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Pirinase Hayfever Nasal Spray - 60 Sprays

Pirinase Hayfever Nasal Spray - 60 Sprays

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  • ✔️ Targets nasal hay fever symptoms directly at the source
  • ✔️ Contains fluticasone propionate 50mcg per actuation
  • ✔️ Relieves sneezing, congestion, and runny nose effectively
  • ✔️ Suitable for adults aged 18 and over without a prescription
  • ✔️ 60 sprays provide a full hay fever season supply

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What Is Pirinase Hayfever Nasal Spray and Does It Work?

 

If hay fever leaves you sneezing, congested, and miserable every spring and summer, you are far from alone. Hay fever affects around one in five people in the UK, and finding a treatment that actually keeps symptoms under control can take some trial and error. Pirinase hayfever nasal spray is a well-established, pharmacy-available option that targets nasal symptoms directly at their source — without the drowsiness that antihistamine tablets can sometimes cause. Available from our allergy and hay fever range, this 60-spray pack offers a full season's supply for many users.

Each actuation delivers 50 micrograms of fluticasone propionate, a corticosteroid that works locally inside the nasal passages. It is licensed for over-the-counter sale to adults aged 18 and over in the UK, and it does not require a prescription when used as directed.

 

How Does Pirinase Hayfever Nasal Spray Work in the Body?

 

Fluticasone propionate belongs to a class of medicines called corticosteroids. When you spray it into your nose, it acts locally on the nasal lining to reduce the inflammatory response triggered by allergens like grass pollen, tree pollen, and house dust mites. Because it works at the site of inflammation rather than systemically, the risk of whole-body steroid side effects is very low at the recommended dose.

  • Allergen enters the nasal passages and triggers an immune response.
  • Mast cells release histamine and other inflammatory chemicals, causing swelling, itching, and excess mucus.
  • Fluticasone propionate binds to glucocorticoid receptors in nasal tissue and suppresses this inflammatory cascade.
  • Nasal congestion, sneezing, and a runny nose gradually reduce with regular daily use.
  • Full benefit is usually felt after several days of consistent use — it is not an instant-relief spray.

 

Who Should Use Pirinase Hayfever Nasal Spray?

 

This spray is suitable for adults aged 18 and over who experience seasonal allergic rhinitis — commonly known as hay fever. It is particularly useful if your main symptoms are nasal: congestion, sneezing, a runny or itchy nose. If you also suffer from itchy, watery eyes alongside your nasal symptoms, you might want to explore our eye care range for complementary relief options.

  • Adults aged 18 and over with seasonal hay fever symptoms.
  • People who find antihistamine tablets cause unwanted drowsiness.
  • Those who need daily, consistent nasal symptom control throughout the pollen season.
  • Individuals whose nasal congestion is the dominant and most troublesome symptom.

 

How Does Pirinase Compare to Other Hayfever Nasal Sprays?

 

Feature Pirinase Hayfever Nasal Spray Beconase Hayfever Nasal Spray
Active ingredient Fluticasone propionate 50mcg Beclometasone dipropionate 50mcg
Age suitability (OTC) 18 years and over 18 years and over
Onset of action Several days of regular use Several days of regular use
Sprays per pack 60 sprays 200 sprays

 

Is Pirinase Hayfever Nasal Spray Suitable for Long-Term Use?

 

For most adults, pirinase hayfever nasal spray is safe to use throughout the hay fever season. However, if you find yourself needing it for longer than three months continuously, it is worth speaking to your GP or pharmacist. They can review whether a prescription-strength option or a different treatment approach might be more appropriate for you.

Store the spray below 30°C and keep it away from direct sunlight. Do not freeze it. Always check the expiry date before use, and keep it out of reach of children. If you are also managing other seasonal conditions, our ear, nose and throat range includes additional products that may help.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Pirinase Hayfever Nasal Spray 60 Sprays specifications
Treatment category Allergic rhinitis / Hay fever
Active ingredient Fluticasone propionate 50 micrograms per actuation
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation locally
Drug class Corticosteroid (glucocorticoid)
Preparation Aqueous nasal spray suspension
Route of administration Intranasal
Pack size 60 sprays
Strengths 50 micrograms per actuation
UK classification Pharmacy (P) medicine
Suitable for Adults aged 18 and over
Effective for Seasonal allergic rhinitis (hay fever)

Specifications of Pirinase Hayfever Nasal Spray 60 Sprays

 

What Is Pirinase Hayfever Nasal Spray and What Is It Used For?

