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Otrivine Adult Metered Dose Nasal Spray - 10ml

Otrivine Adult Metered Dose Nasal Spray - 10ml

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  • ✔️ Relieves nasal congestion fast — works within minutes
  • ✔️ Metered dose pump delivers precise, consistent spray each time
  • ✔️ Long-lasting relief — decongestant effect lasts up to 10 hours
  • ✔️ Suitable for colds, sinusitis, and hay fever-related congestion
  • ✔️ Compact 10ml bottle — easy to carry and use on the go

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Is Otrivine Nasal Spray Right for Your Blocked Nose?

 

A blocked nose can make even the simplest things — sleeping, concentrating, breathing through your nose — feel like a real effort. Otrivine nasal spray is one of the most widely recognised over-the-counter decongestants available in the UK, and for good reason. The Otrivine Adult Metered Dose Nasal Spray 10ml delivers a precise, measured dose of xylometazoline hydrochloride 0.1% directly into the nasal passages, helping to shrink swollen blood vessels and restore airflow quickly. Whether your congestion is down to a cold, sinusitis, or hay fever, this spray is designed to give you fast, targeted relief. If you're also dealing with other cold and flu symptoms alongside your blocked nose, you might find our cold and flu range useful too.

Each spray delivers a consistent, metered dose — so there's no guesswork involved. The 10ml bottle is compact enough to carry in a bag or keep on a bedside table, making it practical for everyday use.

 

How Does Otrivine Adult Metered Dose Nasal Spray Work?

 

The active ingredient, xylometazoline hydrochloride, belongs to a class of medicines called alpha-adrenergic agonists. When sprayed into the nose, it acts directly on the blood vessels in the nasal mucosa. Here's what happens:

  • Xylometazoline binds to alpha-adrenergic receptors in the nasal blood vessel walls.
  • This causes vasoconstriction — the blood vessels narrow.
  • Swelling of the nasal lining reduces, opening up the nasal passages.
  • Mucus secretion decreases, making it easier to breathe through your nose.
  • Relief typically begins within a few minutes and can last up to 10 hours.

Because the spray acts locally rather than being absorbed into the bloodstream in significant amounts, it tends to have fewer systemic side effects than oral decongestants — though it's still important to use it correctly and not exceed the recommended duration of use.

 

Who Should Use Otrivine Adult Metered Dose Nasal Spray?

 

This spray is intended for adults and young people aged 12 and over. It's suitable for short-term relief of nasal congestion caused by a range of common conditions. You might find it helpful if you experience:

  • Nasal congestion due to the common cold or flu
  • Blocked nose associated with sinusitis
  • Congestion triggered by allergic rhinitis or hay fever
  • Nasal stuffiness that disrupts sleep or daily activities

It is not suitable for children under 12 years of age. If you're pregnant, breastfeeding, or managing a long-term health condition such as high blood pressure, diabetes, or thyroid disease, speak to your pharmacist or GP before using this product.

 

How Does Otrivine Compare to Other Nasal Decongestant Sprays?

 

Feature Otrivine Adult Metered Dose Nasal Spray Sudafed Blocked Nose Spray (Oxymetazoline)
Active ingredient Xylometazoline hydrochloride 0.1% Oxymetazoline hydrochloride 0.05%
Onset of action Within minutes Within minutes
Duration of effect Up to 10 hours Up to 12 hours
Maximum duration of use 7 consecutive days 7 consecutive days
Suitable age 12 years and over 12 years and over
Dose delivery Metered dose pump Metered dose pump

 

Is Otrivine Nasal Spray Safe to Store and Use Long-Term?

 

Storage is straightforward. Keep the bottle below 25°C, away from direct sunlight, and out of reach of children. Do not use the spray after the expiry date printed on the packaging. Once opened, the bottle should be used within the timeframe stated in the patient information leaflet — typically within 28 days.

It's worth being clear about long-term use: this product is not intended for ongoing, daily use. Using any xylometazoline-based nasal spray for more than 7 consecutive days can lead to a condition called rhinitis medicamentosa — sometimes called rebound congestion — where the nose becomes more blocked when you stop using the spray. If your congestion persists beyond a week, speak to your GP. For those whose blocked nose is linked to seasonal allergies, our allergy and hay fever range may offer longer-term options worth exploring.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Otrivine Adult Metered Dose Nasal Spray - 10ml specifications
Treatment category Nasal decongestant
Mechanism of action Alpha-adrenergic agonist — causes vasoconstriction of nasal blood vessels
Effective for Nasal congestion due to colds, sinusitis, and allergic rhinitis
Suitable for Adults and young people aged 12 years and over
Active ingredient Xylometazoline hydrochloride 0.1%
Pack size 10ml
Strength 0.1% w/v
UK classification General Sale List (GSL)
Drug class Sympathomimetic / nasal decongestant
Preparation Nasal spray solution
Route of administration Intranasal

Specifications of Otrivine Adult Metered Dose Nasal Spray - 10ml

 

What Is Otrivine Adult Metered Dose Nasal Spray and What Is It Used For?

