Wegovy vs Mounjaro UK: Which Is Better? | Cured Pharmacy

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Wegovy vs Mounjaro UK - Cheapest Price From £69.00

Compare Wegovy and Mounjaro at the cheapest UK price from £124.99 plus £20 off first order with code Weightlossnew.

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Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy Oral Pill
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy Oral Pill
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy Oral Pill
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy Oral Pill
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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What Is The Difference Between Wegovy And Mounjaro?

Published on: June 03, 2026

Understanding the wegovy vs mounjaro uk comparison is essential when choosing a weight loss treatment that's right for you. Both are MHRA-licensed injectable medications that have transformed weight management outcomes in clinical trials, but they work through different mechanisms and produce different results. At Cured Pharmacy, our UK-registered clinical team can assess which treatment aligns with your medical history and weight loss goals.

How Wegovy and Mounjaro Work Differently

Wegovy contains semaglutide, a GLP-1 receptor agonist that mimics a single gut hormone to reduce appetite and slow gastric emptying [1]. It's been licensed in the UK since 2023 and works by activating GLP-1 receptors in the brain that regulate hunger signals.

Mounjaro contains tirzepatide, the first dual GIP/GLP-1 receptor agonist available in the UK [2]. This dual-action mechanism targets two separate hormone pathways simultaneously — both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) — which research suggests produces greater metabolic effects than single-pathway treatments.

The key clinical difference lies in this dual mechanism. By activating GIP receptors alongside GLP-1 receptors, tirzepatide appears to enhance insulin sensitivity and fat metabolism more effectively than semaglutide alone, though both medications require weekly subcutaneous injection and are subject to prescriber approval based on your BMI and medical history.

Clinical Trial Results: Wegovy vs Mounjaro Efficacy

In the landmark STEP 1 trial, adults taking Wegovy achieved an average 14.9% body weight reduction over 68 weeks when combined with lifestyle interventions [1]. Participants lost an average of 15.3kg compared to 2.6kg in the placebo group, with 83.5% achieving at least 5% weight loss.

The SURMOUNT-1 trial demonstrated even greater results with Mounjaro. Participants on the highest dose (15mg) achieved an average 22.5% body weight reduction over 72 weeks — approximately 24kg average weight loss [2]. At the 10mg maintenance dose, average weight loss was 21.4%, whilst the 5mg dose produced 16% average reduction.

Head-to-head comparison data remains limited, but these separate trials suggest tirzepatide may produce greater average weight loss than semaglutide in eligible patients. However, individual responses vary significantly, and your UK prescriber will consider factors beyond efficacy alone — including your tolerance to side effects, injection preferences, and medical contraindications — when recommending treatment.

Real-World Weight Loss Expectations

Clinical trial results represent average outcomes under controlled conditions with intensive lifestyle support. In real-world UK pharmacy practice, we observe that patients who maintain consistent dosing schedules and implement dietary changes typically achieve 12-20% body weight reduction over 12-18 months, though individual results vary considerably based on adherence, starting BMI, and metabolic factors.

Dosing Schedules and Administration

Both Wegovy and Mounjaro require once-weekly subcutaneous injection, typically in the abdomen, thigh, or upper arm. The injection process is identical — both use pre-filled single-dose pens that patients self-administer at home after receiving proper training from their prescriber or pharmacist.

Wegovy follows a fixed dose escalation: starting at 0.25mg weekly, increasing every four weeks through 0.5mg, 1mg, and 1.7mg, reaching the maintenance dose of 2.4mg by week 17 [3]. This gradual titration helps minimise gastrointestinal side effects as your body adjusts to the medication.

Mounjaro offers more flexible dosing with five available strengths: 2.5mg, 5mg, 7.5mg, 10mg, and 12.5mg or 15mg [4]. Treatment begins at 2.5mg weekly for four weeks, then increases to 5mg. Your prescriber may increase the dose in 2.5mg increments every four weeks based on your response and tolerability, up to a maximum of 15mg weekly. This flexibility allows more personalised dose optimisation than Wegovy's fixed schedule.

Injection Technique and Storage

Both medications must be refrigerated between 2-8°C until first use and can be kept at room temperature (below 30°C) for up to 21 days once removed from the fridge. Rotate injection sites weekly to prevent lipodystrophy, and never inject into areas that are tender, bruised, or scarred. The entire injection takes less than 10 seconds with either pen device.

