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Otrivine Congestion Relief Nasal Spray 10ml

Otrivine Congestion Relief Nasal Spray 10ml

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  • ✔️ Relieves blocked nose caused by colds, sinusitis, and hay fever
  • ✔️ Contains xylometazoline 0.1% for targeted nasal decongestion
  • ✔️ Works within minutes and lasts up to 10 hours per dose
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Compact 10ml bottle — easy to carry and use on the go

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What Is Otrivine Nasal Spray and How Does It Relieve Congestion?

 

A blocked nose can make even the simplest things — sleeping, concentrating, breathing comfortably — feel like a real effort. Otrivine nasal spray is a well-established, over-the-counter decongestant that works quickly to clear nasal congestion caused by colds, sinusitis, and allergic rhinitis, including hay fever. Each 10ml bottle contains xylometazoline hydrochloride 0.1%, a sympathomimetic agent that has been used in nasal decongestants for decades. If you're looking for fast, targeted relief, this is one of the most widely recognised options available in UK pharmacies. You can also explore our full range of ear, nose, and throat products if you need additional support for related symptoms.

Otrivine is classified as a pharmacy (P) medicine in the UK, meaning it can be purchased without a prescription but should be used according to the label instructions. It is suitable for adults and children aged 12 and over. At just £4.99 for a 10ml bottle, it offers accessible relief without the need for a GP appointment.

 

How Does Otrivine Congestion Relief Nasal Spray Work?

 

The active ingredient, xylometazoline hydrochloride, belongs to a class of medicines called alpha-adrenergic agonists. When sprayed into the nostril, it acts directly on the blood vessels lining the nasal mucosa. Here's what happens:

  • Xylometazoline binds to alpha-adrenergic receptors in the nasal blood vessel walls.
  • This causes vasoconstriction — the blood vessels narrow.
  • Narrowed vessels reduce swelling of the nasal lining (mucosa).
  • The nasal passages open up, making it easier to breathe through your nose.
  • Relief typically begins within a few minutes and can last up to 10 hours.

It's worth noting that Otrivine treats the symptom of congestion — it doesn't address the underlying cause, whether that's a viral infection or an allergic reaction. So if hay fever is the culprit, you may want to combine it with an antihistamine for broader symptom control.

 

Who Should Use Otrivine Congestion Relief Nasal Spray?

 

This nasal spray is designed for adults and young people aged 12 and over who are experiencing nasal congestion. It's particularly useful when congestion is making it difficult to sleep, work, or go about daily life. That said, it's not suitable for everyone — always read the label before use.

Otrivine may be appropriate for you if you:

  • Have a blocked nose due to a common cold or upper respiratory tract infection.
  • Are experiencing nasal congestion as part of sinusitis.
  • Suffer from allergic rhinitis or hay fever-related nasal blockage.
  • Need short-term relief (up to 7 days) without a prescription.

 

How Does Otrivine Nasal Spray Compare to Other Decongestant Sprays?

 

Feature Otrivine Congestion Relief Nasal Spray Sudafed Blocked Nose Spray
Active ingredient Xylometazoline hydrochloride 0.1% Xylometazoline hydrochloride 0.1%
Volume 10ml 10ml
Suitable age 12 years and over 12 years and over
Max duration of use 7 consecutive days 7 consecutive days

 

Is Otrivine Nasal Spray Safe to Store at Home?

 

Yes — Otrivine nasal spray is straightforward to store. Keep it below 25°C, away from direct sunlight, and out of reach of children. Once opened, it should be used within the recommended period stated on the packaging. Do not share the bottle with others, as this can spread infection. If you're managing multiple symptoms alongside congestion — such as itchy eyes from hay fever — you might also find our allergy and hay fever collection helpful for a more complete approach to symptom relief.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Otrivine Congestion Relief Nasal Spray 10ml specifications
Treatment category Nasal decongestant
Mechanism of action Alpha-adrenergic agonist — causes vasoconstriction of nasal blood vessels
Effective for Nasal congestion due to colds, sinusitis, and allergic rhinitis
Suitable for Adults and children aged 12 years and over
Active ingredient Xylometazoline hydrochloride 0.1%
Pack size 10ml
Strength 0.1% w/v
UK classification Pharmacy (P) medicine
Drug class Sympathomimetic / alpha-adrenergic agonist
Preparation Nasal spray solution
Route of administration Intranasal

Specifications of Otrivine Congestion Relief Nasal Spray 10ml

 

What Is Otrivine Congestion Relief Nasal Spray and What Is It Used For?

