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Daktarin (Miconazole) Oral Gel - 15g

Daktarin (Miconazole) Oral Gel - 15g

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  • ✔️ Treats oral thrush caused by Candida fungal overgrowth
  • ✔️ Suitable for adults and infants over four months old
  • ✔️ Gel formulation maximises contact with infected mouth tissue
  • ✔️ Effective against Candida albicans and gram-positive bacteria
  • ✔️ Clinically established antifungal treatment available without prescription

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What Is Miconazole Oral Gel and How Does It Treat Mouth Infections?

 

Oral thrush is more common than many people realise. It can affect anyone — from newborns to older adults — and it tends to appear at the most inconvenient times. Miconazole oral gel, sold under the well-known brand name Daktarin, is a clinically established antifungal treatment that targets the root cause of these infections directly inside the mouth. Each gram of gel contains 20mg of miconazole, giving you a targeted dose right where it's needed. You can browse our full range of athlete's foot and fungal infection treatments if you're dealing with fungal problems elsewhere on the body too.

Oral thrush is caused by an overgrowth of Candida fungi — most often Candida albicans — in the mouth and throat. It typically presents as creamy white patches on the tongue, inner cheeks, or roof of the mouth, sometimes accompanied by soreness or a burning sensation. The NHS confirms that oral thrush is particularly common in babies, people who wear dentures, and those with weakened immune systems. Daktarin Oral Gel 15g is available over the counter, making it straightforward to access without needing a GP appointment in most cases.

 

How Does Daktarin Oral Gel Work Against Fungal Infections?

 

Miconazole belongs to the azole class of antifungal medicines. It works by interfering with the production of ergosterol, a key component of the fungal cell membrane. Without ergosterol, the membrane becomes unstable and leaky, ultimately killing the fungal cells. It also has some antibacterial activity against gram-positive bacteria, which can be a useful bonus when mixed infections are present.

  • Miconazole inhibits the enzyme lanosterol 14-alpha-demethylase, blocking ergosterol synthesis
  • The fungal cell membrane loses integrity and the cell contents leak out
  • Candida cells are unable to replicate and die off
  • The gel formulation keeps the active ingredient in contact with infected tissue for longer

 

Who Should Use Daktarin Oral Gel and Is It Right for You?

 

This gel is suitable for a wide range of people dealing with fungal infections of the mouth and throat. It can be used in adults, children, and infants over 4 months of age, though the application method differs slightly depending on age. It's particularly useful for people who wear dentures, as the gel can be applied directly to the denture surface as well as the mouth.

  • Adults and older children with oral thrush (white patches, soreness, or burning in the mouth)
  • Infants aged 4 months and over with oral thrush (under medical supervision)
  • Denture wearers experiencing fungal infections beneath the denture plate
  • People with angular cheilitis (cracked corners of the mouth) caused by Candida

 

How Does Daktarin Oral Gel Compare to Nystatin Oral Suspension?

 

Feature Daktarin Oral Gel (Miconazole) Nystatin Oral Suspension
Active ingredient Miconazole 20mg/g Nystatin 100,000 units/ml
Suitable age 4 months and over All ages including newborns
OTC availability Yes (15g pack) Prescription only in UK
Application method Gel applied to mouth with finger or spoon Liquid dropped into mouth

 

How Should You Store Daktarin Oral Gel and Is It Suitable Long-Term?

