What is the best time to take Menopace Plus tablets?

The manufacturer recommends taking both tablets with your main meal. Taking them with food can also help reduce the chance of any mild stomach discomfort.

How long should I take Menopace Plus for?

Menopace Plus can be taken throughout the menopause transition, which may last several years. Speak to your GP or pharmacist if you are unsure how long to continue supplementation.

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MENOPACE PLUS 56 TABLETS

✔️ Supports bone health as oestrogen levels naturally decline
✔️ Provides soy isoflavones to help ease menopausal symptoms
✔️ Combines vitamins B6 and D for hormonal and immune support
✔️ Dual-tablet system targets menopause from two nutritional angles
✔️ Suitable for vegetarians and free from artificial colours

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What Are Menopace Plus Tablets and How Can They Help?

Menopause is a natural stage of life, but that doesn't mean it's always easy. Hot flushes, fatigue, mood changes, and disrupted sleep can all take a real toll on your day-to-day wellbeing. Menopace Plus tablets are a two-component daily food supplement designed specifically to support women during this transition, combining a broad-spectrum vitamin and mineral tablet with a separate isoflavone tablet. Together, they address some of the nutritional gaps that commonly arise during perimenopause and menopause. You can explore the full range of relevant products in our vitamins and supplements collection.

Each pack of Menopace Plus 56 Tablets contains 28 Menopace tablets and 28 isoflavone tablets — a 28-day supply. The formulation includes vitamins B6, B12, C, D, and E, alongside magnesium, zinc, folic acid, and standardised soy isoflavones. These nutrients are chosen to reflect the specific physiological changes that occur during menopause, including shifts in bone metabolism, immune function, and hormonal activity.

How Does Menopace Plus Work to Support Menopause?

The two-tablet system in Menopace Plus is intentional. Each component plays a distinct role:

Vitamin D and calcium-supporting nutrients help maintain normal bone density, which can decline after oestrogen levels fall.
Vitamin B6 contributes to the regulation of hormonal activity and supports normal psychological function — relevant given the mood fluctuations many women experience.
Vitamin E is an antioxidant that supports cell protection from oxidative stress.
Soy isoflavones are phytoestrogens — plant-derived compounds with a weak oestrogen-like effect. They are thought to interact with oestrogen receptors in the body, potentially helping to ease some menopausal symptoms.
Magnesium contributes to normal muscle function and the reduction of tiredness and fatigue.

It's worth noting that Menopace Plus is a food supplement, not a medicine. It is not a replacement for hormone replacement therapy (HRT) and does not treat menopause clinically. If your symptoms are significantly affecting your quality of life, speak to your GP about all available options, including HRT.

Who Should Consider Using Menopace Plus Tablets?

Menopace Plus is formulated for adult women who are going through perimenopause or menopause and want nutritional support during this time. It may be particularly useful if you:

Are experiencing mild to moderate menopausal symptoms such as fatigue, mood changes, or hot flushes
Are concerned about bone health following the natural decline in oestrogen
Have dietary gaps that may be affecting your energy or immune function
Prefer a non-hormonal supplement approach alongside lifestyle changes

It is not suitable for women who are pregnant or breastfeeding, or for those with oestrogen-sensitive conditions such as certain hormone-dependent cancers. Always check with your GP or pharmacist if you are unsure whether this supplement is right for you.

How Does Menopace Plus Compare to Other Menopause Supplements?

Feature	Menopace Plus 56 Tablets	Standard Menopace Original
Isoflavone tablet included	Yes — separate daily tablet	No
Vitamin and mineral blend	Yes — broad spectrum	Yes — broad spectrum
Tablets per pack	56 (28-day supply)	30 or 90 tablets
Suitable for vegetarians	Yes	Yes

How Should You Store Menopace Plus and Is It Clinically Suitable for You?

Store Menopace Plus tablets below 25°C in a dry place, away from direct sunlight and out of the reach of children. Do not use after the expiry date printed on the pack. If you are taking any prescription medicines — particularly anticoagulants like warfarin — speak to your pharmacist before starting, as the vitamin E content may have an interaction. Women with a history of oestrogen-sensitive conditions should seek medical advice before using any isoflavone-containing supplement. Menopace Plus tablets are also available through our women's health collection alongside other products tailored to female wellbeing.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Menopace Plus 56 Tablets specifications

Treatment category	Menopause nutritional support
Mechanism of action	Provides vitamins, minerals, and soy isoflavones to support hormonal balance and general wellbeing during menopause
Effective for	Nutritional support during perimenopause and menopause
Suitable for	Adult women during perimenopause or menopause
Active ingredients	Vitamins B6, B12, C, D, E; folic acid; magnesium; zinc; soy isoflavones
Pack size	56 tablets (28-day supply)
UK classification	Food supplement
Preparation	Tablet
Route of administration	Oral

Specifications of Menopace Plus 56 Tablets

What Is Menopace Plus and What Is It Used For?

