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Hyalofemme Vaginal Moisturiser 30g

Hyalofemme Vaginal Moisturiser 30g

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  • ✔️ Relieves vaginal dryness with hyaluronic acid moisture retention
  • ✔️ Hormone-free formula suitable for women avoiding HRT
  • ✔️ Restores natural vaginal comfort in perimenopausal women
  • ✔️ Reduces itching, soreness, and discomfort during intercourse
  • ✔️ Long-lasting moisturisation with just three applications per week

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Is Hyalofemme the Right Vaginal Moisturiser for Menopause?

 

Vaginal dryness is one of the most common — and least talked about — symptoms of menopause. It affects a significant number of women during perimenopause and beyond, causing discomfort, itching, and pain during sex. If you've been searching for a vaginal moisturiser for menopause that doesn't contain hormones, Hyalofemme Vaginal Moisturiser 30g could be exactly what you need. It's a clinically recognised, non-hormonal gel designed to restore moisture and comfort to vaginal tissues. You can explore a wider range of products in our women's health collection if you're looking for additional support.

Vaginal dryness — clinically referred to as vaginal atrophy or genitourinary syndrome of menopause (GSM) — occurs when oestrogen levels fall. The vaginal lining becomes thinner, less elastic, and produces less natural lubrication. The NHS recognises this as a genuine medical concern that can significantly affect quality of life. Hyalofemme addresses this directly with a targeted, hormone-free approach.

 

How Does Hyalofemme Vaginal Moisturiser Work?

 

Hyalofemme works through the moisturising and water-retaining properties of sodium hyaluronate — the salt form of hyaluronic acid. Hyaluronic acid is a naturally occurring substance found throughout the body, including in skin and connective tissue. In the vaginal environment, it plays a key role in maintaining hydration and tissue integrity.

  • Sodium hyaluronate binds to water molecules in vaginal tissue, drawing moisture into the cells.
  • It forms a thin, protective film over the vaginal mucosa, reducing friction and irritation.
  • Regular use helps restore the natural moisture balance of the vaginal environment.
  • It supports the health of the vaginal epithelium without altering hormone levels.

Because it contains no oestrogen or other hormones, Hyalofemme is suitable for women who cannot use hormone replacement therapy (HRT) — including those with a history of hormone-sensitive conditions.

 

Who Should Use Hyalofemme Vaginal Moisturiser?

 

Hyalofemme is intended for adult women experiencing vaginal dryness, particularly those going through perimenopause or postmenopause. It's also used by women whose vaginal dryness has other causes, such as certain medications, breastfeeding, or cancer treatments that affect oestrogen levels.

  • Perimenopausal or postmenopausal women with vaginal dryness or discomfort
  • Women who prefer or require a hormone-free option
  • Women experiencing discomfort during sexual intercourse due to reduced lubrication
  • Those seeking a long-term, regular vaginal moisturiser rather than a short-term lubricant

It is not a contraceptive and should not be used as a substitute for a personal lubricant during intercourse if that is your primary need. For that purpose, you may wish to browse our personal lubricants collection.

 

How Does Hyalofemme Compare to Other Vaginal Moisturisers?

 

Feature Hyalofemme 30g Replens Long-Lasting Moisturiser
Active ingredient Sodium hyaluronate (hyaluronic acid) Polycarbophil
Hormone-free Yes Yes
Application frequency Typically 3 times per week Typically 3 times per week
Mechanism Hyaluronic acid hydration Bioadhesive polymer moisture retention

 

Is Hyalofemme Safe for Long-Term Use?

 

Hyalofemme is generally considered safe for ongoing use as a vaginal moisturiser for menopause symptoms. Sodium hyaluronate is well tolerated by most women and has a good safety profile in clinical use. Because it is hormone-free, there are no concerns about systemic hormonal effects with regular application.

If you have a known allergy to any of the ingredients, you should not use this product. Women with persistent or worsening symptoms despite regular use should speak to their GP, as further investigation may be needed to rule out other causes of vaginal discomfort. If you're managing multiple menopausal symptoms, it may also be worth looking at our vitamins and supplements range for complementary support.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Hyalofemme Vaginal Moisturiser 30g specifications
Treatment category Vaginal dryness / Genitourinary syndrome of menopause
Active ingredient Sodium hyaluronate (hyaluronic acid)
Mechanism of action Hydrophilic moisture retention via hyaluronic acid binding
Suitable for Adult women; perimenopausal and postmenopausal
Pack size 30g tube
UK classification General Sale / Medical Device
Preparation Vaginal gel
Route of administration Vaginal (topical)

Specifications of Hyalofemme Vaginal Moisturiser 30g

 

What Is Hyalofemme and What Is It Used For?