 

Store Daktarin Oral Gel below 25°C and do not refrigerate. Keep the tube tightly closed when not in use and store it out of the sight and reach of children. The gel should not be used after the expiry date printed on the tube and carton. If you're managing recurring oral thrush, it's worth speaking to your GP or pharmacist, as frequent episodes may indicate an underlying condition that needs investigation. You might also find it helpful to explore our oral health collection for complementary products to support mouth hygiene during treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Daktarin (Miconazole) Oral Gel 15g specifications
Treatment category Antifungal / Oral thrush
Mechanism of action Inhibits ergosterol synthesis in fungal cell membranes
Effective against Candida species (including Candida albicans), gram-positive bacteria
Suitable for Adults, children, and infants over 4 months
Active ingredient Miconazole 20mg/g
Pack size 15g tube
Strength 20mg/g (2% w/w)
UK classification General Sale List (GSL) / Pharmacy (P) medicine
Drug class Azole antifungal
Preparation Oral gel
Route of administration Oral (topical application inside the mouth)

Specifications of Daktarin (Miconazole) Oral Gel 15g

 

What Is Daktarin Oral Gel and What Is It Used For?

 

Daktarin Oral Gel contains miconazole at a concentration of 20mg per gram of gel. It is used to treat fungal infections of the mouth and throat — most commonly oral thrush (oropharyngeal candidiasis) — as well as fungal infections affecting the gums and the area beneath dentures. The NHS describes oral thrush as a condition where the Candida fungus grows out of control inside the mouth, causing white patches, redness, and soreness. Miconazole oral gel works locally inside the mouth, with only a small amount absorbed into the bloodstream, making it generally well tolerated.

 

What Do You Need to Know Before Using Daktarin Oral Gel?

 

Before using this gel, it's important to check whether it is appropriate for you. There are certain situations where you should not use it, and others where extra caution is needed.

Do not use Daktarin Oral Gel if you:

  • Are allergic to miconazole or any other ingredient in the gel
  • Have liver problems
  • Are in the first trimester of pregnancy
  • Are caring for an infant under 4 months of age
  • Are taking medicines that interact with miconazole (see below)

Known drug interactions — tell your pharmacist if you are taking:

  • Warfarin or other anticoagulants (miconazole can significantly increase bleeding risk)
  • Oral hypoglycaemic medicines such as sulphonylureas (risk of low blood sugar)
  • Phenytoin (risk of increased phenytoin levels)
  • Ciclosporin (risk of increased ciclosporin toxicity)
  • Statins such as simvastatin (risk of muscle problems)

The interaction with warfarin is particularly important. Even small amounts of miconazole absorbed from the gel can enhance the anticoagulant effect of warfarin, potentially causing serious bleeding. Always inform your pharmacist if you are on any regular medicines before purchasing this product.

 

How Should You Use Daktarin Oral Gel?

 

Using the gel correctly makes a real difference to how quickly it works. The key is to keep it in contact with the infected tissue for as long as possible — so apply it after meals rather than before, and try not to eat or drink immediately afterwards.

  1. Wash your hands thoroughly before applying the gel
  2. Use a clean spoon or your finger to measure out the correct dose
  3. Apply the gel directly to the affected areas inside the mouth
  4. Hold the gel in your mouth for as long as you comfortably can before swallowing
  5. Apply four times daily (after meals and at bedtime) for adults
  6. Continue treatment for at least 7 days and for 2 days after symptoms have resolved
  7. If treating denture-related thrush, also apply the gel to the denture surface
Indication Age Group Dose Frequency
Oral thrush Adults and children over 6 years 2.5ml (approx. half a teaspoon) Four times daily
Oral thrush Children under 6 years 1.25ml (approx. quarter teaspoon) Four times daily
Oral thrush Infants 4 months and over Small amount applied to each side of mouth Four times daily (after feeds)

If you are treating a breastfed baby, it is important that the mother's nipples are also treated to prevent reinfection. You may find it helpful to explore our baby and toddler health range for additional support products during this time.

 

What Are the Possible Side Effects of Daktarin Oral Gel?

 

Like all medicines, Daktarin Oral Gel can cause side effects, although not everyone experiences them. Most side effects are mild and resolve on their own.

