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Pirinase Hay Fever Nasal Spray - 60 Doses

Pirinase Hay Fever Nasal Spray - 60 Doses

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  • ✔️ Targets nasal inflammation directly with fluticasone propionate 50 mcg
  • ✔️ Relieves sneezing, congestion, and nasal itching from hay fever
  • ✔️ Once-daily dosing for convenient, consistent symptom control
  • ✔️ Provides 60 doses — a full month's supply at standard adult dose
  • ✔️ Suitable for seasonal and year-round allergic rhinitis in adults

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Is Pirinase Hay Fever Nasal Spray Right for You?

 

Hay fever affects roughly one in five people in the UK, and for many, the sneezing, congestion, and itching can make spring and summer genuinely miserable. Pirinase hay fever nasal spray is a clinically established, over-the-counter option that targets the root cause of nasal symptoms — inflammation — rather than simply masking them. Available from our allergy and hay fever range, it offers a practical, once-daily solution for adults aged 18 and over.

Each actuation delivers 50 micrograms of fluticasone propionate directly into the nasal passages. With 60 doses per bottle, you get a full month's supply at the standard adult dose, making it a cost-effective choice for managing seasonal allergic rhinitis throughout the pollen season.

 

How Does Pirinase Nasal Spray Work in the Body?

 

Fluticasone propionate belongs to a class of medicines called corticosteroids. When you spray it into your nose, it acts locally on the nasal mucosa to reduce the inflammatory response triggered by allergens like grass pollen, tree pollen, and house dust mites. It does not enter the bloodstream in significant amounts at the recommended dose, which is why it is considered well-tolerated for regular use.

  • Allergen exposure triggers mast cells to release histamine and other inflammatory mediators
  • Fluticasone propionate binds to glucocorticoid receptors in nasal tissue
  • This suppresses the production of cytokines and other chemicals that cause swelling, mucus, and irritation
  • Symptoms — including sneezing, itching, and nasal blockage — gradually reduce with consistent daily use

It is worth noting that Pirinase does not work instantly. Most people notice an improvement after three to four days of regular use, so starting treatment a few days before peak pollen season is a sensible approach.

 

Who Is Pirinase Hay Fever Nasal Spray Suitable For?

 

This product is licensed for adults aged 18 and over for the relief of seasonal and perennial allergic rhinitis. It is particularly useful if antihistamine tablets alone are not controlling your nasal symptoms, or if you prefer a targeted nasal treatment over a systemic one.

  • Adults aged 18 and over with seasonal hay fever (allergic rhinitis)
  • People with year-round nasal allergy symptoms triggered by dust mites or pet dander
  • Those who have not found adequate relief from oral antihistamines alone
  • Individuals looking for a once-daily, non-drowsy nasal treatment

It is not suitable for children under 18 without medical supervision, and you should not use it if you have an active nasal infection or have recently had nasal surgery. Always read the label before use.

 

How Does Pirinase Compare to Other Hay Fever Nasal Sprays?

 

Feature Pirinase (Fluticasone propionate) Beconase (Beclometasone dipropionate)
Active ingredient Fluticasone propionate 50 mcg Beclometasone dipropionate 50 mcg
Dosing frequency Once daily (2 sprays per nostril) Twice daily (2 sprays per nostril)
Age suitability (OTC) 18 years and over 18 years and over
Onset of action 3–4 days of regular use 3–7 days of regular use

 

How Should You Store Pirinase Nasal Spray?

 

Store your Pirinase hay fever nasal spray below 30°C, away from direct sunlight and heat sources. Keep the bottle upright and do not freeze it. Once opened, the product should be used within the period indicated on the packaging — typically within 2 months. If you are also managing eye-related allergy symptoms alongside nasal ones, you may find our eye care range a helpful complement to your treatment.

Check the expiry date before use and keep the product out of reach of children, even though it is an adult-use product.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Pirinase Hay Fever Nasal Spray 60 Doses specifications
Treatment category Allergic rhinitis / Hay fever
Active ingredient Fluticasone propionate 50 micrograms per actuation
Mechanism of action Intranasal corticosteroid — reduces nasal inflammation
Drug class Corticosteroid
Preparation Aqueous nasal spray suspension
Route of administration Intranasal
Pack size 60 doses
Strength 50 mcg per actuation
UK classification Pharmacy (P) medicine
Suitable for Adults aged 18 and over
Effective for Seasonal and perennial allergic rhinitis

Specifications of Pirinase Hay Fever Nasal Spray 60 Doses

 

What Is Pirinase Nasal Spray and What Is It Used For?

