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Nuromol Dual Action Pain Relief 200/500mg - 16 Tablets

Nuromol Dual Action Pain Relief 200/500mg - 16 Tablets

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  • ✔️ Combines ibuprofen and paracetamol for dual-mechanism pain relief
  • ✔️ Relieves headaches, back pain, dental pain, and period pain
  • ✔️ Two active ingredients target pain from different pathways simultaneously
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Convenient 16-tablet pack, no prescription required

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What Is Nuromol Dual Action Pain Relief?

 

Living with pain — whether it's a throbbing headache, nagging back ache, or dental discomfort — can make even the simplest tasks feel impossible. Nuromol dual action pain relief is a licensed over-the-counter tablet that combines two well-established analgesics, ibuprofen 200mg and paracetamol 500mg, in a single dose. Rather than choosing between one or the other, you get both working together. For anyone looking for effective relief from everyday pain, you can browse our full pain relief collection to find the right option for your needs.

Each pack contains 16 tablets, making it a practical choice to keep at home or in your bag. It's available without a prescription for adults and young people aged 12 and over, and at £5.25 it represents straightforward value for a dual-ingredient product.

 

How Does Nuromol Work to Relieve Pain?

 

The reason Nuromol is considered a dual action tablet is that its two active ingredients target pain through genuinely different pathways. That's not marketing language — it's pharmacology. Here's how each ingredient contributes:

  • Ibuprofen 200mg — a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting cyclo-oxygenase (COX) enzymes, reducing the production of prostaglandins. Prostaglandins are chemical messengers that sensitise nerve endings and promote inflammation, so blocking them reduces both pain and swelling.
  • Paracetamol 500mg — acts centrally within the brain and spinal cord to raise the pain threshold. Its exact mechanism is still being studied, but it is thought to modulate endocannabinoid pathways and inhibit a COX variant in the central nervous system.
  • Combined effect — because the two ingredients work differently, they complement each other. Clinical evidence suggests that combining ibuprofen and paracetamol at standard doses can provide greater pain relief than either drug alone at the same dose.

The result is a tablet that tackles pain from more than one angle — peripheral inflammation and central pain signalling — without requiring a prescription.

 

Who Is Nuromol Suitable For?

 

Nuromol is designed for adults and young people aged 12 years and over who need short-term relief from mild to moderate pain. It's particularly useful when a single-ingredient painkiller hasn't quite done the job. That said, it isn't right for everyone, so it's worth checking the list below before you buy.

Nuromol may be suitable if you:

  • Are aged 12 or over and weigh at least 40kg
  • Need relief from headaches, dental pain, period pain, back pain, or muscular aches
  • Have no known allergy to ibuprofen, aspirin, or paracetamol
  • Are not currently taking other ibuprofen- or paracetamol-containing medicines
  • Do not have active stomach ulcers, severe kidney disease, or severe liver impairment

 

How Does Nuromol Compare to Taking Ibuprofen or Paracetamol Separately?

 

Feature Nuromol 200/500mg Ibuprofen 200mg alone Paracetamol 500mg alone
Active ingredients Ibuprofen + Paracetamol Ibuprofen only Paracetamol only
Anti-inflammatory action Yes Yes No
Central pain relief Yes Limited Yes
Suitable for stomach-sensitive patients Take with food — caution advised Take with food — caution advised Generally well tolerated
Prescription required No (OTC) No (OTC) No (OTC)

 

How Should You Store Nuromol and Is It Clinically Appropriate for You?

 

Store Nuromol below 25°C in a dry place, away from direct sunlight, and always keep it out of the reach and sight of children. Do not use the tablets after the expiry date printed on the pack. If you're unsure whether Nuromol dual action pain relief is the right choice for your situation — for example, if you have a long-term health condition, are pregnant, or are already taking regular medication — speak to your pharmacist before starting. If you're managing symptoms alongside other health concerns, our vitamins and supplements range may also be worth exploring as part of a broader wellness approach.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Nuromol Dual Action Pain Relief 200/500mg - 16 Tablets specifications
Treatment category Pain relief / Analgesic
Mechanism of action COX enzyme inhibition (ibuprofen) + central pain threshold modulation (paracetamol)
Effective for Headache, dental pain, period pain, back pain, muscular aches, cold and flu symptoms
Suitable for Adults and young people aged 12 and over
Active ingredients Ibuprofen 200mg, Paracetamol 500mg
Pack size 16 tablets
Strengths Ibuprofen 200mg / Paracetamol 500mg per tablet
UK classification General Sale List (GSL)
Drug class NSAID + Analgesic combination
Preparation Film-coated tablet
Route of administration Oral

Specifications of Nuromol Dual Action Pain Relief 200/500mg - 16 Tablets

 

What Is Nuromol and What Is It Used For?

