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Actifed Dry Cough Syrup - 100ml

Actifed Dry Cough Syrup - 100ml

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  • ✔️ Relieves dry, tickly coughs with three active ingredients
  • ✔️ Reduces nasal congestion fast with pseudoephedrine decongestant
  • ✔️ Antihistamine triprolidine eases runny nose and sneezing
  • ✔️ Suitable for adults and young people aged 12 and over
  • ✔️ Convenient 100ml bottle for multi-day cold symptom relief

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What Is Actifed Dry Cough Syrup and How Does It Help?

 

A dry, tickly cough can be exhausting — especially when it lingers for days after a cold. Actifed dry cough syrup is an over-the-counter oral liquid designed to tackle exactly that. It combines three active ingredients to address not just the cough itself, but also the nasal congestion and irritation that so often come with it. Available in a convenient 100ml bottle, it's a practical option to keep in your medicine cabinet during cold and flu season. If you're looking for broader cold and flu relief products, you can explore our full cold and flu range at Cured Pharmacy.

Each 10ml dose contains dextromethorphan hydrobromide 10mg, pseudoephedrine hydrochloride 30mg, and triprolidine hydrochloride 1.25mg. These three ingredients work together to provide multi-symptom relief from the kind of dry, irritating cough that keeps you awake at night or disrupts your day.

 

How Does Actifed Dry Cough Syrup Work?

 

Understanding how a medicine works helps you use it with confidence. Actifed Dry Cough Syrup targets your symptoms through three distinct mechanisms:

  • Dextromethorphan hydrobromide — acts centrally on the cough centre in the brain to suppress the urge to cough. It's classed as an antitussive and is one of the most widely used cough suppressants available without prescription.
  • Pseudoephedrine hydrochloride — a sympathomimetic decongestant that works by constricting the blood vessels lining the nasal passages, reducing swelling and congestion.
  • Triprolidine hydrochloride — a first-generation antihistamine that helps relieve the runny nose, sneezing, and irritation that often accompany a cold-related cough.

Together, these ingredients address the root causes of your discomfort rather than masking a single symptom. That said, this syrup is specifically formulated for dry, non-productive coughs — not chesty or productive coughs where you're bringing up mucus.

 

Who Should Use Actifed Dry Cough Syrup?

 

This syrup is suitable for adults and young people aged 12 and over who are experiencing a dry, tickly cough associated with a cold or upper respiratory tract infection. It's particularly useful when congestion and coughing occur together. That said, it isn't right for everyone.

It may be suitable for you if you:

  • Are aged 12 years or over
  • Have a dry, non-productive cough (no mucus)
  • Are also experiencing nasal congestion or a runny nose
  • Are not taking MAOIs or other interacting medicines

It is not suitable for children under 12, people with certain heart conditions, uncontrolled high blood pressure, or those taking monoamine oxidase inhibitors (MAOIs). Always read the label carefully before use.

 

How Does Actifed Dry Cough Syrup Compare to Other Cough Medicines?

 

Feature Actifed Dry Cough Syrup Simple Linctus (e.g. Pholcodine)
Active ingredients Dextromethorphan, Pseudoephedrine, Triprolidine Pholcodine only
Targets congestion? Yes No
Antihistamine included? Yes No
Suitable for under 12s? No Depends on product

 

How Should You Store Actifed Dry Cough Syrup?

 

Store Actifed Dry Cough Syrup below 25°C, away from direct sunlight and heat. Keep the bottle tightly closed when not in use, and always store it out of the reach and sight of children. Do not use the product after the expiry date printed on the label.

If you're managing multiple cold symptoms at once, it's worth checking our ear, nose and throat range for complementary products. This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

Actifed Dry Cough Syrup 100ml specifications
Treatment category Cough and cold relief
Mechanism of action Antitussive, decongestant, antihistamine
Effective for Dry, tickly cough; nasal congestion; runny nose
Suitable for Adults and children aged 12 and over
Active ingredients Dextromethorphan hydrobromide 10mg/10ml, Pseudoephedrine hydrochloride 30mg/10ml, Triprolidine hydrochloride 1.25mg/10ml
Pack size 100ml
UK classification P (Pharmacy medicine)
Drug class Antitussive / Sympathomimetic decongestant / Antihistamine
Preparation Oral syrup
Route of administration Oral

Specifications of Actifed Dry Cough Syrup 100ml

 

What Is Actifed Dry Cough Syrup and What Is It Used For?

