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Vagisan Moisturising Cream For Vaginal Dryness - 50g

Vagisan Moisturising Cream For Vaginal Dryness - 50g

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  • ✔️ Relieves vaginal dryness, itching, and intimate irritation effectively
  • ✔️ Hormone-free formula safe for post-menopausal and cancer-treated women
  • ✔️ Suitable for both internal and external vaginal application
  • ✔️ Restores natural vaginal moisture balance without oestrogen
  • ✔️ Long-lasting moisturisation with use every two to three days

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What Is Vagisan Moisturising Cream for Vaginal Dryness?

 

Vaginal dryness is far more common than many people realise. It affects a significant number of women, particularly during and after the menopause, though it can occur at any age due to hormonal changes, breastfeeding, certain medications, or stress. If you've been experiencing discomfort, itching, or irritation in the intimate area, you're certainly not alone — and there are effective options available without a prescription. Vagisan Moisturising Cream is a hormone-free, water-miscible cream designed to restore moisture to the vaginal tissues and relieve the uncomfortable symptoms that come with dryness. You can explore a wider range of products for intimate and women's health concerns at Cured Pharmacy.

Vagisan Moisturising Cream comes in a 50g tube and is available over the counter, meaning no prescription is needed. It's suitable for long-term use and can be applied both internally (using the included applicator) and externally around the vaginal entrance. At £14.79, it offers a straightforward, clinically recognised approach to managing intimate dryness.

 

How Does Vagisan Moisturising Cream Work?

 

The cream works by delivering sustained moisture directly to the vaginal mucosa — the delicate lining of the vaginal canal. Unlike lubricants, which provide only short-term relief during intercourse, this cream is formulated for regular use to address the underlying dryness itself. Here's how it works:

  • Its water-miscible base closely mimics the body's natural vaginal secretions, helping to restore a comfortable moisture balance.
  • It forms a thin, protective film over the vaginal tissues, reducing friction and irritation.
  • It supports the natural slightly acidic vaginal pH, which is important for maintaining intimate health.
  • Because it contains no hormones, it does not interfere with the body's hormonal balance.

The result is gradual, sustained relief from dryness, itching, and soreness — rather than a quick fix that wears off within minutes.

 

Who Should Use Vagisan Moisturising Cream?

 

This cream is suitable for a wide range of women experiencing vaginal dryness for various reasons. It's particularly well-suited to those who prefer or require a hormone-free option. You might benefit from it if you:

  • Are going through the perimenopause or menopause and experiencing vaginal dryness or atrophy.
  • Are breastfeeding and noticing intimate dryness due to lower oestrogen levels.
  • Have had breast cancer treatment and cannot use hormonal therapies.
  • Experience dryness as a side effect of certain medications, such as antihistamines or antidepressants.

It is not intended for use in children. If you are pregnant, speak to your GP or midwife before using any vaginal product.

 

How Does Vagisan Moisturising Cream Compare to Other Vaginal Moisturisers?

 

Feature Vagisan Moisturising Cream Replens Long-Lasting Moisturiser
Hormone-free Yes Yes
Application method Internal applicator or external fingertip Internal applicator only
Frequency of use Every 2–3 days or as needed Every 3 days
Suitable for external use Yes No

 

Is Vagisan Moisturising Cream Suitable for Sensitive Skin?

 

Yes — the formulation is designed with sensitive intimate skin in mind. It is fragrance-free, preservative-free, and does not contain hormones, making it a gentle choice for women with sensitive skin or those prone to reactions. If you have a known allergy to any of the listed ingredients, do not use this product and consult your pharmacist. For those managing other skin-related concerns alongside intimate dryness, our skin care collection may also be of interest.

As a vaginal dryness cream, Vagisan is one of the more versatile options available — it can be used both internally and externally, which sets it apart from many comparable products on the market.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Vagisan Moisturising Cream For Vaginal Dryness 50g specifications
Treatment category Vaginal dryness / intimate moisturiser
Mechanism of action Water-miscible base restores vaginal moisture and supports natural pH
Effective for Vaginal dryness, itching, irritation, discomfort during intercourse
Suitable for Adult women; menopausal and post-menopausal women; hormone-free use
Active ingredient Water-miscible cream base (aqueous, lactic acid-buffered)
Pack size 50g tube with applicator
UK classification General Sale / OTC
Drug class Vaginal moisturiser (non-hormonal)
Preparation Cream
Route of administration Vaginal (internal) and topical (external)

Specifications of Vagisan Moisturising Cream For Vaginal Dryness 50g

 

What Is Vagisan Moisturising Cream and What Is It Used For?