 

Nuromol Dual Action Pain Relief 200/500mg tablets contain two active ingredients: ibuprofen 200mg and paracetamol 500mg. It is used for the short-term relief of mild to moderate pain in adults and young people aged 12 and over. Conditions it can help with include headaches, migraine headaches, dental pain, period pain (dysmenorrhoea), back pain, rheumatic and muscular pain, and the feverishness and aches associated with colds and flu. If you're also dealing with cold and flu symptoms alongside pain, our cold and flu range has additional options to consider.

 

What Do You Need to Know Before Using Nuromol?

 

Do not take Nuromol if any of the following apply to you:

  • You are allergic to ibuprofen, paracetamol, aspirin, or any other NSAID
  • You have or have had a stomach ulcer, perforation, or gastrointestinal bleeding
  • You are in the third trimester of pregnancy (after 28 weeks)
  • You have severe heart failure, severe kidney disease, or severe liver disease
  • You are under 12 years of age
  • You are already taking another product containing ibuprofen or paracetamol

Talk to your doctor or pharmacist before taking Nuromol if you have asthma, high blood pressure, a history of heart disease, Crohn's disease, or ulcerative colitis. Caution is also needed if you regularly drink alcohol, as this increases the risk of liver damage from paracetamol and gastrointestinal bleeding from ibuprofen.

Medicines that may interact with Nuromol include:

  • Anticoagulants such as warfarin — increased bleeding risk
  • Aspirin and other NSAIDs — increased risk of side effects
  • Lithium — ibuprofen can raise lithium blood levels
  • Methotrexate — ibuprofen may increase methotrexate toxicity
  • Antihypertensives (blood pressure medicines) — ibuprofen may reduce their effect
  • Selective serotonin reuptake inhibitors (SSRIs) — increased gastrointestinal bleeding risk

 

How Should You Use Nuromol Tablets?

 

Always take Nuromol exactly as described in this leaflet or as directed by your pharmacist. Swallow the tablets whole with a full glass of water. Taking them with food or milk can help reduce the chance of stomach upset.

  1. Check you are not already taking any other ibuprofen- or paracetamol-containing product.
  2. Take 1 or 2 tablets with a full glass of water.
  3. If possible, take with food or milk to protect your stomach.
  4. Wait at least 4 hours before taking your next dose.
  5. Do not take more than 3 doses (6 tablets) in any 24-hour period.
  6. Do not use for more than 3 days without speaking to a doctor or pharmacist.
Age Group Dose Frequency Maximum in 24 hours
Adults and young people aged 12+ 1–2 tablets Every 4–6 hours 6 tablets (3 doses)
Children under 12 Not suitable — do not use

 

What Are the Possible Side Effects of Nuromol?

 

Like all medicines, Nuromol can cause side effects, although not everyone gets them. If you experience any serious side effect — such as signs of an allergic reaction (swelling of the face, lips, or throat, difficulty breathing, or a severe skin rash) — stop taking the tablets immediately and seek urgent medical attention.

Common side effects (may affect up to 1 in 10 people):

  • Nausea or feeling sick
  • Indigestion or heartburn
  • Stomach discomfort or abdominal pain
  • Diarrhoea

Less common side effects (may affect up to 1 in 100 people):

  • Dizziness or headache
  • Skin rash or itching
  • Raised liver enzymes (detected on blood tests)
  • Fluid retention (oedema)
  • Worsening of asthma symptoms in susceptible individuals

If you are concerned about a side effect or it persists, contact your pharmacist or GP. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

 

How Should You Store Nuromol Tablets?

 

Correct storage helps maintain the quality and safety of your tablets. Follow these instructions:

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and moisture
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

If you're managing multiple health products at home, it's worth keeping a dedicated medicine storage area. You might also find our first aid range useful for building a complete home health kit.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Nuromol dual action pain relief online in the UK?

You can buy Nuromol Dual Action Pain Relief 200/500mg 16 tablets directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter medicine. Simply add it to your basket and it will be dispatched to your door. You can also browse our wider pain relief collection for related products.

How does Nuromol work in the body?

