Mounjaro vs Saxenda UK: Which Works Best? | Cured

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Cheapest Mounjaro vs Saxenda UK Price £124.99

Compare Mounjaro and Saxenda at the cheapest UK price from £124.99 plus £20 off your first order with code Weightlossnew.

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Our Pricing

Pricing Disclaimer: Prices on some pages may not be up to date — the live pricing table below and pricing shown during consultation are official current prices and take precedence over any other figures on the site.

Mounjaro (Tirzepatide)
Weeks 1–4

2.5mg

1 pen • 4 Weeks

£145 £124.99

£31.25 / Per Week

Your starting dose – designed to help your body adjust gently to treatment

⭐ Future Orders at £145
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Mounjaro (Tirzepatide)
Weeks 5–8

5mg

1 pen • 4 Weeks

£179 £159.00

£39.75 / Per Week

First step up – builds on your progress as your body adapts to treatment

⭐ Future Orders at £179
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Mounjaro (Tirzepatide)
Weeks 9–12

7.5mg

1 pen • 4 Weeks

£220 £200.00

£50.00 / Per Week

Mid-range dose – for continued progression and enhanced results

⭐ Future Orders at £220
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Mounjaro (Tirzepatide)
Weeks 13–16

10mg

1 pen • 4 Weeks

£245 £225.00

£56.25 / Per Week

Higher strength dose – supports significant weight loss progress

⭐ Future Orders at £245
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Mounjaro (Tirzepatide)
Weeks 17–20

12.5mg

1 pen • 4 Weeks

£270 £250.00

£62.50 / Per Week

Advanced dose – for patients requiring stronger therapeutic effect

⭐ Future Orders at £270
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Mounjaro (Tirzepatide)
Weeks 21+

15mg

1 pen • 4 Weeks

£287 £267.00

£66.75 / Per Week

Maximum dose – the highest available strength for optimal results

⭐ Future Orders at £287
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Wegovy (Semaglutide)
Weeks 1–4

0.25mg

1 pen • 4 Weeks

£89 £69.00

£17.25 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £89
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Wegovy (Semaglutide)
Weeks 5–8

0.5mg

1 pen • 4 Weeks

£99 £79.00

£19.75 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £99
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Wegovy (Semaglutide)
Weeks 9–12

1mg

1 pen • 4 Weeks

£119 £99.00

£24.75 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £119
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Wegovy (Semaglutide)
Weeks 13–16

1.7mg

1 pen • 4 Weeks

£169 £149.00

£37.25 / Per Week

Higher strength – supports accelerated weight loss progress

⭐ Future Orders at £169
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Wegovy (Semaglutide)
Weeks 17+

2.4mg

1 pen • 4 Weeks

£199 £179.00

£44.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199
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Wegovy Oral Pill
Weeks 1–4

1.5mg

1 pen • 4 Weeks

£83.00 £63.00

£20.75 / Per Week

Your starting dose – eases your body into treatment with minimal side effects

⭐ Future Orders at £83.00
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Wegovy Oral Pill
Weeks 5–8

4mg

1 pen • 4 Weeks

£110.00 £90.00

£27.50 / Per Week

First step up – continues building tolerance for long-term success

⭐ Future Orders at £110.00
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Wegovy Oral Pill
Weeks 9–12

9mg

1 pen • 4 Weeks

£140.00 £120.00

£35.00 / Per Week

Mid-range dose – where most patients start seeing meaningful results

⭐ Future Orders at £140.00
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Wegovy Oral Pill
Weeks 13+

25mg

1 pen • 4 Weeks

£199.00 £179.00

£49.75 / Per Week

Maximum dose – the highest available strength for optimal weight management

⭐ Future Orders at £199.00
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Mounjaro vs Saxenda: Private Prescription UK

Published on: June 03, 2026

Choosing between Mounjaro vs Saxenda for a UK prescription requires understanding how these two injectable weight loss treatments differ in mechanism, efficacy, and suitability. At Cured Pharmacy, our UK-registered clinical team provides transparent comparisons and personalised prescriber assessments to help you access the most appropriate treatment, with prices starting from £135.00 for Saxenda and £135.00 for Mounjaro.

How Mounjaro and Saxenda Work Differently

Mounjaro contains tirzepatide, the first dual GIP/GLP-1 receptor agonist licensed by the MHRA for weight management in the UK [1]. This dual-action mechanism activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, enhancing insulin secretion, slowing gastric emptying, and reducing appetite through complementary pathways.