 

Vagisan Moisturising Cream is a non-hormonal, water-miscible vaginal moisturiser used to relieve the symptoms of vaginal dryness. These symptoms can include itching, burning, soreness, and discomfort during sexual intercourse. The cream is suitable for regular use and is particularly helpful for women experiencing vaginal atrophy — a thinning and drying of the vaginal walls — which is a common consequence of falling oestrogen levels during the menopause. According to the NHS, vaginal dryness is a very common menopausal symptom that can significantly affect quality of life and intimate relationships.

The cream can be applied both internally using the supplied applicator and externally around the vaginal entrance. It is available without a prescription and is suitable for long-term use as part of a regular intimate care routine.

 

What Do You Need to Know Before Using Vagisan Moisturising Cream?

 

Before using this cream, it's important to be aware of the following contraindications and warnings:

  • Do not use if you are allergic to any of the ingredients listed in the product leaflet.
  • Do not use in children or adolescents under 18 years of age.
  • If you are pregnant or breastfeeding, consult your GP or midwife before use.
  • If you have unexplained vaginal bleeding, unusual discharge, or pelvic pain, see your GP before using any vaginal product.
  • Do not use if you have an active vaginal infection — treat the infection first. If you suspect thrush, our thrush treatments collection may help.
  • Discontinue use and consult a healthcare professional if symptoms worsen or do not improve within 4 weeks.

Regarding interactions with other products:

  • Vagisan Moisturising Cream may damage latex condoms and diaphragms, potentially reducing their contraceptive effectiveness.
  • Avoid using alongside other vaginal products at the same time unless advised by a healthcare professional.
  • No significant systemic drug interactions are known due to its non-hormonal, topical nature.

 

How Should You Use Vagisan Moisturising Cream?

 

Using the cream correctly will help you get the most benefit. Follow these steps:

  1. Wash your hands thoroughly before and after application.
  2. For internal use, attach the applicator to the tube, squeeze a small amount of cream into the applicator, insert gently into the vagina, and press the plunger to release the cream.
  3. For external use, apply a small amount directly to the vaginal entrance and surrounding skin using a clean fingertip.
  4. Use every 2 to 3 days, or more frequently if needed, ideally at bedtime to allow the cream to absorb overnight.
  5. Replace the cap on the tube after each use.
Indication Age Group Dose Frequency
Vaginal dryness (internal) Adult women One applicator dose (~2.5g) Every 2–3 days
External irritation / itching Adult women Small fingertip amount As needed, up to daily

 

What Are the Possible Side Effects of Vagisan Moisturising Cream?

 

Vagisan Moisturising Cream is generally well tolerated. Side effects are uncommon, but as with any topical product, some women may experience a reaction. If you notice any of the following, stop using the cream and speak to your pharmacist or GP.

Common side effects:

  • Mild local irritation at the site of application
  • Temporary burning or stinging sensation immediately after application

Less common side effects:

  • Redness or swelling of the vaginal area
  • Increased vaginal discharge
  • Allergic skin reaction (rash, itching, hives) — stop use immediately if this occurs

Serious allergic reactions are rare but possible. If you experience swelling of the face, lips, or throat, or have difficulty breathing, seek emergency medical attention immediately.

 

How Should You Store Vagisan Moisturising Cream?

 

Correct storage helps maintain the quality and safety of the cream. Follow these guidelines:

  • Store below 25°C in a cool, dry place.
  • Do not freeze.
  • Keep the tube tightly closed when not in use.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the tube or carton.
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy.

If you're managing multiple aspects of your intimate health, you may also find our personal lubricants collection a useful complement to this cream for use during intercourse.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Vagisan Moisturising Cream online in the UK?

You can buy Vagisan Moisturising Cream 50g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £14.79. No prescription is required as it is an over-the-counter product. It's available for delivery across the UK, making it a convenient option if you'd prefer to order discreetly from home.

How does Vagisan Moisturising Cream work in the body?

Vagisan Moisturising Cream uses a water-miscible base that closely mimics the body's natural vaginal secretions, replenishing moisture in the vaginal tissues. It forms a thin protective film over the vaginal mucosa, reducing friction, irritation, and dryness. Because it contains no hormones, it works purely through physical moisturisation rather than altering your hormonal balance.