Common side effects:

  • Nausea
  • Vomiting
  • Dry mouth
  • Mild irritation or burning sensation in the mouth

Less common side effects:

  • Diarrhoea
  • Taste disturbances
  • Skin rash or itching
  • Allergic reactions (including swelling of the face, lips, or throat — seek urgent medical help if this occurs)

If you notice any side effects not listed here, or if existing side effects worsen, stop using the gel and speak to your pharmacist or GP. Serious allergic reactions are rare but require immediate medical attention.

 

How Should You Store Daktarin Oral Gel?

 

Correct storage helps maintain the gel's effectiveness throughout the course of treatment. For a wider range of treatments to support your health, take a look at our thrush treatments collection.

  • Store below 25°C — do not refrigerate
  • Keep the tube tightly closed after each use
  • Store out of the sight and reach of children
  • Do not use after the expiry date printed on the tube and carton
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy miconazole oral gel online in the UK?

You can buy Daktarin Miconazole Oral Gel 15g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription for adults and children over 4 months of age. Simply add it to your basket and it will be dispatched promptly to your door.

How does miconazole oral gel work in the body?

Miconazole works by blocking the production of ergosterol, a vital component of the fungal cell membrane. Without ergosterol, the membrane breaks down and the Candida cells die. The gel formulation keeps the active ingredient in direct contact with the infected tissue inside the mouth, maximising its local effect.

How do I use Daktarin Oral Gel step by step?

Apply the correct dose of gel to the affected areas inside your mouth using a clean finger or spoon after meals. Hold the gel in your mouth for as long as possible before swallowing, and avoid eating or drinking immediately afterwards. Repeat four times daily — after each meal and at bedtime — for at least 7 days.

How long does it take for Daktarin Oral Gel to work?

Most people notice an improvement in symptoms within 2 to 3 days of starting treatment. However, it is essential to continue using the gel for the full course — at least 7 days and for 2 days after symptoms have cleared — to prevent the infection from returning. Stopping too early is one of the most common reasons oral thrush comes back.

What is the correct dose of miconazole oral gel for adults?

The standard adult dose is approximately 2.5ml (roughly half a teaspoon) applied four times daily — after each meal and at bedtime. Do not exceed this dose unless directed by a healthcare professional. If your symptoms have not improved after 7 days, speak to your GP or pharmacist.

What are the side effects of Daktarin Oral Gel and how do I manage them?

The most common side effects include nausea, vomiting, and mild irritation inside the mouth. These are usually mild and tend to settle as your body adjusts to the treatment. If you experience swelling of the face or throat, difficulty breathing, or a severe rash, stop using the gel immediately and seek urgent medical attention, as these may indicate a rare allergic reaction.

Is Daktarin Oral Gel safe for babies and young children?

Daktarin Oral Gel is not recommended for infants under 4 months of age due to the risk of choking. For babies aged 4 months and over, it can be used carefully under medical supervision — apply a small amount to each side of the mouth after feeds rather than placing it at the back of the throat. Always consult your GP or health visitor before treating a young baby for oral thrush.

Who is eligible to use Daktarin Oral Gel without a prescription?

Adults and children over 4 months of age with oral thrush can use Daktarin Oral Gel without a prescription in most cases. However, it is not suitable for people with liver problems, those in the first trimester of pregnancy, or those taking certain medicines such as warfarin. If you are unsure whether it is right for you, speak to a pharmacist before purchasing.

Can I use Daktarin Oral Gel if I am pregnant or breastfeeding?

Miconazole oral gel is generally avoided during the first trimester of pregnancy, and caution is advised throughout pregnancy due to some systemic absorption. If you are breastfeeding and your baby has oral thrush, the gel can be used for the baby, but you should also treat your nipples to prevent reinfection passing back and forth. Always seek advice from your GP or midwife before using any medicine during pregnancy or breastfeeding.

What happens if I miss a dose of Daktarin Oral Gel?

If you miss a dose, apply it as soon as you remember — unless it is nearly time for your next dose, in which case simply skip the missed one and carry on as normal. Do not apply a double dose to make up for a missed one. Consistency is important with antifungal treatment, so try to apply the gel at regular intervals throughout the day.