Nuromol contains ibuprofen 200mg and paracetamol 500mg, which work through two distinct mechanisms to relieve pain. Ibuprofen inhibits COX enzymes to reduce prostaglandin production and inflammation at the site of pain, while paracetamol acts centrally in the brain and spinal cord to raise the pain threshold. Together, they provide broader pain relief than either ingredient alone at the same dose.

How do I take Nuromol tablets step by step?

Take 1 to 2 tablets with a full glass of water, ideally with food or milk to reduce the risk of stomach upset. Wait at least 4 hours before taking your next dose, and do not exceed 6 tablets (3 doses) in any 24-hour period. Do not take alongside any other product containing ibuprofen or paracetamol.

What is the maximum daily dose of Nuromol for adults?

The maximum dose for adults and young people aged 12 and over is 6 tablets in any 24-hour period, taken as no more than 3 separate doses. Each dose should be spaced at least 4 hours apart. Exceeding this limit increases the risk of serious side effects, including liver damage from paracetamol and gastrointestinal bleeding from ibuprofen.

What are the side effects of Nuromol tablets?

Common side effects include nausea, indigestion, stomach discomfort, and diarrhoea. Less commonly, some people experience dizziness, skin rash, fluid retention, or worsening of asthma symptoms. If you notice signs of a serious allergic reaction — such as facial swelling, difficulty breathing, or a severe rash — stop taking Nuromol immediately and seek urgent medical help.

Who should not take Nuromol tablets?

Nuromol is not suitable for children under 12 years of age, people with a known allergy to ibuprofen, aspirin, or paracetamol, or those with active stomach ulcers or severe kidney, liver, or heart failure. It should also be avoided by anyone in the third trimester of pregnancy (after 28 weeks). Always check with your pharmacist if you are unsure whether it is appropriate for you.

Can I take Nuromol if I am pregnant or breastfeeding?

Nuromol should not be taken during the third trimester of pregnancy (after 28 weeks) as ibuprofen can harm the unborn baby. During the first and second trimesters, use should only be on medical advice. If you are breastfeeding, speak to your pharmacist or GP before taking Nuromol, as small amounts of ibuprofen can pass into breast milk.

Can I take Nuromol with other painkillers or medicines?

Do not take Nuromol with any other product containing ibuprofen or paracetamol, as this risks exceeding safe daily limits for both ingredients. Nuromol may also interact with anticoagulants such as warfarin, lithium, methotrexate, antihypertensives, and SSRIs. Always tell your pharmacist about all medicines you are currently taking before starting Nuromol.

What happens if I miss a dose of Nuromol?

If you miss a dose and are still in pain, take your next dose as soon as you remember — provided at least 4 hours have passed since your last dose. Do not double up to make up for a missed dose. Nuromol is taken as needed for pain relief rather than on a strict schedule, so missing a dose is not usually a concern.

How long can you take Nuromol for?

Nuromol is intended for short-term use only — no more than 3 days without consulting a doctor or pharmacist. If your pain persists beyond 3 days, worsens, or is accompanied by other symptoms, you should seek professional medical advice rather than continuing to self-medicate. Long-term use of ibuprofen-containing products carries risks including gastrointestinal and cardiovascular complications.

Is Nuromol suitable for children?

No — Nuromol Dual Action Pain Relief 200/500mg tablets are not suitable for children under 12 years of age. For pain relief in younger children, age-appropriate paracetamol or ibuprofen suspensions are available. You can explore suitable options in our baby and toddler range for younger patients.

What are the alternatives to Nuromol for pain relief?

Alternatives include taking ibuprofen 200mg and paracetamol 500mg as separate tablets (staggered or together), or using other combination analgesics available over the counter. For some types of pain, topical ibuprofen gels or heat patches may also be appropriate. Speak to your pharmacist about which option suits your specific type of pain best.

Does Nuromol help with period pain?

Yes — Nuromol is licensed for the relief of period pain (dysmenorrhoea) in adults and young people aged 12 and over. The ibuprofen component is particularly effective for period pain because it reduces prostaglandin levels, which are responsible for uterine cramping. Take with food and follow the recommended dosage instructions on the pack.

Can I drink alcohol while taking Nuromol?

It is advisable to avoid or limit alcohol while taking Nuromol. Alcohol combined with ibuprofen increases the risk of gastrointestinal bleeding and stomach irritation, while alcohol combined with paracetamol raises the risk of liver damage — particularly if you drink regularly or in large amounts. If you have any concerns, speak to your pharmacist before taking this medicine.

What is the latest research on combining ibuprofen and paracetamol for pain?

