Our Pricing

Looking for safe, effective prescription weight loss treatment UK online? At Cured Pharmacy, we offer the full range of MHRA-licensed weight loss medications — including Mounjaro, Wegovy, and Saxenda — with transparent upfront pricing, free clinical assessment by UK prescribers, and discreet next-day delivery. All treatments require a clinical consultation to ensure suitability and safety.

How Prescription Weight Loss Medications Work

Modern prescription weight loss treatments in the UK fall into two main categories: GLP-1 receptor agonists (Mounjaro, Wegovy, Saxenda) and lipase inhibitors (Orlistat, Xenical). GLP-1 medications mimic natural gut hormones that regulate appetite and blood sugar, helping patients feel fuller for longer and reducing food cravings [1]. Mounjaro uniquely activates both GIP and GLP-1 receptors, producing dual metabolic effects that clinical trials show may lead to greater weight reduction compared to single-pathway treatments.

In the landmark SURMOUNT-1 trial, participants taking the highest tirzepatide dose achieved an average 22.5% body weight reduction over 72 weeks — the most substantial results seen in any obesity medication trial to date [1]. Semaglutide-based treatments like Wegovy demonstrated average weight loss of 14.9% over 68 weeks in the STEP 1 trial [2]. These medications work most effectively when combined with a reduced-calorie diet and increased physical activity, as recommended by NICE guidance.

Lipase inhibitors like Orlistat work through a completely different mechanism, blocking approximately 30% of dietary fat absorption in the intestine [3]. While typically producing more modest weight loss (average 3kg greater than placebo over 12 months), they remain a valuable option for patients who prefer oral medication or have contraindications to GLP-1 treatments.

Mounjaro, Wegovy, and Saxenda: Comparing GLP-1 Treatments

All three injectable treatments are licensed by the MHRA for chronic weight management in adults with a BMI of 30 or above, or 27 or above with weight-related health conditions. The key differences lie in their molecular structure, dosing frequency, and clinical efficacy data.

Mounjaro contains tirzepatide, the first dual GIP/GLP-1 receptor agonist available in the UK. This dual mechanism may explain why SURPASS and SURMOUNT trials consistently showed greater weight reduction compared to semaglutide in head-to-head studies [1][4]. Wegovy and Saxenda both contain forms of semaglutide and liraglutide respectively — proven GLP-1 agonists with extensive safety data spanning over a decade of clinical use.

Dosing schedules differ significantly: Mounjaro and Wegovy require just one subcutaneous injection weekly, whilst Saxenda requires daily injections. This convenience factor often influences patient preference and long-term adherence. Your UK prescriber will consider your medical history, previous treatment responses, and lifestyle factors when recommending the most suitable option.

Which GLP-1 Treatment Is Right for You?

The choice between Mounjaro, Wegovy, and Saxenda depends on multiple clinical factors. Patients seeking maximum weight reduction potential may be considered for Mounjaro, subject to prescriber assessment and suitability criteria. Those with established cardiovascular disease may benefit from semaglutide's proven cardiovascular outcomes data [2]. Cost considerations, injection frequency preferences, and individual tolerability all play important roles in treatment selection.

At Cured Pharmacy, our UK-registered prescribers conduct thorough assessments to determine which medication aligns best with your health profile and weight management goals. All three treatments require gradual dose escalation to minimise gastrointestinal side effects, and ongoing clinical monitoring ensures both safety and effectiveness throughout your treatment journey.

Orlistat and Xenical: Oral Weight Loss Medication Options

For patients who prefer oral medication or have contraindications to injectable treatments, Orlistat remains a clinically proven option licensed in the UK since 1998. Available as generic Orlistat or the branded Xenical formulation, this lipase inhibitor prevents approximately one-third of dietary fat from being absorbed during digestion [3].

Clinical trials demonstrate that Orlistat, when combined with a reduced-calorie, lower-fat diet, produces an average additional weight loss of 3kg compared to diet alone over 12 months [3]. Whilst more modest than GLP-1 results, this represents meaningful clinical benefit for appropriate patients. The medication works locally in the gut and is minimally absorbed systemically, making it suitable for patients with certain medical conditions that preclude GLP-1 use.

Orlistat requires three times daily dosing with meals and works best when dietary fat intake is distributed evenly throughout the day. Patients should be aware that unabsorbed fat may cause gastrointestinal effects including oily stools and increased bowel frequency — these effects actually reinforce dietary adherence, as they occur primarily when fat intake exceeds recommended levels. Lower-dose Orlistat formulations are also available for over-the-counter purchase under pharmacist supervision.

Who Should Consider Orlistat?

Orlistat may be particularly suitable for patients who prefer oral medication, have needle phobia, or experience intolerable side effects with GLP-1 treatments. It's also appropriate for those seeking a lower-cost option or who have medical histories that make injectable treatments less suitable. Your UK prescriber will assess your BMI, weight-related health conditions, previous weight loss attempts, and current medications to determine if Orlistat is the right choice for your circumstances.