 

Actifed Dry Cough Syrup is a pharmacy (P) medicine used to relieve the symptoms of a dry, irritating cough alongside nasal congestion and a runny nose — symptoms commonly associated with colds and upper respiratory tract infections. It is an oral liquid taken by mouth and is available without a prescription for adults and children aged 12 and over. The NHS notes that most coughs caused by colds will clear up on their own within three weeks, but symptomatic relief can make a significant difference to your comfort and sleep quality in the meantime.

 

What Do You Need to Know Before Using Actifed Dry Cough Syrup?

 

Before taking this syrup, it's important to check whether it's appropriate for you. Do not take Actifed Dry Cough Syrup if any of the following apply:

  • You are under 12 years of age
  • You are pregnant or breastfeeding (seek medical advice first)
  • You are taking or have taken MAOIs (monoamine oxidase inhibitors) within the last 14 days
  • You have severe high blood pressure or severe coronary artery disease
  • You have hyperthyroidism (overactive thyroid)
  • You are allergic to any of the active or inactive ingredients
  • You have closed-angle glaucoma
  • You have difficulty urinating due to an enlarged prostate

You should also be aware of potential drug interactions. The following medicines may interact with Actifed Dry Cough Syrup:

  • MAOIs — risk of hypertensive crisis; do not combine
  • Other sympathomimetics (e.g. other decongestants) — increased cardiovascular risk
  • CNS depressants including alcohol, sedatives, and anxiolytics — increased drowsiness
  • Antihypertensive medicines — pseudoephedrine may reduce their effectiveness
  • Tricyclic antidepressants — may enhance the effects of pseudoephedrine

If you are unsure whether any of your current medicines interact with this product, speak to your pharmacist before use. You can also browse our pain relief range if you need additional symptom management alongside your cough treatment.

 

How Should You Use Actifed Dry Cough Syrup?

 

Always use this medicine exactly as directed on the label or as advised by your pharmacist. Do not exceed the recommended dose.

  1. Shake the bottle gently before each use.
  2. Measure the correct dose using the measuring cup or spoon provided — do not estimate.
  3. Swallow the syrup directly; do not dilute it.
  4. Space doses evenly throughout the day.
  5. Do not take more than four doses in any 24-hour period.
Age Group Dose Frequency Maximum daily dose
Adults and children aged 12+ 10ml Up to 4 times daily 40ml in 24 hours
Children under 12 Not suitable — do not use

 

What Are the Possible Side Effects of Actifed Dry Cough Syrup?

 

Like all medicines, Actifed Dry Cough Syrup can cause side effects, although not everyone will experience them. The NHS advises that you should always read the patient information leaflet supplied with your medicine and report any unexpected effects to your pharmacist or GP.

Common side effects (may affect up to 1 in 10 people):

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Dizziness
  • Nausea
  • Headache

Less common side effects (may affect up to 1 in 100 people):

  • Difficulty sleeping (insomnia) — more likely due to pseudoephedrine
  • Palpitations or increased heart rate
  • Urinary retention (difficulty passing urine)
  • Nervousness or restlessness
  • Skin rash or allergic reaction

Stop taking the syrup and seek immediate medical attention if you experience signs of a serious allergic reaction, such as swelling of the face, lips, or throat, difficulty breathing, or a severe skin reaction. Because triprolidine can cause drowsiness, avoid driving or operating heavy machinery until you know how this medicine affects you.

 

How Should You Store Actifed Dry Cough Syrup?

 

Correct storage helps maintain the medicine's effectiveness and safety. Follow these guidelines:

  • Store below 25°C in a cool, dry place
  • Keep away from direct sunlight and heat sources
  • Keep the bottle tightly closed after each use
  • Store out of the reach and sight of children
  • Do not use after the expiry date printed on the label
  • Do not dispose of medicines via wastewater or household waste — return unused medicine to your pharmacy

If you're managing cold symptoms alongside other health concerns, our vitamins and supplements range includes immune-support options that may complement your recovery.

Written and reviewed by our qualified team

Your safety and success are our highest priorities. Our medical team rigorously evaluates every product and piece of advice we provide, ensuring you receive only the most effective, science-backed solutions available.

Frequently Asked Questions

Where can I buy Actifed Dry Cough Syrup online in the UK?

You can buy Actifed Dry Cough Syrup 100ml directly from Cured Pharmacy, a GPhC-registered UK online pharmacy, for just £6.29. It's available without a prescription as a pharmacy (P) medicine. Browse our full cold and flu collection for related products too.

