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Hycosan Plus Eye Drops

Hycosan Plus Eye Drops

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  • ✔️ Preservative-free formula suitable for sensitive eyes
  • ✔️ 0.1% sodium hyaluronate stabilises and restores the tear film
  • ✔️ COMOD system delivers one precise sterile drop every time
  • ✔️ Relieves dry, gritty, and irritated eyes throughout the day
  • ✔️ Compatible with contact lens wear when lenses removed first

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What Are Hycosan Plus Eye Drops?

 

Hycosan Plus eye drops are a preservative-free lubricating eye drop designed to relieve the discomfort of dry, irritated, or tired eyes. Each bottle contains a 0.1% sodium hyaluronate solution — a substance that closely resembles the eye's natural tear film — delivered through the patented COMOD multi-dose system. Dry eye is a surprisingly common condition in the UK, affecting millions of people, and can be triggered by screen use, air conditioning, contact lens wear, certain medications, or simply getting older. If your eyes feel gritty, sore, or like something is stuck in them, you are not alone.

At just £9.99, Hycosan Plus offers an accessible, clinician-recommended option for everyday dry eye management. You can browse the full range of eye care products at Cured Pharmacy to find the right solution for your needs.

 

How Do Hycosan Plus Eye Drops Work?

 

The active ingredient, sodium hyaluronate, is a naturally occurring polysaccharide found in the body's own connective tissues and fluids. When applied to the eye, it forms a stable, viscoelastic layer over the ocular surface. This layer does several things at once:

  • Retains moisture on the corneal surface, reducing evaporation of the tear film
  • Reduces friction between the eyelid and the eye during blinking
  • Supports the healing of minor surface irritation
  • Provides a smooth, clear optical surface for comfortable vision

The COMOD (Continuous Mono-Dose) delivery system is worth mentioning here. It dispenses a precise, single drop each time without introducing air into the bottle, which means no preservatives are needed to keep the solution sterile. This is particularly important for people with sensitive eyes or those who use drops frequently throughout the day.

 

Who Should Use Hycosan Plus Eye Drops?

 

These drops are suitable for a wide range of people experiencing dry or uncomfortable eyes. They are particularly well suited to those who need to use lubricating drops regularly, since the preservative-free formula reduces the risk of irritation associated with long-term use of preserved drops.

  • Adults and older children experiencing dry, gritty, or irritated eyes
  • Contact lens wearers (remove lenses before use; reinsert after 15 minutes)
  • People who spend long hours in front of screens
  • Those in air-conditioned or centrally heated environments
  • Individuals with mild to moderate dry eye disease

 

How Does Hycosan Plus Compare to Other Dry Eye Drops?

 

Feature Hycosan Plus Hycosan Extra Standard Preserved Drops
Sodium hyaluronate concentration 0.1% 0.2% Varies
Preservative free Yes Yes No
COMOD delivery system Yes Yes No
Suitable for contact lens wearers Yes (remove first) Yes (remove first) Check label
Shelf life after opening 6 months 6 months Typically 28 days

 

Is Hycosan Plus Suitable for Long-Term Use?

 

Because Hycosan Plus eye drops are preservative free, they are generally considered suitable for long-term, frequent use. Preservatives found in some other eye drops — such as benzalkonium chloride — can cause cumulative irritation to the ocular surface when used multiple times daily over extended periods. The COMOD system eliminates this concern entirely. If you have been diagnosed with chronic dry eye disease, or if your symptoms persist despite regular use of lubricating drops, it is worth speaking to your GP or an optometrist for a full assessment.

If you are managing other health conditions alongside dry eye — for example, if you take antihistamines for allergy or hay fever, which can worsen dry eye symptoms — it is worth discussing your full medication list with a pharmacist before starting any new eye drop.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Hycosan Plus Eye Drops specifications
Treatment category Dry eye / Ocular lubricant
Active ingredient Sodium hyaluronate 0.1%
Mechanism of action Forms a viscoelastic lubricating layer over the ocular surface to retain moisture and reduce friction
Suitable for Adults and children; contact lens wearers (remove before use)
Pack size 7.5 ml
UK classification CE-marked medical device
Preparation Sterile aqueous eye drops solution
Route of administration Ophthalmic (topical)
Preservative free Yes — COMOD multi-dose system

Specifications of Hycosan Plus Eye Drops

 

What Are Hycosan Plus Eye Drops and What Are They Used For?