Can Daktarin Oral Gel interact with warfarin?

Yes — this is one of the most clinically significant interactions to be aware of. Even the small amount of miconazole absorbed from the oral gel can substantially increase the anticoagulant effect of warfarin, raising the risk of serious bleeding. If you are taking warfarin or any other anticoagulant, do not use this gel without first speaking to your GP or anticoagulation clinic.

What are the alternatives to Daktarin Oral Gel for oral thrush?

The main alternative for oral thrush is nystatin oral suspension, which is available on prescription and is suitable for all ages including newborns. For adults with persistent or recurrent oral thrush, a GP may prescribe fluconazole capsules as a single-dose or short-course treatment. You can explore our fungal infection treatments for other antifungal options available without a prescription.

How long can you use Daktarin Oral Gel for?

The standard course of treatment is 7 to 14 days, continuing for 2 days after symptoms have resolved. You should not use the gel for longer than recommended without medical advice. If your symptoms persist beyond 2 weeks or keep coming back, see your GP, as recurrent oral thrush can sometimes indicate an underlying health condition such as diabetes or a weakened immune system.

Can I use Daktarin Oral Gel on my dentures?

Yes — if your oral thrush is related to wearing dentures, you should apply the gel both inside your mouth and directly to the denture surface. Remove your dentures at night and soak them in an appropriate denture cleanser. Good denture hygiene is an important part of preventing fungal infections from recurring, so maintaining a regular cleaning routine alongside treatment is strongly recommended.

What does the latest research say about miconazole oral gel for oral thrush?

Miconazole has been used clinically for decades and remains a first-line treatment for oropharyngeal candidiasis in many guidelines. Published clinical evidence consistently supports its efficacy against Candida albicans, and it continues to be recommended by the NHS for oral thrush in adults and children. For broader oral health support alongside your treatment, visit our oral health collection.

How Should You Use Daktarin Oral Gel?

Using Daktarin Oral Gel correctly is straightforward, but the technique matters. The gel needs to stay in contact with the infected tissue for as long as possible to work effectively, so always apply it after eating rather than before. Wash your hands before and after application.

What Is the Correct Dose of Daktarin Oral Gel?

The dose varies depending on age. Always follow the dosage instructions on the packaging or as directed by your pharmacist. Do not give more than the recommended amount, particularly to young children.

When Is the Best Time to Use Daktarin Oral Gel?

The best time to apply the gel is after meals and at bedtime. Applying it after eating means there is less saliva in the mouth to wash the gel away, allowing it to remain in contact with the infected tissue for longer. The bedtime dose is particularly useful as there is less swallowing during sleep, giving the gel more time to work overnight.

For infants, apply the gel after feeds rather than before, and take care to place it on the sides of the mouth rather than at the back of the throat to avoid any risk of choking.

How Long Can You Use Daktarin Oral Gel For?

The recommended treatment duration is at least 7 days, continuing for 2 days after symptoms have fully resolved. This helps ensure the infection is completely cleared and reduces the risk of it returning. Most people complete a course of 7 to 14 days in total.

If your symptoms have not improved after 7 days of treatment, or if they return shortly after finishing the course, speak to your GP. Recurrent oral thrush may need further investigation to rule out an underlying cause. Do not use the gel for longer than recommended without medical advice.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

How Should You Use Daktarin Oral Gel?

Using Daktarin Oral Gel correctly is straightforward, but the technique matters. The gel needs to stay in contact with the infected tissue for as long as possible to work effectively, so always apply it after eating rather than before. Wash your hands before and after application.

What Is the Correct Dose of Daktarin Oral Gel?

The dose varies depending on age. Always follow the dosage instructions on the packaging or as directed by your pharmacist. Do not give more than the recommended amount, particularly to young children.

When Is the Best Time to Use Daktarin Oral Gel?