 

Hyalofemme Vaginal Moisturiser 30g is a non-hormonal vaginal gel used to relieve the symptoms of vaginal dryness. It is particularly indicated for women experiencing genitourinary syndrome of menopause (GSM) — a condition that causes the vaginal tissues to become dry, thin, and less elastic as oestrogen levels decline. Symptoms can include itching, burning, soreness, and discomfort during sexual intercourse.

The active ingredient, sodium hyaluronate, is a naturally derived molecule with well-established moisturising properties. Unlike HRT, Hyalofemme does not introduce hormones into the body. It works locally, directly at the site of dryness, making it a suitable option for women who cannot or choose not to use hormonal treatments. The NHS acknowledges vaginal dryness as a common and treatable menopausal symptom, and non-hormonal moisturisers are among the recommended first-line options.

 

What Do You Need to Know Before Using Hyalofemme?

 

Before using Hyalofemme, read the following carefully. While this product is generally well tolerated, there are some important considerations.

Do not use Hyalofemme if you:

  • Are allergic to sodium hyaluronate or any other ingredient in the formulation
  • Have an active vaginal infection — treat the infection first before using a moisturiser
  • Are under 18 years of age

Use with caution and speak to your doctor or pharmacist if you:

  • Have unexplained vaginal bleeding
  • Have a history of gynaecological cancer
  • Are pregnant or breastfeeding — seek medical advice before use
  • Have symptoms that are worsening despite regular use

Known drug interactions:

  • No significant drug interactions have been identified for topical sodium hyaluronate used vaginally.
  • If you are using other vaginal preparations (e.g. antifungal creams or pessaries), allow adequate time between applications and consult your pharmacist. You can find relevant products in our thrush treatment collection.

 

How Should You Use Hyalofemme Vaginal Moisturiser?

 

Always use Hyalofemme exactly as described in the product leaflet or as directed by your healthcare professional. The gel is applied vaginally using the applicator provided in the pack.

  1. Wash your hands thoroughly before and after use.
  2. Fill the applicator with the recommended amount of gel as indicated on the applicator barrel.
  3. Lie on your back with your knees bent, or stand with one foot raised on a step.
  4. Gently insert the applicator into the vagina as far as is comfortable.
  5. Press the plunger slowly to release the gel.
  6. Remove the applicator and dispose of it or clean it according to the manufacturer's instructions.
Indication Age Group Dose Frequency
Vaginal dryness (menopause) Adult women One applicatorful (approx. 5g) 3 times per week
Maintenance / ongoing use Adult women One applicatorful As directed by healthcare professional

 

What Are the Possible Side Effects of Hyalofemme?

 

Like all medicines and medical devices, Hyalofemme may cause side effects in some women, although not everyone experiences them. Most side effects are mild and localised.

Common side effects:

  • Mild localised irritation at the site of application
  • Temporary sensation of warmth or tingling after insertion

Less common side effects:

  • Transient burning or stinging sensation
  • Increased vaginal discharge (usually temporary)
  • Allergic reaction — stop use immediately if you notice rash, swelling, or severe irritation

If you experience any side effect that concerns you, or if symptoms worsen, stop using the product and speak to your pharmacist or GP. Serious allergic reactions are rare but require prompt medical attention.

 

How Should You Store Hyalofemme Vaginal Moisturiser?

 

Correct storage helps maintain the product's effectiveness and safety throughout its shelf life.

  • Store below 25°C in a cool, dry place
  • Do not freeze
  • Keep the tube tightly closed when not in use
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the tube or carton
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

If you're managing other aspects of your health alongside vaginal dryness, you may find it helpful to explore our women's health range for further support options.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Hyalofemme Vaginal Moisturiser online in the UK?

You can buy Hyalofemme Vaginal Moisturiser 30g directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter product. Simply add it to your basket and choose your preferred delivery option at checkout.

How does Hyalofemme work for vaginal dryness?