 

Pirinase Hayfever Nasal Spray contains fluticasone propionate 50 micrograms per actuation. It is used to relieve and prevent the nasal symptoms of seasonal allergic rhinitis — more commonly known as hay fever — in adults aged 18 and over. Symptoms it helps with include a blocked or runny nose, sneezing, and nasal itching caused by exposure to pollen and other airborne allergens. It is a Pharmacy (P) medicine available without a prescription from a registered UK pharmacy.

 

What Do You Need to Know Before Using Pirinase Hayfever Nasal Spray?

 

Do not use this spray if any of the following apply to you:

  • You are under 18 years of age (OTC use is not licensed for under-18s).
  • You have a current nasal infection — treat the infection first before starting this spray.
  • You have recently had nasal surgery or a nasal injury — wait until healing is complete.
  • You are allergic to fluticasone propionate or any other ingredient in the formulation.
  • You are pregnant or breastfeeding — seek medical advice before use.

The following medicines may interact with fluticasone propionate. Tell your pharmacist or GP if you are taking:

  • Ritonavir (used to treat HIV) — may significantly increase fluticasone levels in the blood.
  • Ketoconazole or other strong CYP3A4 inhibitors — may increase systemic exposure to fluticasone.
  • Other corticosteroid medicines (inhaled, oral, or topical) — combined use increases the risk of systemic steroid effects.

 

How Should You Use Pirinase Hayfever Nasal Spray Correctly?

 

  1. Blow your nose gently to clear the nasal passages before use.
  2. Shake the bottle well before each use.
  3. Remove the protective cap from the nozzle.
  4. Tilt your head slightly forward — do not tilt it back.
  5. Close one nostril with a finger and gently insert the nozzle into the open nostril.
  6. Press the pump firmly once while breathing in slowly through your nose.
  7. Breathe out through your mouth.
  8. Repeat in the other nostril.
  9. Wipe the nozzle clean and replace the cap after use.
Indication Age Group Dose Frequency
Hay fever (starting dose) Adults 18+ 2 sprays per nostril (200mcg total) Once daily
Hay fever (maintenance) Adults 18+ 1 spray per nostril (100mcg total) Once daily
Under 18 years Not applicable (OTC) Not recommended OTC

 

What Are the Possible Side Effects of Pirinase Hayfever Nasal Spray?

 

Like all medicines, this spray can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nose.

Common side effects (may affect up to 1 in 10 people):

  • Nosebleeds (epistaxis)
  • Nasal dryness or irritation
  • Unpleasant taste or smell

Less common side effects (may affect up to 1 in 100 people):

  • Nasal ulceration or crusting
  • Headache
  • Throat irritation
  • Raised intraocular pressure (rare with long-term use)
  • Perforation of the nasal septum (very rare — usually associated with incorrect technique)

If you experience any signs of an allergic reaction — such as a rash, swelling of the face or throat, or difficulty breathing — stop using the spray immediately and seek urgent medical attention. You can also browse our allergy and hay fever range for alternative treatment options if this spray is not suitable for you.

 

How Should You Store Pirinase Hayfever Nasal Spray Safely?

 

  • Store below 30°C.
  • Do not freeze the spray — freezing can damage the pump mechanism.
  • Keep away from direct sunlight and heat sources.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the label.
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy for safe disposal.

If you are managing multiple seasonal symptoms alongside hay fever, our cold and flu range includes products that may help distinguish and treat overlapping nasal symptoms during winter months.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Pirinase Hayfever Nasal Spray online in the UK?

You can buy Pirinase Hayfever Nasal Spray directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £8.20 per 60-spray pack. No prescription is needed for adults aged 18 and over. Simply add it to your basket alongside any other products from our allergy and hay fever range and proceed to checkout.

How does Pirinase Hayfever Nasal Spray work in the body?

Pirinase contains fluticasone propionate, a corticosteroid that reduces inflammation in the nasal lining caused by allergens such as grass or tree pollen. It works locally inside the nose rather than being absorbed into the bloodstream in significant amounts, which keeps systemic side effects to a minimum. Regular daily use builds up its anti-inflammatory effect over several days, providing sustained symptom relief throughout the hay fever season.

How do I use Pirinase Hayfever Nasal Spray step by step?

Blow your nose gently first, then shake the bottle and remove the cap. Tilt your head slightly forward, insert the nozzle into one nostril while closing the other, and press the pump once while breathing in slowly through your nose. Repeat in the other nostril, then wipe the nozzle and replace the cap. Avoid pointing the nozzle directly at the nasal septum — aim slightly outward towards the side of the nostril to reduce the risk of irritation.