 

Hycosan Plus Eye Drops are a sterile, preservative-free ocular lubricant used to relieve the symptoms of dry eye syndrome. Dry eye occurs when the eyes do not produce enough tears, or when the tears evaporate too quickly, leaving the surface of the eye inadequately lubricated. Symptoms can include a gritty or burning sensation, redness, sensitivity to light, and intermittent blurred vision. The NHS notes that dry eye is a very common condition, particularly in older adults and those who spend extended time using digital screens.

The drops are classified as a CE-marked medical device rather than a licensed medicine, which means they do not require a prescription and are available over the counter. They are intended for symptomatic relief and are not a treatment for any underlying disease causing dry eye.

 

What Do You Need to Know Before Using Hycosan Plus Eye Drops?

 

Before using these drops, read the following carefully. While Hycosan Plus is generally well tolerated, there are some situations where caution is needed.

Do not use Hycosan Plus if:

  • You are allergic to sodium hyaluronate or any other ingredient in the formulation
  • You have an active eye infection — treat the infection first and seek medical advice
  • You are wearing contact lenses at the time of application

Take care and speak to a pharmacist or GP if:

  • You have had recent eye surgery
  • You are using any other eye drops or eye ointments at the same time
  • Your dry eye symptoms are severe, worsening, or accompanied by pain or vision changes
  • You are pregnant or breastfeeding (though topical ocular use is generally considered low risk, always check with your healthcare provider)

Known interactions:

  • No significant drug interactions have been identified for topical sodium hyaluronate
  • If using other eye drops, wait at least 5 minutes between applications to avoid diluting either product
  • Apply Hycosan Plus last if also using eye ointments, as ointments can reduce absorption of drops

 

How Should You Use Hycosan Plus Eye Drops?

 

Using the COMOD bottle correctly ensures you get a consistent, single drop each time. Follow these steps carefully:

  1. Wash your hands thoroughly before handling the bottle
  2. Remove contact lenses if you wear them
  3. Hold the bottle pointing downwards and press the valve once to prime it if using for the first time
  4. Tilt your head back slightly and gently pull down your lower eyelid to create a small pocket
  5. Hold the bottle tip close to your eye without touching it, and press once to release one drop
  6. Close your eye gently and blink a few times to spread the drop evenly
  7. Repeat in the other eye if needed
  8. Wait at least 15 minutes before reinserting contact lenses
Indication Age Group Dose Frequency
Dry, irritated eyes Adults and children 1 drop per affected eye Up to 4 times daily, or as needed
Contact lens-related dryness Adults 1 drop per eye Before and/or after lens wear (remove lenses first)

 

What Are the Possible Side Effects of Hycosan Plus Eye Drops?

 

Side effects with Hycosan Plus are uncommon. Because the formula is preservative free, it is less likely to cause the cumulative irritation sometimes seen with preserved eye drops used over long periods. That said, as with any topical ocular product, some people may notice mild effects.

Common side effects:

  • Temporary blurred vision immediately after instillation (clears within a few minutes)
  • Mild, transient stinging or burning sensation on application

Less common side effects:

  • Eye redness or irritation that persists beyond a few minutes
  • Watery eyes or increased tearing shortly after use
  • Eyelid swelling or discomfort (may indicate sensitivity — discontinue and seek advice)

If you experience any worsening of symptoms, significant pain, sudden vision changes, or signs of an allergic reaction such as swelling around the eye, stop using the drops and contact your GP or optometrist promptly. You can also find general guidance on eye health through the NHS. If you are managing multiple health concerns, our eye care collection includes a range of products to support ocular comfort.

 

How Should You Store Hycosan Plus Eye Drops?

 

Correct storage keeps the drops sterile and effective for the full duration of use. Follow these guidelines:

  • Store below 25°C — do not refrigerate unless specifically advised
  • Keep the bottle tightly closed when not in use
  • Do not use after the expiry date printed on the bottle or carton
  • Discard the bottle 6 months after first opening, even if product remains
  • Keep out of reach and sight of children
  • Do not share the bottle with other people — this reduces the risk of cross-contamination
  • Store away from direct sunlight and heat sources

If you are also managing other health conditions that require regular medication — for example, if you use vitamins and supplements to support general wellbeing — always store each product according to its individual instructions.

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Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Hycosan Plus eye drops online in the UK?

You can buy Hycosan Plus eye drops directly from Cured Pharmacy for £9.99, with no prescription required. They are dispatched quickly and discreetly to your door. Browse our full eye care collection for additional dry eye and ocular comfort products.