Hyalofemme contains sodium hyaluronate, a form of hyaluronic acid that attracts and retains water molecules within vaginal tissue. This helps restore natural moisture levels and reduces the discomfort, itching, and soreness associated with vaginal dryness. It works locally without affecting hormone levels anywhere else in the body.

How do I use Hyalofemme step by step?

Wash your hands, fill the applicator with gel, and gently insert it into the vagina while lying down or standing with one foot raised. Press the plunger to release the gel, then remove and clean or dispose of the applicator. Always follow the instructions in the product leaflet or as advised by your pharmacist.

How often should I use Hyalofemme Vaginal Moisturiser?

The standard recommended frequency is three times per week, though your doctor or pharmacist may suggest a different schedule based on your individual symptoms. Consistent, regular use tends to give the best results for ongoing vaginal dryness relief. Do not use more frequently than advised without speaking to a healthcare professional first.

What are the side effects of Hyalofemme?

Side effects are uncommon but can include mild localised irritation, a temporary burning or tingling sensation, or a slight increase in vaginal discharge shortly after application. These effects are usually short-lived and resolve on their own. If you experience persistent discomfort or signs of an allergic reaction, stop use and contact your pharmacist or GP.

Is Hyalofemme suitable for postmenopausal women?

Yes — Hyalofemme is specifically designed for women experiencing vaginal dryness related to menopause, including both perimenopausal and postmenopausal women. It is hormone-free, which makes it a suitable choice for those who cannot or prefer not to use HRT. Women with a history of hormone-sensitive conditions may find it a particularly appropriate option.

Can I use Hyalofemme if I am not going through menopause?

Vaginal dryness can occur for reasons other than menopause, including breastfeeding, certain medications, or cancer treatments that lower oestrogen levels. Hyalofemme may be used in these situations, but it is always advisable to speak to your GP or pharmacist first to confirm the cause of your symptoms. Self-treating without understanding the underlying cause is not recommended.

Is Hyalofemme a lubricant or a moisturiser — what is the difference?

Hyalofemme is a vaginal moisturiser, not a personal lubricant. Moisturisers are used regularly (several times a week) to maintain ongoing hydration of vaginal tissue, whereas lubricants are typically used immediately before or during sexual intercourse for short-term comfort. If you need a lubricant for intercourse, browse our personal lubricants collection for suitable options.

Can I use Hyalofemme with condoms?

Hyalofemme is a water-based gel and is generally considered compatible with latex condoms, but it is not specifically designed for use as a lubricant during intercourse. Always check the product leaflet or speak to your pharmacist if you are unsure about compatibility with contraceptive products. For sexual health products, you can also visit our condoms and sexual health collection.

How long does it take for Hyalofemme to work?

Some women notice an improvement in comfort within the first few applications, but the full benefit of regular use typically becomes apparent after two to four weeks of consistent use three times per week. Vaginal tissue takes time to rehydrate and recover, so patience and regularity are important. If you see no improvement after four to six weeks, speak to your GP.

How long can I use Hyalofemme for?

Hyalofemme can be used long-term as an ongoing vaginal moisturiser, as vaginal dryness associated with menopause is often a persistent condition rather than a temporary one. There is no set maximum duration of use, but you should review your symptoms periodically with your GP or pharmacist. If symptoms change or worsen, seek medical advice promptly.

What happens if I miss an application of Hyalofemme?

If you miss an application, simply use it at your next scheduled time — do not double up to compensate for a missed dose. Missing the occasional application is unlikely to cause significant problems, but consistent use gives the best results. Try to build it into a regular routine to make it easier to remember.

What are the alternatives to Hyalofemme for vaginal dryness?

Alternatives include other non-hormonal vaginal moisturisers such as Replens (polycarbophil-based), as well as hormonal options like topical oestrogen creams or pessaries available on prescription. The NHS also recommends lifestyle measures such as avoiding perfumed soaps and using unperfumed emollients. Speak to your GP to find the most appropriate option for your individual circumstances.

Is Hyalofemme safe to use during breastfeeding?

Vaginal dryness can occur during breastfeeding due to reduced oestrogen levels, and a non-hormonal moisturiser like Hyalofemme may be considered. However, you should always consult your GP or midwife before using any new product while breastfeeding. They can confirm whether it is appropriate for your specific situation.

What are the latest studies on hyaluronic acid for vaginal dryness?

