Wegovy vs Mounjaro UK - Compare Prices & Cheapest Option

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Cheapest Wegovy vs Mounjaro UK - Compare Prices

Compare Wegovy vs Mounjaro at the cheapest UK price from £124.99 — Save £20 with code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Wegovy vs Mounjaro UK: Complete Comparison Guide for Weight Loss

When comparing Wegovy vs Mounjaro UK options, patients often ask which injectable delivers superior weight loss results and better value. Both medications have transformed obesity treatment in the UK, but they work through different mechanisms and offer distinct dosing schedules. This comprehensive guide examines the clinical evidence, side effect profiles, and cost considerations to help you make an informed choice under the guidance of a UK prescriber.

How Wegovy vs Mounjaro UK Medications Work Differently

The fundamental difference in Wegovy vs Mounjaro UK treatments lies in their receptor activity. Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics a single gut hormone to regulate appetite and slow gastric emptying [1]. Mounjaro contains tirzepatide, a dual GIP/GLP-1 receptor agonist that activates two incretin pathways simultaneously, potentially offering enhanced metabolic benefits [2].

In clinical practice, this dual-action mechanism may explain why Mounjaro demonstrated superior weight loss in head-to-head trials. The SURPASS-2 study showed tirzepatide participants lost up to 15.7% body weight at the highest dose, compared to 5.7% with semaglutide 1mg [3]. However, Wegovy uses a higher semaglutide dose (2.4mg) than tested in that trial, with STEP trials showing average weight loss of 14.9% over 68 weeks [1].

Both medications require subcutaneous injection once weekly and work best alongside a reduced-calorie diet and increased physical activity. UK prescribers typically initiate treatment at the lowest dose and gradually escalate to minimise gastrointestinal side effects, a strategy supported by MHRA guidance for both products.

Receptor Mechanisms Explained

GLP-1 receptors in the brain's appetite centres reduce hunger signals and increase satiety after meals. GIP receptors, activated uniquely by Mounjaro, may improve insulin sensitivity and fat metabolism more effectively than GLP-1 alone [2]. This dual approach represents a significant advancement in pharmacological weight management, though long-term comparative data beyond two years remains limited for both treatments.

Wegovy vs Mounjaro UK Dosing Schedules Compared

The dosing progression differs significantly between Wegovy vs Mounjaro UK regimens. Wegovy follows a four-month escalation: starting at 0.25mg weekly, increasing to 0.5mg, then 1mg, 1.7mg, and finally the maintenance dose of 2.4mg weekly [1]. This gradual titration helps patients adapt to the medication and reduces the incidence of nausea and vomiting.

Mounjaro uses a simpler escalation schedule with five available doses: 2.5mg, 5mg, 7.5mg, 10mg, and 12.5mg weekly. Most UK prescribers start patients at 2.5mg and increase by 2.5mg increments every four weeks based on tolerability and weight loss response [3]. The flexibility to pause at intermediate doses makes Mounjaro particularly suitable for patients who experience side effects during titration.

Both medications come in pre-filled injection pens designed for self-administration. Wegovy pens contain four weekly doses, whilst Mounjaro pens are single-use. Proper injection technique and rotating injection sites between the abdomen, thigh, and upper arm are essential for optimal absorption and minimising injection site reactions.

Clinical Evidence: Wegovy vs Mounjaro UK Weight Loss Results

Direct comparison trials provide the strongest evidence when evaluating Wegovy vs Mounjaro UK effectiveness. The SURPASS-2 trial directly compared tirzepatide against semaglutide 1mg in adults with type 2 diabetes, showing tirzepatide 15mg produced 7.6kg greater weight loss after 40 weeks [3]. However, this study did not use Wegovy's full 2.4mg dose, limiting direct applicability to weight management patients.

The STEP programme evaluated semaglutide 2.4mg specifically for obesity treatment. STEP 1 demonstrated average weight loss of 14.9% versus 2.4% with placebo over 68 weeks, with 50.5% of participants achieving at least 15% weight reduction [1]. Cardiovascular outcomes also improved, with significant reductions in blood pressure and inflammatory markers.

