Mounjaro vs Wegovy UK - Compare Prices & Cheapest Option

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Cheapest Mounjaro vs Wegovy UK - Compare Prices

Compare Mounjaro and Wegovy at the cheapest UK price from £124.99 with £20 off using code Weightlossnew.

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Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£109 £89.00

£22.25 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £109
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy (Oral Pill)
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy (Oral Pill)
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy (Oral Pill)
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy (Oral Pill)
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Mounjaro vs Wegovy UK: Clinical Comparison and Which Is Right for You

When comparing Mounjaro vs Wegovy UK options for weight loss, patients often ask which medication delivers superior results. Both are GLP-1 receptor agonists licensed by the MHRA for chronic weight management, but Mounjaro (tirzepatide) also targets GIP receptors, whilst Wegovy (semaglutide) works through GLP-1 alone. Clinical trial data shows distinct differences in average weight loss, side effect profiles, and dosing schedules that influence which treatment suits individual patients best.

How Mounjaro vs Wegovy UK Medications Work Differently

The fundamental difference in Mounjaro vs Wegovy UK treatments lies in their receptor targeting mechanisms. Mounjaro contains tirzepatide, a dual GIP/GLP-1 receptor agonist that activates both glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 pathways [1]. Wegovy contains semaglutide, which selectively activates only GLP-1 receptors [2]. This dual-action mechanism gives Mounjaro a theoretical advantage in metabolic regulation, though both medications effectively suppress appetite, slow gastric emptying, and improve insulin sensitivity.

In the SURPASS-2 head-to-head trial comparing tirzepatide directly against semaglutide 1mg, patients taking the highest tirzepatide dose (15mg) achieved average weight loss of 11.2kg compared to 5.7kg with semaglutide over 40 weeks [1]. However, it's important to note that Wegovy uses a higher 2.4mg maintenance dose than the 1mg semaglutide tested in SURPASS-2. The STEP trials demonstrated Wegovy 2.4mg produced average weight loss of 14.9% body weight over 68 weeks [2], making direct comparisons complex. Both medications require gradual dose escalation to minimise gastrointestinal side effects and must be prescribed following clinical assessment by a UK-registered prescriber.

Mounjaro vs Wegovy UK Clinical Trial Results and Efficacy

When evaluating Mounjaro vs Wegovy UK efficacy data, the SURMOUNT-1 trial provides compelling evidence for tirzepatide's weight loss potential. Participants taking Mounjaro 15mg achieved average weight reduction of 20.9% body weight over 72 weeks, with 91% achieving at least 5% weight loss [3]. The lower 10mg maintenance dose still delivered 19.5% average weight loss, demonstrating consistent efficacy across dosing tiers. These results represent some of the highest weight loss percentages seen in any obesity medication trial to date.

Wegovy's STEP programme enrolled over 4,500 participants across multiple trials, with the pivotal STEP 1 study showing 14.9% average weight loss at 68 weeks on the 2.4mg maintenance dose [2]. Approximately 83.5% of participants achieved at least 5% weight loss, and 66.1% reached 10% or more. Whilst these figures are lower than Mounjaro's peak results, Wegovy has demonstrated sustained weight loss maintenance and cardiovascular benefits in the SELECT trial [4]. Both treatments significantly outperform older weight loss medications and require ongoing weekly injections to maintain results, subject to prescriber approval based on individual patient suitability.

Real-World Weight Loss Expectations

In clinical practice at Cured Pharmacy, our superintendent pharmacist Tarun Kumar GPhC 2233073 observes that individual responses to both Mounjaro vs Wegovy UK treatments vary considerably. Patients typically begin seeing measurable weight loss within 4-8 weeks of starting either medication, with maximum effects usually observed between months 6-12. Factors including baseline BMI, adherence to lifestyle modifications, starting dose tolerance, and metabolic health significantly influence outcomes. Neither medication guarantees specific results, and both work most effectively when combined with reduced-calorie nutrition and increased physical activity as part of a comprehensive weight management programme.

Side Effects: Mounjaro vs Wegovy UK Tolerability Profiles

The side effect profiles for Mounjaro vs Wegovy UK medications show substantial overlap, as both are GLP-1 receptor agonists affecting gastrointestinal function. The most common adverse effects for both treatments include nausea (reported in 20-44% of patients), diarrhoea, constipation, vomiting, and abdominal discomfort [1][2]. These symptoms typically peak during dose escalation phases and gradually diminish as the body adapts. Starting with lower doses and titrating slowly, as recommended in MHRA-approved protocols, significantly reduces the severity of gastrointestinal side effects.

