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Allergy & Hayfever Chlorphenamine - 28 Tablets

Allergy & Hayfever Chlorphenamine - 28 Tablets

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  • ✔️ Relieves hay fever, hives, and allergic rhinitis symptoms
  • ✔️ Contains chlorphenamine maleate 4mg per tablet
  • ✔️ Starts working within 30 minutes of taking a dose
  • ✔️ Suitable for adults and children aged 6 and over
  • ✔️ 28 tablets per pack — affordable allergy relief at £1.99

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What Are Chlorphenamine Tablets and How Do They Help Allergies?

 

If sneezing fits, itchy eyes, and a constantly runny nose are making your day miserable, you are not alone. Hay fever affects around 1 in 5 people in the UK, and allergic reactions can strike at any time of year. Chlorphenamine tablets are one of the most widely used over-the-counter antihistamines available, offering fast-acting relief from a range of allergy symptoms. At just £1.99 for 28 tablets, this is an affordable option that has been trusted by patients and pharmacists for decades. You can browse our full range of treatments in our allergy and hay fever collection.

Each tablet contains chlorphenamine maleate 4mg as the active ingredient. This is a first-generation antihistamine, meaning it works quickly and is well-established in clinical practice. It is licensed in the UK for the relief of hay fever, allergic rhinitis, urticaria (hives), insect bites and stings, food allergies, and other hypersensitivity reactions.

 

How Does Chlorphenamine Work to Relieve Allergy Symptoms?

 

When your body encounters an allergen — pollen, pet dander, dust mites — it releases a chemical called histamine. Histamine binds to receptors throughout the body and triggers the familiar cascade of symptoms: sneezing, itching, watery eyes, and nasal congestion. Chlorphenamine works by competitively blocking these H1 histamine receptors, stopping histamine from binding and preventing those symptoms from developing.

  • Absorbed from the gastrointestinal tract after oral administration
  • Reaches peak plasma concentration within 2–3 hours
  • Crosses the blood-brain barrier, contributing to its sedative effect
  • Metabolised in the liver and excreted primarily via the kidneys

Because it is a first-generation antihistamine, it does have a sedating effect for many people. This is worth bearing in mind if you need to drive or concentrate at work.

 

Who Should Use Chlorphenamine Tablets?

 

These tablets are suitable for a broad range of patients dealing with allergic conditions. They are particularly useful during the hay fever season, but they can also help manage symptoms triggered by animals, dust, or certain foods. That said, they are not appropriate for everyone.

  • Adults and children aged 6 years and over
  • People experiencing hay fever or seasonal allergic rhinitis
  • Those with urticaria (hives) or skin reactions from insect bites
  • Patients with mild food allergy symptoms (under medical guidance)

They are not recommended for children under 6, pregnant or breastfeeding women without medical advice, or people with certain conditions such as glaucoma, urinary retention, or epilepsy. Always check with your pharmacist if you are unsure.

 

How Do Chlorphenamine Tablets Compare to Non-Drowsy Antihistamines?

 

Feature Chlorphenamine 4mg (This Product) Loratadine 10mg (Non-Drowsy)
Generation First-generation Second-generation
Sedating effect Yes — commonly causes drowsiness Minimal — generally non-sedating
Dosing frequency Every 4–6 hours (up to 6 tablets/day) Once daily
Suitable for driving No — avoid driving after use Generally yes, with caution
Price (28 tablets) £1.99 Typically £2.50–£5.00

 

How Should You Store Chlorphenamine Tablets and Are They Right for You?

 

Store your chlorphenamine tablets below 25°C in a dry place, away from direct sunlight. Keep them out of reach and sight of children. Do not use them after the expiry date printed on the packaging. If you are managing multiple allergy symptoms — for example, itchy eyes alongside nasal congestion — you might also want to explore our eye care collection for complementary relief options.

It is worth thinking carefully about whether a sedating antihistamine suits your lifestyle. If you work shifts, drive regularly, or need to stay alert during the day, a non-drowsy alternative may be more practical. Speak to your pharmacist — they can help you choose the right option based on your symptoms and daily routine.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Allergy & Hayfever Chlorphenamine 28 Tablets specifications
Treatment category Allergy & Hay Fever
Mechanism of action H1 histamine receptor antagonist
Effective for Hay fever, allergic rhinitis, urticaria, insect bites, food allergy symptoms
Suitable for Adults and children aged 6 years and over
Active ingredient Chlorphenamine maleate 4mg
Pack size 28 tablets
Strength 4mg per tablet
UK classification General Sale List (GSL)
Drug class First-generation antihistamine
Preparation Tablet
Route of administration Oral

Specifications of Allergy & Hayfever Chlorphenamine 28 Tablets

 

What Is Chlorphenamine and What Is It Used For?