 

Otrivine Adult Metered Dose Nasal Spray is an over-the-counter nasal decongestant containing xylometazoline hydrochloride 0.1%. It is used to relieve nasal congestion — that uncomfortable blocked, stuffy feeling in your nose — caused by conditions including the common cold, sinusitis, and allergic rhinitis (including hay fever). The spray works locally in the nasal passages to reduce swelling and open up the airways, helping you breathe more freely. It is suitable for adults and young people aged 12 years and over and is available without a prescription.

 

What Do You Need to Know Before Using Otrivine Adult Metered Dose Nasal Spray?

 

Before using this spray, it's important to check whether it is appropriate for you. Do not use Otrivine Adult Metered Dose Nasal Spray if any of the following apply:

  • You are under 12 years of age
  • You are allergic to xylometazoline hydrochloride or any other ingredient in the spray
  • You have had surgery involving the dura mater (the membrane surrounding the brain and spinal cord)
  • You have dry nasal inflammation (rhinitis sicca atrophicans)
  • You are currently taking or have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days

Speak to your pharmacist or GP before using this product if you have:

  • High blood pressure (hypertension)
  • Heart disease or an irregular heartbeat
  • An overactive thyroid (hyperthyroidism)
  • Diabetes mellitus
  • Phaeochromocytoma (a rare adrenal gland tumour)
  • Glaucoma (raised pressure in the eye)
  • An enlarged prostate gland

Known drug interactions to be aware of include:

  • MAOIs — risk of hypertensive crisis; do not use together
  • Tricyclic antidepressants (e.g. amitriptyline) — may enhance the cardiovascular effects of xylometazoline
  • Other sympathomimetic medicines — additive effects possible

If you are pregnant or breastfeeding, seek medical advice before use. Xylometazoline should be used with caution during pregnancy, particularly in the first trimester.

 

How Should You Use Otrivine Adult Metered Dose Nasal Spray?

 

Always use this spray exactly as described in the patient information leaflet. The metered dose pump ensures you receive a consistent amount of medicine with each press. Follow these steps:

  1. Blow your nose gently to clear the nasal passages before use.
  2. Remove the protective cap from the nozzle.
  3. If using for the first time, prime the pump by pressing it several times until a fine mist appears.
  4. Tilt your head slightly forward and insert the nozzle into one nostril, keeping the other nostril closed with a finger.
  5. Press the pump once firmly while breathing in gently through your nose.
  6. Breathe out through your mouth.
  7. Repeat for the other nostril if needed.
  8. Replace the protective cap after use.
Indication Age Group Dose Frequency
Nasal congestion (cold, sinusitis, hay fever) Adults and young people aged 12+ 1 spray per nostril Up to 2–3 times daily
Nasal congestion Under 12 years Not suitable — do not use

Do not use more than the recommended dose. Do not use for more than 7 consecutive days without medical advice. If you're also managing ear, nose, or throat symptoms more broadly, our ear, nose and throat range includes a variety of products that may help.

 

What Are the Possible Side Effects of Otrivine Adult Metered Dose Nasal Spray?

 

Like all medicines, Otrivine can cause side effects, although not everyone experiences them. Knowing what to look out for helps you use the product safely.

Common side effects (may affect up to 1 in 10 people):

  • Temporary burning or stinging sensation in the nose
  • Nasal dryness or irritation
  • Increased nasal secretions shortly after use
  • Sneezing

Less common side effects (may affect up to 1 in 100 people):

  • Headache
  • Nausea
  • Palpitations or increased heart rate
  • Rebound congestion (rhinitis medicamentosa) with prolonged use beyond 7 days
  • Insomnia or restlessness, particularly if used late in the evening

If you experience any severe or unexpected reactions, stop using the spray and seek medical advice promptly. If you need additional support managing pain or discomfort alongside your cold symptoms, our pain relief range may be worth browsing.

 

How Should You Store Otrivine Adult Metered Dose Nasal Spray?

 

  • Store below 25°C in a cool, dry place.
  • Keep away from direct sunlight and heat sources.
  • Keep out of the sight and reach of children.
  • Do not use after the expiry date printed on the bottle and carton.
  • Do not share the spray with other people — this is for hygiene reasons and to prevent cross-infection.
  • Once opened, use within 28 days (check the patient information leaflet for confirmation).
  • Do not dispose of medicines via wastewater or household waste — return unused medicines to your pharmacy.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Otrivine nasal spray online in the UK?