Mounjaro's SURMOUNT-1 trial in adults with obesity (without diabetes) showed even more impressive results: average weight loss of 20.9% with the 15mg dose after 72 weeks, with 57% achieving at least 20% weight reduction [4]. These findings suggest Mounjaro may offer a modest advantage in absolute weight loss, though individual response varies considerably based on baseline metabolic health, adherence, and lifestyle factors.

Real-World UK Patient Outcomes

In our clinical experience at Cured Pharmacy, patients on both Wegovy vs Mounjaro UK treatments typically notice appetite reduction within the first two weeks. Weight loss becomes evident by week four, with the most significant changes occurring between months three and six. Patients who combine medication with structured dietary changes and regular physical activity consistently achieve results at the higher end of trial ranges, whilst those relying on medication alone see more modest benefits.

Feature Wegovy Mounjaro
Active Ingredient Semaglutide Tirzepatide
Mechanism GLP-1 agonist Dual GIP/GLP-1 agonist
Maintenance Dose 2.4mg weekly 5mg-15mg weekly
Average Weight Loss 14.9% (68 weeks) 20.9% (72 weeks)
Starting Price From £89 From £145
Injection Frequency Once weekly Once weekly
Titration Period 16-20 weeks 8-20 weeks
Common Side Effects Nausea, diarrhoea, constipation Nausea, diarrhoea, vomiting
MHRA Approved Yes (2023) Yes (2023)
Suitable for Type 2 Diabetes Yes Yes

Side Effects: Wegovy vs Mounjaro UK Tolerability Profile

The side effect profiles of Wegovy vs Mounjaro UK medications are broadly similar, with gastrointestinal symptoms being most common. In clinical trials, nausea affected 44% of Wegovy users and 34% of Mounjaro users at maintenance doses [1][3]. Diarrhoea, constipation, vomiting, and abdominal discomfort occur frequently during dose escalation but typically diminish after several weeks.

Serious adverse events remain rare with both treatments. Pancreatitis occurred in less than 0.2% of participants in major trials for both medications [1][4]. Gallbladder-related events, including cholelithiasis, appeared in 1.6% of Wegovy users and 1.4% of Mounjaro users during extended trials. UK prescribers routinely screen for personal or family history of medullary thyroid carcinoma and multiple endocrine neoplasia syndrome type 2 before initiating either treatment, as both carry theoretical thyroid C-cell tumour risk based on rodent studies.

Hypoglycaemia risk differs between the medications when used for weight loss in patients without diabetes. Wegovy carries minimal hypoglycaemia risk in this population, whilst Mounjaro's GIP activity may slightly increase risk, though this remains uncommon without concurrent insulin or sulfonylurea use [2][3]. Both medications can cause injection site reactions in approximately 5% of users, typically mild erythema or itching that resolves without intervention.

Wegovy vs Mounjaro UK Pricing and Value Comparison

Cost considerations significantly influence the Wegovy vs Mounjaro UK decision for many patients. At Cured Pharmacy, Wegovy starts from £124.99 per month, whilst Mounjaro begins at £124.99 monthly. Both prices include UK prescriber consultation, genuine medication, and discreet next-day delivery across the UK. New patients can access an additional £20 discount using code Weightlossnew, making initial treatment more accessible.

The price difference reflects several factors: Mounjaro's newer market entry, different manufacturing processes, and dual-receptor mechanism. However, if Mounjaro produces faster or greater weight loss for an individual patient, the higher upfront cost may deliver better long-term value through shorter treatment duration. Conversely, Wegovy's lower monthly cost makes extended treatment more financially sustainable for patients requiring 12-18 months of therapy to reach their goal weight.

Neither medication is routinely available on NHS prescription for weight management alone, though some Clinical Commissioning Groups may fund treatment for patients meeting strict BMI and comorbidity criteria. Most UK patients access these treatments privately, making transparent pricing essential. At Cured Pharmacy, all costs are displayed upfront before consultation, with no hidden fees or subscription traps that some online providers employ.

Long-Term Cost Considerations

When evaluating Wegovy vs Mounjaro UK value, consider total treatment duration. Clinical trials suggest most patients require 12-18 months to achieve optimal weight loss, followed by either maintenance therapy or careful monitoring during medication discontinuation [1][4]. A patient spending £124.99 monthly on Wegovy for 15 months invests £124.99 whilst Mounjaro at £124.99 monthly totals £124.99 over the same period. However, if Mounjaro enables goal achievement in 10 months versus 15 for Wegovy, the total costs converge. Individual response prediction remains imperfect, making this calculation speculative until several months into treatment.