Saxenda, by contrast, contains liraglutide, a single GLP-1 receptor agonist that has been available in the UK since 2015 [2]. Liraglutide mimics the natural GLP-1 hormone to regulate blood sugar and suppress appetite, but operates through one pathway rather than two. Both treatments require subcutaneous injection and work by altering the hormonal signals that control hunger and satiety, though their pharmacological profiles differ substantially.

Clinical Efficacy: Mounjaro vs Saxenda Weight Loss Results

In head-to-head clinical comparisons, tirzepatide consistently demonstrates superior weight reduction outcomes. The SURMOUNT-1 trial showed patients taking the 15mg Mounjaro dose achieved an average body weight reduction of 22.5% over 72 weeks, compared to 2.4% with placebo [1]. For context, the SCALE Obesity and Prediabetes trial found liraglutide 3mg (Saxenda) produced an average weight loss of 8.4% over 56 weeks versus 2.8% with placebo [2].

While individual responses vary based on adherence, baseline metabolic health, and lifestyle factors, the dual-receptor mechanism of tirzepatide appears to produce greater average reductions in body weight across clinical populations. Both medications require ongoing treatment to maintain weight loss, and discontinuation typically results in weight regain [3]. Your UK prescriber will assess which treatment aligns with your weight loss goals, medical history, and tolerance for injection frequency.

Real-World Effectiveness in UK Patients

Clinical trial results represent controlled conditions, but real-world effectiveness depends on consistent adherence, dietary modifications, and physical activity. UK prescribers at Cured Pharmacy emphasise that both Mounjaro and Saxenda work best when combined with a reduced-calorie diet and increased exercise, as outlined in NICE guidance for obesity management [4]. Neither medication is a standalone solution, and patients who engage with structured lifestyle programmes typically achieve better long-term outcomes.

Dosing and Administration: Weekly vs Daily Injections

Mounjaro is administered once weekly using a pre-filled KwikPen injector, starting at 2.5mg and gradually increasing to a maintenance dose of 5mg, 10mg, or 15mg based on individual response and tolerability [1]. The weekly schedule offers convenience for patients who prefer fewer injections, though the dose escalation period typically spans 8 to 20 weeks to minimise gastrointestinal side effects.

Saxenda requires daily subcutaneous injection, beginning at 0.6mg and increasing by 0.6mg increments weekly until reaching the maintenance dose of 3mg daily [2]. The daily regimen provides more frequent dosing touchpoints, which some patients find helpful for routine adherence, while others prefer the simplicity of weekly administration. Both pens are designed for self-injection into the abdomen, thigh, or upper arm, and UK prescribers provide full injection technique guidance during your consultation.

Feature Mounjaro (Tirzepatide) Saxenda (Liraglutide)
Active Ingredient Tirzepatide (dual GIP/GLP-1 agonist) Liraglutide (GLP-1 agonist)
Injection Frequency Once weekly Once daily
Starting Dose 2.5mg weekly 0.6mg daily
Maintenance Dose 5mg, 10mg, or 15mg weekly 3mg daily
Average Weight Loss (Clinical Trials) Up to 22.5% over 72 weeks Up to 8.4% over 56 weeks
Price at Cured Pharmacy From £124.99 From £124.99
MHRA Approval Year 2023 (weight management) 2015 (weight management)

Side Effects and Tolerability Comparison

Both Mounjaro and Saxenda share a common side effect profile dominated by gastrointestinal symptoms, including nausea, vomiting, diarrhoea, constipation, and abdominal discomfort [1][2]. These effects are most pronounced during dose escalation and typically diminish over several weeks as the body adapts. In clinical trials, approximately 44% of tirzepatide patients and 39% of liraglutide patients experienced nausea, though severe cases leading to discontinuation were less common.

Rarer but serious adverse effects include pancreatitis, gallbladder disease, and hypoglycaemia (particularly in patients taking concurrent diabetes medications). Both treatments carry a boxed warning regarding thyroid C-cell tumours observed in rodent studies, and neither should be used in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 [3]. Your UK prescriber will review your full medical history to identify any contraindications before issuing a prescription.

Managing Side Effects During Treatment

UK clinical guidance recommends eating smaller, more frequent meals, avoiding high-fat foods, and staying well-hydrated to mitigate gastrointestinal symptoms. If side effects become intolerable, your prescriber may adjust the dose escalation schedule or consider switching treatments. Superintendent pharmacist Tarun Kumar (GPhC 2233073) and the Cured Pharmacy clinical team provide ongoing support throughout your treatment journey, ensuring any concerns are addressed promptly.

