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Silkis Ointment 3mcg 100g (Calcitriol)

Silkis Ointment 3mcg 100g (Calcitriol)

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Silkis Calcitriol Ointment for Psoriasis Treatment

 

You can use Silkis ointment to treat mild to moderate plaque psoriasis affecting your skin. This prescription medicine contains calcitriol, a synthetic form of vitamin D3 that helps regulate skin cell growth and reduce inflammation. The ointment comes in a 100g tube containing 3 micrograms of calcitriol per gram.

Silkis ointment is specifically formulated for topical application to psoriatic plaques on your body and limbs. You should not apply this medicine to your face, scalp, or areas where your skin folds naturally. The treatment works by slowing down the rapid skin cell production that characterises psoriasis whilst reducing the inflammatory response in affected areas.

 

How Calcitriol Works on Psoriatic Skin

 

Calcitriol works by binding to vitamin D receptors in your skin cells, which helps normalise the rate at which your skin cells grow and shed. In psoriasis, your skin cells multiply too quickly, creating the thick, scaly patches characteristic of this condition. By regulating this process, calcitriol ointment helps reduce the thickness and scaling of psoriatic plaques.

The active ingredient also has anti-inflammatory properties that help reduce the redness and irritation associated with psoriatic lesions. This dual action makes calcitriol particularly effective for managing the symptoms of plaque psoriasis when used as directed by your healthcare provider.

 

Who Can Benefit from Silkis Treatment

 

Silkis ointment is suitable for adults with mild to moderate plaque psoriasis who need targeted topical treatment. Your doctor may prescribe this medicine if you have psoriatic plaques covering a limited area of your body surface. The treatment is particularly useful when you need an alternative to topical corticosteroids or as part of a combination therapy approach.

This medicine may be appropriate for you if you experience:

  • Localised psoriatic plaques on your trunk, arms, or legs
  • Mild to moderate psoriasis symptoms that require topical management
  • The need for a non-steroidal topical treatment option
  • Psoriasis that has responded well to vitamin D analogues previously

You can explore other skin care treatments available through our pharmacy if you need additional support for your skin condition management.

 

Why Choose a Vitamin D Analogue Treatment

 

Vitamin D analogues like calcitriol offer you a different mechanism of action compared to topical corticosteroids. This means you can use them for longer periods without the same concerns about skin thinning or other steroid-related side effects. The treatment provides sustained benefits for psoriasis management when used consistently as part of your prescribed regimen.

Calcitriol ointment can be particularly beneficial if you need to avoid or reduce your use of topical steroids. The medicine works gradually to improve your psoriatic symptoms, with many patients noticing improvements in plaque thickness and scaling within several weeks of regular use.

 

Clinical Suitability and Storage Requirements

 

You should store Silkis ointment at room temperature, away from direct heat and light. Keep the tube tightly closed when not in use and ensure it remains out of reach of children. The ointment should not be frozen, and you should check the expiry date before each use.

Your doctor will assess your suitability for this treatment based on your medical history, current medications, and the extent of your psoriasis. Regular monitoring may be required during treatment, particularly if you are using the ointment over large areas of your body or for extended periods.

This product is a medicine. Speak to your doctor or pharmacist before using if you have an underlying medical condition or are taking other medicines.

 

How to Apply Silkis Ointment Correctly

You should apply Silkis ointment twice daily to the affected areas of your skin, typically in the morning and evening. Clean and dry the affected area thoroughly before application. Apply a thin layer of ointment to the psoriatic plaques only, avoiding healthy skin around the lesions. Gently rub the ointment into your skin until it is absorbed.

Important Application Guidelines and Precautions

You must not exceed the maximum recommended weekly dose as advised by your doctor, which is typically no more than 100g per week. Wash your hands thoroughly after applying the ointment unless you are treating your hands. Avoid applying the medicine to your face, scalp, or skin folds such as under your arms or in your groin area. Do not cover the treated areas with occlusive dressings unless specifically instructed by your healthcare provider.

Understanding Potential Side Effects of Silkis

Like all medicines, Silkis ointment can have side effects, although not everyone will experience them. You can find additional support for managing skin conditions through our range of creams and ointments if you need complementary care products.

The most commonly reported side effects include local skin reactions at the application site, such as mild irritation, burning, or itching. These effects are usually temporary and may decrease as your skin becomes accustomed to the treatment.

Possible side effects you may experience include:

  • Skin irritation or burning sensation at application sites
  • Itching or pruritus in treated areas
  • Redness or erythema around psoriatic plaques
  • Dry skin or increased skin sensitivity
  • Worsening of psoriasis symptoms initially
  • Contact dermatitis in sensitive individuals
  • Skin discolouration at treatment sites
  • Elevated calcium levels in blood with excessive use
  • Kidney problems with prolonged overuse
  • Headache in some patients
  • Nausea or digestive upset rarely
  • Fatigue or weakness with systemic absorption

If you experience these or any other side effects, speak to your doctor or pharmacist right away. For more information about reporting side effects please see the MHRA Yellow Card Scheme.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Written and reviewed by our qualified team

GPhC Number: 2233073
Tarun Kumar

Reviewed by:

Tarun Kumar

Superintendent/ Clinical Lead

📖 Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 31 Mar 2025

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