 

Pirinase Hay Fever Nasal Spray contains fluticasone propionate 50 micrograms per actuation. It is used to treat the symptoms of seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults aged 18 and over. Symptoms it helps relieve include a blocked or runny nose, sneezing, nasal itching, and postnasal drip. It is a Pharmacy (P) medicine available without a prescription from registered UK pharmacies.

Unlike antihistamine tablets, which work systemically throughout the body, this spray acts directly in the nasal passages. That means it targets inflammation at the source, which is why many people find it more effective for nasal congestion specifically. If you are managing multiple allergy symptoms, you may also want to explore our broader allergy and hay fever collection for complementary treatments.

 

What Do You Need to Know Before Using Pirinase Nasal Spray?

 

Before using this product, read the following carefully. There are situations where Pirinase may not be appropriate, and some medicines can interact with fluticasone propionate.

Do not use Pirinase if you:

  • Are under 18 years of age (OTC use)
  • Have an active nasal or sinus infection
  • Have recently had nasal surgery or a nasal injury — wait until fully healed
  • Are allergic to fluticasone propionate or any other ingredient in the spray
  • Have tuberculosis (current or previously untreated)

Drug interactions — tell your pharmacist if you are taking:

  • Ritonavir or other strong CYP3A4 inhibitors (e.g. some HIV medicines, ketoconazole) — these can significantly increase fluticasone levels in the blood
  • Other corticosteroid medicines (inhaled, oral, or topical) — combined use may increase the risk of systemic corticosteroid effects

If you are pregnant or breastfeeding, speak to your GP or pharmacist before using this product. While systemic absorption is low at recommended doses, medical guidance is still advisable.

 

How Should You Use Pirinase Hay Fever Nasal Spray?

 

Using the spray correctly makes a real difference to how well it works. Follow these steps each time:

  1. Blow your nose gently to clear the nasal passages
  2. Shake the bottle gently before use
  3. Remove the dust cap and prime the pump if using for the first time (press down 6 times until a fine mist appears)
  4. Tilt your head slightly forward — do not tilt it back
  5. Insert the nozzle gently into one nostril, pointing it slightly away from the nasal septum
  6. Press the pump once while breathing in slowly through your nose
  7. Breathe out through your mouth
  8. Repeat in the other nostril
  9. Replace the dust cap after use and wipe the nozzle clean
Indication Age Group Dose Frequency
Seasonal allergic rhinitis Adults 18+ 2 sprays per nostril (200 mcg total) Once daily
Perennial allergic rhinitis Adults 18+ 2 sprays per nostril (200 mcg total) Once daily
Under 18 (OTC) Under 18 Not recommended without medical supervision

 

What Are the Possible Side Effects of Pirinase Nasal Spray?

 

Like all medicines, Pirinase can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nose and throat.

Common side effects (may affect up to 1 in 10 people):

  • Nasal irritation or dryness
  • Nosebleeds (epistaxis)
  • Unpleasant taste or smell
  • Headache

Less common side effects (may affect up to 1 in 100 people):

  • Nasal ulceration or crusting
  • Perforation of the nasal septum (rare, particularly with long-term use)
  • Raised intraocular pressure or glaucoma (with prolonged high-dose use)
  • Hypersensitivity reactions including rash, facial swelling, or difficulty breathing — seek immediate medical attention if these occur

If you experience persistent nosebleeds, visual disturbances, or any signs of an allergic reaction, stop using the spray and contact your GP or pharmacist promptly. For those also experiencing itchy, watery eyes alongside nasal symptoms, our ear, nose and throat range includes additional options that may help.

 

How Should You Store Pirinase Nasal Spray?

 

  • Store below 30°C — do not refrigerate or freeze
  • Keep the bottle upright at all times
  • Store away from direct sunlight and heat sources
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the label
  • Once opened, use within 2 months
  • Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Pirinase Hay Fever Nasal Spray online in the UK?

You can buy Pirinase Hay Fever Nasal Spray 60 Doses online from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £7.89. It is available without a prescription for adults aged 18 and over. Simply add it to your basket and it will be dispatched quickly to your door.

How does Pirinase Hay Fever Nasal Spray work in the body?