How do Hycosan Plus eye drops work in the eye?

Hycosan Plus contains 0.1% sodium hyaluronate, which forms a stable, moisture-retaining layer over the surface of the eye. This layer reduces friction during blinking, stabilises the tear film, and helps relieve the gritty, burning sensation associated with dry eye. The effect is noticeable quickly, though individual results vary depending on the severity of dryness.

Are Hycosan Plus eye drops preservative free?

Yes, Hycosan Plus eye drops are completely preservative free. The COMOD multi-dose delivery system keeps the solution sterile without the need for chemical preservatives such as benzalkonium chloride. This makes them a good choice for people with sensitive eyes or those who need to use lubricating drops multiple times a day.

How do I use Hycosan Plus eye drops step by step?

Remove any contact lenses first, then tilt your head back and gently pull down your lower eyelid. Press the COMOD bottle once to release a single drop into the eye, then blink gently to distribute it. Wait at least 15 minutes before reinserting contact lenses, and wash your hands before and after use.

Can I use Hycosan Plus eye drops with contact lenses?

You must remove your contact lenses before applying Hycosan Plus eye drops. Once the drops have been applied, wait a minimum of 15 minutes before putting your lenses back in. This waiting period allows the solution to be properly absorbed and prevents the lenses from interfering with the drop's effectiveness.

What is the correct dose of Hycosan Plus eye drops?

The standard dose is one drop per affected eye, applied up to four times daily or as often as needed to relieve symptoms. There is no strict maximum frequency for preservative-free drops, but if you find you need them very frequently — more than six times a day — it is worth speaking to your GP or optometrist about your dry eye management.

What are the side effects of Hycosan Plus eye drops?

Side effects are uncommon but can include temporary blurred vision immediately after application and a mild stinging or burning sensation. These effects are usually brief and resolve within a few minutes. If you experience persistent redness, pain, or swelling around the eye, stop using the drops and seek medical advice.

How long can I use Hycosan Plus eye drops for?

Hycosan Plus is suitable for long-term use, including for people with chronic dry eye disease. The bottle should be discarded six months after first opening, regardless of how much product remains. If your symptoms have not improved after several weeks of regular use, consult your GP or optometrist for further assessment.

What is the difference between Hycosan Plus and Hycosan Extra?

The key difference is the concentration of sodium hyaluronate: Hycosan Plus contains 0.1%, while Hycosan Extra contains 0.2%. Hycosan Extra is generally recommended for more severe or persistent dry eye symptoms, whereas Hycosan Plus is well suited to mild to moderate dryness and everyday use. Both are preservative free and use the COMOD delivery system.

What are the ingredients in Hycosan Plus eye drops?

The active ingredient is sodium hyaluronate 0.1%. The excipients include sodium citrate, citric acid monohydrate, sorbitol, and water for injections. The formula contains no preservatives, making it suitable for sensitive eyes and frequent use throughout the day.

Can I use Hycosan Plus eye drops if I have had eye surgery?

If you have recently had eye surgery — such as cataract surgery or laser eye treatment — you should consult your surgeon or ophthalmologist before using any new eye drops, including Hycosan Plus. Dry eye is common after eye surgery, and your clinical team will advise on the most appropriate lubricant for your recovery.

Can Hycosan Plus eye drops be used during pregnancy?

Topical ocular use of sodium hyaluronate is generally considered low risk during pregnancy, as systemic absorption is minimal. However, as with any product used during pregnancy or breastfeeding, it is always best to check with your GP or midwife before starting use. They can confirm whether Hycosan Plus is appropriate for your individual circumstances.

What happens if I accidentally use too many drops of Hycosan Plus?

Using more drops than recommended is unlikely to cause serious harm, as the solution is non-toxic and will largely drain away through the tear ducts. You may experience temporary blurred vision or a watery sensation. If you have concerns after accidental overuse, contact your pharmacist or NHS 111 for guidance.

Are there alternatives to Hycosan Plus for dry eyes?

Yes, there are several alternatives depending on the severity of your symptoms. Options include Hycosan Extra (0.2% sodium hyaluronate for more severe dryness), Hylo-Forte, Systane Ultra, and Optive. If you are also managing conditions like allergies or hay fever that worsen dry eye, your pharmacist can help you choose the most suitable product. Always consider preservative-free options if you use drops frequently.

What does the latest research say about sodium hyaluronate eye drops?

