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Motusol Max 2.32% w/w Diclofenac Gel - 30g

Motusol Max 2.32% w/w Diclofenac Gel - 30g

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  • 5. Supports cardiovascular risk reduction
  • 6. Over 22 million patients treated with semaglutide-based therapies since 2018

  • ✔️ Targets muscle and joint pain directly at the source
  • ✔️ Contains 2.32% diclofenac for effective anti-inflammatory action
  • ✔️ Topical application reduces risk of stomach side effects
  • ✔️ Suitable for sports injuries, sprains, and localised joint pain
  • ✔️ Compact 30g tube — easy to use at home or on the go

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What Is Diclofenac Gel and How Does It Relieve Pain?

 

Muscle aches, stiff joints, and localised inflammation can make even simple daily tasks feel like a challenge. Motusol Max 2.32% w/w Diclofenac Gel offers targeted, topical relief — applied directly where it hurts, so you're not flooding your whole system with medication. It contains diclofenac diethylammonium as its active ingredient, a well-established non-steroidal anti-inflammatory drug (NSAID) used widely across the UK for musculoskeletal pain. At just £6.49 for a 30g tube, it's an accessible option for adults managing everyday pain. You can explore our full range of pain relief products if you're looking for additional options alongside this gel.

This gel is classified as a pharmacy (P) medicine in the UK, meaning it's available without a prescription but should be used with care. It's suitable for adults and adolescents aged 14 and over, and it's designed for short-term use on localised areas of the body.

 

How Does Motusol Max Diclofenac Gel Work in the Body?

 

Diclofenac gel works by inhibiting cyclo-oxygenase (COX-1 and COX-2) enzymes at the site of application. These enzymes are responsible for producing prostaglandins — the chemical messengers that trigger pain, swelling, and inflammation in your tissues. By blocking their production locally, the gel helps reduce discomfort without the need for oral medication.

  • Diclofenac penetrates the skin and underlying soft tissue after topical application.
  • It inhibits COX enzymes, reducing prostaglandin synthesis at the pain site.
  • Inflammation and associated swelling begin to reduce with regular use.
  • Systemic absorption is significantly lower than oral NSAIDs, reducing the risk of gastrointestinal side effects.

Because the gel acts locally rather than systemically, it's often a preferred choice for people who cannot tolerate oral NSAIDs due to stomach sensitivity.

 

Who Is Motusol Max Diclofenac Gel Suitable For?

 

This gel is intended for adults and adolescents aged 14 years and over who are experiencing localised musculoskeletal pain. It's particularly useful for people who want targeted relief without taking tablets. That said, it's not appropriate for everyone — always read the label and check with your pharmacist if you're unsure.

  • Adults with muscle strains or sprains from sport or physical activity
  • People with localised joint pain, such as knee or shoulder discomfort
  • Those who prefer topical treatment over oral pain relief
  • Individuals who experience stomach upset with oral NSAIDs

 

How Does Motusol Max Compare to Other Topical Pain Relief Gels?

 

Feature Motusol Max 2.32% Diclofenac Gel Ibuprofen Gel 5%
Active ingredient Diclofenac diethylammonium Ibuprofen
NSAID class Yes Yes
Application frequency 3–4 times daily 3–4 times daily
Suitable age 14 years and over 14 years and over
Systemic absorption Low Low

 

How Should You Store Motusol Max Diclofenac Gel?

 

Store Motusol Max below 25°C in a cool, dry place away from direct sunlight. Keep the tube tightly closed when not in use, and always keep it out of the reach and sight of children. Do not use the gel after the expiry date printed on the packaging. If you're browsing other topical treatments, our creams and ointments collection includes a range of options for skin and musculoskeletal conditions.

Do not freeze the gel, and avoid storing it in the bathroom where humidity and temperature fluctuations can affect the product's stability.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Motusol Max 2.32% w/w Diclofenac Gel - 30g specifications
Treatment category Muscle and joint pain relief
Active ingredient Diclofenac diethylammonium 2.32% w/w
Mechanism of action COX-1 and COX-2 enzyme inhibition; reduces prostaglandin synthesis
Drug class Non-steroidal anti-inflammatory drug (NSAID)
Preparation Topical gel
Route of administration Topical (cutaneous)
Strengths 2.32% w/w
Pack sizes 30g
Suitable for Adults and adolescents aged 14 years and over
UK classification Pharmacy (P) medicine

Specifications of Motusol Max 2.32% w/w Diclofenac Gel - 30g

 

What Is Motusol Max Diclofenac Gel and What Is It Used For?

