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Zidoval (Metronidazole)

Zidoval (Metronidazole)

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Zidoval Metronidazole Gel for Bacterial Vaginosis Treatment

 

Zidoval is a prescription vaginal gel containing metronidazole, an antibiotic specifically formulated to treat bacterial vaginosis (BV). This condition occurs when the natural balance of bacteria in your vagina becomes disrupted, leading to symptoms such as unusual discharge, odour, and discomfort. The gel is applied directly to the affected area, allowing the active ingredient to work locally where it's needed most.

Manufactured by Numark, Zidoval provides targeted treatment that helps restore your vaginal health. The gel formulation ensures the medication stays in contact with the affected tissues for optimal therapeutic effect. You can find additional women's health treatments to support your overall wellbeing alongside this prescription medication.

 

How Metronidazole Works Against Bacterial Infections

 

Metronidazole belongs to a group of antibiotics called nitroimidazoles. It works by entering bacterial cells and interfering with their DNA, preventing them from reproducing and ultimately destroying the harmful bacteria causing your infection. This targeted action helps eliminate the overgrowth of anaerobic bacteria responsible for bacterial vaginosis.

The metronidazole gel formulation allows for direct application to the vaginal area, ensuring high concentrations of the antibiotic reach the site of infection. This localised approach can be more effective than oral antibiotics for treating BV, as it delivers the medication exactly where it's needed whilst minimising systemic exposure.

 

Who Should Use Zidoval Gel

 

Zidoval is suitable for women diagnosed with bacterial vaginosis by their healthcare provider. Your doctor will typically diagnose BV based on your symptoms and may perform tests to confirm the condition before prescribing this treatment.

This medication is appropriate for you if you experience:

  • Unusual vaginal discharge with a fishy odour
  • Greyish-white or yellow discharge
  • Vaginal itching or irritation
  • Burning sensation during urination

 

Why Choose Topical Antibiotic Treatment

 

Vaginal gel formulations like Zidoval offer several advantages over oral antibiotics for treating bacterial vaginosis. The direct application means higher concentrations of the active ingredient reach the infection site, potentially improving treatment effectiveness. Additionally, topical treatment typically results in fewer systemic side effects compared to oral medications.

The gel base also provides a soothing effect and helps maintain moisture in the vaginal area during treatment. This can help reduce discomfort associated with BV symptoms whilst the antibiotic works to eliminate the bacterial overgrowth.

 

Clinical Suitability and Storage Requirements

 

Before using Zidoval, inform your healthcare provider about any other medications you're taking, particularly blood-thinning medications like warfarin, as metronidazole can enhance their effects. You should also mention if you're pregnant, breastfeeding, or planning to become pregnant, as your doctor will need to assess the benefits and risks.

Store Zidoval at room temperature, away from direct sunlight and moisture. Keep the tube tightly closed when not in use and ensure it's stored out of reach of children. Do not use the gel beyond its expiry date, and dispose of any unused medication safely through your local pharmacy's disposal service.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

 

How to Apply Zidoval Gel Correctly

Your doctor will provide specific instructions for using Zidoval based on your individual condition. The gel is typically applied using the applicator provided with the medication. Wash your hands thoroughly before and after application, and ensure the applicator is clean before use. Insert the applicator gently into your vagina and squeeze the tube to release the prescribed amount of gel.

Treatment Duration and Timing

Complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before finishing the medication. This ensures the infection is fully cleared and reduces the risk of recurrence. Apply the gel at the same time each day to maintain consistent levels of the antibiotic in the affected area. Avoid using tampons during treatment as they may absorb the medication and reduce its effectiveness.

Understanding Potential Side Effects of Zidoval

Like all medicines, Zidoval can have side effects, although not everyone will experience them. If you're managing other health conditions, you may find additional support through our thrush treatments if you develop secondary infections during antibiotic use.

The most common side effects are usually mild and affect the area where you apply the gel. These typically resolve once your treatment course is complete and your body adjusts to the medication.

Known side effects may include:

  • Vaginal irritation or burning sensation
  • Itching in the vaginal area
  • Unusual vaginal discharge
  • Pelvic pain or discomfort
  • Headache
  • Nausea
  • Metallic taste in your mouth
  • Dizziness
  • Abdominal pain
  • Skin rash or allergic reaction
  • Changes in menstrual cycle
  • Thrush or yeast infection

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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