Menopace Plus 56 Tablets is a food supplement produced by Vitabiotics, one of the UK's most established supplement manufacturers. It is specifically formulated for women going through perimenopause or menopause. The product comes as a dual-tablet system: one Menopace vitamin and mineral tablet, and one isoflavone tablet, both taken once daily. Together, they are designed to help address the nutritional demands that change as oestrogen levels decline. This is not a hormonal treatment — it is a supplement intended to complement a balanced diet and healthy lifestyle during the menopause transition.

The NHS notes that menopause typically occurs between the ages of 45 and 55 in the UK, and that symptoms can include hot flushes, night sweats, mood changes, and fatigue. Nutritional support during this period can play a role in overall wellbeing, particularly where dietary intake may be insufficient.

What Do You Need to Know Before Using Menopace Plus?

Before starting Menopace Plus, it's important to consider whether it is appropriate for your individual circumstances. Please read the following carefully.

Do not take Menopace Plus if you:

Are pregnant or breastfeeding
Have or have had an oestrogen-sensitive condition, such as certain types of breast cancer, endometriosis, or uterine fibroids
Are allergic to soya or any other listed ingredient
Have a thyroid condition — soy isoflavones may affect thyroid function in some individuals

Potential drug interactions to be aware of:

Warfarin and other anticoagulants — vitamin E may enhance anticoagulant effects
Tamoxifen or other hormone-sensitive cancer treatments — isoflavones may interfere
Thyroid medications — soy may reduce absorption; take at least four hours apart
Iron supplements — vitamin C in this product may increase iron absorption; discuss with your pharmacist if you take prescribed iron

If you are unsure about any interactions, speak to your pharmacist before use. You can also browse our women's health range for additional support products.

How Should You Use Menopace Plus Correctly?

Take one tablet from each blister strip every day — one Menopace vitamin/mineral tablet and one isoflavone tablet.
Swallow both tablets whole with a full glass of water.
Take with your main meal to improve tolerability and absorption.
Do not exceed the recommended daily intake.
Continue daily for consistent nutritional support — benefits from isoflavones may take several weeks to become noticeable.

Indication	Age Group	Dose	Frequency
Menopause nutritional support	Adult women (typically 45+)	1 Menopace tablet + 1 isoflavone tablet	Once daily with main meal
Not applicable	Under 18 / pregnant / breastfeeding	Not recommended	—

What Are the Possible Side Effects of Menopace Plus?

Menopace Plus is generally well tolerated. Side effects are uncommon, but as with any supplement, some women may notice mild reactions, particularly when first starting. Taking the tablets with food significantly reduces the likelihood of gastrointestinal discomfort.

Common side effects:

Mild nausea, especially if taken on an empty stomach
Mild stomach discomfort or bloating
Urine may appear a brighter yellow — this is harmless and caused by riboflavin (vitamin B2)

Less common side effects:

Headache
Skin flushing (rarely associated with niacin content)
Allergic reactions — seek immediate medical attention if you notice swelling, rash, or difficulty breathing

If you experience any persistent or unusual symptoms, stop taking the supplement and consult your GP or pharmacist. For women who also experience sleep disturbances during menopause, our sleep aid collection may offer additional support options worth discussing with a healthcare professional.

How Should You Store Menopace Plus Safely?

Store below 25°C in a cool, dry place away from direct sunlight
Keep out of the reach and sight of children
Do not store in the bathroom or near a heat source
Do not use after the expiry date printed on the packaging
Do not transfer tablets to another container — keep in original blister packaging

References

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Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Menopace Plus tablets online in the UK?

You can buy Menopace Plus 56 Tablets directly from Cured Pharmacy, a GPhC-registered UK online pharmacy. Simply add the product to your basket and select your preferred delivery option at checkout. It is also available in some high street pharmacies and supermarkets across the UK.

How do Menopace Plus tablets work in the body?