In the SURPASS trials, tirzepatide showed slightly higher rates of nausea compared to semaglutide 1mg, though discontinuation rates due to adverse events remained below 7% for both medications [1]. Wegovy trials reported similar tolerability, with 4.5% of participants discontinuing due to gastrointestinal issues [2]. Rare but serious risks for both Mounjaro vs Wegovy UK treatments include pancreatitis, gallbladder disease, and potential thyroid C-cell tumours (contraindicated in patients with personal or family history of medullary thyroid carcinoma). Our UK clinical team conducts thorough medical history assessments before prescribing either medication to identify patients who may be at elevated risk.

Managing Common Side Effects

Patients can minimise side effects from either Mounjaro or Wegovy by eating smaller, more frequent meals, avoiding high-fat foods that delay gastric emptying further, staying well-hydrated, and injecting at consistent weekly intervals. If nausea becomes problematic, our pharmacists recommend taking the injection in the evening after a light meal and avoiding lying down immediately afterwards. Persistent or severe symptoms warrant consultation with your prescriber, who may adjust the dose escalation schedule or consider whether the treatment remains appropriate for your individual circumstances.

Feature Mounjaro (Tirzepatide) Wegovy (Semaglutide)
Active Ingredient Tirzepatide (GIP/GLP-1) Semaglutide (GLP-1 only)
Starting Dose 2.5mg weekly 0.25mg weekly
Maintenance Dose 10mg or 15mg weekly 2.4mg weekly
Average Weight Loss Up to 20.9% (SURMOUNT-1) Up to 14.9% (STEP 1)
Injection Frequency Once weekly Once weekly
Common Side Effects Nausea, diarrhoea, constipation Nausea, diarrhoea, constipation
Starting Price (UK) From £145.00/month From £89.00/month
MHRA Licensed Yes (2023) Yes (2022)

Dosing Schedules: Mounjaro vs Wegovy UK Administration

The dosing protocols for Mounjaro vs Wegovy UK treatments follow similar weekly injection schedules but differ in their escalation pathways and maintenance doses. Mounjaro begins at 2.5mg weekly for four weeks, then increases to 5mg for four weeks, with further escalations to 7.5mg, 10mg, 12.5mg, and a maximum of 15mg based on tolerability and weight loss response [1]. This gradual titration allows patients to adapt to increasing GIP/GLP-1 activity whilst minimising gastrointestinal disturbance.

Wegovy starts at 0.25mg weekly, doubling to 0.5mg after four weeks, then progressing through 1mg, 1.7mg, and finally the 2.4mg maintenance dose by week 17 [2]. Both medications use pre-filled injection pens administered subcutaneously in the abdomen, thigh, or upper arm. Patients can inject on any day of the week but must maintain the same day consistently. Missed doses should be taken within five days; if more time has elapsed, skip the dose and resume the regular schedule. Neither Mounjaro vs Wegovy UK treatment should be used alongside other GLP-1 medications, and both require ongoing prescription monitoring by UK healthcare professionals.

Mounjaro vs Wegovy UK Pricing and Value Comparison

When comparing Mounjaro vs Wegovy UK costs at Cured Pharmacy, pricing structures reflect the different dose escalation schedules and supply considerations. Mounjaro is available from £124.99 per month, whilst Wegovy starts from £124.99 per month, representing competitive UK pricing for both treatments [5]. New patients can Save £20 on their first order using code Weightlossnew, making either option more accessible during the initial trial period.

Long-term cost considerations for Mounjaro vs Wegovy UK treatments depend on the maintenance dose required for sustained weight loss. Patients achieving their target weight on lower Mounjaro doses (10mg) or standard Wegovy dosing (2.4mg) can optimise their monthly expenditure. Neither medication is routinely available on NHS prescription for weight loss alone unless specific criteria are met, meaning most UK patients access these treatments through private prescriptions. Cured Pharmacy provides transparent upfront pricing before consultation, with no hidden fees or subscription obligations. All prices include UK-registered prescriber assessment, genuine licensed medication, and discreet next-day delivery across the United Kingdom.

Insurance and NHS Availability

Currently, NHS England has restricted access to both Mounjaro and Wegovy due to supply constraints and budget limitations, with availability limited to specialist weight management services in some regions. Private health insurance coverage varies by provider and policy terms. Patients considering either Mounjaro vs Wegovy UK treatment through Cured Pharmacy benefit from fixed pricing, rapid online consultations completed in under three minutes, and direct access without lengthy waiting lists, subject to clinical suitability as determined by our UK-registered prescribers.

