Canesten Thrush Combi - 500mg Vaginal Pessary and 2% External Cream

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Canesten Thrush Combi Treatment for Complete Relief

You receive both internal and external treatment with this dual-action pack containing a 500mg clotrimazole vaginal pessary and 2% clotrimazole external cream. This combination addresses thrush symptoms both inside and outside the vaginal area for comprehensive relief.

The canesten thrush combi provides targeted treatment where you need it most. The pessary treats the internal infection whilst the cream soothes external irritation and itching around the vulval area.

How Clotrimazole Eliminates Thrush Infections

Clotrimazole belongs to a group of medicines called antifungals. It works by damaging the cell walls of the Candida fungus that causes thrush, preventing it from growing and spreading.

The pessary releases clotrimazole directly into the vagina where it can reach high concentrations to fight the infection. The cream provides additional antifungal action on external areas whilst also moisturising irritated skin. You can explore our full range of thrush treatments for other options.

Who Should Use This Thrush Treatment

This treatment suits women aged 16-60 years experiencing their first episode of thrush or those with recurring symptoms who have previously been diagnosed by a doctor. You should recognise typical thrush symptoms before using this medicine.

Thick, white vaginal discharge that doesn't smell
Itching and irritation around the vagina and vulva
Soreness and stinging during urination or intercourse
Redness and swelling of the vulval area

Why Choose the Combination Pack

The dual approach treats both internal and external symptoms simultaneously, which may provide faster relief than using either treatment alone. Many women find external symptoms persist even after internal treatment, making the cream component particularly valuable.

The single-dose pessary offers convenience whilst the cream can be applied as needed for symptom relief. This eliminates the need to purchase separate products or make multiple treatment decisions.

Clinical Suitability and Storage Requirements

Store both components below 25°C in a dry place away from direct sunlight. Do not use if you're pregnant, breastfeeding, or under 16 years old without medical advice. The pessary may damage latex condoms and diaphragms, so use alternative contraception during treatment.

Consult your doctor before use if you have more than two thrush infections in six months, abnormal vaginal bleeding, or if symptoms don't improve within three days of treatment.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

How to Use the Vaginal Pessary

Insert the 500mg pessary high into your vagina using the applicator provided, preferably at bedtime. Remove the pessary from its packaging and place it in the applicator. Lie on your back with your knees bent and gently insert the applicator as far as comfortable into your vagina. Press the plunger to release the pessary, then remove the applicator.

Use the pessary as a single dose. The treatment works over several days as the pessary dissolves and releases the active ingredient. You may notice some discharge as the pessary dissolves, which is normal.

Applying the External Cream

Apply a thin layer of the 2% clotrimazole cream to the affected external areas two to three times daily. Wash your hands before and after application. Gently massage the cream into the skin around the vulva and any other affected areas.

Continue using the cream until symptoms disappear, which typically takes two to three days after using the pessary. Do not use the cream for more than seven days unless advised by your doctor.

Possible Side Effects of Clotrimazole Treatment

Like all medicines, Canesten Thrush Combi can have side effects, although not everyone will experience them. Most side effects are mild and temporary, affecting the area where you apply the treatment. If you experience persistent symptoms, you may benefit from other women's health treatments available.

The most common side effects include local irritation, burning sensation, or increased itching when you first apply the cream or insert the pessary. These effects usually settle as your body adjusts to the treatment.

Burning or stinging sensation
Skin irritation or redness
Itching at the application site
Vaginal burning or irritation
Pelvic cramping or pain
Unusual vaginal discharge
Swelling of the vulval area
Allergic skin reactions
Contact dermatitis
Blistering of treated skin

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.