Menopace Plus tablets work through a dual-action approach. The vitamin and mineral tablet addresses nutritional gaps common during menopause — such as vitamin D for bone health and vitamin B6 for hormonal regulation — while the isoflavone tablet provides phytoestrogens that may interact with oestrogen receptors to help ease some menopausal symptoms. The two tablets are designed to complement each other when taken together daily.

How do I take Menopace Plus step by step?

Take one tablet from each blister strip every day — that's one Menopace vitamin/mineral tablet and one isoflavone tablet. Swallow both whole with a full glass of water, ideally with your main meal. Do not chew or crush the tablets.

What is the best time of day to take Menopace Plus?

The manufacturer recommends taking both tablets with your main meal, which is typically lunch or dinner for most women. Taking them with food helps improve tolerability and may reduce the chance of mild stomach discomfort. Consistency matters — try to take them at the same time each day.

What are the side effects of Menopace Plus tablets?

Side effects are uncommon but can include mild nausea, stomach bloating, or a brighter yellow colour to urine — the latter is harmless and caused by riboflavin (vitamin B2). Rarely, some women may experience headache or skin flushing. If you notice any allergic reaction such as swelling or difficulty breathing, stop taking the supplement and seek medical attention immediately.

Who is Menopace Plus suitable for?

Menopace Plus is designed for adult women who are going through perimenopause or menopause and want nutritional support during this time. It is suitable for vegetarians. It is not recommended for women who are pregnant, breastfeeding, or who have oestrogen-sensitive conditions such as certain hormone-dependent cancers.

Can I take Menopace Plus if I am on HRT?

Many women take Menopace Plus alongside HRT, but you should always check with your GP or pharmacist first. The isoflavone component has a weak phytoestrogenic effect, and your doctor will want to ensure there are no interactions with your specific HRT formulation. Never adjust your HRT without medical guidance.

What happens if I miss a dose of Menopace Plus?

If you forget to take your daily tablets, simply take them as soon as you remember on the same day. If you don't remember until the following day, skip the missed dose entirely and continue with your normal schedule. Do not take a double dose to make up for a missed one.

How long does it take for Menopace Plus to work?

Nutritional supplements generally take time to build up in the body. Some women notice improvements in energy and general wellbeing within a few weeks, while the effects of isoflavones on menopausal symptoms may take up to 8–12 weeks of consistent daily use. Results vary between individuals, and Menopace Plus is not a substitute for medical treatment if your symptoms are severe.

How long can I take Menopace Plus for?

Menopace Plus can be taken throughout the menopause transition, which may last several years. There is no set maximum duration for a food supplement of this type, but it is good practice to review your supplement use periodically with your GP or pharmacist. If your symptoms change significantly, seek medical advice rather than relying solely on supplementation. You can find further support through our vitamins and supplements collection.

Does Menopace Plus contain soy or allergens?

Yes — the isoflavone tablet in Menopace Plus contains soy isoflavones derived from soya. If you have a soya allergy, you should not take this product. Always check the full ingredient list on the packaging before use, and speak to your pharmacist if you have any known food allergies or intolerances.

Can Menopace Plus help with hot flushes?

The soy isoflavones in Menopace Plus are phytoestrogens that some research suggests may help reduce the frequency or severity of hot flushes in some women. However, the evidence is mixed, and results vary considerably between individuals. Menopace Plus is a food supplement, not a licensed medicine for hot flushes — speak to your GP if hot flushes are significantly affecting your quality of life.

What are the alternatives to Menopace Plus for menopause support?

Alternatives include other menopause-specific supplements such as Menopace Original (without the separate isoflavone tablet), black cohosh supplements, or evening primrose oil. For women with more significant symptoms, HRT prescribed by a GP remains the most clinically supported option. Browse our women's health collection for a wider range of support products.

Is Menopace Plus suitable for vegetarians or vegans?

Menopace Plus is suitable for vegetarians. However, it is not certified vegan — the product may contain ingredients of animal origin such as gelatine in the tablet coating. Check the current product label for the most up-to-date ingredient information, as formulations can change.

What are the latest studies on isoflavones and menopause?

Research into soy isoflavones and menopause symptoms is ongoing. Some studies suggest a modest benefit in reducing hot flush frequency, particularly in women who are efficient metabolisers of isoflavones. The NHS notes that complementary therapies including phytoestrogens may help some women, but the evidence is not conclusive. Always discuss supplement choices with your GP, especially if you have a history of hormone-sensitive conditions.