Pirinase contains fluticasone propionate, a corticosteroid that reduces inflammation in the lining of the nasal passages. When you are exposed to allergens like pollen, your immune system triggers the release of inflammatory chemicals — fluticasone suppresses this response locally. Because it acts directly in the nose rather than throughout the body, systemic side effects are minimal at the recommended dose.

How do I use Pirinase Hay Fever Nasal Spray step by step?

Blow your nose first, then shake the bottle gently. Tilt your head slightly forward, insert the nozzle into one nostril pointing slightly away from the septum, and press the pump once while breathing in slowly through your nose. Repeat in the other nostril, then breathe out through your mouth and replace the dust cap.

How long does Pirinase take to start working?

Pirinase typically takes three to four days of consistent daily use before you notice the full benefit. It is not a fast-acting rescue treatment — it works by gradually reducing nasal inflammation over time. For best results, start using it a few days before your hay fever season begins rather than waiting for symptoms to peak.

What is the correct dose of Pirinase for adults?

The standard adult dose is two sprays into each nostril once daily, giving a total daily dose of 200 micrograms of fluticasone propionate. Once your symptoms are well controlled, your pharmacist may advise reducing to one spray per nostril daily as a maintenance dose. Do not exceed two sprays per nostril per day.

What is the best time of day to use Pirinase Nasal Spray?

Most people find it easiest to use Pirinase in the morning, ideally before going outside during high pollen periods. Using it at the same time each day helps maintain consistent levels of the medicine in your nasal tissue. There is no strict requirement to use it in the morning, but a regular routine improves adherence and effectiveness.

What are the side effects of Pirinase Hay Fever Nasal Spray?

Common side effects include nasal irritation, dryness, and nosebleeds. Some people notice a mild headache or an unpleasant taste after use. Rare but more serious effects include nasal ulceration or, with prolonged high-dose use, raised eye pressure — if you notice visual changes, stop use and speak to your GP.

Is Pirinase Nasal Spray suitable for children?

Pirinase Hay Fever Nasal Spray is only licensed for over-the-counter use in adults aged 18 and over. Children under 18 should not use it without medical supervision, as a doctor may need to assess the appropriate dose and monitor for any effects on growth with long-term use. Speak to your GP if your child needs a corticosteroid nasal spray.

Can I use Pirinase if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should speak to your GP or pharmacist before using Pirinase. While systemic absorption is low at the recommended dose, there is limited data on its safety during pregnancy, and a healthcare professional should weigh up the benefits and risks for your individual situation.

What happens if I miss a dose of Pirinase?

If you forget to use Pirinase, simply use it as soon as you remember — unless it is nearly time for your next dose, in which case skip the missed one. Do not use a double dose to make up for a missed one. Missing the occasional dose is unlikely to cause a significant problem, but consistent daily use gives the best results.

How long can I use Pirinase Hay Fever Nasal Spray for?

Pirinase can be used throughout the hay fever season, but you should not use it continuously for more than three months without consulting a doctor or pharmacist. If your symptoms persist beyond this period or worsen, seek medical advice. Long-term unsupervised use of any corticosteroid nasal spray is not recommended.

What is the difference between Pirinase and Beconase nasal spray?

Pirinase contains fluticasone propionate, while Beconase contains beclometasone dipropionate — both are corticosteroid nasal sprays used for allergic rhinitis. Pirinase is dosed once daily (two sprays per nostril), whereas Beconase is typically used twice daily. Both are available OTC for adults aged 18 and over, and both require a few days of regular use to reach full effect.

Can I use Pirinase alongside antihistamine tablets?

Yes, Pirinase can generally be used alongside oral antihistamines for more complete hay fever symptom control. The nasal spray targets nasal inflammation directly, while antihistamines help with sneezing, itching, and eye symptoms. If you are considering combining treatments, it is worth speaking to your pharmacist — you can browse our full allergy and hay fever range for suitable options.

Does Pirinase interact with any other medicines?

The most clinically significant interaction is with strong CYP3A4 inhibitors such as ritonavir (used in HIV treatment) and ketoconazole, which can increase fluticasone levels in the blood and raise the risk of systemic corticosteroid effects. Using other corticosteroid medicines at the same time — whether inhaled, oral, or topical — may also increase this risk. Always tell your pharmacist about all medicines you are taking.

What are the latest findings on fluticasone nasal sprays for hay fever?

Intranasal corticosteroids like fluticasone propionate remain the most effective first-line treatment for moderate-to-severe allergic rhinitis according to current NHS and NICE guidance. Evidence consistently shows they outperform oral antihistamines for nasal congestion in particular. Research also supports their safety profile for seasonal use in adults when used at recommended doses.