Cost and Accessibility: Private Prescription Pricing UK

At Cured Pharmacy, Mounjaro is available from £124.99 per pen, with final cost determined by your prescribed dose and treatment duration. Saxenda starts from £135.00 reflecting its longer market presence and different dosing structure. Both medications require a private prescription in the UK, as they are not routinely available on the NHS for weight management outside specific specialist services.

Transparent upfront pricing is a core principle at Cured Pharmacy — you'll see exact costs before completing your free online consultation, with no hidden fees or surprise charges. Our UK-registered prescribers assess your eligibility based on BMI, comorbidities, and previous weight loss attempts, ensuring you receive a clinically appropriate recommendation rather than a sales-driven decision. All treatments are dispensed as genuine UK-licensed medicines with full regulatory approval.

Which Treatment Is Right for You?

Choosing between Mounjaro and Saxenda depends on your weight loss targets, tolerance for injection frequency, budget, and individual response to GLP-1 therapies. Patients seeking maximum weight reduction and willing to invest in newer dual-agonist technology may prefer Mounjaro, while those prioritising lower upfront cost or familiarity with established treatments may opt for Saxenda.

Your UK prescriber will evaluate your BMI (typically ≥30 kg/m², or ≥27 kg/m² with weight-related comorbidities), previous weight management efforts, and any contraindications such as diabetic retinopathy or severe gastrointestinal disease [4]. If one treatment is unsuitable or poorly tolerated, alternatives like Wegovy (semaglutide) or oral options such as Orlistat may be considered. The consultation process at Cured Pharmacy takes under three minutes, with prescriptions issued the same day subject to clinical approval.

Starting Your Weight Loss Journey at Cured Pharmacy

Begin by completing our free online assessment, which asks about your medical history, current medications, and weight loss goals. A UK-registered prescriber reviews your submission and determines the most suitable treatment, issuing a prescription if clinically appropriate. Your medication is then dispensed by our GPhC-registered pharmacy (9012511) and delivered in 100% discreet packaging, typically within 1-3 working days across the UK.

Scientific References

  1. Jastreboff, A. M., Aronne, L. J., Ahmad, N. N., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), 205–216. https://doi.org/10.1056/NEJMoa2206038 [accessed 13 August 2026]
  2. Pi-Sunyer, X., Astrup, A., Fujioka, K., et al. (2015). A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. New England Journal of Medicine, 373(1), 11–22. https://doi.org/10.1056/NEJMoa1411892 [accessed 13 August 2026]
  3. Wilding, J. P. H., Batterham, R. L., Calanna, S., et al. (2021). Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183 [accessed 13 August 2026]
  4. National Institute for Health and Care Excellence. (2023). Obesity: identification, assessment and management (CG189). NICE. https://www.nice.org.uk/guidance/cg189 [accessed 13 August 2026]
  5. NHS. (2026). Tirzepatide: a medicine to manage type 2 diabetes and treat obesity. https://www.nhs.uk/medicines/tirzepatide/ Accessed 13 August 2026.
  6. NHS. (2026). Overweight and obesity in adults. https://www.nhs.uk/conditions/overweight-and-obesity/ Accessed 13 August 2026.
  7. NHS England. (2026). Weight management injections. https://www.england.nhs.uk/ourwork/prevention/obesity/medicines-for-obesity/weight-management-injections/ Accessed 13 August 2026.

Information on this page is for educational purposes only and is not medical advice. All prescription treatments require clinical assessment by a UK-registered prescriber. Always consult a qualified healthcare professional before starting any new medication. Mounjaro and Saxenda are prescription-only medicines that must be prescribed following a consultation with a registered UK clinician who will assess your suitability based on your individual medical history and weight management needs.

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Jane L.

"Brilliant. Lost 4 stone on mounjaro no side effects at all. Cured pharmacy are excellent. Always helpful pens sent out quickly always comes with needles and sterile wipes. If you want to go on GLP-1 go to cured pharmacy. So professional. Thank you cured pharmacy you changed my health and well being."

Ann-Marie

"I absolutely love this product, I have been using 2.5mg as maintenance dose and have managed to control my weight without any side effects and can still eat well balanced meals. The pharmacy is very efficient friendly and helpful I would not purchase from anywhere else."

Sacha W.

"So far I'm really impressed by my results it's crazy cause I'm not snacking like how I used to do and I see my face slimming down already and it's only been 2 and a half weeks. Can't wait to give my feedback in 5 months time thank you cured pharmacy."

Kimberly G.

"Mounjaro has corrected my hormonal weight gain during menopause. I am using it now to maintain that balance. The results for me have been exceptional!"

Jennifer

"Great really helps cure those nasty habits can't wait for my next mounjaro pen."