Published clinical research, including studies referenced in NHS guidance, supports the use of ibuprofen and paracetamol in combination for greater analgesic efficacy than either drug alone at equivalent doses. The combination is widely used in post-operative and acute pain settings. For everyday OTC use, Nuromol dual action pain relief provides this evidence-based approach in a convenient single tablet format.

How Should You Use Nuromol Dual Action Pain Relief?

Nuromol tablets are taken orally with a full glass of water. To reduce the risk of stomach irritation — which can occur with ibuprofen-containing products — it is advisable to take each dose with food or a glass of milk.

What Is the Correct Dose of Nuromol?

The dose depends on your age. Nuromol is not suitable for children under 12 years of age under any circumstances. For adults and young people aged 12 and over, the dose is 1 to 2 tablets per dose, up to a maximum of 3 doses in 24 hours. Always use the lowest effective dose for the shortest time necessary.

When Is the Best Time to Use Nuromol?

Take Nuromol as soon as pain begins — early intervention tends to be more effective than waiting until pain becomes severe. If you are prone to stomach sensitivity, taking your dose with breakfast or a light meal is a sensible approach. Avoid taking it on an empty stomach where possible, particularly if you are taking multiple doses throughout the day.

There is no single "best" time of day for Nuromol — it is taken as needed rather than on a fixed schedule. The key is to maintain at least a 4-hour gap between doses and not to exceed the daily maximum.

How Long Can You Use Nuromol For?

Nuromol is intended for short-term use only. Do not take it for more than 3 consecutive days without speaking to a doctor or pharmacist. If your pain has not improved after 3 days, or if it worsens at any point, stop taking the tablets and seek medical advice. Prolonged use of ibuprofen-containing medicines without medical supervision carries risks including gastrointestinal complications and cardiovascular effects.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Nuromol?

Because Nuromol contains ibuprofen — a non-steroidal anti-inflammatory drug (NSAID) — gastrointestinal side effects are the most frequently reported. These are generally mild and often resolve on their own, particularly if you take the tablets with food.

  • Nausea or feeling sick
  • Indigestion or heartburn (dyspepsia)
  • Stomach pain or abdominal discomfort
  • Diarrhoea
  • Vomiting

What Are the Less Common Side Effects of Nuromol?

Less common side effects affect a smaller proportion of people but are still worth being aware of. If any of the following persist or concern you, contact your pharmacist or GP.

  • Dizziness or headache
  • Skin rash, itching, or hives (urticaria)
  • Fluid retention (oedema), particularly in the ankles or feet
  • Raised liver enzymes (usually detected incidentally on blood tests)
  • Worsening of asthma or breathlessness in susceptible individuals
  • Tinnitus (ringing in the ears) — rare but reported with ibuprofen

What Are the Serious Side Effects of Nuromol?

Serious side effects are uncommon when Nuromol is used at the recommended dose for a short period, but they can occur. Stop taking Nuromol immediately and seek urgent medical attention if you experience any of the following:

  • Signs of a severe allergic reaction — swelling of the face, lips, tongue, or throat; difficulty breathing; or a widespread skin rash
  • Black, tarry, or blood-streaked stools, or vomiting blood — these may indicate gastrointestinal bleeding
  • Chest pain, sudden shortness of breath, or weakness on one side of the body — possible cardiovascular events
  • Severe skin reactions such as Stevens-Johnson syndrome (blistering, peeling skin) — very rare
  • Signs of liver damage — yellowing of the skin or eyes (jaundice), dark urine, or severe upper abdominal pain

What Should You Do If You Experience Side Effects of Nuromol?

For mild side effects such as nausea or indigestion, try taking your next dose with food or milk. If side effects are persistent, worsening, or worrying, stop taking Nuromol and speak to your pharmacist or GP. You can also report suspected side effects directly to the Medicines and Healthcare products Regulatory Agency (MHRA) via the Yellow Card scheme at yellowcard.mhra.gov.uk — your report helps improve medicine safety for everyone.

Can Nuromol Interact With Other Medicines?

Yes — Nuromol can interact with a number of other medicines, which is why it is important to tell your pharmacist about everything you are currently taking. Key interactions include anticoagulants such as warfarin (increased bleeding risk), lithium (ibuprofen raises lithium plasma levels), methotrexate (increased toxicity risk), antihypertensive medicines (reduced blood pressure-lowering effect), SSRIs (increased gastrointestinal bleeding risk), and other NSAIDs or aspirin (additive side effects). Never take Nuromol alongside another product containing ibuprofen or paracetamol.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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