How Should You Use Pirinase Hay Fever Nasal Spray?

Using Pirinase correctly is important — the technique affects how much medicine actually reaches the nasal lining. Before your very first use, you will need to prime the pump by pressing it down six times until a fine mist appears. After that, it is ready to use each day.

Follow these steps every time you use the spray:

What Is the Correct Dose of Pirinase Hay Fever Nasal Spray?

The standard adult dose is two sprays into each nostril once daily, delivering a total of 200 micrograms of fluticasone propionate per day. Once your symptoms are well controlled, your pharmacist may suggest reducing to one spray per nostril daily as a maintenance dose. Never exceed two sprays per nostril in a 24-hour period.

When Is the Best Time to Use Pirinase Hay Fever Nasal Spray?

Most people find it easiest to use Pirinase in the morning, before heading outside during high pollen periods. Using it at a consistent time each day helps maintain steady levels of the medicine in your nasal tissue, which is key to keeping inflammation under control. If you find mornings too rushed, any regular time of day will work — the important thing is consistency.

Ideally, start using Pirinase two to three days before you expect your hay fever symptoms to begin, rather than waiting until you are already symptomatic. This gives the medicine time to build up its anti-inflammatory effect in the nasal lining.

How Long Can You Use Pirinase Hay Fever Nasal Spray For?

Pirinase is suitable for use throughout the hay fever season, which in the UK typically runs from late March to September depending on which pollens affect you. However, you should not use it continuously for more than three months without speaking to a doctor or pharmacist, who can review whether ongoing treatment is appropriate.

If your symptoms persist year-round (perennial allergic rhinitis), longer-term use may be considered under medical supervision. Do not use this product to treat nasal symptoms caused by a cold or infection — it is specifically for allergic rhinitis.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Pirinase Nasal Spray?

Most people who use Pirinase Hay Fever Nasal Spray tolerate it well, particularly when used at the recommended dose. The most frequently reported side effects are localised to the nose and throat, and they tend to be mild.

  • Nasal irritation or dryness inside the nose
  • Nosebleeds (epistaxis) — usually minor and short-lived
  • Unpleasant taste or smell after use
  • Headache
  • Throat irritation

What Are the Less Common Side Effects of Pirinase Nasal Spray?

Less common side effects occur in fewer than 1 in 100 users. They are more likely with prolonged use or if the spray is used incorrectly — for example, if it is directed towards the nasal septum rather than the outer nasal wall.

  • Nasal ulceration or crusting inside the nose
  • Perforation of the nasal septum (rare, associated with long-term use)
  • Raised intraocular pressure or glaucoma (with prolonged high-dose use)
  • Cataracts (rare, with long-term use)
  • Slowed growth in children — this is why OTC use is restricted to adults aged 18 and over

What Are the Serious Side Effects of Pirinase Nasal Spray?

Serious side effects are uncommon but require prompt attention. Hypersensitivity reactions — including skin rash, facial swelling, difficulty breathing, or a sudden drop in blood pressure — can occur rarely. If you experience any of these, stop using the spray immediately and seek emergency medical help.

Prolonged use at higher than recommended doses may lead to systemic corticosteroid effects, including adrenal suppression. This is more likely if you are also using other corticosteroid medicines (inhaled, oral, or topical) at the same time. Visual disturbances such as blurred vision should also be reported to your GP without delay.

What Should You Do If You Experience Side Effects?

For mild side effects such as nasal dryness or minor nosebleeds, try rinsing your nose with saline solution and ensure you are using the correct technique — always aim the nozzle away from the septum. If nosebleeds are frequent or heavy, stop using the spray and speak to your pharmacist.

For any side effect that concerns you, or if symptoms worsen rather than improve after a week of use, contact your pharmacist or GP. You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Pirinase Nasal Spray Interact With Other Medicines?

The most clinically important interaction is with strong CYP3A4 inhibitors — medicines such as ritonavir (used in HIV treatment) and ketoconazole (an antifungal). These can significantly increase the amount of fluticasone absorbed into the bloodstream, raising the risk of systemic corticosteroid effects. Concurrent use of other corticosteroids — whether inhaled for asthma, applied to the skin, or taken orally — may also increase this risk.

Always tell your pharmacist about every medicine you are taking, including over-the-counter products and herbal remedies, before starting Pirinase. This is especially important if you have asthma and are already using an inhaled corticosteroid.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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