What is the correct dose of Pirinase Hayfever Nasal Spray for adults?

The recommended starting dose for adults aged 18 and over is two sprays into each nostril once daily, giving a total daily dose of 200 micrograms of fluticasone propionate. Once your symptoms are well controlled, you can reduce to one spray per nostril once daily as a maintenance dose. Never exceed two sprays per nostril per day, and always use the lowest effective dose.

When is the best time to use Pirinase Hayfever Nasal Spray each day?

Most people find it easiest to use Pirinase in the morning, ideally before going outside and before pollen exposure begins. Consistency matters more than the exact time of day — using it at the same time each day helps maintain a steady anti-inflammatory effect in the nasal passages. If you forget a dose, simply use it as soon as you remember and then continue your usual routine the following day.

What are the common side effects of Pirinase Hayfever Nasal Spray?

The most frequently reported side effects are nosebleeds, nasal dryness, and a mild unpleasant taste or smell after use. These are generally mild and often improve as your nose adjusts to the spray over the first week or two. If nosebleeds are persistent or heavy, stop using the spray and speak to your pharmacist or GP.

How do I manage side effects of Pirinase Hayfever Nasal Spray?

To reduce the risk of nosebleeds, make sure you are using the correct technique — aim the nozzle away from the nasal septum and do not sniff hard after spraying. Nasal dryness can sometimes be eased by using a saline nasal rinse before applying the spray. If side effects persist or feel severe, contact your pharmacist for personalised advice before stopping treatment abruptly.

Who is eligible to use Pirinase Hayfever Nasal Spray without a prescription?

Pirinase is licensed for OTC use in adults aged 18 and over who have seasonal allergic rhinitis (hay fever). It is not suitable for children under 18 when purchased over the counter — a GP can prescribe fluticasone nasal spray for younger patients if clinically appropriate. People with nasal infections, recent nasal surgery, or certain medical conditions should seek advice from a healthcare professional before use.

Can I use Pirinase Hayfever Nasal Spray during pregnancy?

If you are pregnant or breastfeeding, you should not use Pirinase without first speaking to your GP or midwife. While intranasal fluticasone has low systemic absorption, it is not licensed OTC for use during pregnancy, and a healthcare professional needs to weigh up the potential benefits and risks for your individual situation. There may be safer alternatives your doctor can recommend.

What happens if I miss a dose of Pirinase Hayfever Nasal Spray?

If you miss a dose, use it as soon as you remember — unless it is almost time for your next scheduled dose, in which case simply skip the missed one. Do not use a double dose to make up for a missed one. Missing the occasional dose is unlikely to cause a significant problem, but consistent daily use gives the best symptom control over the hay fever season.

How long can you use Pirinase Hayfever Nasal Spray for?

Pirinase can be used throughout the hay fever season, which in the UK typically runs from late March to September depending on which pollens trigger your symptoms. If you find you need to use it for longer than three months continuously, it is advisable to speak to your GP or pharmacist for a review. Long-term use without medical oversight is not recommended.

How does Pirinase compare to Beconase for hay fever?

Both Pirinase (fluticasone propionate) and Beconase (beclometasone dipropionate) are intranasal corticosteroids available OTC for hay fever in adults. Fluticasone propionate has a higher receptor binding affinity than beclometasone, meaning it may provide effective relief at a lower microgram dose. Both are considered safe and effective for seasonal allergic rhinitis when used as directed, and the choice often comes down to personal preference and tolerability.

Can I use Pirinase Hayfever Nasal Spray with antihistamine tablets?

Yes, using a nasal corticosteroid spray alongside an oral antihistamine is a common and clinically accepted approach for managing hay fever, particularly when both nasal and eye symptoms are present. There is no known direct pharmacokinetic interaction between fluticasone nasal spray and standard antihistamines such as cetirizine or loratadine. Always let your pharmacist know all the medicines you are taking so they can check for any potential interactions.

What are the alternatives to Pirinase Hayfever Nasal Spray?

Alternatives include other intranasal corticosteroids such as Beconase (beclometasone) or Nasacort (triamcinolone), as well as oral antihistamines like cetirizine or loratadine for broader symptom relief. If your hay fever also causes itchy, watery eyes, you might find products from our eye care range helpful alongside your nasal spray. Your pharmacist can help you choose the most appropriate combination based on your specific symptoms.

What are the latest findings on fluticasone nasal spray for hay fever?