 

Chlorphenamine maleate 4mg tablets are an antihistamine medicine used to relieve the symptoms of allergic conditions. According to the NHS, antihistamines are the main medicines used for hay fever and work best when taken before symptoms begin. This product is suitable for adults and children aged 6 and over and is available without a prescription.

It is used to treat:

  • Hay fever and seasonal allergic rhinitis
  • Perennial (year-round) allergic rhinitis
  • Urticaria (hives) and skin rashes caused by allergies
  • Reactions to insect bites and stings
  • Mild food allergy symptoms
  • Allergic conjunctivitis (itchy, watery eyes)

 

What Do You Need to Know Before Using Chlorphenamine Tablets?

 

Do not take these tablets if any of the following apply to you:

  • You are allergic to chlorphenamine or any other ingredient in the tablet
  • You are under 6 years of age
  • You have acute asthma or a lower respiratory tract condition
  • You have angle-closure glaucoma
  • You have urinary retention or an enlarged prostate
  • You are taking monoamine oxidase inhibitors (MAOIs) or have taken them in the last 14 days
  • You are pregnant or breastfeeding — seek medical advice first
  • You have epilepsy or a history of seizures

The following medicines may interact with chlorphenamine:

  • MAOIs — risk of serious interaction; do not combine
  • Tricyclic antidepressants — increased sedative and anticholinergic effects
  • Other sedatives, sleeping tablets, or anxiolytics — additive drowsiness
  • Alcohol — significantly increases sedation; avoid completely
  • Anticholinergic medicines — increased risk of dry mouth, urinary retention, and constipation

 

How Should You Use Chlorphenamine Tablets?

 

Always take this medicine exactly as described in the patient information leaflet. If you are unsure, ask your pharmacist. Taking it with food or a glass of milk can help reduce the chance of stomach upset.

  1. Check the expiry date on the packaging before use
  2. Swallow the tablet whole with a glass of water
  3. Take with food if your stomach feels sensitive
  4. Do not crush or chew the tablet unless advised to do so
  5. Do not exceed the maximum daily dose for your age group
  6. Do not drive or operate machinery after taking this medicine
Age Group Dose Frequency Maximum Daily Dose
Adults & children 12+ 1 tablet (4mg) Every 4–6 hours 6 tablets (24mg)
Children 6–12 years ½ tablet (2mg) Every 4–6 hours 3 tablets (12mg)
Children under 6 Not recommended

 

What Are the Possible Side Effects of Chlorphenamine Tablets?

 

Like all medicines, chlorphenamine can cause side effects, although not everyone experiences them. The NHS notes that drowsiness is the most commonly reported effect with first-generation antihistamines. If you find the sedation problematic, speak to your pharmacist about whether a non-sedating alternative might suit you better. You can also explore our cold and flu collection if your symptoms overlap with a seasonal illness.

Common side effects:

  • Drowsiness and sedation
  • Dry mouth, nose, and throat
  • Blurred vision
  • Difficulty passing urine
  • Headache

Less common side effects:

  • Dizziness or impaired coordination
  • Nausea or stomach upset
  • Palpitations
  • Skin rashes or photosensitivity
  • Paradoxical excitability (particularly in children)

Stop taking the tablets and seek medical advice immediately if you experience difficulty breathing, severe skin reactions, or signs of an allergic reaction to the medicine itself.

 

How Should You Store Chlorphenamine Tablets?

 

  • Store below 25°C in a dry place
  • Keep away from direct sunlight and moisture
  • Keep out of the sight and reach of children
  • Do not use after the expiry date printed on the pack
  • Do not dispose of medicines via wastewater or household waste — return unused tablets to your pharmacy

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy chlorphenamine tablets online in the UK?

You can buy Allergy & Hayfever Chlorphenamine 28 Tablets directly from Cured Pharmacy for just £1.99, with fast dispatch from our GPhC-registered UK pharmacy. No prescription is needed as these are a General Sale List medicine. Browse our full allergy and hay fever collection for additional options.

How do chlorphenamine tablets work in the body?

