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Vagisan MoistCream 50g

Vagisan MoistCream 50g

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  • ✔️ Relieves vaginal dryness, itching, and vulval irritation effectively
  • ✔️ Hormone-free formula suitable for women of all ages
  • ✔️ Dual-use cream for internal vaginal and external vulval application
  • ✔️ Bioadhesive formula maintains moisture between applications
  • ✔️ Suitable for women who cannot use oestrogen-based treatments

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What Is Vagisan MoistCream — a Vaginal Dryness Cream?

 

Vaginal dryness is more common than many people realise. It affects women at various life stages — during the menopause, after childbirth, while breastfeeding, or as a result of certain medications. Vagisan MoistCream 50g is a vaginal dryness cream that works without hormones, making it a practical option for women who want effective relief without the need for a prescription or hormone-based therapy. You can find it alongside other women's health products at Cured Pharmacy.

The cream is designed for both internal vaginal use and external application to the vulval area. It helps restore moisture, reduce itching, and ease the discomfort that dryness can cause in everyday life — not just during intercourse. At £14.19 for a 50g tube, it offers a straightforward, accessible solution.

 

How Does Vagisan MoistCream Work to Relieve Dryness?

 

The cream uses a combination of polycarbophil and carbomer — two bioadhesive polymers that cling to the vaginal mucosa and lock in moisture. Unlike lubricants, which provide only temporary slipperiness, Vagisan MoistCream works over a longer period by replenishing the moisture balance of the tissue itself. Here is how it works:

  • Polycarbophil and carbomer bind to the vaginal epithelium, forming a hydrating film.
  • The film retains water at the tissue surface, mimicking natural vaginal secretions.
  • Regular use helps maintain a healthier moisture level between applications.
  • The cream is hormone-free, so it does not interfere with the body's hormonal balance.

Because it contains no oestrogen or other hormones, it is suitable for women who have had hormone-sensitive cancers or who simply prefer to avoid hormonal products.

 

Who Should Use Vagisan MoistCream and Is It Right for You?

 

This cream is suitable for a wide range of women. Whether your dryness is linked to the menopause, hormonal contraception, cancer treatment, or simply your natural physiology, Vagisan MoistCream may help. It is not a treatment for infections, so if you have unusual discharge, odour, or pain, speak to your GP before using it.

  • Women experiencing menopausal vaginal dryness or atrophy
  • Women who cannot use hormone-based treatments for medical reasons
  • Those experiencing dryness due to breastfeeding or postpartum hormonal changes
  • Women using hormonal contraception that causes vaginal dryness as a side effect

 

How Does Vagisan MoistCream Compare to Other Vaginal Moisturisers?

 

Feature Vagisan MoistCream Replens MD
Hormone-free Yes Yes
Application method Internal applicator or external use Internal applicator only
Frequency of use 2–3 times per week Every 3 days
Suitable for external vulval use Yes No

 

Is Vagisan MoistCream Suitable for Long-Term Use and How Should It Be Stored?

 

Yes — vaginal dryness cream like Vagisan MoistCream can be used on an ongoing basis as part of your regular intimate care routine. There is no evidence to suggest harm from long-term use in otherwise healthy women. If your symptoms change or worsen, always check in with your GP or pharmacist. You might also find it helpful to explore our range of personal lubricants for additional comfort during intercourse.

Store the tube below 25°C, away from direct sunlight. Do not freeze. Keep the cap tightly closed after each use and store out of reach of children. Once opened, use within the period indicated on the packaging.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Vagisan MoistCream 50g specifications
Treatment category Vaginal dryness / intimate moisturiser
Mechanism of action Bioadhesive polymers form a moisture-retaining film on vaginal mucosa
Effective for Vaginal dryness, vulval itching, irritation
Suitable for Adult women of all ages; hormone-free
Active ingredient Polycarbophil, Carbomer
Pack size 50g
UK classification General Sale / OTC
Drug class Vaginal moisturiser (non-hormonal)
Preparation Cream
Route of administration Vaginal / external vulval application

Specifications of Vagisan MoistCream 50g

 

What Is Vagisan MoistCream and What Is It Used For?