 

Otrivine Congestion Relief Nasal Spray 10ml is an over-the-counter nasal decongestant containing xylometazoline hydrochloride 0.1%. It is used to relieve the symptoms of nasal congestion — that stuffy, blocked feeling in your nose — caused by a range of conditions. The NHS recognises nasal congestion as a common symptom of colds, flu, sinusitis, and allergic rhinitis (including hay fever). Otrivine nasal spray works locally in the nose to reduce swelling and open up the nasal passages, helping you breathe more freely.

It is intended for short-term use only — no more than 7 consecutive days. It does not treat the underlying cause of your congestion, whether that's a viral infection or an allergy. Think of it as targeted, temporary relief while your body recovers or while you manage the root cause with other treatments.

 

What Do You Need to Know Before Using Otrivine Congestion Relief Nasal Spray?

 

Before using this spray, it's important to check whether it's right for you. Do not use Otrivine if any of the following apply:

  • You are under 12 years of age.
  • You have had surgery on your pituitary gland (transsphenoidal hypophysectomy).
  • You have dry nasal inflammation (atrophic rhinitis).
  • You are allergic to xylometazoline hydrochloride or any other ingredient in the spray.
  • You are taking or have recently taken monoamine oxidase inhibitors (MAOIs) — leave at least 14 days between stopping MAOIs and using this product.

Speak to your pharmacist or GP before using Otrivine if you have any of the following conditions:

  • High blood pressure (hypertension).
  • Heart disease or irregular heartbeat.
  • An overactive thyroid (hyperthyroidism).
  • Diabetes mellitus.
  • Enlarged prostate (benign prostatic hyperplasia).
  • Glaucoma (raised pressure in the eye).
  • Phaeochromocytoma (a rare adrenal gland tumour).

Drug interactions to be aware of:

  • MAOIs — risk of hypertensive crisis; do not use together.
  • Tricyclic antidepressants (e.g. amitriptyline) — may increase cardiovascular effects.
  • Other sympathomimetic medicines — additive effects possible.

If you are pregnant or breastfeeding, seek medical advice before use. Xylometazoline is not recommended during pregnancy without guidance from a healthcare professional.

 

How Should You Use Otrivine Congestion Relief Nasal Spray?

 

Always use this medicine exactly as described on the label or as directed by your pharmacist. The spray is for nasal use only — never swallow it or use it in the eyes.

  1. Blow your nose gently to clear the nasal passages before use.
  2. Remove the protective cap from the nozzle.
  3. Tilt your head slightly forward.
  4. Insert the nozzle carefully into one nostril.
  5. Press the pump firmly once while breathing in gently through your nose.
  6. Repeat in the other nostril if needed.
  7. Replace the cap after use and wipe the nozzle clean.
  8. Do not share the bottle with anyone else.
Indication Age Group Dose Frequency
Nasal congestion (cold, sinusitis, hay fever) Adults and children 12+ 1 spray per nostril Up to 3 times daily
Nasal congestion Under 12 years Not suitable Do not use

If you are also managing cold and flu symptoms more broadly, our cold and flu collection includes a range of complementary products that may help.

 

What Are the Possible Side Effects of Otrivine Congestion Relief Nasal Spray?

 

Like all medicines, Otrivine can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the nose.

Common side effects:

  • Temporary nasal dryness or irritation.
  • Burning or stinging sensation in the nose after application.
  • Sneezing shortly after use.
  • Increased nasal discharge (runny nose).

Less common side effects:

  • Rebound congestion (rhinitis medicamentosa) — particularly with use beyond 7 days.
  • Headache.
  • Nausea.
  • Palpitations or increased heart rate (rare).
  • Raised blood pressure (rare, more likely in those with pre-existing hypertension).
  • Insomnia or restlessness (rare).

Stop using the spray and seek medical advice if you experience chest pain, a very fast or irregular heartbeat, or severe headache. These could indicate a more serious reaction.

 

How Should You Store Otrivine Congestion Relief Nasal Spray?

 

Proper storage helps maintain the effectiveness of the spray and keeps it safe for use. You might also want to browse our allergy and hay fever range for additional products to store alongside it during hay fever season.

  • Store below 25°C.
  • Keep away from direct sunlight and heat sources.
  • Do not freeze.
  • Keep the bottle tightly capped when not in use.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the label.
  • Do not share the bottle with other people.
  • Dispose of any unused medicine safely — ask your pharmacist how to do this.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Otrivine nasal spray online in the UK?