You can buy Otrivine Adult Metered Dose Nasal Spray 10ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £4.85. It's available without a prescription and can be ordered quickly and discreetly. No GP visit needed — simply add it to your basket and check out.

How does Otrivine nasal spray work in the body?

Otrivine contains xylometazoline hydrochloride, which acts as an alpha-adrenergic agonist. It binds to receptors in the blood vessel walls of the nasal lining, causing them to constrict and reducing the swelling that causes congestion. The effect is localised to the nose, so it works quickly without significantly affecting the rest of your body.

How do I use Otrivine Adult Metered Dose Nasal Spray step by step?

Start by blowing your nose gently, then prime the pump if it's a new bottle. Insert the nozzle into one nostril, close the other with a finger, and press the pump once while breathing in gently through your nose. Repeat for the other nostril, then replace the cap. Use up to two to three times daily, but never more than the recommended dose.

How long does Otrivine nasal spray take to work?

Most people notice relief from nasal congestion within a few minutes of using Otrivine. The decongestant effect can last for up to 10 hours, which makes it suitable for use during the day or before bed. Individual responses can vary depending on the severity of congestion.

What is the correct dose of Otrivine Adult Metered Dose Nasal Spray?

For adults and young people aged 12 and over, the recommended dose is one spray into each nostril, up to two to three times daily. Do not use more than the stated dose, and do not use for more than 7 consecutive days without speaking to a healthcare professional. There is no approved dose for children under 12 — this product is not suitable for them.

What are the side effects of Otrivine nasal spray?

Common side effects include temporary nasal burning, stinging, dryness, or sneezing after use. Less commonly, some people experience headache, nausea, or palpitations. Using the spray for longer than 7 days can cause rebound congestion, where the nose becomes more blocked when you stop — this is why short-term use is important.

Who should not use Otrivine Adult Metered Dose Nasal Spray?

This spray is not suitable for children under 12 years, people taking MAOIs or tricyclic antidepressants, or those with certain conditions such as uncontrolled high blood pressure, phaeochromocytoma, or a history of surgery involving the dura mater. If you have diabetes, glaucoma, thyroid disease, or heart problems, speak to your pharmacist before use. Pregnant or breastfeeding women should also seek medical advice first.

How long can you use Otrivine nasal spray for?

You should not use Otrivine for more than 7 consecutive days. Prolonged use beyond this can lead to rhinitis medicamentosa — a form of rebound congestion where the nasal passages become reliant on the decongestant to stay open. If your symptoms persist after a week, see your GP to identify the underlying cause.

Can I use Otrivine nasal spray if I have high blood pressure?

If you have high blood pressure, you should speak to your pharmacist or GP before using Otrivine. Xylometazoline can potentially affect blood pressure, particularly if it is not well controlled. Your healthcare professional can advise whether this product is appropriate for you or suggest a safer alternative.

Can I use Otrivine nasal spray during pregnancy?

Otrivine should be used with caution during pregnancy, especially during the first trimester, as xylometazoline may affect blood flow. You should always consult your GP or midwife before using any nasal decongestant while pregnant. Saline nasal rinses are often recommended as a safer first-line option during pregnancy.

What happens if I use Otrivine nasal spray for too long?

Using Otrivine for more than 7 consecutive days can cause a condition called rhinitis medicamentosa, or rebound congestion. This means your nose may feel more blocked than before once you stop using the spray, creating a cycle of dependency. If this happens, speak to your GP — gradual withdrawal or switching to a steroid nasal spray may be recommended.

What are alternatives to Otrivine nasal spray for a blocked nose?

Alternatives include other xylometazoline-based sprays, oxymetazoline sprays (such as Sudafed Blocked Nose Spray), or saline nasal rinses for milder congestion. For congestion linked to allergies, antihistamines or corticosteroid nasal sprays may be more appropriate for longer-term management — you can explore options in our allergy and hay fever range. Always speak to a pharmacist if you're unsure which product suits your symptoms best.

Can I use Otrivine nasal spray with other cold and flu medicines?

Some combination cold and flu remedies already contain a decongestant, so using Otrivine at the same time could mean you're doubling up on the same type of medicine. Always check the ingredients of any other cold remedy you're taking before using Otrivine alongside it. If in doubt, ask your pharmacist — they can check for interactions quickly and safely.

Is Otrivine nasal spray suitable for children?

No — Otrivine Adult Metered Dose Nasal Spray (0.1% xylometazoline) is not suitable for children under 12 years of age. There are separate Otrivine formulations designed for children, containing a lower concentration of xylometazoline (0.05%). Always check the product label carefully and choose the formulation appropriate for the child's age. Our baby and toddler range may have suitable options for younger children's symptoms.