 

Motusol Max 2.32% w/w Diclofenac Gel is a topical NSAID used to relieve pain and reduce inflammation in muscles and joints. It is indicated for the symptomatic relief of localised forms of soft tissue rheumatism, sprains, strains, and sports injuries in adults and adolescents aged 14 and over. The gel is applied directly to the skin over the affected area, allowing the active ingredient to work at the source of pain rather than throughout the body.

 

What Do You Need to Know Before Using Motusol Max Diclofenac Gel?

 

Before using this gel, it's important to check whether it's right for you. There are certain situations where you should not use it, and others where extra caution is needed.

Do not use this gel if you:

  • Are allergic to diclofenac, aspirin, ibuprofen, or any other NSAID
  • Are in the third trimester of pregnancy (weeks 28 onwards)
  • Have broken, infected, or inflamed skin at the application site
  • Are under 14 years of age
  • Have a history of asthma triggered by NSAIDs

Use with caution and speak to your pharmacist if you:

  • Are in the first or second trimester of pregnancy or are breastfeeding
  • Have kidney, liver, or heart problems
  • Are taking anticoagulants such as warfarin
  • Have a history of gastrointestinal problems

Known drug interactions:

  • Anticoagulants (e.g. warfarin) — systemic absorption is low, but caution is still advised
  • Other NSAIDs — avoid concurrent use of oral or topical NSAIDs unless directed by a doctor
  • Ciclosporin or methotrexate — diclofenac may affect their plasma levels if absorbed systemically

 

How Should You Use Motusol Max Diclofenac Gel Correctly?

 

Always use this gel exactly as directed on the label or as advised by your pharmacist. Do not apply more than instructed, and avoid applying to large areas of skin.

  1. Wash and dry the affected area before application.
  2. Squeeze a small amount of gel (approximately 2–4g, roughly the size of a 50p coin) onto your fingertips.
  3. Gently massage the gel into the skin over the painful area until fully absorbed.
  4. Wash your hands thoroughly after application, unless your hands are the area being treated.
  5. Do not cover the area with an airtight or occlusive dressing after applying.
  6. Avoid contact with eyes, mouth, and mucous membranes.
Indication Age Group Dose Frequency
Muscle strains and sprains Adults and adolescents (14+) 2–4g per application 3–4 times daily
Localised joint pain Adults and adolescents (14+) 2–4g per application 3–4 times daily
Children under 14 Not applicable Not recommended Not recommended

 

What Are the Possible Side Effects of Motusol Max Diclofenac Gel?

 

Like all medicines, this gel can cause side effects, although not everyone experiences them. Most side effects are localised to the skin at the application site and are mild in nature. If you're managing multiple health concerns, you might also find our first aid collection useful for minor injuries alongside this treatment.

Common side effects (may affect up to 1 in 10 people):

  • Skin redness or erythema at the application site
  • Itching or pruritus
  • Dry or flaking skin
  • A mild burning or stinging sensation after application

Less common side effects (may affect up to 1 in 100 people):

  • Contact dermatitis or eczema-like reaction
  • Localised swelling or oedema
  • Photosensitivity — increased sensitivity to sunlight at the treated area
  • Rash or urticaria

Serious allergic reactions (anaphylaxis) are rare but possible. Stop using the gel immediately and seek emergency medical help if you experience swelling of the face, lips, or throat, difficulty breathing, or a severe skin reaction.

 

How Should You Store Motusol Max Diclofenac Gel?

 

  • Store below 25°C in a cool, dry place.
  • Do not freeze.
  • Keep the tube tightly closed after each use.
  • Keep out of the reach and sight of children.
  • Do not use after the expiry date printed on the tube and carton.
  • Do not store in the bathroom or near sources of heat or direct sunlight.
  • Dispose of unused medicine responsibly — return to your local pharmacy for safe disposal.

If you're looking for other health products to support your wellbeing, browse our vitamins and supplements collection for options that may complement your recovery.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Motusol Max diclofenac gel online in the UK?

You can buy Motusol Max 2.32% w/w Diclofenac Gel directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. It is available without a prescription as an over-the-counter medicine for adults and adolescents aged 14 and over. Simply add it to your basket and complete a short health check at checkout to ensure it's suitable for you.

How does diclofenac gel work to relieve muscle and joint pain?

Diclofenac gel works by inhibiting COX-1 and COX-2 enzymes at the site of application, which reduces the production of prostaglandins — the chemicals responsible for pain and inflammation. When rubbed into the skin, it penetrates the tissue to act locally, meaning you get targeted relief without significant systemic effects. This makes it a useful option for people who want to avoid oral anti-inflammatory tablets.