How Should You Use Menopace Plus?

Menopace Plus comes as a dual-tablet system, and using it correctly is straightforward. Each blister strip contains two different tablets — a Menopace vitamin and mineral tablet, and a separate isoflavone tablet — and both should be taken every day for consistent nutritional support.

What Is the Correct Dose of Menopace Plus?

The recommended dose is one of each tablet per day — no more. This product is a food supplement, and exceeding the stated dose does not increase benefit and may cause unwanted effects. The table below summarises the dosage guidance.

When Is the Best Time to Use Menopace Plus?

Take both tablets with your main meal — whether that's lunch or dinner. Food helps the body absorb fat-soluble vitamins such as vitamin D and vitamin E more effectively, and it also reduces the likelihood of any mild nausea. Picking a consistent time each day, such as with your evening meal, makes it easier to remember and helps you build a reliable habit.

If you are also taking thyroid medication, leave at least four hours between your thyroid medicine and Menopace Plus, as soy isoflavones may affect absorption of certain thyroid drugs.

How Long Can You Use Menopace Plus For?

Menopace Plus can be used throughout the menopause transition, which for many women spans several years. There is no fixed maximum duration for this type of food supplement. However, it is sensible to review your supplement use with your GP or pharmacist at least once a year, particularly if your symptoms or health circumstances change.

If you find your symptoms are worsening or not improving despite consistent use, speak to your GP about additional options, including HRT. Supplements work best as part of a broader approach that includes a balanced diet, regular physical activity, and appropriate medical care.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Menopace Plus?

Menopace Plus is generally well tolerated by most women when taken as directed. The most frequently reported side effects are mild and gastrointestinal in nature, and they are most likely to occur if the tablets are taken on an empty stomach rather than with food.

Mild nausea or queasiness, particularly when first starting
Stomach bloating or mild abdominal discomfort
Bright yellow or orange-tinted urine — this is harmless and caused by riboflavin (vitamin B2) being excreted by the kidneys

Taking both tablets with your main meal significantly reduces the likelihood of these effects. Most women find that any initial stomach sensitivity settles within the first week or two of use.

What Are the Less Common Side Effects of Menopace Plus?

Less commonly, some women may notice the following. These are not typical but are worth being aware of before you start.

Headache
Mild skin flushing — occasionally associated with niacin (vitamin B3) content at higher intakes
Changes in bowel habits, such as mild constipation or loose stools
Breast tenderness — rarely reported with isoflavone-containing supplements

If any of these effects persist beyond a couple of weeks or feel particularly uncomfortable, it is worth speaking to your pharmacist before continuing.

What Are the Serious Side Effects of Menopace Plus?

Serious side effects are rare with food supplements of this type, but they can occur. Stop taking Menopace Plus immediately and seek urgent medical attention if you experience any of the following:

Signs of an allergic reaction — including skin rash, itching, swelling of the face, lips, or throat, or difficulty breathing
Severe abdominal pain
Unexplained bruising or bleeding — particularly relevant if you are also taking anticoagulant medicines such as warfarin, as vitamin E may enhance their effect

These reactions are uncommon, but they require prompt attention. Do not wait to see if symptoms resolve on their own.

What Should You Do If You Experience Side Effects?

For mild side effects such as nausea or bloating, try taking the tablets with a larger meal or switching to a different time of day. If symptoms persist, stop taking the supplement and speak to your pharmacist. You do not need to visit A&E for mild gastrointestinal symptoms, but your pharmacist can advise on whether to continue or switch to an alternative product.

For any serious or allergic reaction, call 999 or go to your nearest A&E immediately. You can also report suspected side effects from food supplements to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Menopace Plus Interact With Other Medicines?

Yes — certain interactions are worth knowing about before you start. The vitamin E content may enhance the effects of anticoagulant medicines such as warfarin, potentially increasing bleeding risk. The soy isoflavones may interfere with tamoxifen or other hormone-sensitive cancer treatments. If you take thyroid medication, leave at least four hours between your thyroid medicine and Menopace Plus, as soy can reduce drug absorption. Vitamin C in the formulation may also increase iron absorption, which could be relevant if you take prescribed iron supplements.

Always tell your GP or pharmacist about all supplements you are taking, not just prescription medicines. Interactions can be subtle but clinically significant.

If you are concerned about any side effects, contact your pharmacist or GP immediately.