You can buy Otrivine Congestion Relief Nasal Spray 10ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £4.99. No prescription is needed, as it is an over-the-counter pharmacy medicine. Simply add it to your basket and it will be dispatched to your door.

How does Otrivine nasal spray work in the body?

Otrivine contains xylometazoline hydrochloride, which acts as an alpha-adrenergic agonist. It narrows the blood vessels inside the nasal passages, reducing swelling of the nasal lining and opening up the airways so you can breathe more easily. The effect typically begins within a few minutes of application.

How do I use Otrivine nasal spray step by step?

Blow your nose gently first, then tilt your head slightly forward. Insert the nozzle into one nostril and press the pump once while breathing in gently through your nose. Repeat in the other nostril if needed, replace the cap, and wipe the nozzle clean after each use. Never share the bottle with anyone else.

How quickly does Otrivine nasal spray start to work?

Otrivine typically begins to relieve nasal congestion within a few minutes of use. The decongestant effect can last for up to 10 hours, which means many people only need to use it two to three times a day. Individual response times may vary slightly.

What is the correct dose of Otrivine nasal spray for adults?

The recommended dose for adults and children aged 12 and over is one spray into each nostril, up to three times daily. Do not exceed three applications in 24 hours. Always follow the instructions on the label or as directed by your pharmacist.

Can I use Otrivine nasal spray for hay fever?

Yes — Otrivine can relieve nasal congestion associated with hay fever and allergic rhinitis. However, it does not address the underlying allergic response, so you may benefit from combining it with an antihistamine. Browse our allergy and hay fever collection for additional options.

How long can you use Otrivine nasal spray for?

Otrivine should not be used for more than 7 consecutive days. Using it for longer than this can cause rebound congestion — a condition called rhinitis medicamentosa — where the nose becomes more blocked when you stop the spray. If your symptoms persist beyond a week, speak to your pharmacist or GP.

What are the side effects of Otrivine nasal spray?

Common side effects include temporary nasal dryness, stinging, burning, or sneezing after use. Less commonly, some people experience headache, nausea, or rebound congestion with prolonged use. Rare side effects include palpitations or raised blood pressure — stop use and seek advice if these occur.

How do I manage rebound congestion from Otrivine nasal spray?

Rebound congestion (rhinitis medicamentosa) occurs when the nasal spray is used for too long and the nose becomes dependent on it. The best approach is to gradually reduce use and speak to your GP or pharmacist, who may recommend a steroid nasal spray to help during the withdrawal period. Avoiding use beyond 7 days is the most effective prevention.

Who should not use Otrivine nasal spray?

Otrivine is not suitable for children under 12 years of age, people with atrophic rhinitis, or those who have recently had transsphenoidal pituitary surgery. It should also be avoided by people taking MAOIs or those with uncontrolled high blood pressure, glaucoma, or hyperthyroidism without medical advice first.

Is Otrivine nasal spray safe during pregnancy?

Otrivine is not recommended during pregnancy without first speaking to your GP or midwife, as xylometazoline may affect blood flow. The safety of this medicine during breastfeeding is also uncertain, so always seek professional advice before using any nasal decongestant if you are pregnant or nursing.

Can Otrivine nasal spray interact with other medicines?

Yes — Otrivine can interact with monoamine oxidase inhibitors (MAOIs), which can cause a dangerous rise in blood pressure. It may also interact with tricyclic antidepressants and other sympathomimetic medicines. Always tell your pharmacist about all medicines you are taking before using Otrivine.

What happens if I use too much Otrivine nasal spray?

Using more than the recommended dose can increase the risk of side effects such as raised blood pressure, rapid heartbeat, headache, and nausea. In children, accidental ingestion can be particularly dangerous. If you think you or someone else has used too much, contact NHS 111 or go to your nearest A&E immediately.

What are the alternatives to Otrivine nasal spray?

Alternatives include other xylometazoline-based sprays such as Sudafed Blocked Nose Spray, or oxymetazoline-based products like Vicks Sinex. For longer-term management of allergic rhinitis, corticosteroid nasal sprays such as Beconase or Flixonase may be more appropriate — speak to your pharmacist for guidance. You can also explore our ear, nose, and throat range for more options.

What is the latest guidance on using nasal decongestant sprays?