Which Is Better: Mounjaro vs Wegovy UK for Your Situation

Determining the superior choice in the Mounjaro vs Wegovy UK comparison depends on individual patient factors rather than a universal recommendation. Patients seeking maximum weight loss potential based on clinical trial data may lean towards Mounjaro, given the 20.9% average weight reduction seen in SURMOUNT-1 trials [3]. However, those prioritising established cardiovascular outcome data might prefer Wegovy, which demonstrated significant reductions in major adverse cardiovascular events in the SELECT trial [4]. Both medications require BMI ≥30 kg/m² (or ≥27 kg/m² with weight-related comorbidities) for appropriate prescribing under MHRA guidance.

Practical considerations also influence the Mounjaro vs Wegovy UK decision. Patients who experienced inadequate results or intolerable side effects on semaglutide-based treatments may respond better to tirzepatide's dual-receptor mechanism. Conversely, those already tolerating Wegovy well with satisfactory weight loss have little reason to switch. Cost sensitivity, injection frequency tolerance (both weekly), and individual metabolic responses all factor into treatment selection. At Cured Pharmacy, our clinical team evaluates medical history, current medications, contraindications, and patient preferences during the online consultation process to recommend the most appropriate option. Neither medication is inherently superior—the best choice is the one that delivers sustainable results with acceptable tolerability for your specific circumstances, as determined through shared decision-making with a qualified UK prescriber.

Scientific References

  1. Frías, J. P., Davies, M. J., Rosenstock, J., et al. (2021). Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. New England Journal of Medicine, 385(6), 503-515. [accessed 15 August 2026]
  2. Wilding, J. P., Batterham, R. L., Calanna, S., et al. (2021). Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine, 384(11), 989-1002. [accessed 15 August 2026]
  3. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide once weekly for the treatment of obesity. New England Journal of Medicine, 387(3), 205-216. [accessed 15 August 2026]
  4. Lincoff, A. M., Brown-Frandsen, K., Colhoun, H. M., et al. (2023). Semaglutide and cardiovascular outcomes in obesity without diabetes. New England Journal of Medicine, 389(24), 2221-2232. [accessed 15 August 2026]
  5. Medicines and Healthcare products Regulatory Agency. (2023). Public Assessment Report: Tirzepatide (Mounjaro). GOV.UK. [accessed 15 August 2026]
  6. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 15 August 2026.
  7. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 15 August 2026.
  8. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 15 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication.

Trusted by thousands

Real people, real results

Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Can I switch from Wegovy to Mounjaro or vice versa?
Yes, patients can switch between Mounjaro vs Wegovy UK treatments under prescriber guidance, though a washout period and dose adjustment may be necessary. Your clinician will determine the appropriate starting dose based on your previous treatment response and current tolerance.
Is Mounjaro more effective than Wegovy for weight loss?
Clinical trials show Mounjaro achieved higher average weight loss (20.9%) compared to Wegovy (14.9%), but individual results vary significantly. Both medications are highly effective when combined with lifestyle modifications, and the best choice depends on your specific medical profile and tolerability.
Do Mounjaro and Wegovy have the same side effects?
Both Mounjaro vs Wegovy UK medications share similar gastrointestinal side effects including nausea, diarrhoea, and constipation due to their GLP-1 activity. Severity and duration vary between individuals, with symptoms typically improving after the initial dose escalation period.
Which is cheaper in the UK: Mounjaro or Wegovy?
Wegovy starts from £124.99 per month at Cured Pharmacy, whilst Mounjaro starts from £124.99 per month. However, long-term value depends on the maintenance dose required and individual weight loss results achieved with each treatment.
Can I take Mounjaro and Wegovy together?
No, you should never combine Mounjaro vs Wegovy UK treatments or use them with any other GLP-1 receptor agonist medication. Taking both simultaneously increases the risk of severe side effects without additional benefit and is contraindicated.
How long does it take to see results with Mounjaro vs Wegovy?
Most patients notice initial weight loss within 4-8 weeks of starting either Mounjaro or Wegovy, with maximum effects typically observed between 6-12 months. Consistent weekly injections and lifestyle modifications are essential for optimal results with both treatments.
Are Mounjaro and Wegovy available on the NHS?
NHS access to both Mounjaro vs Wegovy UK treatments is currently limited due to supply constraints and funding restrictions. Most patients access these medications through private prescriptions from registered pharmacies like Cured Pharmacy, where transparent pricing and rapid consultations are available.
Do I need a prescription for Mounjaro or Wegovy in the UK?
Yes, both Mounjaro and Wegovy are prescription-only medicines in the UK requiring clinical assessment by a registered prescriber. Cured Pharmacy provides free online consultations completed in under three minutes, with same-day approval for eligible patients and discreet next-day delivery.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 15 August 2026

Last updated on 15 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 15 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (15 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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