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Optrex Infected Eye Drops 0.5%

Optrex Infected Eye Drops 0.5%

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  • ✔️ Treats acute bacterial conjunctivitis in adults and children
  • ✔️ Contains chloramphenicol 0.5% — clinically proven antibiotic
  • ✔️ Visible improvement typically within 48 hours of starting
  • ✔️ Suitable for children aged 2 years and over
  • ✔️ Available OTC — no prescription required

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What Are Optrex Infected Eye Drops?

 

If your eye is red, sticky, and uncomfortable, bacterial conjunctivitis is one of the most likely culprits. Optrex infected eye drops contain chloramphenicol 0.5% — a well-established antibiotic that has been used to treat eye infections for decades. Available over the counter from registered UK pharmacies, this product offers a clinically recognised treatment option for adults and children aged 2 years and over, without the need for a GP appointment. You can browse our full range of eye care products if you need additional support for your eye health.

Bacterial conjunctivitis is extremely common. It causes the white of the eye to appear pink or red, often with a yellow or green discharge that can cause the eyelids to stick together — particularly in the morning. It can affect one or both eyes and spreads easily through direct contact. Treating it promptly with the right antibiotic drops helps reduce the duration of symptoms and limits the risk of passing the infection to others.

 

How Do Optrex Infected Eye Drops Work?

 

Chloramphenicol, the active ingredient in these drops, is a broad-spectrum antibiotic. It works by interfering with bacterial protein synthesis — essentially stopping bacteria from producing the proteins they need to grow and reproduce. Without those proteins, the bacteria cannot survive, and the infection clears. Here is a simple breakdown of the mechanism:

  • Chloramphenicol penetrates the eye tissue after instillation
  • It binds to the 50S ribosomal subunit of susceptible bacteria
  • This blocks peptidyl transferase activity, halting protein production
  • Bacteria are unable to replicate and the infection resolves

Because chloramphenicol is bacteriostatic (it stops bacteria multiplying rather than killing them outright), your immune system does the final work of clearing the remaining bacteria. This is why completing the full course of treatment matters, even if your eye starts to look better after a day or two.

 

Who Should Use Optrex Infected Eye Drops?

 

These drops are intended for people with acute bacterial conjunctivitis — not viral conjunctivitis, allergic conjunctivitis, or other eye conditions. If you are unsure what type of eye problem you have, speak to a pharmacist before starting treatment. They are suitable for:

  • Adults aged 18 and over with bacterial conjunctivitis
  • Children aged 2 years and over (under adult supervision)
  • People who need a short-term antibiotic eye treatment without a prescription
  • Those who have previously been diagnosed with bacterial conjunctivitis and recognise the symptoms

They are not suitable for people with a known history of blood disorders, aplastic anaemia, or hypersensitivity to chloramphenicol. Pregnant or breastfeeding women should seek medical advice before use. If symptoms do not improve within 48 hours, or worsen at any point, stop using the drops and consult a healthcare professional.

 

How Do Optrex Infected Eye Drops Compare to Alternatives?

 

Feature Optrex Infected Eye Drops 0.5% Golden Eye Chloramphenicol 0.5%
Active ingredient Chloramphenicol 0.5% Chloramphenicol 0.5%
Suitable age 2 years and over 2 years and over
Prescription required No (OTC) No (OTC)
Available format Eye drops Eye drops and eye ointment

 

How Should You Store Optrex Infected Eye Drops?

 

Proper storage is important to maintain the effectiveness of the drops. Keep them below 25°C and away from direct sunlight. Once opened, the bottle must be discarded after four weeks — even if there is solution remaining — to reduce the risk of contamination and secondary infection. Do not store in the fridge unless specifically instructed to do so on the packaging.

If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting. Contact lens wear is generally not recommended during an active eye infection. For other eye health products and accessories, take a look at our eye care collection.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Optrex Infected Eye Drops 0.5% specifications
Treatment category Bacterial conjunctivitis
Mechanism of action Inhibits bacterial protein synthesis via 50S ribosomal subunit binding
Effective against Susceptible gram-positive and gram-negative bacteria
Suitable for Adults and children aged 2 years and over
Active ingredient Chloramphenicol 0.5%
Pack size 10 ml
Strength 0.5% w/v
UK classification Pharmacy (P) medicine
Drug class Broad-spectrum antibiotic
Preparation Sterile aqueous eye drops
Route of administration Ophthalmic (topical)

Specifications of Optrex Infected Eye Drops 0.5%

 

What Is Optrex Infected Eye Drops 0.5% and What Is It Used For?

