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Piriton Hayfever & Allergy Tablets - 30 Tablets

Piriton Hayfever & Allergy Tablets - 30 Tablets

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  • ✔️ Relieves hayfever, hives, and allergic skin reactions fast
  • ✔️ Contains 4mg chlorphenamine maleate per tablet
  • ✔️ Starts working within approximately 30 minutes of taking
  • ✔️ Suitable for adults and children aged 6 years and over
  • ✔️ 30-tablet pack provides sustained allergy symptom control

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Are Chlorphenamine Tablets Right for Your Allergy?

 

Hayfever season can feel relentless — itchy eyes, a streaming nose, and that constant urge to sneeze. Piriton Hayfever & Allergy Tablets have been a trusted name in UK allergy relief for decades, and for good reason. Each tablet contains 4mg of chlorphenamine tablets' active ingredient, chlorphenamine maleate, a first-generation antihistamine licensed by the MHRA for the relief of allergic conditions. Whether your symptoms flare up in spring or you're reacting to a pet, these tablets offer fast-acting relief you can rely on. You can browse the full range of options in our allergy and hay fever collection if you'd like to compare products before deciding.

Piriton is one of the most widely recognised antihistamine brands in the UK, and the 30-tablet pack at £6.49 makes it an accessible, cost-effective choice for managing seasonal and perennial allergic symptoms.

 

How Do Piriton Hayfever & Allergy Tablets Work?

 

When your body encounters an allergen — pollen, dust mites, animal dander — it releases a chemical called histamine. Histamine binds to H1 receptors throughout the body, triggering the familiar cascade of sneezing, itching, watery eyes, and nasal congestion. Piriton works by competitively blocking those H1 receptors, stopping histamine from doing its job.

  • Chlorphenamine maleate binds to peripheral H1 histamine receptors
  • Receptor blockade prevents histamine-mediated inflammatory responses
  • As a first-generation antihistamine, it also crosses the blood-brain barrier, which accounts for its sedative effect
  • Onset of action is typically within 30 minutes of an oral dose
  • Duration of effect is approximately four to six hours per tablet

 

Who Should Use Piriton Hayfever & Allergy Tablets?

 

Piriton is suitable for a broad range of people dealing with allergic conditions. It's particularly useful when you need relief quickly and aren't concerned about the sedative effect — or when that sedative quality is actually welcome, such as when itching is disrupting your sleep.

  • Adults and children aged 6 years and over
  • People with seasonal allergic rhinitis (hayfever)
  • Those experiencing urticaria (hives) or skin rashes caused by allergies
  • Individuals reacting to insect bites or stings
  • People with food allergies causing mild skin or nasal symptoms (not anaphylaxis)

It is not suitable for children under 6, and caution is needed in older adults due to the increased risk of sedation and anticholinergic effects. Always read the label carefully.

 

How Do Piriton Tablets Compare to Non-Drowsy Antihistamines?

 

Feature Piriton (Chlorphenamine 4mg) Cetirizine 10mg (e.g. Zirtek)
Generation First-generation antihistamine Second-generation antihistamine
Drowsiness Common side effect Less likely to cause drowsiness
Dosing frequency Every 4–6 hours (up to 6 tablets/day) Once daily
Suitable age 6 years and over 6 years and over
OTC availability Yes Yes

 

How Should You Store Piriton Tablets and Who Should Avoid Them?

 

Store Piriton tablets below 25°C in a dry place, away from direct sunlight, and always out of the reach and sight of children. Do not use after the expiry date printed on the packaging. If you're unsure whether chlorphenamine tablets are right for you — particularly if you have epilepsy, glaucoma, an enlarged prostate, or liver problems — speak to your pharmacist or GP before use. Pregnant or breastfeeding women should also seek medical advice first, as the NHS advises caution with antihistamines during pregnancy.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Piriton Hayfever & Allergy Tablets - 30 Tablets specifications
Treatment category Allergy & Hayfever Relief
Active ingredient Chlorphenamine maleate 4mg
Mechanism of action H1 histamine receptor antagonist
Drug class First-generation antihistamine
Route of administration Oral
Preparation Tablet
Strengths 4mg
Pack sizes 30 tablets
UK classification General Sale List (GSL)
Suitable for Adults and children aged 6 years and over
Effective for Hayfever, allergic rhinitis, urticaria, insect bites, food allergy symptoms

Specifications of Piriton Hayfever & Allergy Tablets - 30 Tablets

 

What Is Piriton and What Is It Used For?