How do I use Vagisan Moisturising Cream step by step?

For internal use, attach the applicator to the tube, fill it with a small amount of cream, insert gently into the vagina, and press the plunger. For external use, apply a small amount around the vaginal entrance using a clean fingertip. Use every 2 to 3 days, ideally at bedtime, and always wash your hands before and after application.

How often should I use Vagisan Moisturising Cream?

The recommended frequency is every 2 to 3 days for internal use, though you can apply it externally more often if needed for comfort. Many women find that using it at night allows the cream to absorb fully while they sleep. Adjust frequency based on your symptoms — some women need it daily initially, then reduce as symptoms improve.

Is Vagisan Moisturising Cream safe to use during menopause?

Yes, Vagisan Moisturising Cream is specifically designed for women experiencing vaginal dryness during and after the menopause. It is hormone-free, which makes it suitable for women who cannot or prefer not to use oestrogen-based treatments. The NHS recognises non-hormonal vaginal moisturisers as a first-line option for managing menopausal vaginal dryness.

Can I use Vagisan Moisturising Cream if I've had breast cancer?

Because Vagisan Moisturising Cream contains no hormones, it is generally considered suitable for women who have had breast cancer and cannot use hormonal therapies. However, you should always discuss any new product with your oncologist or GP before starting use, particularly if you are currently undergoing treatment.

Can Vagisan Moisturising Cream be used with condoms?

Vagisan Moisturising Cream may weaken latex condoms and diaphragms, which could reduce their effectiveness as contraception. If you use latex barrier methods, speak to your pharmacist about alternatives. Non-latex condoms are generally unaffected, but always check the product labelling to be sure.

What are the side effects of Vagisan Moisturising Cream?

Side effects are uncommon but may include mild local irritation, a temporary burning sensation, or redness after application. Allergic reactions are rare but possible — if you notice swelling, hives, or difficulty breathing, stop use immediately and seek medical attention. If mild irritation persists beyond a few days, consult your pharmacist or GP.

How long can you use Vagisan Moisturising Cream for?

Vagisan Moisturising Cream is suitable for long-term, ongoing use as a regular vaginal moisturiser. There is no set maximum duration, and many women use it continuously as part of their intimate care routine. If your symptoms do not improve after 4 weeks of regular use, it's worth speaking to your GP to rule out other underlying causes.

What is the difference between Vagisan Moisturising Cream and a personal lubricant?

A vaginal moisturiser like Vagisan is designed for regular use to treat persistent dryness by restoring moisture to the vaginal tissues over time. A personal lubricant, on the other hand, is typically used immediately before or during sexual activity to reduce friction in the short term. Both can be used together — you can browse our personal lubricants collection for complementary options.

Is Vagisan Moisturising Cream the same as a vaginal dryness cream with hormones?

No — Vagisan Moisturising Cream is entirely hormone-free and works through physical moisturisation rather than hormonal action. Hormonal vaginal creams (such as those containing oestrogen) are prescription-only medicines and work differently by restoring oestrogen levels locally. Vagisan is a suitable alternative for those who prefer or require a non-hormonal approach.

Who is eligible to use Vagisan Moisturising Cream?

Vagisan Moisturising Cream is suitable for adult women experiencing vaginal dryness from any cause, including menopause, breastfeeding, medication side effects, or stress. It is not suitable for use in children or adolescents under 18. Pregnant women should consult their GP or midwife before use.

What happens if I use too much Vagisan Moisturising Cream?

Using more cream than recommended is unlikely to cause serious harm, but it may cause temporary discomfort, increased discharge, or local irritation. Stick to the recommended dose — one applicator dose internally every 2 to 3 days — and reduce the amount if you notice any irritation. If you are concerned, speak to your pharmacist.

What are the alternatives to Vagisan Moisturising Cream?

Other non-hormonal vaginal moisturisers available in the UK include Replens Long-Lasting Moisturiser and Yes VM vaginal moisturiser. For women whose dryness is related to menopause and who are able to use hormonal treatments, prescription vaginal oestrogen preparations are also an option — discuss this with your GP. You can also explore our broader women's health range for related products.

What does the latest research say about non-hormonal vaginal moisturisers?

