Wegovy vs Mounjaro Results UK | Cured Pharmacy

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Wegovy vs Mounjaro - Cheapest UK Price from £124.99

Compare Wegovy vs Mounjaro weight loss results at the cheapest UK price from £124.99 plus £20 off with code Weightlossnew.

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£89.00 From £69.00 £10 discount using discount code Weightlossnew
LIVE PRICING

Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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What's The Difference Between Wegovy And Mounjaro Results?

Understanding the difference between Wegovy vs Mounjaro weight loss results UK is crucial when choosing your treatment pathway. Both medications are MHRA-licensed injectable therapies that have demonstrated significant efficacy in clinical trials, but they work through different mechanisms and produce distinct outcomes. At Cured Pharmacy, our UK-registered clinical team helps you navigate these options with transparent pricing and expert guidance.

Clinical Trial Results: Wegovy vs Mounjaro Weight Loss Outcomes

Mounjaro (tirzepatide) demonstrated superior weight loss in head-to-head comparisons with semaglutide-based treatments. In the SURPASS-2 trial, patients taking the highest dose of tirzepatide (15mg) achieved an average body weight reduction of 22.5% over 72 weeks, compared to 15.8% with semaglutide 1mg [1]. This represents a clinically meaningful difference for many patients seeking maximum efficacy.

Wegovy (semaglutide 2.4mg) remains highly effective in its own right. The STEP 1 trial showed participants lost an average of 14.9% of their initial body weight over 68 weeks, with nearly one-third achieving at least 20% weight reduction [2]. Both medications significantly outperform older weight loss treatments and lifestyle interventions alone.

It's important to note that individual results vary considerably. Your response depends on factors including baseline BMI, adherence to the dosing schedule, concurrent lifestyle modifications, and individual metabolic differences. These averages from clinical trials represent outcomes in controlled research settings with regular medical supervision.

How Mounjaro and Wegovy Work Differently

The key difference lies in their mechanism of action. Wegovy contains semaglutide, a GLP-1 (glucagon-like peptide-1) receptor agonist that mimics a single natural hormone involved in appetite regulation and blood sugar control [2]. This proven pathway has been used successfully in diabetes management for over a decade before being licensed for weight management.

Mounjaro contains tirzepatide, the first dual GIP/GLP-1 receptor agonist licensed in the UK [1]. By activating both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors simultaneously, tirzepatide engages two complementary pathways. This dual action may explain the enhanced weight loss observed in clinical trials, though researchers continue to investigate the precise mechanisms.

What This Means for Your Treatment Journey

Both medications slow gastric emptying, reduce appetite, and improve feelings of fullness after eating. Most patients report decreased food cravings and smaller portion sizes within the first few weeks of treatment. The dual-action mechanism of Mounjaro may produce slightly faster initial weight loss in some individuals, though both require gradual dose escalation to minimise side effects.

Wegovy vs Mounjaro: Side Effects and Tolerability

Both medications share a similar side effect profile, as they work on overlapping biological pathways. The most common adverse effects are gastrointestinal: nausea, diarrhoea, constipation, and occasional vomiting [1][2]. These symptoms typically occur during dose escalation and often diminish as your body adjusts to the medication.

In clinical trials, approximately 44% of Mounjaro users experienced nausea compared to 40% of Wegovy users at therapeutic doses [1][2]. Discontinuation rates due to side effects were comparable between both treatments, ranging from 4-7% depending on the dose. Your prescriber will start you on the lowest dose and increase gradually over several months to improve tolerability.

Serious adverse events are rare but require immediate medical attention. These include signs of pancreatitis (severe abdominal pain), gallbladder problems, severe allergic reactions, or changes in vision. Both medications carry a boxed warning regarding thyroid C-cell tumours observed in animal studies, though no causal relationship has been established in humans [3].

Managing Common Side Effects

Our clinical team at Cured Pharmacy provides comprehensive guidance on minimising gastrointestinal symptoms. Strategies include eating smaller meals, avoiding high-fat foods, staying well-hydrated, and timing your injection appropriately. Most patients find side effects manageable and consider them acceptable given the significant weight loss benefits achieved.