 

Piriton Hayfever & Allergy Tablets contain chlorphenamine maleate 4mg as the active ingredient. Chlorphenamine is a first-generation antihistamine used to relieve the symptoms of a wide range of allergic conditions. The NHS lists antihistamines as a first-line treatment for hayfever and other allergic reactions, and chlorphenamine has been used clinically in the UK for many years.

Piriton tablets are indicated for:

  • Seasonal and perennial allergic rhinitis (hayfever and dust mite allergy)
  • Urticaria (hives) and allergic skin rashes
  • Insect bite and sting reactions
  • Reactions to food or drug allergies causing skin or nasal symptoms
  • Symptomatic relief of itching associated with chickenpox (under medical guidance)

 

What Do You Need to Know Before Using Piriton Tablets?

 

Before taking Piriton, it's important to check whether it's appropriate for you. There are certain conditions and medicines that may make it unsuitable or require extra care.

Do not take Piriton if you:

  • Are allergic to chlorphenamine maleate or any other ingredient in the tablet
  • Are taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days
  • Are under 6 years of age
  • Have acute asthma or a lower respiratory tract infection where secretions need to remain fluid

Use with caution if you have:

  • Epilepsy or a history of seizures
  • Glaucoma (raised pressure in the eye)
  • An enlarged prostate or difficulty passing urine
  • Liver or kidney impairment
  • Cardiovascular disease or hypertension

Known drug interactions:

  • MAOIs — risk of serious hypertensive crisis; do not combine
  • Tricyclic antidepressants — increased anticholinergic effects
  • Sedatives, hypnotics, or anxiolytics — enhanced CNS depression
  • Alcohol — significantly increases drowsiness; avoid
  • Other antihistamines — additive sedative and anticholinergic effects

Pregnant or breastfeeding women should consult a GP or pharmacist before use. The NHS advises that most antihistamines are not recommended during pregnancy unless clearly necessary.

 

How Should You Use Piriton Hayfever & Allergy Tablets?

 

Always take Piriton exactly as described in the patient information leaflet or as directed by your pharmacist. Swallow the tablet whole with water. You can take it with or without food, though taking it with food may help if you experience any stomach discomfort.

  1. Read the patient information leaflet before taking your first dose
  2. Take one tablet with a full glass of water
  3. Repeat every four to six hours as needed
  4. Do not exceed the maximum daily dose for your age group
  5. If symptoms persist beyond 7 days, consult your GP
Age Group Dose Frequency Maximum Daily Dose
Adults & children 12+ 1 tablet (4mg) Every 4–6 hours 6 tablets (24mg)
Children 6–11 years ½ tablet (2mg) Every 4–6 hours 3 tablets (12mg)
Children under 6 Not recommended

If you're managing multiple allergy symptoms at once — for example, itchy eyes alongside nasal congestion — you might also find it helpful to explore our eye care range for targeted relief alongside your Piriton tablets.

 

What Are the Possible Side Effects of Piriton Tablets?

 

Like all medicines, Piriton can cause side effects, although not everyone experiences them. Because chlorphenamine is a first-generation antihistamine, it crosses the blood-brain barrier more readily than newer antihistamines, which is why drowsiness is particularly associated with this medicine.

Common side effects:

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Dizziness or impaired coordination
  • Headache
  • Blurred vision
  • Difficulty passing urine

Less common side effects:

  • Nausea or stomach upset
  • Palpitations or tachycardia
  • Skin rashes or photosensitivity
  • Paradoxical excitability (particularly in children)
  • Confusion or disorientation (more common in elderly patients)

Stop taking Piriton and seek immediate medical attention if you experience signs of a serious allergic reaction, such as swelling of the face, lips, or throat, or difficulty breathing.

 

How Should You Store Piriton Hayfever & Allergy Tablets?

 

Correct storage helps maintain the effectiveness and safety of your tablets. If you're also managing skin-related allergy symptoms, our skin care range includes topical options that complement oral antihistamine treatment.

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and moisture
  • Store in the original packaging to protect from light
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the carton
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Piriton Hayfever & Allergy Tablets online in the UK?