The best time to apply the gel is after meals and at bedtime. Applying it after eating means there is less saliva in the mouth to wash the gel away, allowing it to remain in contact with the infected tissue for longer. The bedtime dose is particularly useful as there is less swallowing during sleep, giving the gel more time to work overnight.

For infants, apply the gel after feeds rather than before, and take care to place it on the sides of the mouth rather than at the back of the throat to avoid any risk of choking.

How Long Can You Use Daktarin Oral Gel For?

The recommended treatment duration is at least 7 days, continuing for 2 days after symptoms have fully resolved. This helps ensure the infection is completely cleared and reduces the risk of it returning. Most people complete a course of 7 to 14 days in total.

If your symptoms have not improved after 7 days of treatment, or if they return shortly after finishing the course, speak to your GP. Recurrent oral thrush may need further investigation to rule out an underlying cause. Do not use the gel for longer than recommended without medical advice.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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Maureen Taylor

Have used before

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Medication fine, customer service very poor....

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Tracy Robson

Daktarin oral gel is brilliant, you could once buy it in a chemist.

What Are the Most Common Side Effects of Daktarin Oral Gel?

Most people tolerate Daktarin Oral Gel well, and side effects are generally mild. The most frequently reported ones relate to the digestive system, particularly when the gel is swallowed rather than held in the mouth.

  • Nausea
  • Vomiting
  • Dry mouth
  • Mild burning or irritation inside the mouth
  • Unpleasant taste or taste changes

These effects are usually short-lived and tend to improve as your body adjusts to the treatment. Applying the gel after meals rather than on an empty stomach can help reduce nausea.

What Are the Less Common Side Effects of Daktarin Oral Gel?

Less commonly, some people experience side effects that are slightly more noticeable but still generally manageable. If any of the following persist or bother you, speak to your pharmacist.

  • Diarrhoea or stomach discomfort
  • Skin rash or itching
  • Headache
  • Increased liver enzymes (detected on blood tests — relevant mainly with prolonged use)

What Are the Serious Side Effects of Daktarin Oral Gel?

Serious side effects are rare but require immediate attention. The most significant risk is a severe allergic reaction (anaphylaxis), which, though uncommon, can occur with any medicine. Signs to watch for include sudden swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, a widespread skin rash, or a sudden drop in blood pressure causing dizziness or collapse. If you experience any of these, stop using the gel immediately and call 999 or go to your nearest A&E department.

There is also a clinically important risk of increased bleeding in people taking warfarin. Even the small amount of miconazole absorbed through the mouth can significantly enhance warfarin's effect. If you are on anticoagulant therapy and notice unusual bruising or bleeding, seek medical advice promptly.

What Should You Do If You Experience Side Effects?

For mild side effects such as nausea or mouth irritation, try applying the gel after food and holding it in your mouth before swallowing slowly. This can reduce the amount reaching the stomach at once. If side effects are persistent, uncomfortable, or worsening, stop using the gel and speak to your pharmacist or GP before continuing.

You can also report suspected side effects directly to the MHRA through the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps the MHRA monitor the safety of medicines used in the UK.

Can Daktarin Oral Gel Interact With Other Medicines?

Yes — miconazole has several clinically significant drug interactions, even when used as an oral gel. Although systemic absorption is relatively low, it is enough to affect the metabolism of certain medicines processed by the liver's CYP enzymes.

  • Warfarin and anticoagulants: Significantly increased bleeding risk — avoid combination or monitor INR closely under medical supervision
  • Sulphonylureas (e.g. glibenclamide, gliclazide): Risk of hypoglycaemia (low blood sugar)
  • Phenytoin: Risk of phenytoin toxicity due to increased blood levels
  • Ciclosporin: Risk of increased ciclosporin levels and toxicity
  • Simvastatin and other statins: Risk of myopathy (muscle damage)

Always tell your pharmacist about all medicines you are taking — including over-the-counter products and supplements — before starting Daktarin Oral Gel.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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