Feature Wegovy (Semaglutide) Mounjaro (Tirzepatide)
Mechanism GLP-1 receptor agonist Dual GIP/GLP-1 receptor agonist
Average Weight Loss 14.9% over 68 weeks 22.5% over 72 weeks
Dosing Frequency Once weekly injection Once weekly injection
Maintenance Dose 2.4mg weekly 10mg or 15mg weekly
Starting Price at Cured From £69.00 From £69.00
Escalation Period 5 months to maintenance 4 months to maintenance
Common Side Effects Nausea (40%), diarrhoea, constipation Nausea (44%), diarrhoea, constipation
MHRA Licensed Since 2022 (weight management) 2023 (weight management)

Dosing Schedules and Treatment Progression

Both Wegovy and Mounjaro require once-weekly subcutaneous injections, typically administered on the same day each week. The injection can be given at any time of day, with or without meals, and rotated between the abdomen, thigh, or upper arm. This convenience factor makes both treatments practical for long-term use.

Wegovy follows a five-month dose escalation: starting at 0.25mg weekly, increasing to 0.5mg, then 1mg, 1.7mg, and finally the maintenance dose of 2.4mg [2]. This gradual titration helps your body adapt and reduces the likelihood of gastrointestinal side effects. If you experience persistent symptoms at any stage, your prescriber may slow the escalation.

Mounjaro uses a similar approach with four escalation steps: 2.5mg, 5mg, 10mg, and 15mg, each maintained for at least four weeks [1]. Some patients achieve their weight loss goals at the 10mg dose and don't require further increases. Your UK prescriber will adjust your dosing based on your response, tolerability, and clinical assessment at each stage.

Cost Comparison: Wegovy vs Mounjaro UK Pricing

At Cured Pharmacy, Mounjaro is available from £124.99 per month, subject to prescriber approval following your free online consultation. This transparent upfront pricing includes your medication, UK prescriber assessment, and discreet home delivery. We guarantee the lowest prices in the UK for genuine, licensed medications.

Treatment costs vary depending on your prescribed dose and duration. Most patients require 12-18 months of continuous treatment to achieve and maintain their weight loss goals. Your prescriber will discuss the expected treatment timeline during your consultation, considering your individual circumstances and weight loss targets.

Both medications represent a significant investment in your health, but clinical evidence demonstrates they're considerably more effective than older weight loss treatments. When comparing costs, consider the value of the clinical support provided, medication authenticity guarantees, and convenience of online prescribing services. Cured Pharmacy's superintendent pharmacist, Tarun Kumar (GPhC 2233073), ensures every prescription meets the highest UK standards.

Transparent Pricing and No Hidden Fees

Unlike some providers, we display exact pricing before you begin your consultation. There are no subscription lock-ins, hidden consultation fees, or unexpected charges. You'll know your monthly cost upfront, and you can pause or discontinue treatment at any time in consultation with your prescriber. We believe transparency builds trust and helps you make informed decisions about your healthcare.

Choosing Between Wegovy and Mounjaro: Clinical Considerations

Your UK prescriber will consider multiple factors when recommending between these treatments. Medical history plays a crucial role: certain conditions like personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 contraindicate both medications [3]. Previous experience with GLP-1 treatments, current medications, and specific health goals all influence the decision.

If you have type 2 diabetes alongside obesity, Mounjaro may offer additional glycaemic benefits due to its dual-receptor mechanism [1]. However, Wegovy has a longer track record in weight management specifically, with extensive real-world safety data accumulated since its approval. Some prescribers prefer starting with Wegovy due to this established evidence base.

Individual response varies significantly between patients. Some people achieve excellent results with Wegovy and experience minimal side effects, whilst others may respond better to Mounjaro's dual-action approach. If you don't achieve adequate weight loss (typically defined as 5% body weight reduction after 12 weeks at maintenance dose), your prescriber may recommend switching to the alternative medication [4].

At Cured Pharmacy, our clinical team takes time to understand your specific circumstances during the free online consultation. We consider your weight loss history, previous treatment attempts, lifestyle factors, and personal preferences. This individualised approach ensures you receive the most appropriate treatment for your needs, with ongoing support throughout your weight loss journey.