How do I apply Motusol Max diclofenac gel step by step?

Start by washing and drying the affected area, then squeeze approximately 2–4g of gel onto your fingertips and gently massage it into the skin until fully absorbed. Wash your hands after application unless your hands are the area being treated, and avoid applying near your eyes or mouth. Do not cover the treated area with an airtight dressing.

How many times a day should I use Motusol Max diclofenac gel?

Apply Motusol Max gel three to four times daily to the affected area, spacing applications evenly throughout the day. Do not apply more than the recommended amount or use it on large areas of skin, as this can increase the risk of side effects. If your symptoms have not improved after 14 days, consult your pharmacist or GP.

What are the most common side effects of Motusol Max diclofenac gel?

The most common side effects are localised skin reactions at the application site, including redness, itching, dry skin, or a mild burning sensation. These are generally mild and resolve on their own once you stop using the gel. If you develop a more severe skin reaction, swelling, or difficulty breathing, stop use immediately and seek medical advice.

Who should not use Motusol Max diclofenac gel?

This gel is not suitable for people who are allergic to diclofenac, aspirin, ibuprofen, or any other NSAID. It should not be used during the third trimester of pregnancy, on broken or infected skin, or by children under 14 years of age. If you have asthma that is triggered by NSAIDs, speak to your doctor before using this product.

Can I use Motusol Max diclofenac gel during pregnancy?

Motusol Max diclofenac gel must not be used during the third trimester of pregnancy (from week 28 onwards) as NSAIDs can affect the foetal cardiovascular system and may delay labour. Use during the first and second trimesters should only be considered on medical advice, as the risks are not fully established. Always speak to your midwife, GP, or pharmacist before using any medicine during pregnancy.

How long can I use Motusol Max diclofenac gel for?

Motusol Max is intended for short-term use only — do not use it for more than 14 days without consulting a doctor or pharmacist. Prolonged use of topical NSAIDs may increase the risk of skin reactions and, in rare cases, systemic side effects. If your pain persists beyond two weeks, it's important to get a proper assessment of the underlying cause.

What happens if I accidentally get Motusol Max diclofenac gel in my eyes?

If the gel comes into contact with your eyes, rinse them immediately and thoroughly with clean, lukewarm water for several minutes. Do not rub your eyes, as this can worsen irritation. If discomfort, redness, or blurred vision persists after rinsing, seek medical attention promptly.

Can I use Motusol Max diclofenac gel alongside oral pain relief?

You should avoid using Motusol Max at the same time as other oral or topical NSAIDs (such as ibuprofen tablets or naproxen) unless specifically advised by a doctor, as this can increase the risk of side effects. Paracetamol is generally considered safe to use alongside topical diclofenac, but always check with your pharmacist first. Our pain relief collection includes a range of options your pharmacist can help you choose between.

What are the alternatives to Motusol Max diclofenac gel for joint pain?

Alternatives include other topical NSAIDs such as ibuprofen gel or ketoprofen gel, as well as oral pain relief medicines like paracetamol or ibuprofen tablets. For some types of joint pain, heat or cold therapy, physiotherapy, or rest may also be recommended alongside or instead of medication. Speak to your pharmacist to find the most appropriate option for your specific situation.

Does Motusol Max diclofenac gel interact with warfarin?

Although systemic absorption from topical diclofenac gel is low, there is a theoretical risk of interaction with anticoagulants such as warfarin. If you are taking warfarin or any other blood-thinning medicine, speak to your pharmacist or GP before using this gel. They may recommend monitoring your INR more closely during treatment.

Is Motusol Max diclofenac gel suitable for sports injuries?

Yes, Motusol Max is suitable for the relief of pain and inflammation associated with sports injuries such as sprains, strains, and muscle soreness in adults and adolescents aged 14 and over. It can be applied directly to the affected area after activity to help manage localised discomfort. Always ensure the skin is intact and undamaged before applying the gel.

What is the latest research on topical diclofenac gel for pain?

Clinical evidence supports the use of topical diclofenac as an effective treatment for localised musculoskeletal pain, with studies showing it provides meaningful pain relief with a lower risk of gastrointestinal side effects compared to oral NSAIDs. The NHS and NICE recognise topical NSAIDs as a first-line option for conditions such as osteoarthritis of the knee. Research continues to support their use in soft tissue injuries and localised inflammatory conditions.

Can I use Motusol Max diclofenac gel on my back?