You can buy Piriton Hayfever & Allergy Tablets directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for £6.49 per 30-tablet pack. They are dispatched quickly and no prescription is required, as Piriton is a General Sale List medicine. You can also browse our full allergy and hay fever collection for additional options.

How do Piriton tablets work in the body?

Piriton tablets contain chlorphenamine maleate, which works by blocking H1 histamine receptors throughout the body. When an allergen triggers histamine release, chlorphenamine prevents histamine from binding to those receptors, stopping the chain reaction that causes sneezing, itching, and a runny nose. Because it's a first-generation antihistamine, it also crosses the blood-brain barrier, which is why it can cause drowsiness.

How do I take Piriton tablets step by step?

Adults and children aged 12 and over should take one 4mg tablet with a full glass of water, every four to six hours as needed. You can take it with or without food. Never exceed six tablets in any 24-hour period, and if symptoms haven't improved after seven days, speak to your GP.

What is the correct dose of Piriton for adults and children?

Adults and children aged 12 and over take one tablet (4mg) every four to six hours, up to a maximum of six tablets per day. Children aged 6 to 11 years take half a tablet (2mg) every four to six hours, up to a maximum of three tablets per day. Piriton tablets are not suitable for children under 6 years of age.

When is the best time to take Piriton tablets?

Because Piriton can cause drowsiness, many people find it most useful in the evening when sedation is less of a concern — or when itching is disrupting sleep. If you need daytime relief, be aware of the drowsiness risk and avoid driving or operating machinery. Taking it around 30 minutes before anticipated allergen exposure can also help prevent symptoms from starting.

Can Piriton tablets cause drowsiness?

Yes — drowsiness is one of the most common side effects of Piriton because chlorphenamine crosses the blood-brain barrier. The NHS advises that you should not drive, cycle, or operate heavy machinery if you feel drowsy after taking it. Alcohol significantly worsens this effect, so avoid drinking alcohol while taking Piriton.

How do I manage side effects of Piriton tablets?

If drowsiness is a problem, try taking Piriton in the evening rather than during the day, or consider switching to a non-drowsy antihistamine such as cetirizine or loratadine. For dry mouth, sipping water regularly can help. If you experience any unusual or severe side effects, stop taking the tablets and contact your pharmacist or GP promptly.

Who is eligible to take Piriton Hayfever & Allergy Tablets?

Piriton tablets are suitable for adults and children aged 6 years and over who are experiencing symptoms of hayfever, allergic rhinitis, urticaria, or other allergic conditions. They are not suitable for children under 6, people taking MAOIs, or those with certain conditions such as acute asthma or narrow-angle glaucoma. Always check the patient information leaflet or speak to a pharmacist if you're unsure.

What happens if I miss a dose of Piriton?

If you miss a dose, simply take the next one when needed — but make sure at least four hours have passed since your last tablet. Do not double up to make up for a missed dose. Piriton is taken as needed rather than on a strict schedule, so missing a dose is generally not a concern as long as you don't exceed the daily maximum.

What are the alternatives to Piriton tablets for hayfever?

If you'd prefer a non-drowsy option, second-generation antihistamines such as cetirizine (Zirtek) or loratadine (Clarityn) are widely available and only need to be taken once daily. Nasal corticosteroid sprays such as beclometasone are also recommended by the NHS for persistent hayfever symptoms. You can explore the full range in our allergy and hay fever collection.

Can I take Piriton tablets with other medicines?

Piriton interacts with several medicines, including MAOIs, tricyclic antidepressants, sedatives, and other antihistamines — all of which can increase the risk of side effects. Alcohol also significantly enhances the sedative effect. Always tell your pharmacist about any other medicines you are taking before starting Piriton.

Is Piriton safe to take during pregnancy or breastfeeding?

The NHS advises that antihistamines are generally not recommended during pregnancy unless clearly necessary, and you should always consult your GP or midwife before taking any medicine while pregnant. Chlorphenamine may pass into breast milk, so breastfeeding women should also seek medical advice before use. Your doctor can help you weigh up the risks and benefits.

How long can you take Piriton tablets for?

Piriton can be used for short-term relief of allergy symptoms, typically for the duration of your exposure to the allergen — for example, throughout hayfever season. If you find you need to take it continuously for more than a few weeks, it's worth speaking to your GP to review your allergy management plan. Long-term daily use should be discussed with a healthcare professional.