 

Optrex Infected Eye Drops 0.5% is a topical antibiotic preparation used to treat acute bacterial conjunctivitis — a common infection of the conjunctiva (the thin membrane covering the white of the eye and the inner eyelids). The active ingredient, chloramphenicol, is effective against a wide range of bacteria commonly responsible for eye infections, including Staphylococcus aureus and Haemophilus influenzae. It is classified as a Pharmacy (P) medicine in the UK, meaning it can be purchased without a prescription but only from a registered pharmacy, where a pharmacist can confirm it is appropriate for you.

Symptoms of bacterial conjunctivitis typically include redness, a gritty or burning sensation, and a sticky yellow or green discharge. Unlike viral conjunctivitis, which usually resolves on its own, bacterial conjunctivitis often benefits from antibiotic treatment to speed recovery and reduce the risk of spreading the infection to others or to the other eye.

 

What Do You Need to Know Before Using Optrex Infected Eye Drops?

 

Before using these drops, it is important to check whether they are suitable for you. Do not use Optrex Infected Eye Drops if any of the following apply:

  • You are allergic to chloramphenicol or any other ingredient in the product
  • You have a personal or family history of blood disorders, including aplastic anaemia
  • You are pregnant or breastfeeding (seek medical advice first)
  • The person being treated is under 2 years of age
  • You have a fungal or viral eye infection (e.g. herpes simplex keratitis)
  • You wear contact lenses (remove before use and do not reinsert during infection)

There are no significant drug interactions known at ophthalmic doses. However, if you are using any other eye drops or eye ointments, allow at least five minutes between applications. If you are using both drops and an ointment, always apply the drops first. If you have any concerns, speak to your pharmacist — you can also explore our first aid range for additional minor ailment support.

 

How Should You Use Optrex Infected Eye Drops?

 

Always follow the instructions in the patient information leaflet supplied with the product. The standard dosage for adults and children aged 2 and over is as follows:

  1. Wash your hands thoroughly with soap and water before handling the bottle
  2. Tilt your head back slightly and look up
  3. Gently pull down your lower eyelid to create a small pocket
  4. Hold the dropper above the eye and instil 1–2 drops into the pocket
  5. Close your eye gently for one to two minutes — do not blink vigorously
  6. Press lightly on the inner corner of your eye (nasolacrimal occlusion) to reduce systemic absorption
  7. Repeat in the other eye if both are affected
  8. Replace the cap immediately after use
Indication Age Group Dose Frequency
Bacterial conjunctivitis Adults and children aged 2+ 1–2 drops per affected eye Every 2 hours for 2 days, then every 4 hours for 3 days
Bacterial conjunctivitis Under 2 years Not recommended

 

What Are the Possible Side Effects of Optrex Infected Eye Drops?

 

Like all medicines, Optrex Infected Eye Drops can cause side effects, although not everyone experiences them. Most side effects are mild and localised to the eye.

Common side effects

  • Transient stinging or burning immediately after application
  • Temporary blurred vision (avoid driving until vision clears)
  • Mild eye irritation or watering

Less common side effects

  • Localised allergic reaction (redness, swelling, or itching worsening after use)
  • Superficial punctate keratitis (tiny erosions on the corneal surface) — rare

Although extremely rare with topical use, chloramphenicol has been associated with serious blood disorders including aplastic anaemia. If you notice unusual bruising, bleeding, or feel unusually tired during or after treatment, seek medical advice promptly. Stop using the drops and contact a healthcare professional if your symptoms worsen or do not improve within 48 hours of starting treatment.

 

How Should You Store Optrex Infected Eye Drops?

 

  • Store below 25°C in a dry place, away from direct sunlight and heat
  • Keep out of the reach and sight of children
  • Do not use after the expiry date printed on the bottle and carton
  • Discard the bottle four weeks after first opening, even if solution remains
  • Do not refrigerate unless the packaging specifically states otherwise
  • Do not share the bottle with anyone else — this reduces the risk of cross-contamination

If you are managing multiple minor health conditions alongside an eye infection, you may find it helpful to explore our allergy and hay fever range, as allergic conjunctivitis can sometimes be confused with the bacterial form and requires a different treatment approach entirely.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Optrex infected eye drops online in the UK?