Feature Wegovy (Semaglutide) Mounjaro (Tirzepatide)
Mechanism GLP-1 receptor agonist Dual GIP/GLP-1 receptor agonist
Average Weight Loss 14.9% over 68 weeks 22.5% over 72 weeks (15mg dose)
Dosing Frequency Once weekly injection Once weekly injection
Starting Dose 0.25mg weekly 2.5mg weekly
Maintenance Dose 2.4mg weekly 5-15mg weekly (flexible)
Most Common Side Effects Nausea (44%), diarrhoea (30%) Nausea (29-33%), diarrhoea (23-27%)
UK Price at Cured Pharmacy From £69.00 From £69.00
MHRA Licensed Since 2023 2023

Side Effects: What to Expect with Each Treatment

Both Wegovy and Mounjaro share similar side effect profiles because they work on overlapping GLP-1 pathways. The most common adverse effects are gastrointestinal: nausea, diarrhoea, vomiting, constipation, and abdominal discomfort [1][2]. These typically occur during dose escalation and often diminish as your body adapts to the medication.

In clinical trials, approximately 44% of Wegovy patients experienced nausea, compared to 29-33% with Mounjaro at therapeutic doses [1][2]. Diarrhoea occurred in 30% of Wegovy users versus 23-27% with Mounjaro. The dual-agonist mechanism in Mounjaro may produce slightly better gastrointestinal tolerability for some patients, though individual experiences vary considerably.

Serious but rare side effects include pancreatitis, gallbladder disease, and thyroid C-cell tumours (observed in animal studies). Both medications carry a boxed warning about potential thyroid tumours and are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 [3][4]. Always report persistent severe abdominal pain to your prescriber immediately.

Cost Comparison: Wegovy vs Mounjaro UK Pricing

At Cured Pharmacy, Wegovy starts from £135.00 per pen, making it one of the more accessible GLP-1 treatments available through UK online pharmacies. Mounjaro pricing starts from £124.99, reflecting its newer market entry and dual-mechanism formulation. Both prices include free clinical consultation with a UK prescriber, with final cost determined by your prescribed dose and treatment duration.

NHS availability for both medications remains limited to specialist weight management services in most regions, with strict eligibility criteria typically requiring BMI ≥35 with comorbidities or BMI ≥40. Private prescription through registered UK pharmacies like Cured Pharmacy offers faster access for eligible patients who meet clinical criteria but don't qualify for NHS provision.

When comparing total treatment costs, consider that weight loss medications require ongoing use to maintain results. Most patients remain on maintenance doses for 12-24 months or longer, so the cumulative cost difference between treatments becomes significant over time. Our transparent upfront pricing means you'll see exact costs before completing your consultation, with no hidden fees or subscription traps.

Insurance and Payment Options

Some private health insurance policies may cover weight loss medications when prescribed for obesity with comorbidities, though coverage varies significantly between providers. Check your policy documents or contact your insurer directly. Cured Pharmacy accepts all major payment methods and provides detailed receipts for insurance claims or flexible spending account reimbursement.

Which Treatment Is Right for You?

Choosing between Wegovy and Mounjaro depends on multiple clinical factors that your UK prescriber will assess during consultation. Mounjaro may be preferable if you're seeking maximum weight loss potential and can tolerate the higher cost, whilst Wegovy offers proven efficacy at a more accessible price point with slightly simpler dosing.

Your medical history plays a crucial role in treatment selection. Both medications are contraindicated in pregnancy, with personal or family history of medullary thyroid carcinoma, and in patients with severe gastrointestinal disease. If you're taking insulin or sulfonylureas, dose adjustments may be necessary to prevent hypoglycaemia when starting either treatment [3][4].

Previous experience with GLP-1 medications can inform your choice. Patients who've tried liraglutide (Saxenda) but found daily injections inconvenient often prefer weekly options like Wegovy or Mounjaro. If you've previously used Wegovy and plateaued despite good adherence, your prescriber may consider switching to Mounjaro's dual-agonist mechanism for additional weight loss, subject to clinical assessment and MHRA licensing restrictions.

Starting Your Weight Loss Journey at Cured Pharmacy

Our UK-registered clinical team, led by Superintendent Pharmacist Tarun Kumar (GPhC 2233073), provides comprehensive assessment to determine your eligibility for Wegovy, Mounjaro, or alternative treatments. The online consultation takes under three minutes and covers your medical history, current medications, weight loss goals, and any contraindications. If approved, your medication is dispensed from our GPhC-registered pharmacy (9012511) and delivered in discreet packaging, typically within 24-48 hours to UK addresses.