Motusol Max can be applied to the lower back for localised muscle pain, provided the skin is intact and not broken or infected. However, it is less effective for deep-seated or widespread back pain, where oral treatment or physiotherapy may be more appropriate. If your back pain is severe, persistent, or accompanied by other symptoms, consult your GP for a full assessment. You might also find useful information in our first aid section for managing minor injuries at home.

How Should You Use Motusol Max Diclofenac Gel?

Using Motusol Max correctly ensures you get the most benefit while minimising the risk of side effects. Always apply the gel to clean, dry, intact skin — never on broken, infected, or inflamed areas. Follow these steps each time you use it:

Allow the gel to absorb fully before covering the area with clothing. If you accidentally get the gel in your eyes, rinse immediately with clean water and seek advice if irritation persists.

What Is the Correct Dose of Motusol Max Diclofenac Gel?

The correct dose depends on the size of the area being treated and the nature of your pain. As a general guide, 2–4g per application is appropriate for most localised areas. Do not apply to large areas of the body or use more than directed, as this increases the risk of systemic absorption and side effects.

When Is the Best Time to Use Motusol Max Diclofenac Gel?

There is no single "best" time of day to apply Motusol Max — what matters most is spacing your applications evenly throughout the day. Many people find it helpful to apply the gel after waking, at midday, in the late afternoon, and before bed, which naturally creates three to four applications spread across the day. Applying after gentle movement or a warm shower may also help the gel absorb more effectively into the tissue.

If you are using the gel for sports-related pain, applying it after activity — once the skin has cooled and is no longer sweating — is generally more effective than applying immediately before exercise.

How Long Can You Use Motusol Max Diclofenac Gel For?

Motusol Max is intended for short-term use only. Do not use it for more than 14 consecutive days without consulting a doctor or pharmacist. Most people notice an improvement in their symptoms within a few days of starting treatment, but if there is no improvement after 7 days, it is worth seeking advice to rule out an underlying condition that may need different management.

Long-term or excessive use of topical NSAIDs is not recommended, as it may increase the risk of skin reactions and, in rare cases, systemic side effects. If your pain is ongoing or recurring, speak to your GP about longer-term management strategies.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Motusol Max Diclofenac Gel?

Most people who use Motusol Max tolerate it well, and side effects are usually mild and confined to the area of skin where the gel has been applied. Because the gel acts locally rather than systemically, the risk of whole-body side effects is much lower than with oral NSAIDs.

  • Skin redness (erythema) at the application site
  • Itching or pruritus
  • Dry or flaking skin
  • A mild burning or stinging sensation immediately after application

What Are the Less Common Side Effects of Motusol Max Diclofenac Gel?

Less common reactions occur in fewer people but are still worth being aware of. If any of the following develop, stop using the gel and speak to your pharmacist or GP.

  • Contact dermatitis — an eczema-like reaction with redness, scaling, and itching
  • Localised swelling or oedema at the treated area
  • Photosensitivity — increased sensitivity to sunlight on the treated skin
  • Urticaria (hives) or a generalised skin rash
  • Blistering or peeling of the skin

What Are the Serious Side Effects of Motusol Max Diclofenac Gel?

Serious side effects from topical diclofenac are rare, but they can occur — particularly if the gel is used on large areas of skin, under occlusive dressings, or for prolonged periods. Systemic absorption in these circumstances may be higher than expected.

Seek emergency medical help immediately if you experience any of the following:

  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Difficulty breathing or wheezing
  • A severe or widespread skin reaction
  • Signs of a serious allergic reaction (anaphylaxis) such as dizziness, rapid heartbeat, or collapse

What Should You Do If You Experience Side Effects of Motusol Max Diclofenac Gel?

If you notice a mild skin reaction such as redness or itching, stop applying the gel to that area and allow the skin to recover. Wash the area gently with water to remove any remaining gel. For more persistent or worsening reactions, contact your pharmacist or GP for advice before continuing use.

You can also report suspected side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. This helps regulators monitor the safety of medicines in real-world use.

Can Motusol Max Diclofenac Gel Interact With Other Medicines?

Although systemic absorption from topical diclofenac is low, interactions with other medicines are still possible, particularly if the gel is used frequently or on large areas of skin. The following interactions are worth noting:

  • Anticoagulants (e.g. warfarin): Theoretical risk of enhanced anticoagulant effect — monitor closely and seek pharmacist advice.
  • Other NSAIDs (oral or topical): Concurrent use increases the risk of side effects — avoid unless directed by a doctor.
  • Ciclosporin or methotrexate: Diclofenac may affect plasma levels if absorbed systemically — use with caution.
  • Lithium: NSAIDs may increase lithium plasma concentrations — seek medical advice before use.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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