 

Vagisan MoistCream is a non-hormonal vaginal moisturiser used to relieve the symptoms of vaginal dryness. These symptoms can include itching, burning, soreness, and discomfort during intercourse. The cream is suitable for adult women of all ages and does not require a prescription. It is particularly useful for women going through the menopause, when falling oestrogen levels cause the vaginal tissue to become thinner and less well-lubricated — a condition sometimes called vaginal atrophy or genitourinary syndrome of menopause (GSM).

It can also be used by women experiencing dryness due to breastfeeding, cancer treatments such as chemotherapy or radiotherapy, or as a side effect of certain medications including some antidepressants and antihistamines. The cream addresses both internal vaginal dryness and external vulval discomfort, making it a versatile option within the broader category of creams and ointments for intimate health.

 

What Do You Need to Know Before Using Vagisan MoistCream?

 

Before using this cream, read the following carefully. Do not use Vagisan MoistCream if any of the following apply to you:

  • You are allergic to polycarbophil, carbomer, or any other ingredient listed on the packaging.
  • You have an active vaginal infection — treat the infection first before using a moisturiser.
  • You are under 18 years of age.
  • You have unexplained vaginal bleeding — seek medical advice before use.

Important warnings to be aware of:

  • Vagisan MoistCream is not compatible with latex condoms or diaphragms — it may weaken the latex and reduce contraceptive effectiveness.
  • It is not a treatment for vaginal infections such as thrush or bacterial vaginosis.
  • If symptoms do not improve after four weeks of regular use, consult your GP.
  • Avoid contact with eyes. If accidental contact occurs, rinse thoroughly with water.

No significant drug interactions have been identified for Vagisan MoistCream when used as directed. However, if you are using other vaginal preparations, allow adequate time between applications and speak to your pharmacist for guidance.

 

How Should You Use Vagisan MoistCream Correctly?

 

Always use Vagisan MoistCream exactly as described in the patient information leaflet or as advised by your pharmacist. The cream can be applied internally using the supplied applicator or externally to the vulval area.

  1. Wash your hands thoroughly before and after application.
  2. For internal use, attach the applicator to the tube and squeeze a small amount of cream into the applicator barrel.
  3. Lie on your back with your knees bent, gently insert the applicator into the vagina, and press the plunger to release the cream.
  4. For external use, apply a small amount of cream directly to the vulval area and gently massage in.
  5. Clean the applicator with warm water and mild soap after each use.
Indication Age Group Dose Frequency
Vaginal dryness (internal) Adult women Approx. 1–2g per application 2–3 times per week
Vulval dryness / irritation (external) Adult women Small amount as needed Daily or as required

 

What Are the Possible Side Effects of Vagisan MoistCream?

 

Like all medicines, Vagisan MoistCream can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the area of application.

Common side effects:

  • Mild burning or stinging sensation immediately after application
  • Temporary redness or irritation at the application site

Less common side effects:

  • Increased vaginal discharge
  • Localised swelling or discomfort
  • Allergic skin reaction (rash, itching, or hives) — stop use immediately if this occurs

If you experience a severe allergic reaction — including swelling of the face, lips, or throat, or difficulty breathing — seek emergency medical attention immediately. These reactions are rare but serious. You can also explore our thrush treatments if you suspect your symptoms may be related to a fungal infection rather than simple dryness.

 

How Should You Store Vagisan MoistCream Safely?

 

  • Store below 25°C in a cool, dry place.
  • Do not freeze or expose to direct sunlight or heat sources.
  • Keep the tube tightly closed when not in use.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the tube or carton.
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Vagisan MoistCream online in the UK?

You can buy Vagisan MoistCream 50g online from Cured Pharmacy for £14.19 without a prescription. It is available as an over-the-counter product and can be ordered discreetly to your door. Simply add it to your basket and select your preferred delivery option at checkout.

How does Vagisan MoistCream work in the body?