Scientific References

  1. Wilding, J. P. H., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183 [accessed 13 August 2026]
  2. Jastreboff, A. M., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038 [accessed 13 August 2026]
  3. Novo Nordisk. (2023). Wegovy (semaglutide) Summary of Product Characteristics. Medicines and Healthcare products Regulatory Agency. https://www.medicines.org.uk/emc/product/13799 [accessed 13 August 2026]
  4. Eli Lilly. (2023). Mounjaro (tirzepatide) Summary of Product Characteristics. Medicines and Healthcare products Regulatory Agency. https://www.medicines.org.uk/emc/product/14881 [accessed 13 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 13 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 13 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 13 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary. Weight loss medications are most effective when combined with a reduced-calorie diet and increased physical activity.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Which is more effective for weight loss, Wegovy or Mounjaro?
Clinical trials suggest Mounjaro produces greater average weight loss (22.5% vs 14.9%), though individual results vary significantly based on adherence, lifestyle factors, and metabolic response.
Can I switch from Wegovy to Mounjaro or vice versa?
Yes, switching between treatments is possible under prescriber supervision. Your UK clinician will determine appropriate starting doses and monitor for side effects during the transition period, typically allowing a washout period between medications.
Do Wegovy and Mounjaro have the same side effects?
Both share similar gastrointestinal side effects (nausea, diarrhoea, constipation), though clinical trials suggest slightly lower nausea rates with Mounjaro. Individual tolerance varies considerably between patients.
How long does it take to see results with Wegovy vs Mounjaro?
Most patients notice appetite reduction within 1-2 weeks and measurable weight loss by week 4-8. Maximum weight loss typically occurs between 60-72 weeks with consistent use and lifestyle modifications.
Is Mounjaro worth the extra cost compared to Wegovy?
The cost-effectiveness depends on your weight loss goals and response to treatment. Mounjaro's superior average weight loss in trials may justify the higher price for patients seeking maximum results, whilst Wegovy offers proven efficacy at better value.
Can I get Wegovy or Mounjaro on the NHS?
NHS availability is limited to specialist weight management services with strict eligibility criteria (typically BMI ≥35 with comorbidities). Private prescription through UK-registered pharmacies offers faster access for eligible patients.
What happens if I miss a dose of Wegovy or Mounjaro?
If you miss a dose and fewer than 5 days have passed, inject as soon as possible then resume your regular schedule. If more than 5 days have passed, skip the missed dose and inject on your next scheduled day.
Do I need to inject Wegovy and Mounjaro in the same place each week?
No, you should rotate injection sites weekly between abdomen, thigh, and upper arm to prevent lipodystrophy and ensure consistent absorption. Never inject into the same spot two weeks consecutively.
Which is cheaper in the UK - Wegovy or Mounjaro?
Wegovy starts from £69.00 for the 0.25mg dose, while Mounjaro starts from £124.99 for the 2.5mg dose at Cured Pharmacy. However, Mounjaro often delivers faster weight loss results, making it better value for many patients despite the higher starting price.
Can I switch from Wegovy to Mounjaro in the UK?
Yes, you can switch from Wegovy to Mounjaro after consulting with a prescriber. Cured Pharmacy offers free online consultations to review your treatment history and determine the appropriate Mounjaro starting dose based on your current Wegovy dosage and response.
Is Mounjaro more effective than Wegovy for weight loss?
Clinical trials show Mounjaro typically delivers greater average weight loss than Wegovy, with patients losing 15-22% body weight on Mounjaro versus 10-15% on Wegovy. Cured Pharmacy can help you compare both medications during your consultation to choose the most suitable option for your weight loss goals.
Does the cheapest UK price for Mounjaro include prescription fees?
Yes, Cured Pharmacy's price of £124.99 for Mounjaro 2.5mg includes the prescriber consultation, prescription, and medication. There are no hidden fees, and you can save an additional £20 off your first order using code Weightlossnew.
How long does Mounjaro take to work compared to Wegovy?
Both Mounjaro and Wegovy typically show initial weight loss within 4-8 weeks, but Mounjaro often produces faster results due to its dual-action mechanism. Cured Pharmacy provides ongoing support throughout your treatment to monitor progress with either medication and adjust doses as needed.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 13 August 2026

Last updated on 13 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 13 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (13 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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