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Faq

Is Mounjaro better than Saxenda for weight loss?
Clinical trials show Mounjaro (tirzepatide) produces greater average weight reduction than Saxenda (liraglutide), with up to 22.5% body weight loss versus 8.4% respectively. However, individual suitability depends on your medical history, tolerance, and prescriber assessment.
Can I switch from Saxenda to Mounjaro?
Yes, switching between treatments is possible under UK prescriber supervision. Your clinician will assess your response to Saxenda, any side effects experienced, and whether Mounjaro's dual-receptor mechanism may offer additional benefit before authorising a switch.
How long does it take to see results with Mounjaro vs Saxenda?
Most patients notice appetite suppression within the first 1-2 weeks of either treatment, with measurable weight loss typically evident by week 4-8. Maximum efficacy is usually achieved after several months of dose escalation and consistent adherence.
Do I need a prescription for Mounjaro or Saxenda in the UK?
Yes, both are prescription-only medicines (POMs) in the UK and require clinical assessment by a registered prescriber. Cured Pharmacy provides a free online consultation with UK prescribers who can issue private prescriptions if clinically appropriate.
What are the main side effects of Mounjaro vs Saxenda?
Both cause similar gastrointestinal side effects including nausea, vomiting, diarrhoea, and constipation, most common during dose escalation. Serious but rare risks include pancreatitis, gallbladder disease, and thyroid C-cell tumours (observed in animal studies).
Can I use Mounjaro or Saxenda if I have type 2 diabetes?
Mounjaro is licensed for both type 2 diabetes and weight management, while Saxenda is licensed only for weight management (a different liraglutide product, Victoza, is used for diabetes). Your UK prescriber will assess your diabetic control and concurrent medications before prescribing.
How much does Mounjaro vs Saxenda cost privately in the UK?
At Cured Pharmacy, Mounjaro starts from £124.99 and Saxenda from £135.00 with final cost depending on your prescribed dose and treatment duration. Prices are shown upfront before you complete your consultation, with no hidden fees.
Will I regain weight after stopping Mounjaro or Saxenda?
Clinical evidence shows most patients experience weight regain after discontinuing GLP-1 treatments, as the hormonal appetite suppression ceases. Long-term weight maintenance typically requires ongoing treatment combined with sustained lifestyle changes including diet and exercise.
Which is cheaper in the UK - Mounjaro or Saxenda?
Mounjaro starts from £124.99 at Cured Pharmacy, while Saxenda typically costs more per month for comparable weight loss results. Mounjaro is administered once weekly, whereas Saxenda requires daily injections, making Mounjaro more cost-effective and convenient for most patients.
Can I switch from Saxenda to Mounjaro with a UK prescription?
Yes, you can switch from Saxenda to Mounjaro through Cured Pharmacy after a consultation with a UK-registered prescriber. The prescriber will review your Saxenda experience and determine the appropriate starting dose of Mounjaro, typically beginning at 2.5mg weekly.
Is Mounjaro more effective than Saxenda for weight loss?
Clinical trials show Mounjaro (tirzepatide) delivers greater average weight loss than Saxenda (liraglutide), with patients losing up to 20% body weight on Mounjaro versus 5-10% on Saxenda. Cured Pharmacy offers both medications with prescriber support to help you choose the most suitable option.
How do I get a UK prescription for Mounjaro instead of Saxenda?
Cured Pharmacy provides online consultations with UK-registered prescribers who can assess whether Mounjaro or Saxenda is right for you. Complete the health questionnaire, and if suitable, your prescription will be issued and dispensed with next-day delivery available across the UK.
Does Mounjaro have the same side effects as Saxenda?
Both Mounjaro and Saxenda are GLP-1 based medications with similar side effects including nausea, diarrhoea, and reduced appetite. However, Mounjaro also targets GIP receptors, which may result in different tolerability for some patients. Cured Pharmacy prescribers will discuss your medical history to determine the best choice for you.
Tarun Kumar, Prescribing Pharmacist

Medically reviewed by

Tarun Kumar, Prescribing Pharmacist (GPhC 2233073)

Reviewed on: June 03, 2026

Last reviewed: 13 August 2026

Last updated on 13 August 2026.

Review History

Our experts continually monitor new findings in health and medicine, and we update our articles when new information becomes available.

Why this page was updated on 13 August 2026

Content checked and updated as part of our periodic review, to ensure accuracy and currentness.

Current version (13 August 2026)

Edited by: The Editorial Team

Medically reviewed by:

Tarun Kumar, GPhC No. 2233073, Prescribing Pharmacist


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