Chlorphenamine is a first-generation antihistamine that blocks H1 histamine receptors, preventing histamine from triggering allergy symptoms such as sneezing, itching, and a runny nose. It is absorbed from the gut and reaches peak levels in the blood within 2–3 hours. Because it crosses the blood-brain barrier, it can cause drowsiness as a side effect.

What is the correct dose of chlorphenamine tablets for adults?

The standard adult dose is one 4mg tablet every four to six hours as needed, up to a maximum of six tablets (24mg) in any 24-hour period. Do not exceed this dose. If your symptoms are not controlled at the maximum dose, speak to your GP or pharmacist.

Can children take chlorphenamine tablets?

Chlorphenamine tablets are suitable for children aged 6 years and over, but the dose is lower than for adults. Children aged 6–12 should take half a tablet (2mg) every four to six hours, with a maximum of three tablets in 24 hours. These tablets are not suitable for children under 6 years of age.

Will chlorphenamine tablets make me drowsy?

Yes, drowsiness is a very common side effect of chlorphenamine because it is a sedating, first-generation antihistamine. You should avoid driving, cycling, or operating heavy machinery after taking it. Alcohol will significantly worsen the sedative effect, so avoid drinking while using this medicine.

What is the best time to take chlorphenamine tablets?

For hay fever, taking a tablet before you are exposed to your trigger — such as before going outdoors during high pollen counts — can help prevent symptoms from developing. Because chlorphenamine causes drowsiness, many people find it most convenient to take a dose in the evening. Always follow the dosing intervals and do not take more than the maximum daily dose.

What are the side effects of chlorphenamine tablets?

Common side effects include drowsiness, dry mouth, blurred vision, and difficulty urinating. Less common effects include headache, dizziness, nausea, and palpitations. In children, paradoxical excitability (becoming hyperactive rather than drowsy) can occasionally occur. Contact your pharmacist or GP if any side effect is severe or persistent.

How do I manage the drowsiness caused by chlorphenamine?

The most practical way to manage drowsiness is to take your dose in the evening or at a time when you do not need to drive or concentrate. Avoid alcohol entirely while taking this medicine. If daytime drowsiness is a significant problem for you, speak to your pharmacist about switching to a non-sedating second-generation antihistamine such as loratadine or cetirizine.

What happens if I miss a dose of chlorphenamine?

If you miss a dose, take it as soon as you remember — unless it is nearly time for your next scheduled dose, in which case skip the missed one entirely. Never take two doses at the same time to compensate for a missed dose. Chlorphenamine is taken as needed, so missing an occasional dose is unlikely to cause problems.

Who should not take chlorphenamine tablets?

These tablets are not suitable for children under 6, people taking MAOIs, those with angle-closure glaucoma, urinary retention, or acute asthma. Pregnant or breastfeeding women should seek medical advice before use. People with epilepsy or liver problems should also consult their GP or pharmacist first.

Can I take chlorphenamine tablets with other medicines?

Chlorphenamine can interact with several medicines, including MAOIs, tricyclic antidepressants, sedatives, sleeping tablets, and other antihistamines. Taking it alongside any of these can increase the risk of serious side effects. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are currently taking before starting chlorphenamine.

What are the alternatives to chlorphenamine tablets?

Non-sedating second-generation antihistamines such as loratadine (10mg once daily) and cetirizine (10mg once daily) are popular alternatives that are less likely to cause drowsiness. Nasal corticosteroid sprays are also recommended by the NHS for persistent hay fever symptoms. You can explore a wider range of options in our ear, nose and throat collection.

How long can you take chlorphenamine tablets for?

Chlorphenamine is intended for short-term use to manage acute allergy symptoms. During hay fever season, it can be used as needed throughout the season. If you find you need to take it continuously for more than a few weeks, or if your symptoms are not well controlled, speak to your GP about longer-term allergy management options.

Can I take chlorphenamine tablets during pregnancy?

Chlorphenamine is not recommended during pregnancy without medical advice, particularly during the first trimester. The NHS advises that pregnant women should speak to their GP or midwife before taking any antihistamine. Your doctor can advise on the safest option for managing allergy symptoms during pregnancy.

What is the latest guidance on using chlorphenamine for hay fever?

Current NHS guidance recommends antihistamines as a first-line treatment for mild to moderate hay fever symptoms. However, for more persistent or severe symptoms, nasal corticosteroid sprays are now considered more effective by clinical guidelines. Chlorphenamine remains a useful option for short-term or as-needed relief, particularly when sedation at night is acceptable or even beneficial.