Vagisan MoistCream contains polycarbophil and carbomer, which are bioadhesive polymers that stick to the vaginal mucosa and form a moisture-retaining film. This film holds water against the tissue surface, restoring hydration in a way that mimics natural vaginal secretions. Because it contains no hormones, it works purely through physical moisturisation rather than any hormonal mechanism.

How do I use Vagisan MoistCream step by step?

Using Vagisan MoistCream is straightforward. Follow these steps:

  1. Wash your hands before and after use.
  2. Attach the applicator to the tube for internal use, or apply directly to the vulval area for external use.
  3. Insert the applicator gently and press the plunger to release the cream internally, or massage a small amount externally as needed.

Use two to three times per week for internal dryness, or daily externally as required.

Is Vagisan MoistCream safe to use during the menopause?

Yes, Vagisan MoistCream is well-suited to menopausal women and is hormone-free, making it appropriate for those who cannot or prefer not to use oestrogen-based treatments. Vaginal dryness is one of the most common symptoms of the menopause, and a non-hormonal vaginal dryness cream like this one can provide meaningful relief. Always speak to your GP if you are unsure which treatment is most appropriate for your situation.

Can I use Vagisan MoistCream with condoms?

Vagisan MoistCream is not compatible with latex condoms or diaphragms, as the cream can degrade latex and reduce contraceptive effectiveness. If you need to use contraception at the same time, opt for non-latex condom alternatives. Speak to your pharmacist or GP for advice on compatible contraceptive options.

What are the side effects of Vagisan MoistCream?

Side effects are uncommon but can include:

  • Mild burning or stinging after application
  • Temporary redness or irritation
  • Rarely, an allergic skin reaction

If you experience a severe allergic reaction such as swelling, difficulty breathing, or widespread rash, stop use immediately and seek medical attention. Most women tolerate the cream well with regular use.

How long can I use Vagisan MoistCream for?

Vagisan MoistCream can be used on a long-term basis as part of your regular intimate care routine, as there is no evidence of harm from ongoing use in otherwise healthy adult women. If your symptoms do not improve after four weeks of regular use, consult your GP or pharmacist. There is no fixed maximum duration for use.

What are the alternatives to Vagisan MoistCream?

Alternatives include other non-hormonal vaginal moisturisers such as Replens MD or YES VM, as well as hormone-based treatments like topical oestrogen cream or pessaries available on prescription. You can also browse our range of personal lubricants for short-term relief during intercourse. Speak to your GP to find the most suitable option for your individual needs.

Is Vagisan MoistCream suitable for women who have had breast cancer?

Because Vagisan MoistCream is hormone-free, it is generally considered suitable for women who have had hormone-sensitive cancers such as breast cancer and cannot use oestrogen-based treatments. However, you should always discuss any new product with your oncologist or GP before starting use, particularly if you are currently undergoing treatment. Your medical team is best placed to advise on what is safe for your specific situation.

Can I use Vagisan MoistCream if I am pregnant or breastfeeding?

Vaginal dryness can occur during breastfeeding due to low oestrogen levels, and Vagisan MoistCream is hormone-free, which makes it a consideration for this group. However, if you are pregnant or breastfeeding, you should speak to your midwife, GP, or pharmacist before using any new product. They can confirm whether it is appropriate for your stage of pregnancy or postpartum recovery.

How quickly does Vagisan MoistCream start to work?

Many women notice some relief from dryness and irritation after the first few applications. However, the full moisturising benefit tends to build up with regular use over one to two weeks. Consistency is key — using the cream two to three times per week as directed gives the best results over time.

What happens if I miss an application of Vagisan MoistCream?

If you forget to apply Vagisan MoistCream, simply use it as soon as you remember and then continue with your usual schedule. Do not apply a double amount to make up for a missed application. Because this is a moisturiser rather than a medicine with a strict dosing schedule, occasional missed applications are unlikely to cause any harm.

Is Vagisan MoistCream the same as a personal lubricant?

No — Vagisan MoistCream is a vaginal moisturiser designed for regular use to maintain tissue hydration over time, whereas personal lubricants are intended for short-term use during sexual activity. The two products serve different purposes, though they can complement each other. You can explore our personal lubricants collection if you need additional support during intercourse.