Clinical evidence supports the use of non-hormonal vaginal moisturisers as an effective first-line treatment for vaginal dryness, particularly in women who cannot use hormonal therapies. The NHS and NICE both recommend them as a safe and appropriate option for managing genitourinary symptoms of menopause. Research continues to confirm that regular use improves vaginal comfort, pH balance, and quality of life in affected women.

How Should You Use Vagisan Moisturising Cream?

Using Vagisan Moisturising Cream correctly makes a real difference to how well it works. Always read the patient information leaflet supplied with the product before use, and follow these steps carefully.

If you experience any discomfort during internal application, stop and consult your pharmacist or GP before continuing.

What Is the Correct Dose of Vagisan Moisturising Cream?

The dose varies slightly depending on whether you are using the cream internally or externally. The table below summarises the recommended doses for adult women. Do not exceed the amounts listed — using more cream does not improve results and may cause unnecessary irritation.

When Is the Best Time to Use Vagisan Moisturising Cream?

Most women find that applying Vagisan Moisturising Cream at bedtime gives the best results. Using it at night allows the cream to remain in contact with the vaginal tissues for longer without being disturbed by movement or clothing, giving it the best chance to absorb and provide sustained relief. If you are using it before sexual activity, apply it well in advance — ideally several hours beforehand — rather than immediately before, as it is a moisturiser rather than a lubricant.

Consistency matters more than timing. Applying the cream regularly every 2 to 3 days, even when symptoms feel manageable, helps maintain moisture levels and prevents dryness from returning.

How Long Can You Use Vagisan Moisturising Cream For?

Vagisan Moisturising Cream is suitable for long-term, ongoing use. Unlike some topical treatments, there is no recommended maximum duration — many women use it continuously as part of their regular intimate care routine, particularly during and after the menopause when vaginal dryness tends to be a persistent issue rather than a temporary one.

That said, if your symptoms have not improved after 4 weeks of regular use, it is worth speaking to your GP. Persistent vaginal dryness can sometimes have an underlying cause that warrants further investigation or a different treatment approach.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Vagisan Moisturising Cream?

Vagisan Moisturising Cream is generally very well tolerated, and most women use it without experiencing any side effects at all. However, as with any topical product applied to sensitive tissue, mild reactions can occasionally occur, particularly when you first start using it.

  • Mild local irritation at the site of application
  • Temporary burning or stinging sensation immediately after applying the cream
  • Slight increase in vaginal discharge in the first few days of use

These effects are usually short-lived and tend to settle on their own. If they persist beyond a few days, reduce the frequency of application and speak to your pharmacist.

What Are the Less Common Side Effects of Vagisan Moisturising Cream?

Less commonly, some women may notice more noticeable local reactions. These are still not serious in most cases, but they do warrant attention.

  • Redness or swelling of the vaginal area or vulva
  • Itching that worsens rather than improves after application
  • Skin rash or hives around the application site
  • Unusual vaginal discomfort that was not present before starting the cream

If any of these occur, stop using the cream and consult your pharmacist or GP. It is possible that you may have a sensitivity to one of the ingredients in the formulation.

What Are the Serious Side Effects of Vagisan Moisturising Cream?

Serious side effects are rare with Vagisan Moisturising Cream, but a severe allergic reaction (anaphylaxis) is possible with any topical product, even if it has been used before without issue. Signs of a serious allergic reaction include:

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Rapid heartbeat or feeling faint
  • Widespread skin rash or hives across the body

If you experience any of these symptoms, stop using the cream immediately and call 999 or go to your nearest A&E department without delay.

What Should You Do If You Experience Side Effects?

For mild side effects such as temporary irritation or stinging, try reducing the frequency of application and see if symptoms settle. Applying a smaller amount of cream may also help. If side effects are moderate or persistent — particularly itching, redness, or swelling — discontinue use and seek advice from your pharmacist or GP before continuing.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve the safety monitoring of medicines available in the UK.

Can Vagisan Moisturising Cream Interact With Other Medicines?

Because Vagisan Moisturising Cream is applied topically and contains no hormones, it does not have significant systemic drug interactions. However, there is one important practical interaction to be aware of: the cream's oil-free, water-miscible base can still affect the integrity of latex condoms and diaphragms, potentially reducing their effectiveness as contraception. If you use latex barrier methods, speak to your pharmacist about the best approach. No interactions with oral or systemic medicines have been identified.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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