How Should You Use Chlorphenamine Tablets?

Take chlorphenamine tablets exactly as directed in the patient information leaflet or as advised by your pharmacist. Swallowing the tablet whole with a full glass of water is the recommended method. Taking it with food or milk can help if you find it causes any stomach discomfort.

Follow these steps each time you take a dose:

What Is the Correct Dose of Chlorphenamine Tablets?

The dose depends on your age. Never exceed the maximum daily dose for your age group, and always leave at least four hours between doses. If you are giving this medicine to a child aged 6–12, you will need to break the tablet in half to achieve the correct 2mg dose.

When Is the Best Time to Use Chlorphenamine Tablets?

Because chlorphenamine commonly causes drowsiness, many people find it most practical to take their dose in the evening or before bed. This way, the sedative effect works in your favour rather than interfering with your day. If you need daytime relief — for example, during a high pollen day — take it when you do not need to drive or concentrate for several hours afterwards.

For hay fever, taking a tablet before you go outdoors or before anticipated allergen exposure can help prevent symptoms from developing in the first place, rather than waiting until they are already in full swing.

How Long Can You Use Chlorphenamine Tablets For?

Chlorphenamine is suitable for short-term use during periods of allergy symptoms, such as the hay fever season. Most people use it on an as-needed basis — taking a tablet when symptoms flare up and stopping when they settle. There is no fixed maximum duration for occasional use, but if you find yourself needing it every day for more than a few weeks, it is worth speaking to your GP.

Long-term daily use without medical review is not recommended. Your GP can assess whether a different treatment — such as a nasal corticosteroid spray or immunotherapy — might offer better long-term control of your allergy symptoms.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

What Are the Most Common Side Effects of Chlorphenamine Tablets?

Drowsiness is by far the most frequently reported side effect of chlorphenamine. Because it is a first-generation antihistamine, it crosses the blood-brain barrier and has a sedating effect on the central nervous system. This affects most people to some degree, which is why you must not drive or operate machinery after taking it.

  • Drowsiness and sedation
  • Dry mouth, nose, and throat
  • Blurred vision
  • Difficulty passing urine
  • Headache
  • Thickening of bronchial secretions

What Are the Less Common Side Effects of Chlorphenamine Tablets?

Some people experience side effects that are less frequent but still worth being aware of. These tend to be more likely at higher doses or in people who are more sensitive to anticholinergic medicines. If any of the following persist or become troublesome, contact your pharmacist.

  • Dizziness or impaired coordination
  • Nausea or stomach upset
  • Palpitations or rapid heartbeat
  • Skin rash or increased sensitivity to sunlight
  • Paradoxical excitability, restlessness, or irritability (more common in children)
  • Confusion or disorientation (more common in elderly patients)
  • Constipation

What Are the Serious Side Effects of Chlorphenamine Tablets?

Serious side effects are rare but require immediate medical attention. Stop taking chlorphenamine and seek urgent help if you experience any of the following. These may indicate a severe allergic reaction to the medicine itself or another serious adverse effect.

  • Difficulty breathing or swallowing
  • Severe skin reactions such as blistering or peeling
  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Seizures or convulsions
  • Severe urinary retention — inability to pass urine at all

What Should You Do If You Experience Side Effects?

For mild side effects such as a dry mouth or mild drowsiness, these often improve as your body adjusts. Staying well hydrated and taking the tablet in the evening can help manage these effects. If drowsiness is significantly affecting your daily life, speak to your pharmacist — a non-sedating antihistamine may be more appropriate for you.

If you experience any serious or unexpected side effects, stop taking the tablets and contact your GP or call NHS 111. In an emergency, call 999 or go to your nearest A&E department. You can also report side effects directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk.

Can Chlorphenamine Tablets Interact With Other Medicines?

Yes. Chlorphenamine has several clinically significant interactions that you need to be aware of before starting treatment. The most serious is with monoamine oxidase inhibitors (MAOIs) — combining these medicines can cause a dangerous reaction and is strictly contraindicated. You should not take chlorphenamine if you have used an MAOI in the last 14 days.

Other interactions to be aware of include tricyclic antidepressants, which increase both the sedative and anticholinergic effects of chlorphenamine. Taking it alongside other sedatives, sleeping tablets, or anxiolytics will also significantly increase drowsiness. Alcohol has the same effect and must be avoided entirely. Always tell your pharmacist about every medicine you are taking — including over-the-counter products and herbal remedies — before starting chlorphenamine.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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