What does the latest research say about non-hormonal vaginal moisturisers?

Clinical evidence supports the use of non-hormonal vaginal moisturisers as an effective first-line option for managing vaginal dryness, particularly in women who cannot use oestrogen therapy. Studies have shown that polycarbophil-based products can significantly reduce dryness, itching, and discomfort with regular use. The NHS and NICE both recognise non-hormonal moisturisers as a valid treatment option for genitourinary symptoms of menopause.

Can younger women use Vagisan MoistCream?

Yes — vaginal dryness is not exclusive to menopausal women. Younger women may experience dryness due to hormonal contraception, stress, certain medications, or autoimmune conditions. Vagisan MoistCream is suitable for adult women of all ages, provided there is no underlying infection or unexplained symptom that needs medical investigation first. If you are unsure about the cause of your symptoms, speak to your GP before starting any treatment.

How Should You Use Vagisan MoistCream?

Vagisan MoistCream can be applied internally using the supplied applicator or directly to the external vulval area. Always wash your hands thoroughly before and after use to maintain hygiene and reduce the risk of introducing bacteria.

What Is the Correct Dose of Vagisan MoistCream?

The dose varies depending on whether you are using the cream internally or externally. Do not apply more than the recommended amount, as this will not increase effectiveness and may cause unnecessary irritation.

When Is the Best Time to Use Vagisan MoistCream?

Many women find it most convenient to apply Vagisan MoistCream at bedtime. Applying it in the evening allows the cream to remain in contact with the vaginal tissue for longer without being disturbed by movement or clothing, which may improve its moisturising effect. There is no strict requirement to use it at a specific time of day, so choose a time that fits naturally into your routine and that you are likely to maintain consistently.

How Long Can You Use Vagisan MoistCream For?

Vagisan MoistCream is suitable for ongoing use as a regular part of your intimate care routine. Unlike some treatments, there is no defined maximum treatment period for otherwise healthy adult women. However, if your symptoms have not improved after four weeks of consistent use, or if they worsen at any point, you should consult your GP or pharmacist to rule out an underlying condition that may need a different approach.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Vagisan MoistCream?

Most women tolerate Vagisan MoistCream well, and side effects are generally mild and short-lived. The most commonly reported effects are localised to the area of application and tend to resolve on their own without any treatment.

  • Mild burning or stinging sensation immediately after application
  • Temporary redness at the application site
  • Slight irritation of the vaginal or vulval tissue

What Are the Less Common Side Effects of Vagisan MoistCream?

Less commonly, some women may notice other localised reactions. These are not typical but are worth being aware of before you start using the cream.

  • Increased vaginal discharge shortly after internal application
  • Localised swelling or a feeling of pressure in the vaginal area
  • Skin rash, itching, or hives around the vulval area

If any of these less common effects persist or become bothersome, stop using the cream and speak to your pharmacist or GP.

What Are the Serious Side Effects of Vagisan MoistCream?

Serious side effects are rare but can occur. A severe allergic reaction (anaphylaxis) is possible with any topical product, though it is extremely uncommon with Vagisan MoistCream. Signs of a serious allergic reaction include swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, a widespread skin rash, or a sudden drop in blood pressure causing dizziness or collapse. If you experience any of these symptoms, stop using the cream immediately and call 999 or go to your nearest A&E department.

What Should You Do If You Experience Side Effects of Vagisan MoistCream?

For mild side effects such as temporary stinging or redness, you may simply continue use and monitor whether the reaction settles after a few applications. If irritation persists beyond a few days or worsens, discontinue use and seek advice from your pharmacist. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk — this helps improve the safety monitoring of all medicines available in the UK.

Can Vagisan MoistCream Interact With Other Medicines?

No significant drug interactions have been identified for Vagisan MoistCream when used as directed. However, it is important to note that the cream is not compatible with latex condoms or diaphragms, as it can weaken the latex material and reduce their effectiveness as contraceptives. If you are using other vaginal preparations at the same time — such as antifungal creams or pessaries — allow sufficient time between applications and ask your pharmacist whether it is safe to use both products together.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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