What is the latest guidance on using nasal decongestant sprays in the UK?

Current NHS and MHRA guidance recommends that topical nasal decongestants like xylometazoline should be used for no more than 7 consecutive days to avoid rebound congestion. For persistent or recurrent nasal congestion, particularly if linked to allergies, healthcare professionals may recommend intranasal corticosteroid sprays as a longer-term option. Always follow the instructions in the patient information leaflet and consult a pharmacist or GP if symptoms do not improve.

How Should You Use Otrivine Adult Metered Dose Nasal Spray?

Using this spray correctly makes a real difference to how well it works. Before you start, blow your nose gently to clear the nasal passages as much as possible. If it's a new bottle, you'll need to prime the pump first by pressing it a few times until a fine mist appears.

Follow these steps each time you use the spray:

What Is the Correct Dose of Otrivine Adult Metered Dose Nasal Spray?

The dose depends on your age. This product is specifically formulated for adults and young people aged 12 and over. Never use this spray in children under 12 — a lower-strength formulation exists for younger age groups.

The table below summarises the recommended dosing:

When Is the Best Time to Use Otrivine Adult Metered Dose Nasal Spray?

There's no single "best" time — it really depends on when your congestion is most troublesome. Many people find it most helpful first thing in the morning, when nasal passages tend to feel most blocked after a night of lying down. Using it before bed can also help you breathe more comfortably through the night and improve sleep quality.

If you're using it during the day, try to space doses evenly apart. Avoid using the spray immediately before lying down flat, as this can affect how the medicine distributes in the nasal passages.

How Long Can You Use Otrivine Adult Metered Dose Nasal Spray For?

This spray is intended for short-term use only. Do not use it for more than 7 consecutive days. Using it beyond this period increases the risk of rebound congestion — a condition where the nasal passages become more congested when you stop using the spray, creating a cycle that can be difficult to break.

If your symptoms have not improved after 7 days, or if they worsen at any point, stop using the spray and speak to your GP. They can investigate whether there is an underlying cause for your persistent congestion and recommend appropriate treatment.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Otrivine Adult Metered Dose Nasal Spray?

Most people tolerate Otrivine well when used as directed, but some do experience mild side effects, particularly in the nasal passages. These are usually temporary and settle quickly after use.

  • Burning or stinging sensation inside the nose immediately after spraying
  • Nasal dryness or irritation
  • Increased nasal secretions (runny nose) shortly after use
  • Sneezing

What Are the Less Common Side Effects of Otrivine Adult Metered Dose Nasal Spray?

Less frequently, some people experience side effects that go beyond the nose. These are more likely if the spray is used more often than recommended or for longer than 7 days.

  • Headache
  • Nausea
  • Palpitations or a faster-than-normal heartbeat
  • Insomnia or restlessness, particularly if used late at night
  • Rebound congestion (rhinitis medicamentosa) — the nose becomes more blocked when you stop using the spray after prolonged use

What Are the Serious Side Effects of Otrivine Adult Metered Dose Nasal Spray?

Serious side effects are rare but can occur, particularly in people with pre-existing cardiovascular conditions or those who use the spray excessively. If you notice any of the following, stop using the spray immediately and seek urgent medical attention:

  • Significant increase in blood pressure
  • Chest pain or tightness
  • Severe or irregular heartbeat
  • Difficulty breathing unrelated to nasal congestion
  • Severe allergic reaction — including rash, swelling of the face, lips, or throat, or difficulty swallowing

What Should You Do If You Experience Side Effects of Otrivine Nasal Spray?

For mild side effects such as nasal dryness or stinging, no specific treatment is usually needed — they tend to resolve on their own. Reducing the frequency of use or ensuring you're using the correct technique can help minimise irritation. If you develop rebound congestion after stopping the spray, speak to your GP, who may recommend a gradual withdrawal approach or a switch to a corticosteroid nasal spray.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps improve medicine safety for everyone.

Can Otrivine Nasal Spray Interact With Other Medicines?

Yes — there are some important interactions to be aware of. Xylometazoline should not be used alongside monoamine oxidase inhibitors (MAOIs), as this combination can cause a dangerous rise in blood pressure. A 14-day washout period after stopping MAOIs is recommended before using this spray. Tricyclic antidepressants (such as amitriptyline) may also enhance the cardiovascular effects of xylometazoline. Using Otrivine alongside other sympathomimetic medicines — including some oral cold and flu remedies — may have additive effects. Always tell your pharmacist about all medicines you are currently taking before starting Otrivine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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