You can buy Optrex Infected Eye Drops 0.5% directly from Cured Pharmacy, a GPhC-registered online pharmacy. No prescription is needed, but a pharmacist will check the product is suitable for you before your order is dispatched. Browse our full eye care collection for related products.

How do Optrex infected eye drops work in the eye?

The active ingredient, chloramphenicol 0.5%, is a broad-spectrum antibiotic that penetrates the eye tissue and binds to the 50S ribosomal subunit of bacteria. This stops the bacteria from producing the proteins they need to survive and multiply. Your immune system then clears the remaining bacteria, resolving the infection over the course of treatment.

How do I use Optrex infected eye drops step by step?

Wash your hands first, then tilt your head back and gently pull down your lower eyelid to form a small pocket. Instil one to two drops into the pocket, close your eye gently for one to two minutes, and press lightly on the inner corner of your eye. Replace the cap immediately and avoid touching the dropper tip to your eye or any surface.

How often should I use Optrex infected eye drops each day?

For the first two days, apply one to two drops every two hours during waking hours. From day three to day five, reduce the frequency to every four hours. Always complete the full five-day course, even if your eye looks and feels better before then.

How long does it take for Optrex infected eye drops to work?

Most people notice a visible improvement in redness, discharge, and discomfort within 48 hours of starting treatment. If there is no improvement after 48 hours, or if symptoms worsen at any point, stop using the drops and consult a pharmacist or GP. The full course should still be completed once improvement begins.

Can children use Optrex infected eye drops?

Yes — Optrex Infected Eye Drops are suitable for children aged 2 years and over, used under adult supervision. They must not be used in babies or children under 2 years of age. If you are unsure whether the product is appropriate for your child, speak to a pharmacist or GP before use.

What are the side effects of Optrex infected eye drops?

The most common side effects are temporary stinging, burning, or blurred vision immediately after applying the drops — these usually pass within a few minutes. Less commonly, some people experience localised allergic reactions such as increased redness or swelling. Although extremely rare with topical use, chloramphenicol has been associated with serious blood disorders; seek medical advice if you notice unusual bruising or fatigue.

Who should not use Optrex infected eye drops?

Do not use these drops if you have a known allergy to chloramphenicol, a personal or family history of aplastic anaemia or blood disorders, or if the person being treated is under 2 years old. Pregnant or breastfeeding women should seek medical advice before use. They are also not suitable for viral or fungal eye infections.

What happens if I miss a dose of Optrex infected eye drops?

If you miss a scheduled dose, apply the drops as soon as you remember. However, if it is nearly time for your next dose, simply skip the missed one and carry on with your regular schedule. Do not apply a double dose to make up for a missed one, as this will not speed recovery and may increase the risk of irritation.

Can I wear contact lenses while using Optrex infected eye drops?

No — you should remove contact lenses before applying the drops and not reinsert them during an active eye infection. Contact lens wear during bacterial conjunctivitis can worsen the infection and delay healing. Wait until the infection has fully cleared and your eye care professional has confirmed it is safe to resume lens wear.

What are alternatives to Optrex infected eye drops?

The main OTC alternative is chloramphenicol 0.5% eye drops sold under other brand names, such as Golden Eye drops. Golden Eye also offers a 1% chloramphenicol eye ointment, which some people find easier to apply at night. Your pharmacist can help you decide which format suits you best — you can also explore our wider eye care range for other options.

How long can I use Optrex infected eye drops for?

The recommended treatment course is five days. You should not use these drops for longer than five days without seeking medical advice. If your symptoms have not resolved by the end of the course, a GP may need to assess whether a different antibiotic or further investigation is required.

Is bacterial conjunctivitis contagious, and how can I stop spreading it?

Yes, bacterial conjunctivitis is highly contagious and spreads easily through direct contact with infected discharge or contaminated surfaces. Wash your hands frequently, avoid touching your eyes, do not share towels or pillowcases, and avoid close contact with others until the infection has cleared. Starting antibiotic treatment promptly helps reduce the period of contagiousness.

What is the difference between bacterial and viral conjunctivitis?

Bacterial conjunctivitis typically produces a thick yellow or green discharge and often causes the eyelids to stick together, particularly in the morning. Viral conjunctivitis usually produces a watery discharge and is often associated with a cold or upper respiratory infection. Antibiotic drops like Optrex Infected Eye Drops are only effective against bacterial conjunctivitis — viral conjunctivitis generally resolves on its own without antibiotic treatment.