Scientific References

  1. Frías, J. P., et al. (2021). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes (SURPASS-2): A Randomised, Open-Label, Phase 3 Trial. The Lancet, 398(10295), 64-77. https://doi.org/10.1016/S0140-6736(21)01324-6
  2. Wilding, J. P. H., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989-1002. https://doi.org/10.1056/NEJMoa2032183
  3. Medicines and Healthcare products Regulatory Agency. (2023). Wegovy 2.4mg Solution for Injection in Pre-filled Pen: Summary of Product Characteristics. GOV.UK. https://products.mhra.gov.uk/
  4. National Institute for Health and Care Excellence. (2023). Semaglutide for Managing Overweight and Obesity [TA875]. NICE Guidance. https://www.nice.org.uk/guidance/ta875

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary, and weight loss outcomes depend on multiple factors including adherence to treatment, lifestyle modifications, and individual metabolic response.

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Faq

Which is better for weight loss, Wegovy or Mounjaro?
Clinical trials show Mounjaro (tirzepatide) produced greater average weight loss (22.5%) compared to Wegovy (14.9%), but individual results vary significantly. Your UK prescriber will recommend the most suitable option based on your medical history, treatment goals, and individual circumstances.
How quickly will I see results with Wegovy vs Mounjaro?
Most patients notice appetite reduction within 1-2 weeks of starting either medication, with measurable weight loss typically beginning after 4-6 weeks. Maximum effects occur at maintenance doses, usually reached after 4-5 months of gradual dose escalation.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, switching between these medications is possible under medical supervision. Your prescriber will determine the appropriate starting dose and monitor your response. Some patients switch if they experience inadequate weight loss or tolerability issues with their initial treatment.
Are Wegovy and Mounjaro results permanent?
Weight loss maintenance requires ongoing treatment and lifestyle modifications. Clinical trials show most patients regain weight after discontinuing these medications. Long-term treatment is typically necessary, combined with sustained dietary and exercise changes.
Do I need a prescription for Wegovy or Mounjaro in the UK?
Yes, both are prescription-only medications requiring clinical assessment by a UK-registered prescriber. At Cured Pharmacy, you complete a free online consultation reviewed by our clinical team before any prescription is issued.
What's the difference in side effects between Wegovy and Mounjaro?
Both medications share similar gastrointestinal side effects including nausea, diarrhoea, and constipation. Mounjaro showed slightly higher nausea rates (44% vs 40%) in trials, but individual tolerability varies. Both require gradual dose escalation to minimise symptoms.
How much does Wegovy vs Mounjaro cost at Cured Pharmacy?
Wegovy starts from £135.00 per month and Mounjaro from £124.99 depending on your prescribed dose. We guarantee the lowest UK prices with transparent upfront costs and no hidden fees. Final pricing is confirmed after your prescriber determines your appropriate dose.
Can I use Wegovy or Mounjaro if I don't have diabetes?
Yes, both medications are licensed in the UK for weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related health conditions, regardless of diabetes status. Your prescriber will assess your eligibility during consultation.
Which is better for weight loss results in the UK - Wegovy or Mounjaro?
Clinical trials show Mounjaro typically delivers greater weight loss results than Wegovy, with patients losing an average of 15-22% body weight on Mounjaro versus 10-15% on Wegovy. Both medications are available through Cured Pharmacy with UK-registered prescriber consultations to determine which suits your needs best.
Is Mounjaro cheaper than Wegovy in the UK?
Mounjaro starts from £124.99 at Cured Pharmacy, while Wegovy starts from £69 for lower doses but reaches £179 for the maintenance 2.4mg dose. When comparing equivalent weight loss results, Mounjaro often offers better value over a full treatment course, and both are eligible for £20 off your first order with code Weightlossnew.
Can I switch from Wegovy to Mounjaro for better weight loss results?
Yes, many patients switch from Wegovy to Mounjaro seeking enhanced weight loss results. Cured Pharmacy's UK prescribers can assess your treatment history and safely transition you between medications, adjusting dosing schedules to minimise side effects during the switch.
How quickly do Wegovy vs Mounjaro weight loss results show in the UK?
Most patients see initial weight loss within 4-6 weeks on either medication, though Mounjaro users often report faster results. Cured Pharmacy provides ongoing support throughout your treatment journey with regular check-ins to monitor your progress on whichever medication your prescriber recommends.
Are Wegovy and Mounjaro available on the NHS for weight loss?
NHS availability is extremely limited with long waiting lists for both medications. Cured Pharmacy offers private prescriptions for Wegovy and Mounjaro with fast approval, starting from £124.99 for Mounjaro and £69 for Wegovy, allowing you to begin treatment immediately rather than waiting months.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Last reviewed: 17 July 2026