Clinical studies consistently support the use of sodium hyaluronate as an effective ocular lubricant for dry eye disease. Research published in peer-reviewed ophthalmology journals has shown that sodium hyaluronate improves tear film stability, reduces ocular surface damage scores, and provides meaningful symptom relief. The NHS recommends lubricating eye drops as a first-line treatment for dry eye, and sodium hyaluronate-based products are among the most widely used formulations in clinical practice.

How Should You Use Hycosan Plus Eye Drops?

Using Hycosan Plus correctly ensures you get the full benefit of each drop and keep the bottle sterile throughout its six-month lifespan. The COMOD delivery system is designed to dispense exactly one drop per press — do not squeeze the bottle or press multiple times in quick succession.

What Is the Correct Dose of Hycosan Plus Eye Drops?

The recommended dose is one drop per affected eye, applied as often as needed to relieve symptoms. For most people, this means two to four times daily, though the preservative-free formula means more frequent use is generally well tolerated if your symptoms require it.

When Is the Best Time to Use Hycosan Plus Eye Drops?

There is no single fixed time that suits everyone — the best approach is to use the drops whenever your eyes feel dry, uncomfortable, or strained. Many people find it helpful to apply a drop first thing in the morning, when eyes can feel particularly dry after sleep, and again in the evening after a day of screen use or time in air-conditioned environments. If you wear contact lenses, applying a drop before insertion and after removal can help maintain comfort throughout the day.

How Long Can You Use Hycosan Plus Eye Drops For?

Hycosan Plus is suitable for ongoing, long-term use in people with chronic dry eye. Because the formula is preservative free, there is no cumulative risk of preservative-related ocular surface damage with extended use. Once opened, the bottle remains usable for up to six months — write the opening date on the label so you can track this easily. If your symptoms persist or worsen despite regular use, or if you develop new symptoms such as pain or significant vision changes, consult your GP or optometrist for a full review.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Hycosan Plus Eye Drops?

Hycosan Plus is generally very well tolerated, particularly because it is preservative free. The most frequently reported effects are mild and transient, resolving within a few minutes of application without any treatment needed.

  • Temporary blurred vision immediately after instilling the drop
  • Mild stinging or burning sensation on first contact with the eye
  • A brief watery or wet sensation as the drop spreads across the ocular surface

These effects are a normal response to introducing any liquid into the eye and are not a sign that the product is unsuitable for you. Blinking a few times after application usually resolves them quickly.

What Are the Less Common Side Effects of Hycosan Plus Eye Drops?

Less commonly, some people may notice effects that persist slightly longer or feel more noticeable. If any of the following occur and do not settle within a short time, stop using the drops and seek advice from a pharmacist or GP.

  • Persistent redness or irritation of the eye or surrounding skin
  • Increased sensitivity to light (photophobia)
  • A feeling of something in the eye that does not resolve after blinking
  • Eyelid swelling or puffiness
  • Increased tearing or discharge

What Are the Serious Side Effects of Hycosan Plus Eye Drops?

Serious side effects are rare with topical sodium hyaluronate. However, you should stop using the drops immediately and seek urgent medical attention if you experience any of the following:

  • Sudden or significant change in vision
  • Severe eye pain that does not resolve
  • Signs of an allergic reaction, such as marked swelling of the eyelids, face, or lips, or difficulty breathing
  • Eye infection symptoms — increased discharge, crusting, or worsening redness with pain

Allergic reactions to sodium hyaluronate are uncommon but possible. If you have a known hypersensitivity to any ingredient in the formulation, do not use this product.

What Should You Do If You Experience Side Effects of Hycosan Plus?

For mild, transient effects such as brief stinging or blurred vision, no action is usually needed beyond waiting a few minutes. If side effects are persistent, worsening, or causing you concern, stop using the drops and contact your pharmacist or GP. You can also report suspected side effects of medical devices to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Do not ignore new or worsening eye symptoms — early assessment by an optometrist or GP can prevent complications.

Can Hycosan Plus Eye Drops Interact With Other Medicines?

No significant drug interactions have been identified for topical sodium hyaluronate. However, if you are using other eye drops or eye ointments at the same time, there are some practical points to bear in mind. Always leave at least five minutes between applying different eye drops to prevent one product diluting or washing out the other. If you are also using an eye ointment, apply Hycosan Plus first and wait several minutes before applying the ointment, as ointments can form a barrier that reduces absorption of drops applied afterwards. Always inform your pharmacist of all eye preparations you are currently using.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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