How does Actifed Dry Cough Syrup work in the body?

Actifed Dry Cough Syrup works through three active ingredients acting simultaneously. Dextromethorphan suppresses the cough reflex centrally in the brain, pseudoephedrine constricts nasal blood vessels to reduce congestion, and triprolidine blocks histamine receptors to ease runny nose and irritation. Together, they provide multi-symptom relief from cold-related dry coughs.

How do I use Actifed Dry Cough Syrup step by step?

Shake the bottle before use, then measure 10ml using the measuring cup provided. Swallow the dose directly without diluting it. Repeat up to four times daily, spacing doses evenly, and never exceed 40ml in any 24-hour period.

What is the correct dose of Actifed Dry Cough Syrup for adults?

Adults and children aged 12 and over should take 10ml up to four times daily. That equates to a maximum of 40ml in 24 hours. Do not take more than the recommended dose, and if symptoms persist beyond five days, consult your pharmacist or GP.

Can children under 12 take Actifed Dry Cough Syrup?

No — Actifed Dry Cough Syrup is not suitable for children under 12 years of age. If your child has a dry cough, speak to your pharmacist or GP about age-appropriate alternatives. You can also explore our baby and toddler range for suitable products.

What are the side effects of Actifed Dry Cough Syrup?

Common side effects include drowsiness, dry mouth, dizziness, nausea, and headache. Less commonly, you may experience insomnia, palpitations, or urinary retention. If you experience signs of a serious allergic reaction — such as facial swelling or difficulty breathing — stop use immediately and seek medical help.

How do I manage drowsiness caused by Actifed Dry Cough Syrup?

Drowsiness is caused by the antihistamine triprolidine in the formula. Avoid driving, cycling, or operating machinery until you know how the medicine affects you. Taking your dose in the evening may help you manage daytime drowsiness, but always follow the dosing schedule and do not exceed four doses in 24 hours.

Can I take Actifed Dry Cough Syrup with other medicines?

Do not take Actifed Dry Cough Syrup if you are currently taking or have taken MAOIs within the last 14 days, as this combination can cause a dangerous rise in blood pressure. It may also interact with other decongestants, sedatives, alcohol, antihypertensives, and tricyclic antidepressants. Always check with your pharmacist before combining medicines.

Is Actifed Dry Cough Syrup safe to take during pregnancy?

Actifed Dry Cough Syrup is not recommended during pregnancy or breastfeeding without specific medical advice. Pseudoephedrine in particular may not be appropriate during pregnancy. Always speak to your GP or midwife before taking any cough or cold medicine while pregnant or nursing.

How long can I use Actifed Dry Cough Syrup for?

This syrup is intended for short-term use only. If your cough has not improved after five days of use, or if it worsens at any point, stop taking the medicine and consult your GP or pharmacist. Prolonged use without medical supervision is not recommended.

What happens if I miss a dose of Actifed Dry Cough Syrup?

If you miss a dose, simply take it as soon as you remember — unless it's nearly time for your next dose. In that case, skip the missed dose and continue as normal. Never double up doses to make up for a missed one, as this could increase the risk of side effects.

What are the alternatives to Actifed Dry Cough Syrup?

Alternatives for dry cough relief include simple linctus, pholcodine-based syrups, or honey and lemon preparations for mild symptoms. However, most single-ingredient alternatives won't address congestion and antihistamine symptoms simultaneously. Speak to your pharmacist to find the most suitable option for your specific symptoms.

Who is eligible to buy Actifed Dry Cough Syrup?

Actifed Dry Cough Syrup is suitable for adults and young people aged 12 and over who have a dry, non-productive cough associated with a cold. It is not suitable for those with certain cardiovascular conditions, hyperthyroidism, glaucoma, or those taking MAOIs. If you have any underlying health conditions, check with your pharmacist before purchasing.

Can I drink alcohol while taking Actifed Dry Cough Syrup?

You should avoid alcohol while taking Actifed Dry Cough Syrup. Alcohol can significantly increase the sedative effects of triprolidine, making drowsiness worse and impairing your ability to drive or operate machinery safely. It's best to wait until you have finished your course of treatment before drinking alcohol.

What are the latest recommendations on treating dry coughs in the UK?