Choosing Between Wegovy vs Mounjaro UK: Clinical Guidance

The optimal choice in the Wegovy vs Mounjaro UK decision depends on individual medical history, budget, and weight loss goals. Patients with type 2 diabetes may particularly benefit from Mounjaro's superior HbA1c reduction demonstrated in SURPASS trials, with average decreases of 2.0% versus 1.5% with semaglutide [3]. Those prioritising lowest cost whilst still achieving clinically significant weight loss often find Wegovy's proven efficacy at a lower price point more suitable.

Prescriber preference and experience also matter. Some UK clinicians favour Wegovy's longer market presence and more extensive real-world safety data, whilst others embrace Mounjaro's innovative dual-agonist approach and impressive trial results. At Cured Pharmacy, our clinical team led by Superintendent Pharmacist Tarun Kumar (GPhC 2233073) conducts thorough consultations to assess contraindications, previous weight loss attempts, and patient preferences before recommending either treatment.

Ultimately, both Wegovy vs Mounjaro UK medications represent evidence-based options for adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related comorbidities. Success with either treatment requires commitment to dietary modification, regular physical activity, and ongoing clinical monitoring. Patients who do not achieve at least 5% weight loss after 12-16 weeks at maintenance dose should discuss alternative strategies with their prescriber, as continued treatment may not be appropriate.

Scientific References

  1. Wilding, J. P., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., ... & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  2. Frias, J. P., Davies, M. J., Rosenstock, J., Pérez Manghi, F. C., Fernández Landó, L., Bergman, B. K., ... & SURPASS-2 Investigators. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. New England Journal of Medicine, 385(6), 503-515. [accessed 15 August 2026]
  3. Rosenstock, J., Wysham, C., Frías, J. P., Kaneko, S., Lee, C. J., Fernández Landó, L., ... & SURPASS-2 Investigators. (2021). Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial. The Lancet, 398(10295), 143-155. [accessed 15 August 2026]
  4. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., Wharton, S., Connery, L., Alves, B., ... & SURMOUNT-1 Investigators. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Which is better for weight loss, Wegovy vs Mounjaro UK?
Clinical trials suggest Mounjaro produces slightly greater average weight loss (20.9% vs 14.9%), though individual response varies significantly. Both are highly effective when combined with lifestyle changes and require prescriber assessment to determine suitability.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, patients can switch between Wegovy vs Mounjaro UK treatments under prescriber guidance. Your clinician will determine the appropriate starting dose based on your current regimen and tolerance, typically requiring a brief washout period.
How long does it take to see results with Wegovy vs Mounjaro UK?
Most patients notice reduced appetite within 1-2 weeks and measurable weight loss by week 4-6. Maximum weight loss typically occurs between months 6-12, with continued gradual reduction up to 18 months in clinical trials.
Are Wegovy vs Mounjaro UK available on NHS prescription?
NHS availability is extremely limited and varies by region. Most UK patients access these medications privately through registered pharmacies like Cured Pharmacy, where prescriber consultation and genuine medication are included in transparent upfront pricing.
What happens when I stop taking Wegovy or Mounjaro?
Weight regain is common after discontinuation, with studies showing patients regaining approximately two-thirds of lost weight within one year. Successful long-term maintenance requires sustained dietary and activity changes established during treatment.
Do Wegovy vs Mounjaro UK cause the same side effects?
Both medications share similar gastrointestinal side effects including nausea, diarrhoea, and constipation. Mounjaro's dual mechanism may cause slightly different tolerability patterns in some patients, though overall safety profiles are comparable.
Can I use Wegovy or Mounjaro if I have type 2 diabetes?
Yes, both Wegovy vs Mounjaro UK treatments are suitable for patients with type 2 diabetes and may improve glycaemic control. Mounjaro demonstrated superior HbA1c reduction in head-to-head trials, though both offer metabolic benefits beyond weight loss.
How much do Wegovy vs Mounjaro UK cost per month?
At Cured Pharmacy, Wegovy starts from £124.99 monthly and Mounjaro from £124.99 monthly, with new patients saving £124.99 using code Weightlossnew. Prices include UK prescriber consultation, genuine medication, and next-day delivery.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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