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Treclin (Tretinoin) Gel

Treclin (Tretinoin) Gel

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Product Description

Treclin 1% / 0.025% w/w Gel is a prescription acne treatment that combines both clindamycin (1%) and tretinoin (0.025%). Clindamycin is an antibiotic that works in stopping the growth of acne-causing bacteria on the skin, reducing inflammation. Tretinoin is a type of retinoid that causes skin cells to turn over, helping unclog pores, shrinking blackheads and whiteheads, and smoothing the overall texture of your skin. 

When used in combination as Treclin Gel, they not only kill the bacteria that cause acne, but also help to prevent new spots from developing. Regular use of Treclin can also reduce the appearance of post-acne marks and help to leave skin looking clearer and smoother.

Treclin Gel should be used once daily in the evening, or as directed by your pharmacist. Some people might see improvement after a few weeks, but the best results are usually achieved after 8-12 weeks.

Direction For Use

Firstly, always use the treatment as prescribed by your pharmacist. Here are the 3 steps to use Treclin Gel Solution.  

1. Start by washing the affected skin area with a gentle cleanser, then pat dry.  

2. After the skin is completely dry, apply a thin layer of the solution to areas that are affected, usually once or twice a day. Consult your pharmacist for your personal daily dose.  

3. Wash your hands after application.  

Do not apply to sensitive areas like the mouth, eyes, broken, sunburned, or irritated skin. If your skin becomes dry or irritated, you may need to use the solution less often.

Side Effect

Like all medicines, Treclin Gel can cause side effects, although not everybody gets them. Most side effects are mild and affect the skin where the gel is applied.

Very common (may affect more than 1 in 10 people):

· Dry skin

· Redness

· Peeling

· Burning sensation

Common (may affect up to 1 in 10 people):

· Itching (pruritus)

· Increased skin sensitivity or tenderness

· Worsening of acne at the beginning of treatment

Uncommon (may affect up to 1 in 100 people):

· Skin irritation or rash

· Sunburn due to increased skin sensitivity to sunlight

· Oiliness of the skin

Rare but serious:

· Severe diarrhoea or stomach pain (could be a sign of antibiotic-associated colitis)

· Severe allergic reaction

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2088658
Muzammil Peerally

Authored by:

Muzammil Peerally

Superintendent Pharmacist

GPhC Number: 2232689
Tarun Kumar

Reviewed by:

Tarun Kumar

Clinical Leads

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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Comparison of Weight Loss Injectables

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Active Ingredient Tirzepatide Semaglutide Liraglutide
Mechanism of Action GLP-1 and GIP receptor agonist GLP-1 receptor agonist GLP-1 receptor agonist
Administration Weekly injection Weekly injection Daily injection
Dosage Varies by patient, typically starting low Varies, typically starting at 0.25 mg Varies, starting at 0.6 mg
Effect on Appetite Significantly reduces appetite and cravings Reduces appetite and increases satiety Reduces appetite and increases satiety
Average Weight Loss Up to 20% body weight reduction Up to 15% body weight reduction Significant weight reduction
Side Effects Nausea, vomiting, diarrhoea, constipation Nausea, vomiting, diarrhoea, constipation Nausea, diarrhoea, constipation, hypoglycemia
Approval FDA-approved for weight loss FDA-approved for weight loss FDA-approved for weight loss
Suitable For Adults with BMI ≥30 or ≥27 with comorbidities Adults with BMI ≥30 or ≥27 with comorbidities Adults with BMI ≥30 or ≥27 with comorbidities