What are the latest findings on chlorphenamine for allergy relief?

Chlorphenamine remains a well-established, clinically recognised antihistamine that has been used in the UK for decades. Current NHS and NICE guidance continues to recommend first-generation antihistamines like chlorphenamine for acute allergic reactions, while second-generation antihistamines are generally preferred for ongoing daily use due to their reduced sedative profile. No new safety concerns have emerged that change its OTC status in the UK.

Can Piriton tablets help with skin allergies and hives?

Yes — Piriton is licensed for the relief of urticaria (hives) and allergic skin rashes, as well as reactions to insect bites and stings. The NHS recommends antihistamines as a first-line treatment for urticaria to reduce itching and redness. If your skin symptoms are severe or persistent, a GP can advise on additional treatments — and you may also find our skin care range helpful for topical support.

How Should You Use Piriton Hayfever & Allergy Tablets?

Piriton tablets are taken orally with a full glass of water. You can take them with or without food, though if you notice any stomach discomfort, taking them with a light meal or snack may help.

What Is the Correct Dose of Piriton Hayfever & Allergy Tablets?

The dose varies depending on age. Always follow the dosage instructions in the patient information leaflet and never exceed the stated maximum daily dose. If you are unsure about the right dose for a child, speak to your pharmacist before administering.

When Is the Best Time to Use Piriton Hayfever & Allergy Tablets?

Because Piriton can cause drowsiness, many people find it most practical to take it in the evening — particularly if itching or nasal symptoms are disrupting sleep. If you need daytime relief, plan around activities that don't require full alertness, and avoid driving or operating machinery until you know how the tablets affect you. Taking a dose approximately 30 minutes before known allergen exposure (such as going outdoors during high pollen counts) can also help prevent symptoms from developing.

How Long Can You Use Piriton Hayfever & Allergy Tablets For?

Piriton is suitable for short-term use during periods of allergen exposure, such as the hayfever season. If you find you need to take it every day for more than a few weeks, it's advisable to speak to your GP to review your allergy management. Long-term continuous use should always be discussed with a healthcare professional to ensure it remains appropriate for your situation.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Piriton Tablets?

The most frequently reported side effect of Piriton is drowsiness. Because chlorphenamine maleate is a first-generation antihistamine, it crosses the blood-brain barrier more readily than newer antihistamines, producing a sedative effect in many people. This is worth bearing in mind if you need to drive, cycle, or concentrate at work.

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Dizziness or impaired coordination
  • Headache
  • Blurred vision

What Are the Less Common Side Effects of Piriton Tablets?

Some people experience side effects that are less frequent but still worth knowing about. These tend to be more common in older adults or in people taking higher doses. If any of the following persist or feel severe, stop taking the tablets and speak to your pharmacist or GP.

  • Nausea or stomach upset
  • Difficulty passing urine (urinary retention)
  • Palpitations or a faster-than-normal heartbeat
  • Skin rash or increased sensitivity to sunlight
  • Paradoxical excitability or restlessness, particularly in children
  • Confusion or disorientation, more common in elderly patients

What Are the Serious Side Effects of Piriton Tablets?

Serious side effects are rare but require immediate medical attention. Stop taking Piriton straight away and call 999 or go to your nearest A&E if you experience any of the following, as they may indicate a severe allergic reaction (anaphylaxis) or another serious problem.

  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin reactions such as blistering or peeling
  • Seizures or convulsions

What Should You Do If You Experience Side Effects of Piriton?

For mild side effects such as drowsiness or dry mouth, adjusting the timing of your dose — for example, taking it in the evening — can make a significant difference. Staying well hydrated helps with dry mouth. If side effects are affecting your daily life or don't improve, speak to your pharmacist, who may suggest switching to a non-drowsy antihistamine. You can report any suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Piriton Tablets Interact With Other Medicines?

Yes — Piriton has several clinically significant interactions. Taking it alongside monoamine oxidase inhibitors (MAOIs) is contraindicated due to the risk of serious adverse effects. Combining Piriton with tricyclic antidepressants, sedatives, sleeping tablets, or other antihistamines increases the risk of excessive sedation and anticholinergic effects. Alcohol also significantly enhances drowsiness and should be avoided while taking Piriton. Always inform your pharmacist of all medicines, supplements, and herbal remedies you are taking before starting Piriton.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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