Are there any recent studies on chloramphenicol eye drops for conjunctivitis?

Chloramphenicol eye drops remain a well-established first-line OTC treatment for bacterial conjunctivitis in the UK, supported by longstanding clinical evidence and NHS guidance. Research continues to confirm their effectiveness against common causative bacteria, though antibiotic stewardship guidance encourages confirming a bacterial cause before treatment where possible. Your pharmacist can help you assess whether antibiotic drops are appropriate for your specific symptoms.

How Should You Use Optrex Infected Eye Drops?

Using these drops correctly makes a real difference to how quickly your infection clears. Always wash your hands thoroughly before and after handling the bottle, and never allow the dropper tip to touch your eye, eyelid, or any other surface — this prevents contamination of the remaining solution.

What Is the Correct Dose of Optrex Infected Eye Drops?

The dose varies slightly depending on the stage of treatment. During the first two days, more frequent application is needed to establish adequate antibiotic levels in the eye tissue. From day three onwards, the frequency reduces as the infection begins to respond.

When Is the Best Time to Use Optrex Infected Eye Drops?

There is no single "best" time of day — what matters most is maintaining consistent intervals between doses throughout your waking hours. Space your doses as evenly as possible across the day to keep a steady level of antibiotic in the eye. If you are also using an eye ointment at night, apply the drops during the day and the ointment at bedtime, leaving at least five minutes between different eye preparations.

Remove contact lenses before each application and wait at least 15 minutes before reinserting — though ideally, avoid lens wear entirely until the infection has fully resolved.

How Long Can You Use Optrex Infected Eye Drops For?

The standard treatment course is five days. Do not use the drops for longer than five days without medical advice, even if symptoms persist. If your eye has not improved within 48 hours of starting treatment, or if symptoms worsen at any point, stop using the drops and consult a pharmacist or GP promptly. Once opened, the bottle must be discarded after four weeks regardless of how much solution remains.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Optrex Infected Eye Drops?

Most people tolerate Optrex Infected Eye Drops well, and side effects are generally mild and short-lived. The most frequently reported effects are localised to the eye and occur immediately after applying the drops.

  • Transient stinging or burning sensation in the eye
  • Temporary blurred vision lasting a few minutes after application
  • Mild watering or tearing of the eye
  • A brief feeling of grittiness or discomfort

What Are the Less Common Side Effects of Optrex Infected Eye Drops?

Some people may experience reactions that are less common but still worth being aware of. If any of the following occur, stop using the drops and seek advice from a pharmacist or GP.

  • Increased redness, swelling, or itching of the eye or eyelid (possible allergic reaction)
  • Superficial punctate keratitis — tiny erosions on the surface of the cornea (rare)
  • Persistent irritation that does not settle within a few minutes of application

What Are the Serious Side Effects of Optrex Infected Eye Drops?

Although extremely rare with topical ophthalmic use, chloramphenicol has been associated with serious blood disorders, including aplastic anaemia — a condition where the bone marrow stops producing enough blood cells. The risk from eye drops is considered very low compared to systemic (oral or injectable) chloramphenicol, but it is important to be aware of the warning signs. Seek urgent medical attention if you notice unusual bruising or bleeding, extreme fatigue, frequent infections, or pallor during or after treatment.

What Should You Do If You Experience Side Effects?

For mild, transient effects such as stinging or blurred vision, no action is usually needed — these typically resolve within a few minutes. If you experience a worsening allergic reaction, persistent eye pain, or any systemic symptoms such as unusual bruising or fatigue, stop using the drops immediately and contact your GP or call NHS 111. Do not restart treatment without medical guidance.

If your eye symptoms worsen or do not improve within 48 hours of starting treatment, this may indicate that the infection is not bacterial in origin, or that the causative bacteria are not susceptible to chloramphenicol. In either case, a healthcare professional should reassess your condition.

Can Optrex Infected Eye Drops Interact With Other Medicines?

At the low concentrations used in eye drops, chloramphenicol is not known to cause clinically significant interactions with other medicines. However, if you are using other eye drops or eye ointments at the same time, allow at least five minutes between applications to prevent dilution and ensure each product is properly absorbed. Always inform your pharmacist of any other medicines you are taking, including over-the-counter products.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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