The NHS advises that most dry coughs caused by colds resolve within three weeks without treatment. Where symptomatic relief is needed, over-the-counter antitussive syrups like this dry cough syrup remain a widely recommended option by pharmacists. If a cough lasts longer than three weeks, is accompanied by blood, or causes chest pain, you should see your GP promptly.

How Should You Use Actifed Dry Cough Syrup?

Using Actifed Dry Cough Syrup correctly ensures you get the most from each dose while minimising the risk of side effects. Always read the label before use and follow the instructions carefully. If you have any questions, your pharmacist is the best person to ask.

Space your doses evenly throughout the day. Taking doses too close together increases the risk of side effects without improving symptom relief.

What Is the Correct Dose of Actifed Dry Cough Syrup?

The dose varies by age. Do not give this medicine to anyone under 12 years old. Always use the measuring device provided to ensure accuracy.

The maximum dose is 40ml in any 24-hour period. Do not exceed this, even if symptoms feel severe.

When Is the Best Time to Use Actifed Dry Cough Syrup?

There is no single "best" time — the key is to space your doses evenly across the day. However, because triprolidine can cause drowsiness, many people find it helpful to take one of their doses in the evening to aid sleep when a cough is most disruptive. If you find daytime drowsiness is a problem, consider whether your timing can be adjusted, but always maintain the correct interval between doses. Avoid taking a dose immediately before driving or operating machinery.

How Long Can You Use Actifed Dry Cough Syrup For?

Actifed Dry Cough Syrup is intended for short-term use only. Most cold-related dry coughs improve within a few days to a week. If your symptoms have not improved after five days of use, or if they worsen at any point, stop taking the syrup and speak to your GP or pharmacist. Do not use this medicine continuously for longer than directed without medical advice, as prolonged use of decongestants and antihistamines is not recommended without supervision.

Do not exceed the recommended dose. If in doubt, speak to your pharmacist.

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What Are the Most Common Side Effects of Actifed Dry Cough Syrup?

Like all medicines, Actifed Dry Cough Syrup can cause side effects in some people. The most common ones are linked to the antihistamine triprolidine and the decongestant pseudoephedrine. Most are mild and tend to resolve on their own as your body adjusts.

  • Drowsiness or sedation
  • Dry mouth, nose, or throat
  • Dizziness or light-headedness
  • Nausea
  • Headache

What Are the Less Common Side Effects of Actifed Dry Cough Syrup?

Some people may experience less common side effects, particularly those related to the stimulant effects of pseudoephedrine. These are more likely if you are sensitive to sympathomimetic medicines or if you take more than the recommended dose.

  • Difficulty sleeping (insomnia)
  • Palpitations or a faster than normal heartbeat
  • Nervousness or restlessness
  • Urinary retention (difficulty passing urine — more likely in men with an enlarged prostate)
  • Skin rash or itching
  • Blurred vision

What Are the Serious Side Effects of Actifed Dry Cough Syrup?

Serious side effects are rare but require immediate medical attention. Stop taking the syrup straight away and call 999 or go to your nearest A&E if you experience any of the following:

  • Signs of a severe allergic reaction — swelling of the face, lips, tongue, or throat; difficulty breathing; severe skin rash
  • A sudden, severe increase in blood pressure (symptoms may include a severe headache, blurred vision, or chest pain)
  • Irregular or very rapid heartbeat

These reactions are uncommon, but it's important to be aware of them. If you have a history of cardiovascular disease or high blood pressure, speak to your GP before using this product.

What Should You Do If You Experience Side Effects?

For mild side effects such as drowsiness or dry mouth, these often improve after the first day or two of use. Staying well hydrated can help with dry mouth. Avoid alcohol, as it significantly worsens drowsiness caused by triprolidine. Do not drive or operate machinery if you feel sedated. If side effects are troublesome or persistent, stop use and speak to your pharmacist — they can advise on whether to continue or switch to an alternative.

Can Actifed Dry Cough Syrup Interact With Other Medicines?

Yes. This syrup has several clinically significant interactions. The most important is with MAOIs (monoamine oxidase inhibitors) — combining these with pseudoephedrine can cause a dangerous hypertensive crisis. Do not take this syrup if you have taken an MAOI within the last 14 days. Other interactions include CNS depressants (which increase sedation), antihypertensive medicines (whose effects may be reduced), and tricyclic antidepressants. Always tell your pharmacist about all medicines, supplements, and herbal remedies you are taking before starting this product.

If you are concerned about any side effects, contact your pharmacist or GP immediately.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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