Pernaton Gel 125ml

What Is Pernaton Gel and How Can It Help Your Joints?

Pernaton Gel is a topical gel formulated with green lipped mussel extract (derived from Perna canaliculus), a natural marine ingredient that has been used for decades to support joint comfort and mobility. If you live with aching knees, stiff hips, or the day-to-day discomfort of arthritis, you'll know how much it can affect even the simplest tasks. This gel offers a non-oral option for people who prefer to target relief directly at the source. At just £9.99 for a 125ml tube, it's an accessible addition to your joint care routine. You can also explore our wider range of pain relief products if you're looking for complementary options.

Joint pain is incredibly common in the UK. According to the NHS, around 10 million people in England alone are affected by arthritis, and many more experience musculoskeletal discomfort that doesn't always have a clear diagnosis. Topical preparations like this gel are often recommended as a first-line approach because they carry a lower risk of systemic side effects compared to oral anti-inflammatory medicines.

How Does Pernaton Gel Work on Joints?

The active ingredient in Pernaton Gel is green lipped mussel extract, which is rich in glycosaminoglycans — naturally occurring compounds that form part of the cartilage matrix in your joints. When applied topically, the gel is thought to penetrate the skin and deliver these compounds to the underlying joint tissue, where they may help support cartilage structure and reduce localised inflammation.

• Green lipped mussel extract contains glycosaminoglycans, including chondroitin sulphate, which are structural components of joint cartilage
• The extract also provides omega-3 fatty acids, which have recognised anti-inflammatory properties
• The gel base helps carry the active compounds through the skin to the target area
• Regular application may help maintain joint lubrication and reduce stiffness over time

Who Should Consider Using Pernaton Gel?

This gel is designed for adults who experience joint discomfort, stiffness, or reduced mobility. It's particularly well-suited to people who prefer a topical approach rather than taking oral tablets or capsules. That said, it's not a replacement for medical treatment — if your symptoms are severe or worsening, always speak to your GP.

• Adults with mild to moderate osteoarthritis of the knees, hips, or hands
• People experiencing general joint stiffness, particularly in the morning
• Those who want to complement their existing joint supplement routine
• Individuals who prefer not to take oral anti-inflammatory medicines

It is not suitable for children, and should not be used by anyone with a known allergy to shellfish or molluscs, as the mussel extract is derived from seafood.

How Does Pernaton Gel Compare to Other Topical Joint Gels?

Is Pernaton Gel Safe to Use Alongside Supplements?

Many people who use Pernaton Gel also take oral joint supplements such as glucosamine or fish oil capsules. There are no known interactions between this topical gel and common oral supplements, but it's always sensible to mention everything you're taking to your pharmacist. If you're already browsing vitamins and supplements for joint support, combining an oral supplement with a topical gel like this one may offer a more rounded approach to joint care — though the evidence for combined use varies between individuals.

Store the gel below 25°C, away from direct sunlight, and keep it out of reach of children. For external use only — avoid contact with eyes, mucous membranes, or broken skin.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

What Is Pernaton Gel and What Is It Used For?

Pernaton Gel is a topical preparation containing green lipped mussel extract, intended for external application to joints and surrounding soft tissue. It is used to help relieve the symptoms of joint pain, stiffness, and reduced mobility — particularly in people with osteoarthritis or general musculoskeletal discomfort. The NHS notes that osteoarthritis is the most common type of arthritis in the UK, affecting millions of people, and that self-care measures including topical treatments can play a meaningful role in day-to-day symptom management.

This product is available over the counter without a prescription. It is not a cure for arthritis or any underlying joint condition, but it may help reduce discomfort and support joint function when used regularly as part of a broader self-care plan.

What Do You Need to Know Before Using Pernaton Gel?

Before applying this gel, read the following carefully. There are certain situations where you should not use this product, and others where extra caution is needed.

Do not use Pernaton Gel if you:

• Have a known allergy to shellfish, molluscs, or any ingredient in the gel
• Have broken, infected, or inflamed skin at the application site
• Are a child under 18 years of age
• Are pregnant or breastfeeding, unless advised by a healthcare professional

Use with caution if you:

• Have sensitive skin or a history of contact dermatitis
• Are using other topical preparations on the same area
• Have an underlying medical condition affecting the skin or joints

Known drug interactions:

• No significant drug interactions have been identified for topical green lipped mussel extract
• Avoid applying alongside other topical NSAIDs or medicated creams on the same skin area without pharmacist advice

How Should You Use Pernaton Gel?

Always follow the instructions provided with the product. The steps below reflect standard guidance for topical joint gels. If you are unsure, ask your pharmacist before use.

1. Clean and dry the skin over the affected joint before application
2. Squeeze a small amount of gel (approximately 2–3cm) onto your fingertips
3. Apply gently to the skin over the painful or stiff joint
4. Massage in using circular motions until the gel is fully absorbed
5. Wash your hands thoroughly after application, unless treating the hands themselves
6. Allow the area to dry before covering with clothing or bandaging

If you are also using creams and ointments for other skin conditions, avoid applying them to the same area at the same time as Pernaton Gel unless your pharmacist has confirmed this is safe.

What Are the Possible Side Effects of Pernaton Gel?

Like all medicines, Pernaton Gel can cause side effects, although not everyone experiences them. Because it is applied topically, side effects are generally localised to the skin at the application site.

Common side effects:

• Mild skin irritation at the application site
• Temporary redness or warmth of the skin
• Slight tingling sensation after application

Less common side effects:

• Itching or a rash at the application site
• Dry or flaking skin with prolonged use
• Allergic contact dermatitis (rare — seek medical advice if this occurs)

If you notice any signs of a more serious allergic reaction — such as swelling of the face, lips, or throat, or difficulty breathing — stop using the gel immediately and seek emergency medical attention. The NHS advises that allergic reactions to shellfish-derived products can occasionally be severe in sensitised individuals.

How Should You Store Pernaton Gel?

Correct storage helps maintain the quality and effectiveness of the gel throughout its shelf life. Follow these guidelines:

• Store below 25°C in a cool, dry place
• Keep away from direct sunlight and sources of heat
• Do not freeze
• Keep the cap tightly closed when not in use
• Keep out of the reach and sight of children
• Do not use after the expiry date printed on the tube
• Do not dispose of medicines via wastewater or household waste — return unused product to your pharmacist

If you're managing multiple health conditions and looking for a convenient way to order your products, you can browse our first aid range alongside your joint care essentials at Cured Pharmacy.