Intranasal corticosteroids, including fluticasone propionate, remain the first-line recommended treatment for moderate-to-severe allergic rhinitis according to current NHS and NICE guidance. Clinical evidence consistently shows they are more effective than antihistamines alone for nasal congestion. Research continues to support their favourable safety profile when used at recommended doses, with minimal systemic absorption at standard intranasal doses in adults.

How Should You Use Pirinase Hayfever Nasal Spray?

Using Pirinase correctly makes a real difference to how well it works. Before you start, blow your nose gently to clear the nasal passages. Always shake the bottle before each use to ensure the suspension is evenly mixed.

What Is the Correct Dose of Pirinase Hayfever Nasal Spray?

The dose depends on whether you are starting treatment or maintaining control of your symptoms. Always use the lowest effective dose once your symptoms are under control, and never exceed the maximum recommended daily dose.

When Is the Best Time to Use Pirinase Hayfever Nasal Spray?

Most people find that using Pirinase in the morning works best, ideally before heading outside and before pollen exposure begins for the day. Consistency is key — using it at the same time each day helps maintain a steady anti-inflammatory effect in the nasal passages, which is more effective than using it only when symptoms flare up.

If you are starting treatment at the beginning of the hay fever season, begin using the spray a few days before you expect your symptoms to start. This gives the fluticasone time to build up its protective effect in the nasal lining before allergen exposure peaks.

How Long Can You Use Pirinase Hayfever Nasal Spray For?

Pirinase is suitable for use throughout the hay fever season, which in the UK typically runs from late March through to September, depending on which pollens affect you most. For most adults, this means using it for several weeks to a few months each year without concern.

If you find you need to use it for longer than three months continuously, or if your symptoms are not adequately controlled, speak to your GP or pharmacist. They can review your treatment and advise whether a prescription-strength option or a different approach is more appropriate for your needs.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Pirinase Hayfever Nasal Spray?

Most people tolerate Pirinase well, but like all medicines it can cause side effects in some users. The most frequently reported ones are localised to the nose and are generally mild in nature. They often improve on their own after the first week or two of use as your nasal passages adjust.

  • Nosebleeds (epistaxis) — the most commonly reported side effect
  • Nasal dryness or irritation inside the nose
  • Unpleasant taste or smell following use
  • Mild nasal discomfort or stinging immediately after spraying

What Are the Less Common Side Effects of Pirinase Hayfever Nasal Spray?

Less common side effects occur in fewer users but are still worth being aware of. If you notice any of the following, mention them to your pharmacist at your next opportunity, particularly if they persist or worsen over time.

  • Nasal ulceration or crusting inside the nose
  • Headache
  • Throat irritation or dryness
  • Hoarseness of the voice
  • Raised intraocular pressure (with prolonged use — relevant if you have glaucoma)
  • Nasal septal perforation (very rare, usually linked to incorrect spray technique)

What Are the Serious Side Effects of Pirinase Hayfever Nasal Spray?

Serious side effects are rare when Pirinase is used at the recommended dose. However, you should be aware of the signs of an allergic reaction, which — though uncommon — can occur with any medicine. Seek emergency medical help immediately if you experience any of the following after using this spray.

  • Sudden rash, hives, or widespread skin redness
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Feeling faint or dizzy

With long-term use at higher-than-recommended doses, there is a theoretical risk of systemic corticosteroid effects such as adrenal suppression or reduced bone density. This is why using the lowest effective dose and not exceeding the recommended duration without medical review is important.

What Should You Do If You Experience Side Effects of Pirinase?

For mild side effects such as nasal dryness or occasional nosebleeds, adjusting your technique often helps. Make sure you are aiming the nozzle slightly outward — away from the nasal septum — and not sniffing hard after spraying. A saline nasal rinse used before applying the spray can also help reduce dryness and irritation.

If a nosebleed does not stop within 10–15 minutes, or if you experience any side effect that concerns you, stop using the spray and contact your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Pirinase Hayfever Nasal Spray Interact With Other Medicines?

Pirinase is generally safe to use alongside most common medicines, but there are some important interactions to be aware of. Ritonavir (used to treat HIV) and strong CYP3A4 inhibitors such as ketoconazole can significantly increase the amount of fluticasone absorbed into the bloodstream, raising the risk of systemic corticosteroid side effects. Using Pirinase alongside other corticosteroid medicines — whether inhaled, oral, or topical — may also increase this risk. Always tell your pharmacist or GP about all medicines, supplements, and herbal remedies you are taking before starting this spray.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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