Published clinical research has shown that vaginal hyaluronic acid preparations can be as effective as low-dose topical oestrogen for relieving symptoms of vaginal dryness in postmenopausal women, making them a credible hormone-free alternative. Studies have generally reported good tolerability and patient satisfaction with regular use. NICE guidelines on menopause also acknowledge non-hormonal vaginal moisturisers as a recommended treatment option.

How Should You Use Hyalofemme Vaginal Moisturiser?

Hyalofemme is applied vaginally using the applicator provided in the pack. Always wash your hands thoroughly before and after use to maintain good hygiene and reduce the risk of introducing bacteria into the vaginal area.

Follow these steps each time you use Hyalofemme:

Many women find it easiest to use Hyalofemme at bedtime, as lying down after application allows the gel to distribute evenly without leakage. Wearing a panty liner can help manage any minor discharge.

What Is the Correct Dose of Hyalofemme?

The standard dose is one applicatorful of gel (approximately 5g) per application. Do not exceed this amount per application unless specifically advised by your healthcare professional.

When Is the Best Time to Use Hyalofemme?

There is no strict requirement to use Hyalofemme at a specific time of day, but most women find bedtime the most convenient and comfortable option. Applying the gel before sleep reduces the chance of leakage and allows the hyaluronic acid to work undisturbed overnight.

Try to space your three weekly applications evenly — for example, Monday, Wednesday, and Friday — to maintain consistent moisture levels in the vaginal tissue throughout the week. Consistency matters more than the exact time of day.

How Long Can You Use Hyalofemme For?

Hyalofemme can be used as a long-term, ongoing vaginal moisturiser. Because vaginal dryness associated with menopause is often a chronic condition, many women use it indefinitely as part of their regular intimate health routine. There is no defined maximum treatment duration.

That said, you should review your symptoms with your GP or pharmacist periodically — particularly if you notice any changes, worsening of symptoms, or new vaginal discomfort. If your symptoms do not improve after four to six weeks of regular use, seek medical advice to explore other treatment options.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Hyalofemme?

Hyalofemme is generally very well tolerated, and most women experience no side effects at all. When side effects do occur, they are typically mild, localised, and short-lived.

  • Mild irritation or discomfort at the site of application
  • Temporary sensation of warmth or tingling after insertion
  • Slight increase in vaginal discharge immediately after use

These effects usually resolve within a short time after application and do not typically require you to stop using the product. If they persist beyond the first few uses, speak to your pharmacist.

What Are the Less Common Side Effects of Hyalofemme?

A small number of women may experience less common reactions, particularly if they have sensitive skin or a pre-existing skin condition affecting the vulval or vaginal area.

  • Transient burning or stinging sensation inside the vagina
  • Redness or swelling of the vulval area
  • Increased sensitivity or soreness that was not present before use

If any of these occur and do not settle quickly, discontinue use and consult your pharmacist or GP before continuing.

What Are the Serious Side Effects of Hyalofemme?

Serious side effects are rare with Hyalofemme, but an allergic reaction (hypersensitivity) is possible in women who are sensitive to sodium hyaluronate or any other ingredient in the formulation. Signs of a serious allergic reaction include:

  • Severe rash, hives, or widespread skin irritation
  • Swelling of the face, lips, or throat
  • Difficulty breathing
  • Severe vaginal pain or swelling

If you experience any of these symptoms, stop using Hyalofemme immediately and seek urgent medical attention. Do not attempt to continue use if you suspect an allergic reaction.

What Should You Do If You Experience Side Effects?

For mild side effects, you may simply wish to monitor the situation over the first few applications to see whether your body adjusts. Many women find that any initial sensitivity settles down with continued use. However, if side effects are persistent, worsening, or causing significant discomfort, stop using the product and speak to your pharmacist or GP.

You can also report suspected side effects or adverse reactions to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve the safety monitoring of all medicines and medical devices used in the UK.

Can Hyalofemme Interact With Other Medicines?

No significant drug interactions have been identified for Hyalofemme when used as directed. However, if you are using other vaginal preparations — such as antifungal pessaries, topical oestrogen creams, or other gels — you should allow adequate time between applications to avoid diluting the effectiveness of either product. Always inform your pharmacist of all products you are currently using, including over-the-counter items.

Women using latex condoms or diaphragms should note that Hyalofemme is not specifically formulated as a lubricant for use during intercourse, and its compatibility with barrier contraceptives should be confirmed with a pharmacist before use.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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