Starting Your Weight Loss Treatment Journey at Cured Pharmacy

Beginning prescription weight loss treatment requires clinical assessment by a UK-registered prescriber to ensure safety and suitability. At Cured Pharmacy, our streamlined online consultation takes under three minutes to complete and covers your medical history, current medications, previous weight loss attempts, and treatment goals.

Our clinical team, led by Superintendent Pharmacist Tarun Kumar (GPhC 2233073), reviews every consultation individually. If treatment is deemed appropriate, your prescription is issued and dispensed from our UK-registered pharmacy (GPhC 9012511). We supply only genuine, UK-licensed medications sourced through regulated channels — never grey-market imports or unlicensed alternatives.

Once approved, your medication is dispatched in discreet, unmarked packaging with next-day delivery options available. We provide comprehensive patient information leaflets, injection technique guidance for injectable treatments, and ongoing support throughout your treatment course. Follow-up consultations ensure your medication remains suitable and effective as your weight loss progresses.

Pricing and Transparency: What You'll Pay at Cured Pharmacy

Unlike many online pharmacies that hide costs until after consultation, Cured Pharmacy displays transparent upfront pricing on every product page. Our weight loss treatments start from competitive rates, with Saxenda available from £135.00 Wegovy from £135.00 and Mounjaro from £135.00 per prescription cycle. These prices include your medication, clinical consultation, prescriber review, and discreet delivery.

We operate a lowest price guarantee across our range — if you find a lower price for the same UK-licensed medication from a registered UK pharmacy, we'll match it. There are no hidden fees, subscription traps, or mandatory ongoing commitments. You control your treatment timeline and can pause or adjust your prescription schedule through consultation with our clinical team.

Final pricing depends on your prescribed dose, which increases gradually according to clinical protocols. Your prescriber will explain the dose escalation schedule during your consultation, and you'll see exact pricing for each stage before proceeding. We also offer multi-month supply options where clinically appropriate, providing better value for patients established on maintenance doses.

Current Offers and Savings

Cured Pharmacy regularly offers savings on weight loss treatments, including £10 off your first prescription when you complete your online assessment. Check individual product pages for current promotional pricing and bundle offers. All discounts are applied automatically at checkout — no codes needed.

Safety, Side Effects, and Clinical Monitoring

All prescription weight loss medications carry potential side effects that must be understood before starting treatment. GLP-1 receptor agonists commonly cause gastrointestinal effects including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation phases [1][2]. These effects typically diminish over 4-8 weeks as your body adjusts to the medication. Eating smaller portions, avoiding high-fat foods, and staying well-hydrated can help minimise discomfort.

More serious but rare side effects include pancreatitis, gallbladder problems, and changes in heart rate. GLP-1 medications carry warnings regarding thyroid C-cell tumours based on animal studies, though no causal link has been established in humans [1]. Patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 should not use these treatments. Your prescriber will screen for these contraindications during your consultation.

Orlistat's side effects are primarily gastrointestinal and relate directly to its mechanism of blocking fat absorption [3]. Oily spotting, flatulence with discharge, and urgent bowel movements can occur, especially when dietary fat intake exceeds recommendations. These effects serve as a behavioural reinforcement to maintain a lower-fat diet. Orlistat may also reduce absorption of fat-soluble vitamins, so multivitamin supplementation is typically recommended.

Regular monitoring ensures your treatment remains safe and effective. At Cured Pharmacy, our clinical team conducts periodic reviews to assess weight loss progress, side effect tolerability, and any changes in your medical circumstances. We encourage patients to report any concerning symptoms promptly through our secure messaging system, and our pharmacists are available by phone during business hours for urgent queries.

When to Seek Medical Attention

Seek immediate medical attention if you experience severe abdominal pain that doesn't resolve, persistent vomiting preventing fluid intake, signs of allergic reaction, or sudden vision changes whilst taking weight loss medication. Contact your GP or our pharmacy team if you experience side effects that significantly impact your quality of life — alternative treatments or dose adjustments may be appropriate. Never discontinue prescription medication without consulting a healthcare professional.

Scientific References

1. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038
2. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183
3. Sjöström, L., Rissanen, A., Andersen, T., et al. (1998). Randomised placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. The Lancet, 352(9123), 167–172. https://doi.org/10.1016/S0140-6736(97)11509-4
4. Frias, J. P., Davies, M. J., Rosenstock, J., et al. (2021). Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. New England Journal of Medicine, 385(6), 503–515. https://doi.org/10.1056/NEJMoa2107519

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Individual results may vary, and weight loss outcomes depend on multiple factors including adherence to lifestyle modifications.