Current NHS and clinical guidance consistently advises limiting nasal decongestant sprays containing xylometazoline to a maximum of 7 consecutive days to avoid rebound congestion. For persistent or recurrent nasal congestion, healthcare professionals typically recommend intranasal corticosteroids as a safer long-term option. Always follow up with your GP if symptoms do not improve within a week.

How Should You Use Otrivine Congestion Relief Nasal Spray?

Using Otrivine correctly ensures you get the most effective relief with the least risk of side effects. Always read the label before use and follow these steps carefully.

Here's how to use the spray properly:

What Is the Correct Dose of Otrivine Congestion Relief Nasal Spray?

The dose depends on your age. This spray is not suitable for children under 12 years old. Always stick to the recommended dose — using more will not improve results and increases the risk of side effects.

When Is the Best Time to Use Otrivine Congestion Relief Nasal Spray?

There is no single fixed time of day you must use Otrivine, but many people find it most helpful in the morning to clear congestion at the start of the day, and again in the evening before bed to help with sleep. Because the effect can last up to 10 hours, spacing doses evenly throughout the day — for example morning, afternoon, and evening — works well for most people. Avoid using it immediately before lying down flat, as this can affect how the spray distributes inside the nasal passages.

How Long Can You Use Otrivine Congestion Relief Nasal Spray For?

Otrivine should only be used for a maximum of 7 consecutive days. Using it for longer than this can lead to a condition called rhinitis medicamentosa, or rebound congestion, where the nasal passages become more blocked when you stop the spray than they were before you started. If your congestion has not improved after 7 days, or if it keeps coming back, speak to your pharmacist or GP. They can help identify the underlying cause and recommend a more suitable long-term treatment, such as a corticosteroid nasal spray.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Otrivine Congestion Relief Nasal Spray?

Most people use Otrivine without experiencing significant problems, but like all medicines, it can cause side effects in some individuals. The most common ones are mild and affect the nose directly.

  • Temporary nasal dryness or irritation after application.
  • A burning or stinging sensation inside the nose.
  • Sneezing shortly after using the spray.
  • Increased nasal discharge (runny nose) immediately after use.

These effects are usually short-lived and settle on their own. If they persist or become bothersome, stop using the spray and speak to your pharmacist.

What Are the Less Common Side Effects of Otrivine Congestion Relief Nasal Spray?

Some people may experience side effects that are less frequent but worth being aware of, particularly if you use the spray regularly or for longer than recommended.

  • Rebound congestion (rhinitis medicamentosa) — the nose becomes more blocked after stopping the spray, especially with use beyond 7 days.
  • Headache.
  • Nausea.
  • Insomnia or restlessness.
  • Dry mouth or throat.

Rebound congestion is the most clinically significant concern with prolonged use. If you notice your congestion worsening each time the spray wears off, this may be a sign of dependence — speak to your GP or pharmacist promptly.

What Are the Serious Side Effects of Otrivine Congestion Relief Nasal Spray?

Serious side effects are rare when Otrivine is used as directed, but they can occur — particularly in people with pre-existing cardiovascular conditions or those who use more than the recommended dose.

  • Palpitations or a noticeably fast or irregular heartbeat.
  • Raised blood pressure (hypertension).
  • Chest pain or tightness.
  • Severe headache.
  • Tremor or agitation.

If you experience any of these symptoms, stop using the spray immediately and seek urgent medical advice. Do not use Otrivine if you have uncontrolled high blood pressure or a serious heart condition without first speaking to your doctor.

What Should You Do If You Experience Side Effects of Otrivine Congestion Relief Nasal Spray?

For mild side effects such as nasal dryness or stinging, simply reducing the frequency of use or stopping the spray is usually sufficient. For more concerning effects — such as palpitations, chest pain, or a severe headache — stop use immediately and contact NHS 111 or your GP. If you believe you or someone else has used too much of the spray, particularly a child who may have swallowed it, go to your nearest A&E or call 999 without delay. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Otrivine Congestion Relief Nasal Spray Interact With Other Medicines?

Yes — Otrivine can interact with certain medicines, and it's important to tell your pharmacist about everything you are taking before use. The most significant interactions include monoamine oxidase inhibitors (MAOIs), which can cause a dangerous rise in blood pressure when combined with xylometazoline. You should wait at least 14 days after stopping an MAOI before using this spray. Tricyclic antidepressants (such as amitriptyline) and other sympathomimetic medicines may also increase the cardiovascular effects of xylometazoline. Always check with your pharmacist if you are unsure.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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