally. You should avoid inhaling deeply during application to prevent the medicine from going into your lungs.

Recommended Dosage and Treatment Duration

Adults and children over 12 years can typically use 4-8 sprays every 1.5 to 3 hours as needed. Children aged 6-12 years should use 4 sprays every 1.5 to 3 hours. You should not exceed the recommended number of applications per day as stated on the product packaging.

Treatment duration should generally not exceed 7 days unless advised by a healthcare professional. If your symptoms do not improve within this time or if they worsen, you should consult your doctor or pharmacist for further advice. You should wait at least 30 minutes after application before eating or drinking to allow the medicine to work effectively.

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Understanding Potential Side Effects of Benzydamine Treatment

Like all medicines, Difflam Spray can have side effects, although not everyone will experience them. Most people tolerate this medicine well when used as directed, particularly because it acts locally rather than throughout your entire body.

The most commonly reported side effects include temporary numbness or tingling in your mouth, mild burning sensation upon application, and altered taste perception. These effects are usually mild and temporary, resolving shortly after application. For comprehensive oral care support, you may wish to explore our oral health range for additional products.

Known side effects that may occur include:

  • Temporary numbness of the mouth or tongue
  • Mild burning or stinging sensation
  • Altered taste or metallic taste
  • Dry mouth
  • Throat irritation
  • Nausea in sensitive individuals
  • Local allergic reactions such as rash
  • Swelling of treated area
  • Increased salivation
  • Headache
  • Dizziness
  • Skin sensitivity reactions

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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